Sabeeha Shafi

• Professor (Associate) at University of Kashmir

Inflammation is a cornerstone in numerous pathological conditions, prompting a growing hobby in exploring natural compounds as capability modulators of inflammatory responses. This complete evaluation synthesizes the current information on the tricky interaction between irritation and natural compounds, elucidating their mechanisms of action, numer...

The management of metabolic disorder-diabetes mellitus is an important criterion for its pharmacotherapy [1]. In preventing the progress of the disease, medicinal plants play very important role. Due to the side effects associated with the oral hypoglycaemic agents, currently, there is growing interest in herbal remedies for the management of diabe...

Inflammation is considered an overwhelming burden to the healthcare status and is associated with a significant number of diseases such as cancer, chronic lower respiratory disease, inflammatory bowel diseases, diabetes, asthma, osteoporosis, nephritis, etc. Diabetes mellitus is accompanied by long-lasting damage, dysfunction, and failure of differ...

Background: Apoptosis is a normal physiological phenomenon that plays a pivotal role during embryonic development, retention of tissue homeostasis and pathology. The experimental investigation of apoptotic processes is still challenging and routinely based on the assessment of molecular events like chromatin fragmentation and caspase enzyme activit...

Diabetes is a major global health threat to the human health as the prevalence has rapidly increased over the past four decades. The costs of diabetes include both direct costs from medical care as well as indirect costs incurred through loss of productivity or earnings, both of which are important contributors to the global economic burden. Global...

Communicable Diseases are caused by various opportunistic pathogenic micro-organisms that pose a serious health threat to the health of human beings. The contagious diseases are spread by various pathogenic micro-organisms like bacteria, viruses, fungi, bacteria or Protozoa through various mediums like air, blood, feces or through other blood fluid...

Bunium persicum(BOISS)B.Fedtsch belonging to family Apiaceae is native to the region of the limited zones of the West Asia, Kherman and grows to the areas of North Khorasan and Kheraman, East of the Zagros range to Bandar Abbaas and south area of the Albroz range in Iran. It is also found in North western parts of Himalayas. Bunium persicum is foun...

Eriobotrya japonica locally called as loquat in Kashmir has been studied in various parts of the world but little work has been reported on Kashmiri loquat. The chemical nature of fruits and vegetables offers a great diversity of biological properties and plays an important role in the field of pharmacology. There is a quest for newer drugs with fe...

Objective: The main aim of the present study was to evaluate the phytochemical constituents, and renal effects of the ethanolic extract of the fruits and seeds of Eriobotrya japonica, commonly called as Loquat in Kashmir. So far, no such study was carried in Kashmir.Methods: Phytochemical screening involved the standard procedures. Diabetes was ind...

The main objective of the study was to evaluate the in vitro anti-oxidant parameters for the study of memory enhancing activity of Mentha arvensis Linn closely related to Alzheimers disease. Mentha arvensisLinn is a plant commonly known as Pudina.It is used in our daily cuisines in India. The study included the aerial parts of Mentha arvensis belon...

The present study was undertaken to evaluate the phytochemical constituents, renal and hypoglycaemic effects of the ethanolic extract of the fruits of Eriobotrya japonica, commonly called as Loquat in Kashmir. The renal effects were determined by estimating the kidney function tests i.e., serum urea levels, serum creatinine levels, serum total prot...

Portulaca oleracea commonly called as Nunar in Kashmiri, Common Purslane in English and Lunia in Hindi is a weed that is cosmopolitan in nature and grows in warm temperate, tropical and subtropical regions of the world. Many chemical constituents have been isolated from this plant which has shown a number of pharmacological activities of this plant...

The hydro-alcoholic extract of fruits of Eriobotrya japonica was evaluated for its toxicity on hepatic and hematological parameters in swiss albino mice. Animals of either sex were treated with different doses of the extract for its acute toxicity tests. The doses taken were 500,1000,1500,2000 mg/kg. In this LD50 was calculated. After finding the L...

Objective: To evaluate the toxicity (acute and sub-acute) of hydro-alcoholic extract of Portulaca oleracea (whole plant) in Swiss albino mice. Methods: Acute oral toxicity study was carried out as per OECD 423 guidelines. The doses that were taken are 500 mg/kg, 1000 mg/kg,1500 mg/kg and 2000 mg/kg b. w. These doses were given once daily. The anima...

Angiotensin converting enzyme (ACE) inhibitors are an important class of antihypertensive drugs which have been used in the treatment of cardiovascular diseases where hypertension is the main risk factor. In hypertensive patients, it has been observed that there is formation of atherosclerotic plaques.Circulating and local renin angiotensin system...

Diabetes is a metabolic disorder characterized by hyperglycemia, hypertriglyceridemia and hypercholesterolemia, resulting from defects in insulin secretion or action or both. India is known as the diabetic capital of the world. The study of plants having antihyperglycemic and hypolipidemic activities gives a new approach in the treatment of diabete...

In recent years, focus on plant research has increased all over the world and a large body of evidence has been collected to show immense potential of medicinal plants used in various traditional system. Eriobotrya japonica is also found to possess significant medicinal and pharmacological activities against various diseases and disorders. The pres...

Objective: To carry out a preliminary phytochemical screening, acute oral toxicity and hypoglycemic study of 50% ethanolic extract of Portulaca oleracea (whole plant) in swiss albino mice. Methods: Preliminary phytochemical screening was done as per standard procedures. Acute oral toxicity study was conducted as per OECD 423 guidelines, and method...

Diabetic Nephropathy is defined as a persistent albuminuria and more commonly diagnosed by a urinary excretion of more than 300 mg/24 hour. It develops in around one third of patients with diabetes, with the AsiaPacific region being the most severely affected. It is one of the causes of renal failure and end-stage renal disease. Factors like smoki...