Sabrina Kali

French research agency on infectious and emerging diseases/ANRS | MIE · Clinical Research

ABMA and its analogue DABMA are two molecules of the adamantane family known to perturbate the endosomal pathway and to inhibit cell infection by several RNA and DNA viruses. Their activity against Rabies Virus (RABV) infection has already been demonstrated in vitro. (Wu et al., 2017, 2019). Here, we describe in more details their mechanism of acti...

Arthropod-borne flaviviruses are human pathogens of global medical importance, against which no effective small molecule-based antiviral therapy has currently been reported. Arbidol (umifenovir) is a broad-spectrum antiviral compound approved in Russia and China for prophylaxis and treatment of influenza. This compound shows activities against nume...

Arthropod-borne flaviviruses represent human pathogens of global medical importance, against which no effective small molecule-based antiviral therapy is currently available. Arbidol (umifenovir) is a broad spectrum antiviral compound approved in Russia and China for prophylaxis and treatment of influenza. This compound showed activity against nume...

Intracellular pathogenic microorganisms and toxins exploit host cell mechanisms to enter, exert their deleterious effects as well as hijack host nutrition for their development. A potential approach to treat multiple pathogen infections and that should not induce drug resistance is the use of small molecules that target host components. We identifi...

In common cold, cough or any other allergic reactions, the use of anti-histaminic medicines is common. If these persons have already on any medication they unknowingly become victims of the drug-drug interactions and the condition will become still pathetic. An attempt has been made to list the interactions of antihistamines with commonly used medi...

Hemorrhoids are one of the most common causes of anal pathology. Subsequently, hemorrhoids are blamed for virtually any anorectal complaint by patients and medical professionals. Confusion often arises because the term "hemorrhoid" has been used to refer toboth normal anatomical structures and pathological structures. This article is concerned with...

Adducts of Cu(OOCR) 2 (where R = 2-, 3- or 4-ClC 6H4) with saturated substituted piperazines of the type Cu(OOCR) 2(L-L) n (where n = 0.5 or 1 and L-L = 1-methylpiperazine (1-MePipz), 1,4-dimethylpiperazine (1,4-Me 2Pipz), 2,6-dimethylpiperazine (2,6-Me 2Pipz) and 1-phenylpiperazine (1-PhPipz)) have been prepared and characterized by elemental anal...

The present study was aimed at evaluating trace element changes and diagnostic role of magnesium levels in hair of migraine patients during interictal period. We assessed trace element levels in hair of migraine patients (n = 40) and control subjects (n = 21). In the group of migraineurs, magnesium (p < 0.05), zinc (p < 0.05), and copper (p < 0.001...

Recurrent syncope, malignant ventricular arrhythmias, and sudden death are complications of the long QT syndrome (LQTS). Two well-known syndromes with long QT intervals are known. The Jervell and Lange-Nielsen syndrome (JLNS) is characterized by prolongation of the QT interval, deafness, and autosomal-recessive inheritance, and the Romano-Ward synd...

In this study, hair magnesium (Mg), zinc (Zn), copper (Cu), and manganese (Mn) levels, and serum Zn and Mg levels were measured by atomic absorption spectrophotometer in patients with epilepsy (n = 33) and healthy subjects (n = 21), and results obtained were statistically compared. The mean hair Cu, Mg, and Zn levels of epileptic patients were sign...

Klinigimizde siddetli sol yarım basağrısı, geçici motor afazi ve sol hemiparezi atakları ile

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