S. Mahmood Al-qallaf

• PhD
• Professor (Associate) at University of Bahrain

Gastroesophageal reflux disease

Background and aims: Extensive polypharmacy in the elderly population affects their quality of life and medication compliance. The UK-developed LMQ-3 (Living with Medicine Questionnaire-3) is a valid instrument designed to quantify medicine burden.The aims of this study were to assess the medication-related burden among Bahraini elderly population...

Iodixanol is used intravenously to enhance the visibility of blood vessels in certain diagnostic procedures such as angiography. However, in some patients, it may cause allergic reactions, including rash, pruritus, and anaphylactoid reactions. The aim of this study is to assess the incidence and type of allergic reactions induced by iodixanol contr...

Multiple drug use is considered to be hazardous generally and in specific for the elderly because of their greater vulnerability to complications. The aim of this study is to determine the satisfaction and knowledge of elderly patients in Bahrain towards their multiple medications usage and to discover the prevalence of inappropriate polypharmacy a...

Background Tobacco prevention research traditionally focuses upon cigarette smoking, but there is also a need to implement and evaluate the usefulness of waterpipe tobacco smoking (WTS) interventions since it is considered less harmful than cigarettes. This study aimed to assess the impact of an educational intervention on WTS knowledge of health p...

Aim: Novel open chain and cyclized derivatives containing pyrazole scaffold were designed, synthesized and evaluated as antileishmanial compounds. Methodology & results: In silico reverse docking experiment suggested Leishmania major pteridine reductase (Lm-PTR1) as a putative target for the synthesized compounds. In vitro antileishmanial screenin...

Background: Colorectal cancer (CRC) is second in incidence rates in both genders in the Kingdom of Bahrain, with the number of new CRC cases sharply increasing in the last two decades. This study aimed to assess the levels of knowledge regarding CRC among people living in the Kingdom. Methods: A cross-sectional survey design was used to recruit a c...

Background: Colorectal cancer (CRC) is second in incidence rates in both genders in the Kingdom of Bahrain, with the number of new CRC cases sharply increasing in the last two decades. This study aimed to assess the levels of knowledge regarding CRC among people living in the Kingdom. Methods: A cross-sectional survey design was used to recruit a c...

Purpose: The aim of this project is to examine the tolerability of patients to the various possible side effects of organic nitrate and how that would affect their compliance. Methods: A PubMed search of the literature was conducted using the terms nitrates tolerability, nitrates side effects, nitrate compliance. Data for this study was collected f...

Pharmacotherapeutic agents obtained from living cells are called biologics. They include monoclonal antibodies and proteins. The development and use of new biological agents is expanding enormously. Biologics have the advantage of targeting specific cells or pathways which allowed increased efficacy and limited complications related to non-specific...

The aim of this study is to explore the efficacy and safety of metformin in weight loss in Bahraini population. This study was a cross-sectional survey of 100 Bahraini patients aged 20 or more randomly selected. Using a self-administered questionnaire, volunteers answered questions regarding purposes, doses, side effects and sources of information...

Background The number of children being diagnosed with type 1 diabetes mellitus (T1DM) is on the rise and has more than doubled in the past 10 years in Bahrain. Some studies have linked low vitamin D levels with an increased risk of diabetes. There are concerns regarding the variations in circulating 25(OH)D levels measured by different laboratorie...

Background & Objectives: Bahrain is reported to rank amongst the top 10 countries for diabetes prevalence worldwide. In particular, growing numbers of children are being diagnosed with Type 1 diabetes mellitus (T1DM).The objective of this study was to describe the dietary intake of Bahraini children with T1DM as compared to a sample of healthy coun...

Objectives: The aim of this study was to investigate awareness of Bahrainis regarding analgesics proper use, doses, side effects (SE), and sources of information. Methods: This was a cross-sectional survey of 100 Bahraini consumers aged 20 or more randomly selected. Using a self-administered questionnaire, volunteers answered questions regarding pu...

Objective: Patients′ understanding and perceptions of antibiotic use and resistance are crucial for the public health. This study aimed to explore the awareness of antibiotic utilization in 12 aspects among Bahraini patients attending health centers and community pharmacies and to find the associations of their awareness. Materials and Methods: A c...

Background: The prevalence of diabetes in the Middle East is amongst the highest worldwide; Bahrain ranks amongst the top 10 countries. In particular, increasing number of children are being diagnosed with type 1 diabetes mellitus (T1DM) posing a significant public health concern.

Background: The prevalence of diabetes in the Middle East is amongst the highest worldwide; Bahrain ranks amongst the top 10 countries. In particular, increasing number of children are being diagnosed with type 1 diabetes mellitus (T1DM) posing a significant public health concern. Objective: To evaluate the magnitude of type 1 diabetes in Bahrain....

Type 1 Diabetes in Children: The Bahraini Dilemma - Volume 72 Issue OCE4 - K. Hart, Y. Nicolaidou, A. O. Musaiger, S. M. Alqallaf, F. Al-Haddad

The expression and function of P2X(7) receptors in osteoclasts is well established, but less is known about their role in osteoblast-like cells. A study in P2X(7) receptor knockout mice suggested the involvement of these receptors in bone formation. We have investigated the expression and pharmacology of several P2X receptors in two human osteosarc...