Sabahattin ErtuğrulDicle University · Faculty of Medicine
Sabahattin Ertuğrul
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91
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Publications
Publications (91)
Treacher Collins syndrome (TCS) is an autosomal dominant craniofacial developmental disorder with diverse phenotypic expression. It has a distinctive facial appearance that allows it to be easily identified. We present a case report of TCS with pyloric stenosis.
Objective:
Optimal care in the delivery room is important to decrease neonatal morbidity and mortality. We aimed to evaluate neonatal resuscitation practices in Turkish centers.
Materials and methods:
A cross-sectional survey consisted of a 91-item questionnaire focused on delivery room practices in neonatal resuscitation and was sent to 50 Turk...
Objective: Optimal care in the delivery room is important to decrease neonatal morbidity and mortality. We aimed to evaluate neonatal resuscitation practices in Turkish centers. Materials and Methods: A cross-sectional survey consisted of a 91-item questionnaire focused on delivery room practices in neonatal resuscitation and was sent to 50 Turkish...
Aplasia cutis congenita (ACC) is a rare heterogeneous group of diseases characterized by the absence of skin at birth. It affects males and females equally. It is usually located on the scalp and can be in different sizes from 0.5 up to 15 cm. Typically, it is sporadic, although hereditary cases have also been reported. In cases with bone tissue ab...
HASTA ÇOCUK VE TOPLUM İLİŞKİSİ
Çocuk psikoloji ve sosyolojisi
Background:
We have evaluated urinary tract infections (UTI) in neonatal indirect hyperbilirubinemia. Urine culture is not routinely requested in patients with indirect hyperbilirubinemia. However, debates continue about the frequency and investigation of UTI in neonatal indirect hyperbilirubinemia patients. The aim of this study was to determine...
Objective:
We aimed to determine the COVID-19 anxiety level in pregnant women who presented to an outpatient clinic during the COVID-19 pandemic.
Patients and methods:
This is a descriptive cross-sectional study including 203 of 310 pregnant women who presented to the outpatient clinic of a training and research hospital of the Ministry of Healt...
Objectives: A growing body of evidence suggests blood biomarker analysis may be a useful tool to aid in the elucidation of important pathophysiological mechanisms across a range of severities in newborn TBI. The aim of this research was to use blood biomarkers (NSE, s100B, GFAP, Tau and GDF-5) as a tool to advance knowledge of very high hyperbiliru...
Objectives: In this study, the relationship of cord blood Neutrophil Gelatinase-Associated Lipocalin (NGAL) with neonatal diseases was investigated.
Methods: NGAL levels were measured in the cord blood of 180 babies born between 2015 and 2016. Patients were classified according to maternal diseases, neonatal diseases and demographic characteristics...
Introduction:
Intravenous immunoglobulin (IVIG) has been widely used to treat the hemolytic disease of the newborn (HDN). Although it has been shown that IVIG treatment reduces the duration of phototherapy and hospitalization, the use of IVIG in hemolytic disease due to ABO incompatibility has been controversial in recent years. This study aimed t...
Objective:
In the neonatal period, diseases such as respiratory distress syndrome, necrotizing enterocolitis, bronchopulmonary dysplasia, retinopathy of prematurity, intraventricular hemorrhage, patent ductus arteriosus hypoxic-ischemic encephalopathy, and hyperbilirubinemia are frequently seen, despite being differently affected by the gestationa...
INTRODUCTION: Necrotizing enterocolitis is one of the most common serious gastrointestinal problems in neonatal intensive care units. In this study, the relationship between necrotizing enterocolitis cases and mortality was evaluated. METHODS: This study included 157 cases of necrotizing enterocolitis of stage II and above, who were followed up and...
Platelet parameters such as platelet count (PLT), mean platelet volume (MPV) and platelet mass index (PMI) are associated with physiological and pathological functions in various inflammatory diseases. The aim of the present study was to investigate whether platelet parameters were related to retinopathy of prematurity (ROP) in premature newborns....
Objective: Hypoxic ischemic encephalopathy (HIE) is a clinical condition that can result in severe morbidity and mortality due to hypoxia in the perinatal period. The aim of this study is to evaluate the role of cardiac biomarkers NTerminal pro Brain Natriuretic Peptide (NTproBNP) and Troponin I in hypoxic ischemic encephalopathy.
Methods: In this...
Objective:Late neonatal hypocalcemia (LNH) is a common metabolic problem associated with hypoparathyroidism, high phosphate intake and vitamin D deficiency, often presenting with seizures. In this cross-sectional study, we aimed to evaluate the role of vitamin D deficiency in LNH in Turkey and to describe the characteristics of affected newborns.Me...
Objectives
Amniotic band syndrome and osteogenesis imperfecta are two distinct diseases that develop due to structural defects of the collagen protein. In our paper, we report the concurrence of these two diseases rarely seen in the newborn period.
Case presentation
A female infant born at 33rd gestational week was found to have constrictive bands...
Background
Congenital disorders of glycosylation (CDG) are a group of hereditary diseases characterized by the deficiency of enzymes involved in proteins glycosylation. CDG are multisystem diseases, caused by more than 140 different genetic defects in glycoprotein and glycolipid glycan synthesis. The most known CDG is PMM2-CDG, in which the genetic...
Background
Hypophosphatasia is a rare autosomal dominant/recessive metabolic disease characterized by defective bone mineralization as a result of defective alkaline phosphatase activity caused by mutations in the gene encoding the tissue nonspecific alkaline phosphatase (TNSALP) enzyme. Patients with isolated dental manifestations, typically prese...
COVID-19 pandemisi dünya çapında yayılmaya devam ederken, risk altındaki popülasyonları belirlememiz ve onları korumak için uygun klinik bakım politikaları geliştirmemiz çok önemlidir. Yenidoğan SARS-CoV-2 enfeksiyonunun insidansı ve sonuçlarına ilişkin veriler ortaya çıkmaya devam etse de, öğrenilecek daha çok şey vardır. Şimdiye kadar ki kanıtlar...
Objective:
Late neonatal hypocalcemia (LNH) is a common metabolic problem associated with hypoparathyroidism, high phosphate intake and vitamin D deficiency (VDD), often presenting with seizures. In this cross-sectional study, we aimed to evaluate the role of VDD in LNH in Turkey and to describe the characteristics of affected newborns.
Methods:...
Objectives:
Postnatal corticosteroids are commonly used to treat bronchopulmonary dysplasia (BPD). We aimed to show whether S100 calcium-binding B (S100B), neuron-specific enolase (NSE), Tau protein or microtubule-associated protein tau (MAPT), and glial fibrillary acid protein (GFAP) levels would provide any evidence of early neurological damage...
OBJECTIVE: To determine the perinatal mortality rate in patients with HELLP syndrome in our clinic and to investigate the factors affecting perinatal mortality. It also makes recommendations to reduce perinatal mortality and contributes to the literature. STUDY DESIGN: Three-hundred-and-eighty-three patients were retrospectively evaluated in this c...
Background
This national cross-sectional survey aimed to assess the iodine status in pregnant women and their offspring, and also to demonstrate regional differences by measuring urinary iodine concentration (UIC). For each woman and her newborn a questionnaire was prepared with basic facts as age, parity number or birth weight and additional infor...
No consensus has been reached on which patent ductus arteriosus (PDAs) in preterm infants require treatment and if so, how, and when they should be treated. A prospective, multicenter, cohort study was conducted to compare the effects of conservative approaches and medical treatment options on ductal closure at discharge, surgical ligation, prematu...
Objective
To investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from neonatal intensive care units (NICUs) in Turkey.
Material and methods
A prospective cohort study was performed between April 1, 2016 and April 30, 2017. The study included VLBW infants admitted to level III NICUs. Perinatal and neonata...
Amaç: Bu çalışmada amacımız normal doğum hastalarını kontrol grubu olarak alarak anestezinin fetüs üzerine kısa dönem
etkilerini araştırmak, spinal ve genel anestezinin karşılaştırılmasını yapmaktır.
Yöntemler: Bu çalışmaya …… Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum kliniğine doğum yapmak için başvurmuş,
herhangi bir risk faktörü olm...
Abstract
Background Aplasia Cutis Congenita (ACC) is a rare genetic disorder characterized by restricted or widespread, complete or partial absence or scarcity of skin at birth. The lesions may occur on each surface of body, although localized scalp lesions are the most frequent pattern (70%). ACC can occur as an isolated defect or can be associate...
Bilici M, Fidancı-Dedeoğlu Z, Demir F, Akın A, Türe M, Balık H, Tan İ, Ertuğrul S. Prolonged QT dispersion is associated with pediatric syncope. Turk J Pediatr 2019; 61: 85-91. We aimed to find out whether QT dispersion can be used as a diagnostic marker in terms of syncope type, and recurrence risk. Fifty-two patients (28 male, 53.8%) admitted to...
Background To evaluate the prevalence, risk factors
and treatment of retinopathy of prematurity (ROP)
in Turkey and to establish screening criteria for this
condition.
Methods A prospective cohort study (TR-ROP) was
performed between 1 April 2016 and 30 April 2017 in
69 neonatal intensive care units (NICUs). Infants with a
birth weight (BW)≤1500 g...
We report on a preterm male (birth weight 1,100 g) with bilateral renal agenesis, a lethal malformation. Additionally, the child suffered from an atrial septal defect, ventricular septal defect, right aortic arch anomaly, a high type of anal atresia, vertebral anomalies, limbs defects (VACTERL association). The infant during first day of life was t...
As a multisystem infectious disease, there is an inflammation, which causes increase in acute phase reactants in brucellosis. The mean platelet volume (MPV), platelet distribution width (PDW), red cell distribution width (RDW), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) have been identified as markers of inflammatio...
Background
Healthcare-associated bloodstream infections (HCA-BSI) are a major cause of morbidity and mortality in neonatal intensive care units (NICUs).
Objectives
We aimed to determine the causative organisms and risk factors of HCA-BSIs in NICUs.
Methods
This study was performed between January 2011 and December 2014 in the neonatal intensive c...
Viral myositis associated with infections rarely may cause rhabdomyolysis. There is no any pediatric case with severe recurrent rhabdomyolysis triggered by infections in the literature. We reported a two-year-old boy who was hospitalized three times due to severe rhabdomyolysis associated with viral myositis in the winter months. This is the first...
Mediastinal cysts in neonates are infrequently reported. Enteric cysts in the
posterior mediastinum are mostly asymptomatic. Vertebral malformations may
contribute. Clinical presentation may include respiratory distress. Herein, we
report a case of mediastinal gastroenteric cyst and meningomyelocele in a neonate
presented respiratory distress signs...
The objective of this study was to determine the rate, independent risk factors, and outcomes of healthcare-associated infections in pediatric patients. This study was performed between 2011 and 2014 in pediatric clinic and intensive care unit. 86 patients and 86 control subjects were included in the study. Of 86 patients with nosocomial infections...
Objective: In this study; patients admitted to Diyarbakır Gazi Yaşargil Training and Research Hospital were evaluated retrospectively according to age groups for hepatitis A virus seroprevalence.
Methods: Anti HAV IgG and Anti HAV IgM test results of patients who admitted to our hospital for various reasons between January 2010 and December 2014 we...
Objective: Preterm neonates were approximately 70% of total low birth weight infants in developed countries. The aim of this study is to evaluate the low birth weight neonates who were hospitalized in the neonatal unit of our hospital between the years 2010-2011, retrospectively.
Methods: 626 infants that born with under 2500 gram were enrolled to...
Objective: Despite in diagnosis, treatment and the development of the neonatal intensive care, neonatal sepsis continues to be an important cause of morbidity and mortality. In this study, we aimed to evaluate that having followed and treated in neonates with culture-proven sepsis.
Methods: Between September 2012 -2014, the retrospective analysis w...
The purpose of this study was to compare the efficacy and safety of two different catheterization techniques of exchange transfusion (ET) used in the therapy of newborn jaundice: fully automated two-way ET technique and the classical one-way ET.
The study included babies at gestational age of >34 weeks. In total, 107 ETs were performed on 86 babies...
Paraoxonase-1 (PON-1) is an enzyme with glycoprotein structure that depends on calcium and exsist on high density lipoprotein (HDL) in the serum. The aim of this study is to evaluate PON-1 levels prior and after treatment and oxidant /anti-oxidant state and to determine the usability of PON-1 in neonatal sepsis.
35 neonatal sepsis patients and 35 h...
Objective: Diabetes is a significant risk factor for early onset of atherosclerosis. In this study, it was aimed to determine whether total homocysteine (tHcy), lipoprotein(a) [Lp(a)] and von Willebrand factor (vWF) levels have an early predictive value like glycolysated hemoglobin (HbA1c) levels in assessment of metabolic condition of children wit...
Objective: Diabetes is a significant risk factor for early onset of atherosclerosis. In this study, it was aimed to determine whether total homocysteine (tHcy), lipoprotein(a) [Lp(a)] and von Willebrand factor (vWF) levels have an early predictive value like glycolysated hemoglobin (HbA1c) levels in assessment of metabolic condition of children wit...
Physical child abuse may occur in a broad range of disorders from a mild soft tissue injury to a severe brain damage leading to death. The head trauma resulted from physical abuse is the main reason for the severe and fatal injuries in children, and arises with the clinical triad of externally seen trauma signs, subdural hemorrhage and retinal hemo...
Aim To investigate the oxidant-antioxidant status in babies born to preeclamptic mothers (BBPM).
Method The PON-1(Paraoxonase), TAS(Total Antioxidant Status) and TOS(Total Oxidant Status) levels were measured in the cord blood and venous blood (7day) of babies born to preeclamptic(n=31) and normotensive(N=25) mothers.
Results There was no differenc...
Abstract Objective: We aimed to determine the value of uNGAL levels in the early diagnosis of late-onset sepsis in preterms, and to compare CRP and PCT. Materials and Methods: Preterm infants admitted to the NICU between the ages of 7 to 28 days, were divided into two groups: 24 cases with clinical sepsis (gestational age 32.88±1.45w) and 20 cases...
Chylous ascites is a rare clinical entity occurring as the result of the extravasation of the chyle into the peritoneal cavity. A 20-day newborn admitted to our clinic with high level of thyroid stimulating hormone (TSH) and abdominal distension was diagnosed with chylous ascites and congenital hypothyroidism after paracentesis. Thyroid hormone sup...
Objective Urinary neutrophil gelatinase-associated lipocalin (uNGAL) has been suggested as a useful marker in limited recent studies for diagnosis of sepsis in pediatric and adult patients. We aimed to determine the value of uNGAL levels in early diagnosis of late-onset sepsis in preterms, and to compare CRP and PCT.
Materials and Methods Between F...
Additional congenital anomalies have often been found in patients with orofacial clefts. We wanted to find out the incidence and type of congenital malformations that may accompany cleft palate (CP) and cleft lip and palate (CLP) in babies born in the Konya region. A total of 121 newborn babies with CP or CLP were prospectively included in the stud...
To assess the clinical characteristics of patients with migraine.
The medical records of 76 patients diagnosed with migraine were reviewed using the ICHD-II 2004 diagnosis criteria. The patients were classified into three age groups: 3-6 yr olds (group I), 7-12 yr olds (group II), and 13-17 yr olds (group III).
Migraine was the most common cause of...
Freeman Sheldon syndrome (FSS) is a rare, multiple congenital contracture syndrome that is relatively well-known, since affected children have a striking appearance. This entity was historically referred to as the "whistling-face syndrome". Malignant hyperthermia and hyperpyrexia have been documented in FSS after general anesthesia related to the n...
Morquio's syndrome is an inherited disorder caused by the lack of the enzyme responsible for breakdown of keratan sulfate. The resulting buildup of keratan sulfate in tissues leads to skeletal dysplasia with other organ systems involvement. A four years old girl brought with the complaints of deformity in legs, abnormal gait, changed shape of chest...
Diabetes mellitus is a chronic endocrine and metabolic disease; characterized by hyperglycemia due to deficiency of either insulin secretion or insulin effect, causes severe complications in the long term. Insulin is a hormon synthesized at beta cells of pancreas and controls energy homeostasis. Either relative or absolute deficiency of insulin cau...
The aim of this study was to compare the effect of glycaemic control on oxidative stress and biochemical markers of endothelial activation in type 1 diabetic children.
Serum total cholesterol, HDL cholesterol, VLDL cholesterol, apolipoprotein A1, apolipoprotein B, HbA(1c), MDA, VEGF, NO, ICAM levels were assessed in 100 children with type 1 DM aged...
Homocysteine is an aminoacid which contains sulfur but not included in protein structure and can not be taken by diet. It's an intermediate product in methionine metabolism. Eighty-ninety percent of them are bound to albumin in plasma and remainder is free. The free part is not stable and quickly converted to oxidased forms. Plasma homocysteine lev...
Oro-fasio-dijital sendrom ağız boşluğu (yarık damak ve dil, anormal diş gelişimi, yüksek damak, dilde lobulasyon, dilde hamartom), yüz (frontal çıkıklık, fasiyal asimetri, hipertelorizm, fasiyal milia) ve parmak anomalileri (sindaktili, brakidaktili, klinodaktili, polidaktili) ile ortaya çıkan gelişimsel bir bozukluk olup 9 farklı tipi tanımlanmışt...
