Sachith Munasinghe- Doctor of Medicine
- Post Doctoral Fellow at Emory University
Sachith Munasinghe
- Doctor of Medicine
- Post Doctoral Fellow at Emory University
About
5
Publications
205
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3
Citations
Introduction
Skills and Expertise
Current institution
Education
November 2015 - May 2022
Publications
Publications (5)
Crohn's disease (CD) involves a complex intestinal microenvironment driven by chronic inflammation. While single-cell RNA sequencing has provided valuable insights into this biology, the spatial context is lost during single-cell preparation of mucosal biopsies. To deepen our understanding of the distinct inflammatory signatures of CD and overcome...
Objectives
Defecation disorders are a common pediatric problem and bowel frequency is crucial in identifying them. The aim of this analysis is to define normal bowel frequencies in healthy children ranging from newborns to adolescents.
Methods
A literature search was conducted using MEDLINE, SCOPUS, EMBASE, Cochrane Library, and Web of Science fro...
Background
Evaluation of hypercalcaemia in a patient with chronic kidney disease (CKD) is challenging, especially in low-resource settings. Hormone assays should be interpreted with caution as CKD affects both parathyroid hormone (PTH) and vitamin D. Therapies such as bisphosphonates are contraindicated in CKD, while fluid resuscitation can lead to...
Objective: Normal bowel frequency is considered as the key indicator of bowel health. We conducted a meta-analysis with a meta-re- gression to assess the normal bowel frequency of healthy children. We aimed to create a normative data set for bowel frequency for children from birth to 18 years using the existing literature.
Methods: A literature sea...
The COVID-19 pandemic caused by the SARS-CoV-2 virus has infected millions and overburdened the healthcare infrastructure globally. Recent studies show that the endothelial dysfunction caused by the virus contributes to its high morbidity and mortality. A parameter that can identify patients who will develop complications early will be valuable in...
