Sachendra Pratap Singh

Sachendra Pratap Singh
King George's Medical University | CSM · Department of Cardiology

PhD (Persuing)

About

8
Publications
1,824
Reads
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38
Citations
Additional affiliations
September 2019 - May 2020
King George's Medical University
Position
  • Research Assistant
April 2019 - August 2019
Center of Biomedical Research
Position
  • Fellow
January 2016 - March 2019
Era's Lucknow Medical College and Hospital
Position
  • Research Assistant
Description
  • Experienced Research Assistant with a demonstrated history of working in the hospital & health care industry. Skilled in Real-Time Polymerase Chain Reaction (qPCR), Microsoft Word, C++, SDS-PAGE, and Public Speaking.
Education
July 2012 - August 2014
Bundelkhand University
Field of study
  • Biotechnology
July 2009 - August 2012
M.J.P. Rohilkhand University
Field of study
  • Zoology, Chemistry

Publications

Publications (8)
Article
Full-text available
Background: Endothelial nitric oxide synthase (eNOS) and potassium voltage-gated channel subfamily J member 11 (KCNJ11) could be the candidate genes for coronary artery disease (CAD). This study investigated the relationship of the eNOS (rs1799983) and KCNJ11 (rs5219) polymorphisms with the presence and severity of CAD in the North Indian populati...
Article
Cardiac hypertrophy (CH) is an augmentation of either the right ventricular or the left ventricular mass in order to compensate for the increase of work load on the heart. Metabolic abnormalities lead to histological changes of cardiac myocytes and turn into CH. The molecular mechanisms that lead to initiate CH have been of widespread concern, henc...
Article
Full-text available
ABSTRACT VOL.5 NO.2 There are about 40% of patients with type 1 and type 2 diabetes will develop diabetic nephropathy (DN), resulting in chronic kidney disease and potential organ failure. During the progression and development of DN, chronic elevated blood glucose (hyperglycaemia) together with glomerular hypertension leads to renal inflammation...
Article
Full-text available
Background Type 2 diabetes mellitus (T2DM) is a global major health problem resulting from interaction of environmental and genetic factors, examples of the latter being KCNJ11 (coding for part of the ATP-sensitive potassium channel) and SDF-1β (coding for chemokine CXCL12). Our case-control study was conducted to assess whether recessive, dominant...
Article
Full-text available
Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by polygenic hyperglycemia caused by insulin secretion or insulin resistance. Several environmental factors and genetics interact to increase the risk of developing type 2 diabetes and its complications. Among the various factors associated with genetic T2DM polymorphism of the s...
Article
Full-text available
Diabetic nephropathy accounts for the most serious microvascular complication of diabetes mellitus. It is suggested that the prevalence of diabetic nephropathy will continue to increase in future pretense a major challenge to the healthcare system resulting in increased morbidity and mortality. It occurs as a result of interaction between both gene...

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