Sabrina Khan

Sabrina Khan
California State University, Sacramento | CSUS · Department of Psychology

About

34
Publications
3,347
Reads
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558
Citations
Citations since 2016
33 Research Items
546 Citations
2016201720182019202020212022050100150
2016201720182019202020212022050100150
2016201720182019202020212022050100150
2016201720182019202020212022050100150

Publications

Publications (34)
Article
Full-text available
Plain Language Summary Clasts are loose fragments produced by the breakdown of rock, which can be transported and reshaped by forces like water, wind and gravity. Clast shape, size, and texture are useful indicators of the clast's origin and the forces that have transported and modified it over time. The Glen Torridon region of Gale crater, the fie...
Article
Full-text available
Gale crater, the field site for NASA's Mars Science Laboratory Curiosity rover, contains a diverse and extensive record of aeolian deposition and erosion. This study focuses on a series of regularly spaced, curvilinear, and sometimes branching bedrock ridges that occur within the Glen Torridon region on the lower northwest flank of Aeolis Mons, the...
Article
Full-text available
In order to determine the relationship between socioeconomic deprivation and nonalcoholic fatty liver disease (NAFLD)/nonalcoholic steatohepatitis (NASH), we retrospectively reviewed the electronic medical records of 1,430 patients in a large tertiary health care network in New York. These patients underwent liver biopsy over a 10-year period and w...
Article
Full-text available
Migraine is a disabling primary headache disorder that directly affects more than one billion people worldwide. Despite its widespread prevalence, migraine remains under-diagnosed and under-treated. To support clinical decision-making, we convened a European panel of experts to develop a ten-step approach to the diagnosis and management of migraine...
Article
Full-text available
Off-peak delivery (OPD) is the delivery of goods during the evening and overnight hours. This strategy has the potential to alleviate peak period congestion, improve efficiency of delivery firms, and reduce emissions. This paper investigates benefits and challenges of a pilot OPD program in the Region of Peel, with the goal of informing potential b...
Article
Purpose This paper aims to examine the effects of high-performance work practices (HPWPs) (participation, training and compensation) on nurses’ job performance (task and contextual) through the mediating role of job satisfaction. As nurses form the bulk of health-care professionals, their performance at work is crucial in determining patient satisf...
Article
Motivation is exceptionally crucial in influencing the quality of health care work outcomes. In view of the mounting challenges and stressful work environment faced by nurses, social support has been identified as an essential resource that helps promote their work motivation. The central aim of this study is to explore 3 forms of social support (p...
Article
Full-text available
Introduction: To analyze the impact of acute-on-chronic liver failure (ACLF) immediately before liver transplantation (LT) on short-term kidney function. Methods: In this retrospective study, we included 416 of 687 consecutive patients who had an estimated glomerular filtration rates (eGFRs) at 3-month post-LT. We compared the non-ACLF (N = 356)...
Conference Paper
Background: We initiated the systematic NCI-ALMANAC in vitro combination drug screen of FDA-approved anticancer drugs in the NCI-60 tumor cell line panel to explore novel and effective drug combinations (Holbeck et al., Cancer Res 2017). In this screen and in preclinical xenograft models, the BCR-ABL kinase inhibitor nilotinib demonstrated greater-...
Conference Paper
Background: The NCI ALMANAC study carried out a systemic drug screen with 2.8 million dose combinations to identify drug pairs with greater than additive activity. This was followed by patient-derived xenograft models, which demonstrated that the combination of the proteasome inhibitor bortezomib and the nucleoside analog clofarabine was highly act...
Article
Background: We initiated the systematic NCI-ALMANAC in vitro combination drug screen of FDA-approved anticancer drugs in the NCI-60 tumor cell line panel to explore novel and effective drug combinations (Holbeck et al., Cancer Res 2017). In this screen and in preclinical xenograft models, the BCR-ABL kinase inhibitor nilotinib demonstrated greater-...
Conference Paper
Background: The PI3K pathway is frequently dysregulated in cancer, promoting tumorigenesis by facilitating aberrant cell growth, blocking apoptotic signaling, and suppressing immune surveillance in the tumor microenvironment (TME). The TME contains regulatory immune cells such as FOXP3+ regulatory T cells (Tregs), myeloid-derived suppressor cells,...
Conference Paper
Introduction: Treatment with rhIL-15 has been repted to significantly increase levels of circulating CD8+ T cells, NK cells, and inflammaty cytokines. In vivo administration of rhIL-15 with immune checkpoints inhibits of CTLA-4 and PD-L1 resulted in increased tum antigen-specific CD8+ T-cells, enhanced CD8+ tum lytic activity, and improved mouse su...
Conference Paper
Introduction: Treatment with rhIL-15 has been repted to significantly increase levels of circulating CD8+ T cells, NK cells, and inflammaty cytokines. In vivo administration of rhIL-15 with immune checkpoints inhibits of CTLA-4 and PD-L1 resulted in increased tum antigen-specific CD8+ T-cells, enhanced CD8+ tum lytic activity, and improved mouse su...
Article
Introduction: The National Cancer Institute-Molecular Analysis for Therapy Choice (NCI-MATCH) is a multicenter phase II tissue agnostic trial with 39 treatment arms, that matches a targeted drug to an actionable genetic alteration identified by next-generation sequencing (NGS). It is unique in use of a bioinformatics tool MATCHBox to make patient t...
Article
TPS3148 Background: The nucleoside analog 5-aza-4’-thio-2’-deoxycytidine (Aza-TdC) inhibits DNA methyltransferase 1 (DNMT1), a methyltransferase involved in methylation-mediated silencing of tumor suppressor genes. Attenuation of DNA methylation via DNMT1 inhibitors results in reactivation of silenced tumor suppressor genes and can lead to tumor gr...
Article
3067 Background: M6620 (M), a potent ATR inhibitor, has synergistic activity with cisplatin (C) in multiple preclinical models, resulting in DNA damage and antitumor activity. We hypothesize that inhibition of both homologous recombination and base excision repair through the combination of M6620 and veliparib (V, a potent inhibitor of PARP1/2) wou...
Article
Full-text available
Background: The three primary headaches, tension-type headache, migraine and cluster headache, occur in both genders, but all seem to have a sex-specific prevalence. These gender differences suggest that both male and female sex hormones could have an influence on the course of primary headaches. This review aims to summarise the most relevant and...
Book
Full-text available
The principle of impartiality is at the core of humanitarian action: It should be provided based on need alone. But how can humanitarian organisations realise this in escalated conflicts? Given the fact of “forgotten crises” – does this principle also apply on the global level? And how are impartiality and the growing role of local actors in humani...
Book
Full-text available
Das Prinzip der Unparteilichkeit macht den Kern der humanitären Hilfe aus: Sie soll allein nach dem Maß der Not geleistet werden. Aber wie könne humanitäre Hilfsorganisationen dies in eskalierenden Konflikten leisten? Gilt das Prinzip angesichts „vergessener Krisen“ auch im globalen Maßstab? Und wie hängen Unparteilichkeit und die immer wichtigere...
Article
Purpose: Loss of colonization resistance within the gastrointestinal microbiome facilitates the expansion of pathogens and has been associated with death and infection in select populations. We tested whether gut microbiome features at the time of intensive care unit (ICU) admission predict death or infection. Methods: This was a prospective coh...
Article
Lusskin SI, Khan SJ, Ernst C, Habib S, Fersh ME, Albertini ES. Pharmacotherapy for Perinatal Depression. Clin Obstet Gynecol. 2018. doi:10.1097/grf.0000000000000365 Perinatal depression is associated with serious risks for the mother, baby, and family. When considering treating perinatal depression with a drug indicated for the treatment of depres...
Article
Perinatal depression is associated with serious risks for the mother, baby, and family. When considering treating perinatal depression with a drug indicated for the treatment of depression, the major concerns are whether the drug increases the risks of teratogenicity, pregnancy complications, poor neonatal adaptation, or neurodevelopmental disorder...
Article
Turnover poses a serious threat in healthcare settings. The scarcity of healthcare professionals and particularly nurses is highlighted as one of the biggest obstacles to achieving health system efficiency and effectiveness. As such, healthcare administrators need to search for ways to retain qualified and competent nurses. This study provides a fr...
Article
Ceftazidime-avibactam (CAZ/AVI) is a promising novel treatment for carbapenem-resistant Enterobacteriaceae (CRE). Despite improved treatment outcomes compared to aminoglycoside- and colistin-based regimens, rapid evolution of CAZ/AVI resistance during treatment has previously been reported in Klebsiella pneumoniae ST258 blaKPC-3 harboring isolates....
Article
Full-text available
Pregnancy and postpartum represent times of increased vulnerability for women with bipolar disorder, yet this condition remains under-diagnosed and under-treated. As 50 % of pregnancies are unplanned, the risks associated with the illness and the potential risks associated with treatment should be considered when a woman of reproductive age first p...
Article
Frontal fibrosing alopecia (FFA) is a scarring alopecia, now an accepted subset variant of lichen planopilaris (LPP). Its occurrence in males is rare, with only nine cases reported to date. We describe a case of FFA in a male in association with lupus erythematosus. Multiple biopsies from the scalp, eyebrow and arm showed features consistent with L...

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