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Introduction
He has completed his B. Pharm and M. Pharm course from University of Dhaka. His core interest resides in drug discovery employing natural product chemistry. He is currently doing researches on in vivo and in vitro testing of several phytochemicals along with crude extracts validated by molecular docking techniques. He has also eminent interest in cancer biology research, gene mutation and molecular biology.
ORCID: 0000-0002-1831-2278, Web of Science Researcher ID: AAV-1816-2020
Current institution
Additional affiliations
May 2022 - present
January 2020 - May 2022
Education
January 2013 - May 2019
Publications
Publications (76)
Millettia peguensis, popular for its ethnopharmacological uses, was employed to evaluate its different pharmacological properties in this study. The analgesic studies of the plant have been performed by acetic acid-induced writhing and formalin-induced licking tests respectively, whereas the antidiarrheal experiment was done by castor oil-induced d...
Background
Colocasia gigantea , locally named as kochu is well-known due to its various healing power. This research is to investigate the antidiarrheal, antimicrobial and antioxidant possibilities of the methanol soluble extract of Colocasia gigantea .
Methods
The antidiarrheal investigation was performed by using in vivo castor oil-induced diarr...
SARS-CoV-2 is the latest worldwide pandemic declared by the World Health Organization and there is no established anti-COVID-19 drug to combat this notorious situation except some recently approved vaccines. By affecting the global public health sector, this viral infection has created a disastrous situation associated with high morbidity and morta...
Diabetes, a chronic physiological dysfunction affecting people of different age groups and severely impairs the harmony of peoples’ normal life worldwide. Despite the availability of insulin preparations and several synthetic oral antidiabetic drugs, there is a crucial need for the discovery and development of novel antidiabetic drugs because of th...
Background
Colocasia affinis Schott and Colocasia gigantea Hook.f. are two commonly found vegetable species of the genus Colocasia, found mainly in the Asian region.
Objectives
The objective of this study was to isolate bioactive phytochemicals from C. affinis and C. gigantea and elucidate their structure employing the NMR technique followed by bi...
Introduction
ZnO nanoparticles (NPs) have garnered significant attention due to their remarkable multifunctionality, particularly in biomedical and environmental applications.
Methods
The study synthesized ZnO NPs using Citrus reticulata Blanco peel extracts. The structural, morphological, and optical properties of ZnO NPs have been analyzed. The...
Background: Cheilocostus speciosus (J. Koenig) C. Specht, commonly known as “Crepe‐ginger”, is a traditional plant with edible flowers utilized in folk medicine. This study employs crepe‐ginger flowers to evaluate their role in boosting liver immunity, hepatoprotective actions through oxidative stress management. Methods: Cheilocostus speciosus flo...
Introduction: Ethnomedicinal plants in Asia offer a promising, low‐side‐effect alternative to synthetic drugs for treating fungal infections, one of the most widespread communicable diseases caused by pathogenic fungi. Despite being underexplored, the region's rich plant diversity holds the potential for developing effective antifungal drugs. Resea...
Background: Diabetes is the most common chronic disease worldwide, requiring lifelong medication support. As conventional medications have numerous long-term side effects, herbal drugs, which offer similar effectiveness but fewer complications, are considered an alternative. A common tropical herb, Eclipta prostrata, was tested for its antidiabetic...
Introduction:
Baccaurea motleyana Müll. Arg. (Rambai), an Asian fruit belonging to the Phyllanthaceae family, is cultivated throughout Southeast Asia and has been traditionally utilized in folk medicine to address eye discomfort, digestive issues, insomnia, and fevers.
Methods:
This study of the peel employed four Kupchan fractions (PSF, DSF, ES...
Background
Throughout history, plants have played a crucial role in advancing medicinal treatments by providing a diverse range of compounds for the development of innovative therapies. Canna indica L. a tropical herb of the Cannaceae family, also known as Indian shot, has a rich history of traditional use in treating ailments like inflammation, ma...
Bangladesh is endowed with an abundance of excellent medicinal plant resources. A well‐known traditional medicinal plant Piper chaba H. from the Piperaceae family is rich in bioactive phytochemicals that have antidiarrheal, antimicrobial, analgesic, antioxidant, anticancer, and cytotoxic effects. This plant is locally known as “Chuijhal,” and the s...
Aims: Increased oxidative stress in diabetes mellitus may lead to splenic damage, contributing to decreased immunity. This study aims to evaluate the potential of vitamin E supplements as a protective agent against spleen injury by examining physiological, hematological, biochemical, and histological changes in diabetic rat model.
Methods: Diabet...
Clitoria ternatea L. (CT) is a perennial herbaceous plant with deep blue flowers native to tropical Asia. This work explores the endometrial pain (EP) regulation of CT flower through a multifaceted approach. Phytochemical screening unveiled the presence of alkaloids, steroids, flavonoids, glycosides, and tannins in CT flower methanolic extract (ME)...
Natural products have perennially served as a cornerstone for the genesis of novel medicinal compounds. Most clinical therapeutics originate from ancestral herbal remedies and their formulations. Scholars and practitioners have always aimed to extract better remedies to treat various ailments. Genus Ficus, consisting of over 800 varieties, is a sub...
Current study focused on Merremia vitifolia an ethnomedicinal plant, aiming to explore its medicinal properties comprehensively. Through qualitative and quantitative analysis, the study investigated the phytochemical components of M. vitifolia stem extract and assessed its antioxi-dant, anti-inflammatory, analgesic, antidepressant, anxiolytic, loco...
Background
Shirakiopsis indica (Willd)., commonly known as Sa-Mor-Ta-Lay in Thailand, is a mangrove plant belonging to the Euphorbiaceae family. As mangrove plants’ medicinal potentials are less explored, this study sought to qualitatively and quantitatively verify the bioactive components of Shirakiopsis indica fruits methanolic extract (SIF-ME) a...
Water hyacinth (Eichhornia crassipes (Mart.) Solms) is a highly invasive aquatic weed native to the Amazonia basin, known for its rapid propagation, adaptability and utilization in traditional medicine. The study aims to unveil the therapeutic potential of water hyacinth flowers methanolic extract (EC‐CME) and its four kupchan fractions (EC‐PESF, E...
Introduction: Colocasia affinis Schott (Family: Araceae), found in the Asian region, is a traditional root vegetable consumed by the locals and well-known as Dwarf Elephant Ear.
Methods: For the pharmacological exploration of this root vegetable, four kupchan fractions (i.e. HSF, DCMSF, EASF, and AQSF) from ethanolic extract of C. affinis were empl...
The imprudent use of antibiotics increases the environmental microflora's resistance to various drugs, particularly antibiotics. Prescription data is crucial for understanding antibiotic usage frequency and dosage. This health-focused study aims to analyze antibiotic prescription patterns in human and veterinary practices to identify emerging trend...
Numerous prior studies have identified therapeutic targets that could effectively combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, including the angiotensin-converting enzyme 2 (ACE2) receptor, RNA-dependent RNA polymerase (RdRp), and Main protease (Mpro). In parallel, antiviral compounds like abacavir, acyclovir, adef...
The imprudent use of antibiotics increases the environmental microflora’s resistance to various drugs, particularly antibiotics. Prescription data is crucial for understanding antibiotic usage frequency and dosage. This health-focused study aims to analyze antibiotic prescription patterns in human and veterinary practices to identify emerging trend...
Flavonoids are organic compounds characterized by a range of phenolic structures, which are abundantly present in various natural sources such as fruits, vegetables, cereals, bark, roots, stems, flowers, tea, and wine. The health advantages of these natural substances are renowned, and initiatives are being taken to extract the flavonoids. Apigenin...
Introduction: Natural plant-based medicines have gained popularity recently as a major source of inventive, risk-free, and more potent secondary bioactive compounds with medicinal potential. Catharanthus ovalis is a perennial shrub containing various indole alkaloids cultivated extensively for local medical purposes.
Methods: This research is condu...
Introduction: Plants and their extracts have been integral to the development of medicinal treatments throughout history, offering a vast array of compounds for innovative therapies. Baccaurea motleyana Müll. Arg., commonly known as Rambai, is an evergreen tree with economic importance in the Old-World Tropics.
Method: The study investigates its ph...
Crinum asiaticum L. (Amaryllidaceae) is a perennial bulbous herb, locally utilized for possessing multifaceted pharmacological properties including anticancer, immune-stimulating, analgesic, antiviral, antimalarial, antibacterial and antifungal, in addition to its popularity as an aesthetic plant. Separation of MeOH extract of C. asiaticum leaves y...
Carvacrol, a widely extracted monoterpenoid phenol from an abundant number of aromatic plant species including thyme and oregano. At present, carvacrol is being utilized in low concentrations as a preservative and food flavoring agent, in addition to serving as a fragrance element in cosmetic formulations. A great deal of study has been done in rec...
Since the first case of coronavirus disease (COVID-19) was reported in December 2019, it has become a pandemic, which is one of the most severe global health crises. In 2022, more than 100 million people in around 210 countries have been reported to be infected and about two million people have been reported to have died because of COVID-19. Then,...
Diabetes mellitus (DM) is a condition characterized by excessive blood sugar levels, which have recently reached the level of a pandemic. There are various side effects of each drug to treat this condition. Molecular docking is a modern concept for computer-aided drug designing. Using this technique several potential antidiabetic phytocompounds are...
p-coumaric acid, commonly referred to as 4-hydroxycinnamic acid, is a phenolic acid, which has been subjected to much research in recognition of its beneficial properties against several diseases and its widespread distribution in the plant kingdom. This compound can be found in the free-state or coupled with other molecules in nature. It has demon...
p-coumaric acid, commonly referred to as 4-hydroxycinnamic acid, is a phenolic acid, which has been subjected to much research in recognition of its beneficial properties against several diseases and its widespread distribution in the plant kingdom. This compound can be found in the free-state or coupled with other molecules in nature. It has demon...
Crinum asiaticum L. (Amaryllidaceae) is a perennial bulbous herb, locally utilized for possessing multifaceted pharmacological properties including anticancer, immune-stimulating, analgesic, antiviral, antimalarial, antibacterial, and antifungal, in addition to their popularity as an aesthetic plant. Separation of MeOH extract of C. asiaticum leave...
The pharmacological actions of benzylisoquinoline alkaloids are quite substantial, and have recently attracted much attention. One of the principle benzylisoquinoline alkaloids has been found in the unripe seed capsules of Papaver somniferum L. Although it lacks analgesic effects and is unrelated to the compounds in the morphine class, it is a peri...
Background:
The river Buriganga, one of the major dumping zones of industrial wastes in Bangladesh, is responsible for contaminating the drinking water sources along its length. This study aimed to assess the water quality from these sources by monitoring the changes in hematological, biochemical, and histological parameters caused in healthy rats...
Phoenix sylvestris Roxb. (Arecaceae) seeds are used in the treatment of diabetes in the traditional system of medicine. The present study evaluated antihyperglyce-mic and antioxidant activities as well as the total phenolic and flavonoid content of the methanol extract of P. sylvestris seeds (MEPS). The constituents of the extract were identified b...
Diabetes mellitus is a life-threatening disorder affecting people of all ages and adversely disrupts their daily functions. Despite the availability of numerous synthetic-antidiabetic medications and insulin, the demand for the development of novel antidiabetic medications is increasing due to the adverse effects and growth of resistance to commerc...
The natural spread of various harmful organisms into the environment has resulted in a wide range of diseases worldwide, including in Bangladesh. In December 2019, the world was exposed to a new virus-mediated sickness known as coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which has mostly a...
Piper betle L. leaves are very popular and traditionally used to chew with betel nut in many Asian countries. In this study, P. betle leaves juice (PBJ) was subjected to evaluation for its antihyperlipidemic activity in the high-fat-diet-induced hyperlipidemic rats model. Swiss albino rats were allowed to high-fat- diet for one month, followed by c...
Plants are serving the mankind with important bioactive phytochemicals from the very ancient ages to develop novel therapeutics against different disease states. Glycosmis cyanocarpa (Blume) Spreng is a plant from the Rutaceae family and a very less explored species from the Glycosmis genus. Thus, this present study was intended to present the chem...
Blumea lacera (Burm.f.) DC., popular for its traditional use in di erent diseases, was employed in phytochemical and biological investigations. e chemical studies led to the isolation of acyclic diterpene-phytol (1) along with two fatty acids-linolenic acid (2) and oleic acid (3). All the structures were determined by 1 H NMR spectroscopic analysis...
Aphananthe Aspera (Thunb.) Planch. is a towering woody deciduous tree and belongs to riparian forest territory. It is highly allocated to the Northern region of Eastern Asia especially Korea, China, Northern Vietnam, and Japan to be the richest countries with this species. The plants were assayed based on various types of methods including extracti...
Naproxen is a non-steroidal anti-inflammatory drug (NSAID) working as a non-selective cyclooxygenase (COX) inhibitor to treat inflammation, pain, fever, and various disease conditions. The current study was conducted to determine and compare several in vitro quality parameters, often commercially available 500 mg naproxen brands available in Bangla...
Autism spectrum disorder (ASD) is a neurological disorder that affects normal brain development. The recent finding of the microbiota–gut–brain axis indicates the bidirectional connection between our gut and brain, demonstrating that gut microbiota can influence many neurological disorders such as autism. Most autistic patients suffer from gastroin...
Dillenia pentagyna Roxb. is traditionally used to treat cancer, wound healing, diabetes, and diarrhea in local tribes. This study was designed to evaluate the pharmacological potentiality of this plant. In vivo analgesic, anti-inflammatory, and antipyretic studies of the methanol extracts of D. pentagyna (MEDP) leaves were performed by using acetic...
Medicinal plants have considerable potential as antimicrobial agents due to the presence of secondary metabolites. This comprehensive overview aims to summarize the classification, morphology, and ethnobotanical uses of Euphorbia neriifolia L. and its derived phytochemicals with the recent updates on the pharmacological properties against emerging...
This study intends to evaluate the development, importance, pre-clinical and clinical study evaluation of stem cell therapy for the treatment of cardiovascular disease. Cardiovascular disease is one of the main causes of fatality in the whole world. Though there are great progressions in the pharmacological and other interventional treatment option...
Gynura nepalensis D.C. (family: Asteraceae) has abundant uses in the alternative medicinal practice, and this species is commonly used in the treatment of diabetes, rheumatism, cuts or wounds, asthma, kidney stones, cough, urinary tract bleeding, gall bladder stones, hepatitis, diarrhea, hemorrhoids, constipation, vomiting, fertility problems, bloo...
Viral diseases are extremely widespread infections caused by viruses. Amongst numerous other illnesses, viral infections have challenged human existence severely. Over the history of mankind, new viruses have emerged and presented us with new tests. The range of viral infections varies from familiar infectious diseases such as the common cold, flu,...
The first appearance of COVID-19 from Wuhan, China, has now showed up with changed variants, resulting in millions of fatalities, billions of job losses, and remarkable economic damage by spreading across the world. It has been consistently evolved into more severe categories with its newfangled and fast-spreading mutant variants while entering its...
Leaves of Bruguiera gymnorhiza (L.) Lam. are very popular traditional remedies used by tribal people of Bangladesh near to Sundarbans. The purpose of this work was to assess the pharmacological attributes of methanolic extract of leaves of B. gymnorrhiza employing mice model. Using the well-known tail tipping method, the in vivo glucose-lowering ab...
Tamarind or Tamarindus indica L. is a multipurpose plant distributed throughout the tropics including Bangladesh. The present study was conducted to establish the preliminary antioxidant, antimicrobial, anti-inflammatory and thrombolytic activities of methanol extract of T. indica seeds along with its Kupchan fractions. To evaluate the antioxidant...
Steam inhalation therapy can be a contemporary approach for COVID-19 affected patients of all age groups to manage respiratory conditions, though it presently lacks the scientific backing to establish itself as a befitting practice. The age of COVID-19 has facilitated this traditional home remedy to resurface among the general mass as a helpful app...
Bauhinia scandens L. (Family: Fabaceae) is commonly used to treat cholera, diarrhea, asthma, and diabetes disorder in integrative medicine. This study aimed to screen the presence of phytochemicals (preliminary and UPLC-QTOF–M.S. analysis) and to examine the pharmacological activities of Bauhinia scandens L. stems (MEBS) stem extracts. Besides, in...
Bauhinia scandens L. (Family, Fabaceae) is a medicinal plant used for conventional and societal medication in Ayurveda. The present study has been conducted to screen the chemical, pharmacological and biochemical potentiality of the methanol extracts of B. scandens stems (MEBS) along with its related fractions including carbon tetrachloride (CTBS),...
Background: The highly transmissible coronavirus disease 2019 (COVID-19) has plagued the worldwide population with a continuous upward thrust of the death toll, which might be related to insufficient knowledge, attitudes, and behavioral (KAB) score, and public awareness. Objective: The current research sought to explore public awareness in terms of...
As there is a resurgence of interest in plants as promising sources of new active pharmaceutical constituents, the present study has been designed to establish the preliminary biological activities of Blumea clarkei Hook.f. leaves. Here, the crude methanol extract of the leaves along with its organic and aqueous soluble fractions were subjected to...
Malaria is a serious illness resulted from parasites that are communicated to people through the bites of infected female Anopheles mosquitoes. Malaria is still in a worrying trend, particularly in tropical and subtropical climates although it is curable and preventable. In spite of a noteworthy abetment in incidence and death rates caused by malar...
Dillenia pentagyna Roxb., a deciduous and medium sized tree, is an ethnobotanically important species of several Asian countries including Bangladesh, Srilanka, and India. Various parts of this endangered tree including leaf, bark, root etc. are used in folkloric medicine systems for a very long time. It is locally used in the treatment of pain, wo...
COVID-19, transmitted by SARS-CoV-2, is one of the most serious pandemic situations in the history of mankind, and has already infected a huge population across the globe. This horrendously contagious viral outbreak was first identified in China and within a very short time it affected the world's health, transport, economic, and academic sectors....
Caesalpinia digyna (Rottl.) (Family: Fabaceae) is well known for its numerous medicinal values against several human disorders including fever, senile pruritis, diarrhea, tuberculosis, tonic disorder, diabetes, etc. The current study is intended to investigate the in vivo antipyretic activity of the methanol extract of C. digyna leaves (MECD) and i...
Lygodium microphyllum Cav. (Family: Lygodiaceae) is a perennial, snake fern and an invasive weed in Florida and also known as old world climbing fern. This study is intended to evaluate the antipyretic, analgesic, anti-inflammatory, antidiarrheal and anthelmintic activity of methanol extract of Lygodium microphyllum Cav. leaves (MELM) by in vivo, i...
Piper nigrum L. also called black pepper is popular for its numerous uses. The present research is designed to investigate the pharmacological potential of methanol extract of Piper nigrum (MEPN). The antidepressant investigation was performed by using both in vivo forced swimming test (FST) and tail suspension test (TST) methods while the anxiolyt...
Tetrastigma leucostaphylum (Family: Vitaceae) is popular for its medicinal value in Bangladeshi tribal communities. This study aims to investigate several pharmacological values of methanol extract of T. leucostaphylum (METL). In vivo analgesic and anti-inflammatory researches have been implemented by using acetic acid-induced writhing and formalin...
Achyranthes aspera L. (Prickly Chaff flower) is an imperative Asian herb that has been known for numerous healing powers. The aim of this research is to investigate the pharmacological i.e., antidepressant and anxiolytic properties of the methanol extract of aerial part of A. aspera (MEAA) by in vivo and in silico approaches. Additionally, thrombol...
Colocasia affinis and Colocasia gigantea are two of commonly found species under Colocasia genus. Folkloric use of these plants ascertains their ethnopharmacological importance and these plants are eaten as vegetables in several regions all around the world while Colocasia gigantea has planted as an ornamental plant too. Phytochemical screening of...
As of July 21, the mean Rt and growth factor is 1.32 and 1.02, respectively.
Each phase of nation-wide lockdown has contributed to the decline of effective reproduction number (Rt) for Bangladesh by 28.44%, and 26.70%, respectively, implying moderate effectiveness of the epidemic response strategies.
The Rt of Bangladesh was below 1 for onl...
1. According to the Logistic curve fitting analysis, the inflection point of the COVID-19
pandemic has recently passed, which was approximately between May 28, 2020, to May 30,
2020.
2. It is estimated that the total number of confirmed cases will be around 187-193 thousand at
the end of the epidemic. We expect that the actual number will most like...
ABSTRACT: Tetrastigma leucostaphylum (Family: Vitaceae) is popular for its medicinal value in
Bangladeshi tribal communities. This study aims to investigate several pharmacological values of
methanol extract of T. leucostaphylum (METL). In vivo analgesic and anti-inflammatory researches have
been implemented by using acetic acid-induced writhing...
The study was intended to compare and evaluate the in vitro thrombolytic activity and in vivo anxiolytic activities of methanol extracts of Piper nigrum fruits (MEPNF) and Sesamum indicum seeds (MESIS). An in vitro thrombolytic activity was employed by investigating the clot lysis effect of MEPNF, MESIS, and their combinations. In vivo anxiolytic a...
Background Colocasia gigantea is locally named as kochu and also better known due to its various healing power. This research is to investigate the antidiarrheal, antimicrobial, and antioxidant possibilities of the methanol soluble extract of Colocasia gigantea.
Methods Antidiarrheal investigation was performed by using in vivo castor oil induced...
Objectives: Bauhinia scandens Linn,and Senna sophera has been locally known as monkey ladders and Kalkasunda in Bangladesh. They have several significant traditional uses as a source of the medicinal agent. This study is to implement the thrombolytic and cytotoxic activity of n-Hexane fraction of Bauhinia scandensstems and Senna sopherastems (NHBS,...
Cancer is one of the deadly diseases which is characterized by unchecked cell division or abnormal cell growth due to the incapability of cell cycle arrest. As the treatment for this is to kill the cancerous cells the main challenge for scientists is to direct the cell killing to cancerous cells while leaving the normal cells unharmed. Antibody-dru...
