Sadiman Kiykac Altinbas

Ankara Güven Hospital · Obstet & Gynecol

The aim was to investigate the association between bisphenol A (BPA), 25-hydroxy vitamin D [25(OH)D], and 1α,25 dihydroxy vitamin D [1,25(OH)2D] levels in the cord blood of newborn babies. BPA was measured by high pressure liquid chromatography (HPLC) and vitamin D levels by commercial ELISA or ECLIA kits. BPA and Vitamin D levels were grouped acco...

ÖZET Amaç: Üçüncü basamak bir doğum hastanesinde bir yılda gerçekleşen sezaryen doğumların Robson On Gruplu Sınıflandırma Sistemi kullanılarak analiz edilmesi amaçlanmıştır. Gereç ve Yöntem: 1 Ocak 2019 - 31 Aralık 2019 tarihleri arasında hastanemiz doğum salonuna kabul edilip, hastanemizde doğum yapmış olan ve herhangi bir obstetrik risk faktörü o...

Ovarian masses are relatively common conditions, with approximately 5%–10% of women requiring surgical treatment for an ovarian neoplasm during their lifetimes. A laparoscopic approach is the primary choice in surgical management of benign small ovarian masses; however, concerns remain about the feasibility and safety of laparoscopic surgery for la...

Objectives: To evaluate the feasibility and safety of laparoscopic surgery for large ovarian masses with benign features. Materials and methods: Women who underwent laparoscopic surgery for an ovarian mass with benign features between 2017 and 2019 at a tertiary referral center were included in the retrospective study. Based on the size of the o...

Aim: To develop a treatment and management algorithm for vulvar abscess. Methods: We evaluated the clinical findings and treatment modalities of patients hospitalized with vulvar abscess via a comprehensive literature review and a clinical study. Patients with a diagnosis of vulvar abscess (n = 28) between 2015 and 2019 in the gynecology clinic...

Aim: Aimed to evaluate the role of systemic inflammatory markers and Aspartate aminotransferase to Platelet Ratio Index (APRI) sore in predicting medical treatment failure in patients with Tubo-ovarian abscess (TOA). Materials and Methods: Patients (n=240) hospitalized with a diagnosis of TOA between August 2016 - October 2020 were included in the...

Aim: Aimed to evaluate the role of systemic inflammatory markers and Aspartate aminotransferase to Platelet Ratio Index (APRI) sore in predicting medical treatment failure in patients with Tubo-ovarian abscess (TOA). Materials and Methods: Patients (n=240) hospitalized with a diagnosis of TOA between August 2016 - October 2020 were included in the...

Importance: Currently, apical prolapse is diagnosed via assessing the levels of C and D points in the pelvic organ prolapse quantification (POP-Q) system. However, it is not yet known whether the other components of this system are useful for diagnosing apical prolapse and its symptoms. Objective: The aim of the study was to evaluate the associa...

This study aims to compare the uterine body longitudinal axis, uterine body transverse axis, uterine cervix longitudinal axis and anterior cervical axis angle measured ultrasonographically between women with pelvic inflammatory disease (PID) and healthy controls. Women aged 18–45 years with PID and healthy controls were included in the study. Demog...

Objective: We aimed to determine the effect of dienogest on cyst volume, symptoms, and quality of life in patients with endometrioma. Method: This prospective cohort study included 37 patients diagnosed with endometrioma and planned for medical treatment. Subjects were treated with a 3-month oral dose of dienogest 2 mg/day. Pre-treatment and pos...

Objectives: The study aimed to determine the awareness of emergency contraception (EC) and knowledge of its use as well as the unplanned pregnancy rate among women in the immediate postpartum period in Ankara, Turkey's second largest city. Methods: Interviews were carried out among 1955 women on their first or second day postpartum. The intervie...

Postoperative adhesions can cause serious complications, including intestinal obstruction, chronic abdominopelvic pain, and infertility in women. Here we investigate the effects of disulfiram on the postoperative adhesion model. Female Wistar rats were used (n = 72). The animals were separated into six groups (12 rats per group): group 1 (control),...

Aim: To evaluate if the neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) could be used to diagnose adnexal torsion. Methods: A retrospective study reviewed medical records of women who underwent surgery due to an adnexal mass between January 2012 and December 2017 at a tertiary referral center in Turkey. According...

The aim of this study was to evaluate the effects of tubal ligation (TL) via modified Pomeroy method on ovarian reserve and to determine the role of curcumin (Curcuma longa [Indian saffron]) against ovarian reserve decrement after TL. Forty-eight albino Wistar rats were randomly divided into four groups: (1) Control group: a sham operation was perf...

Pelvic organ prolapse (POP) is a significant healthcare problem, affecting millions of women throughout the world. POP is defined as the descent of one or more pelvic organs as a result of vaginal support defects of the anterior, posterior, or apical vaginal vault which might include uterine prolapse. The lifetime risk of women to undergo a single...

Endometrial hyperplasia is a process of endometrial proliferation that results in a thickening of the endometrial tissue. Melatonin might be able to change the pathophysiological process and prognosis into a positive way that might prevent and heal endometrial hyperplasia, which is the first stage of endometrial cancer. For this perspective, we tri...

Various congenital anomalies of the female tract such as agenesis, vertical or lateral fusion failure, and canalization failure occur when the normal development of the Müllerian duct disrupts in any stage of developmental milestones. A cavitated non-communicating rudimentary horn is reported in about 20%-25% of women with unicornuate uterus. A 36-...

After the SARS‑CoV‑2 virus causing COVID-19 infection was first detected in Wuhan, China in December 2019, the number of infected people rapidly increased, and the World Health Organization declared the infection as a pandemic on March 11, 2020. Our war against the COVID–19 infection, which threatens the whole world and humanity, is continuing. Whe...

A global public health problem with a high rate spread and transmission, Coronavirus outbreak has become the most talked-about matter throughout the world. We are severely affected by the nations with vast numbers of deaths; it was hard to predict such a colossal pandemic with terrifying consequences. Elective surgeries are limited, but situations...

Uterine manipulators are used for diagnostic assessment or surgical interventions in most of the advanced laparoscopyassisted gynecological procedures. They ensure the mobilization of the uterus making it possible for the operator to access anatomical structures (vascular pedicle, ligament, vaginal wall, etc.). The uterine manipulators are useful a...

Objective: To investigate the correlation between sonographic, hysteroscopic, and pathological findings in postmenopausal asymptomatic patients with sonographically thickened endometrium. Methods: The records of postmenopausal patients who attended the Menopause Outpatient Clinic of a tertiary women's hospital in Ankara, Turkey between January 1...

Pelvic organ prolapse is a highly prevalent condition, and the lifetime risk of requiring surgical treatment could be as high as 11% [1, 2]. Among patients who wish to retain their reproductive capacity or retain their uterus, uterine conservation can be offered. A variety of surgical techniques including vaginal, abdominal, and laparoscopic (conve...

Tuboovarian abscesses (TOAs) are considered to be a problem during a woman's reproductive ages, and the diagnosis appears to be infrequent in postmenopausal women. It has been reported that 34% of patients hospitalized with a diagnosis of acute genital tract infections in reproductive ages develop TOA. It seems to be a serious problem to be solved...

We present a case of a symptomatic perforation by an intrauterine device (IUD) into ileum resulted as a tubo-ovarian abscess. A 38-year old patient, who received TCu 380A in approximately 7 years ago, presented at the outpatient clinic with tubo-ovarian abscess. The patient received a 12-day course of antibiotic regimen intravenously. Clinical find...

Objectives To investigate factors associated with the response to ovarian stimulation in patients with polycystic ovary syndrome. Methods The records of patients with polycystic ovary syndrome and infertility who underwent ovulation induction with clomiphene citrate were reviwed between January 2011 and December 2014 in Etlik Zübeyde Hanim Women’s...

Aim: Today laparoscopy is the gold standard approach to treating benign adnexal masses. The maximum size of the ovarian mass that can be operated on using laparoscopy, as opposed to laparotomy, is unclear. In this study we aimed to evaluate the relationship between the adnexal mass size and the surgery type. Material and Method: 158 women who were...

Objective: Endometriosis is a chronic inflammatory disease pathologically defined as the presence of endometrial-like tissue outside the uterine cavity. It is one of the most important diseases affecting women of reproductive age. The process of endometriotic implant growth is mediated by many complex interactions of immunologic, hormonal, genetic,...

Objective: The aim of the presented study is to investigate the impact of progesterone change in the late follicular phase on the pregnancy rates of both agonist and antagonist protocols in normoresponders. Study design: A total of 201 normoresponder patients, who underwent embryo transfer were consecutively selected. 118 patients were stimulate...

The aim of this study was to investigate the effect of clarithromycin in rat endometriosis and its association with matrix metalloproteinase-9 (MMP-9) expression. After surgical induction of endometriosis, 27 rats were randomised into three groups. Size of endometriotic implants were evalutated and rats in group I (n = 9) were given 100 mg/kg/day o...

Patients' perception of minimally invasive gynecologic surgical procedures affects their decision to undergo such procedures and their expectations after surgery. A questionnaire was distributed to patients referred for minimally invasive gynecologic surgical procedures to assess for perceptions and understanding. A total of 103 patients agreed to...

The aim of this study was to investigate the possible therapeutic effects of Doxycycline (Dox) on endometriotic lesions in an experimental rat model. Thirty-seven female Wistar albino rats with surgically induced endometriosis were randomized and divided into four groups. The rats were administered 5 mg/kg/day oral Dox in Group 1 (low-dose Dox grou...

Background To compare the knowledge and preference of preconceptional contraception to future postpartum contraceptive method choice in high-risk pregnancies. Research question Does a high-risk pregnancy condition affect future postpartum contraceptive method choice? Method Women hospitalised at the High Risk Pregnancy unit of a tertiary research...

Our aim was to investigate the use of a balloon catheter device in comparison with metal cannula for hysterosalpingography (HSG) in terms of patient comfort. A total of 168 patients were randomised for HSG either with a balloon catheter (n = 83) or metal cannula (n = 85). Scores of pelvic pain during insertion of the devices, injection of the contr...

Background: The association between blood types and ovarian reserve is investigated in this study. Materials and methods: As an index of ovarian reserve, women with a follicle stimulat- ing hormone (FSH) level of ≥10 mIU/ml in the early follicular phase were designated as having diminished ovarian reserve. In this prospective study, early follic...

We assessed the impact of pain, dysmenorrhoea and dyspareunia on the quality of life among Turkish fertile women with severe endometriosis. A total of 33 patients with histopathologically diagnosed severe endometriosis (Stage IV, revised criteria of the American Fertility Society (rAFS score) were enrolled into the study. Patients reported chronic...

Aim: To determine factors associated with face presentation of term fetuses delivered. Methods: Of 34,480 consecutive, term deliveries of uncomplicated pregnancies within a 3-year period, all live, singleton term fetuses with cephalic presentation in which no lethal anomalies occurred that were diagnosed with a face presentation were studied. Fa...

The objective of this study was to examine perioperative outcomes, including complication rates, of conventional laparoscopy (CL) versus robotic-assisted laparoscopy (RALS) in the evaluation and management of early, advanced, and recurrent ovarian, fallopian tube, and peritoneal cancer. This is a retrospective analysis of a prospectively maintained...

A 13-year-old patient with a complaint of worsening lower abdominal pain during the past 4 months was admitted to the emergency department. An abdominopelvic ultrasound scan revealed a distended uterocervical cavity suggestive of hematometrocolpos. Imperforate hymen was observed on examination of the external genitalia. MRI scan revealed an air-flu...

Our aim was to evaluate the value of surgery, mainly laparoscopy in the diagnosis of the location of extrauterine lost intrauterine devices (IUCDs) and their removal. The diagnosis and management of 18 patients with extrauterine lost IUCDs between 2007 and 2011, were recruited in this study. Women whose lost IUCDs were removed by conventional metho...

Objective: To evaluate maternal-fetal outcomes of the pregnancies complicated by intrahepatic cholestasis and to discuss the pregnancy management. Material and Methods: Medical records of 33 patients diagnosed as intrahepatic cholestasis of pregnancy between January 2006 and December 2009 were retrospectively evaluated in this study. Results: The m...

Objective: To determine the contraceptive methods and postpartum contraceptive choices in patients with current unintended pregnancies. Material and Method: The study was conducted with pregnant women applied to antenatal outpatient clinic via face-to-face interviews between January 2009-May 2011. Demographic data, education levels, monthly income,...

Growing teratoma syndrome (GTS) is a rare complication of malignant ovarian germ cell tumors. A 52-year old woman was admitted to our Gynecological Oncology Department with metastatic multiple abdominal masses. Her initial gynecological history presented an immature teratoma of the ovary 3 years previously, and she underwent total abdominal hystere...

Abstract Objective: To evaluate short-term effects of closure versus non-closure of the parietal peritoneum at caesarean section. Methods: A randomized controlled study of women undergoing caesarean section was conducted at the obstetrics department of a research and education hospital between October 2010 and May 2011. Patients were randomly assig...

Aim: We aimed to evaluate the role of first trimester serum uric acide level to predict glucose intolerance in pregnancy. Method: Patients who admitted to Fatih University Faculty of Medicine for routine antenatal follow-up at first trimester were included in the study. Serum uric acid levels were measured at first trimester. Glucose challenge test...

Current published data makes clear the relationship between genital human papillomavirus (HPV) infection and cervical cancer. Although there is an opportunity for screening programs that could obviate the disease, cervical cancer still remains the second most common cancer among women worldwide. The subtypes HPV 16 and 18 affect the anogenital trac...

Objective: To compare cord blood oxidative stress markers (OSM) between intrauterine small fetuses with high umbilical artery (UA) Doppler indices and normal indices. Methods: Forty women who had oligohydramnios and intrauterine growth-restricted fetuses with abnormal (n = 20, group I) or normal Doppler indices (n = 20, group II) were included....

Aim: The present study aimed to compare Troponin T (Tp T) levels of infants born with meconium stained amniotic fluid (MSAF) to those with clear amniotic fluid. Study design: Case-control study Subjects: Thirty-five women who had delivery complicated by MSAF between 37 and 41weeks of gestation were defined as the study group and women with hea...

Objective: The aim of this study was to compare cord blood S100B levels and cord blood gas parameters of term infants with meconium-stained amniotic fluid (MSAF) to those infants with clear amniotic fluid. Methods: Term pregnant women at an active phase of labor and having MSAF were defined as the study group (n = 35) and pregnant women with clear...

Even though the 50 g oral glucose challenge test (GCT) is the most commonly used screening modality for gestational diabetes mellitus (GDM), no consensus for the diagnostic approach is available to patients with a markedly elevated GCT result. We aimed to evaluate the diagnostic utility of markedly elevated GCT results and the impact of age using t...

To determine the incidence, indications and the risk factors of emergency peripartum hysterectomy (EPH). We analyzed retrospectively 30 cases of emergency peripartum hysterectomy performed at the Obstetrics Department of a tertiary, research and education hospital between the years of 2006 and 2010. Demographic, medical and clinical data of the pat...

To evaluate the efficacy of tertiary cytoreduction (TCR) on survival and to determine prognostic factors which may influence surgical and survival outcome. Twenty-three consecutive patients who had recurrent platinum-sensitive epithelial ovarian cancer and underwent TCR between January 1999 and January 2011 were evaluated. Factors which impact on T...

Infertility is defined as the time of one year of unprotected intercourse without conception and affects approximately 15% of the couples. Data available over the years reveal that pathology is found among 55% of cases in women, 35% of cases in men and the remaining 10% of cases are defined as unexplained infertility. Male infertility is commonly d...

The aim of this study was to determine the prevalence of gestational diabetes mellitus (GDM) and gestational impaired glucose tolerance (GIGT) in adolescent pregnancies, associated risk factors, and pregnancy complications. Retrospective study. Community-based teaching hospital. Results of 1653 pregnant women age ≤ 19 years in 2005-2007 were review...

To compare efficacy of the levonorgestrel-releasing intrauterine system (LNG-IUS; Mirena) with depot GnRH analogue (GnRH-a; gosareline acetate; Zoladex) on endometriosis-related chronic pelvic pain (CPP) in patients with severe endometriosis during 12 months. Prospective, randomized, controlled study. The reproductive endocrinology unit of a tertia...

We report a case of ovarian cystic teratoma with an important growth during pregnancy and the sonographic appearance of intracystic multiple, mobile, polygonal structures called intracystic "fat balls." Due to the rapid growth of the lesion, which exceeded 15 cm in diameter, a right oophorectomy was performed. Histopathologic diagnosis confirmed th...

Universal neonatal hearing screening programmes are encouraged to define and manage hearing loss in early ages of life. The aim of this study is to introduce our 14-month three-step hearing screening programme results with 16 975 births in Turkey. In healthy neonates, Transient Evoked Otoacoustic Emission (TEOAE) is served as the initial screening...

Patients with history of gestational diabetes (GDM) are at high risk for developing diabetes mellitus (DM) after pregnancy. This study investigates the rate of GDM patients who received screening and the prevalence of DM in the early post-partum period. This study included 78 patients diagnosed and treated for GDM between January 2005 and December...

We report three maternal deaths which might be in possible association with the use of intravaginal dinoprostone for cervical ripening and induction of labor. All cases occurred at our institution between January 2006 and December 2007. Uterine atony and profuse bleeding followed by disseminated intravascular coagulation (DIC), characterized by sev...

To assess whether early repair of episiotomy before expulsion of placenta affects postpartum blood loss. Patients who had normal vaginal delivery with episiotomy were enrolled in the study. One hundred and twenty who were randomly allocated to either episiotomy repair before (Group 1: 60) or after spontaneous placental expulsion (Group 2: 60) had m...

Objective: The aim of this study was to compare the pregnancy outcomes in women aged 40 years and older to that of women 20 to 29 years old after 20 weeks of gestation. Materials and Methods: In this cross-sectional retrospective study, 153 pregnant women at least 40 years of age consisted the study group while 156 pregnant women aged between 20 an...