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Introduction
Publications
Publications (7)
Cocrystallization technique has gained increasing interest due to its ability to modify the physicochem-ical properties of a drug substance. Efavirenz comes under biopharmaceutical classification system class II compounds that denote the low solubility and high permeability nature of the drug. Thus, the main aim of this study is to develop efaviren...
Cocrystallization technique has gained increasing interest due to its ability to modify the physicochemical properties of a drug substance. Efavirenz comes under biopharmaceutical classification system class II compounds that denote the low solubility and high permeability nature of the drug. Thus, the main aim of this study is to develop efavirenz...
Efavirenz (EFV) is a Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI) class of antiretroviral drug that is included in antiretroviral therapy to treat Human Immunodeficiency Virus (HIV) patients to increase the life-span by avoiding them to develop Acquired Immune Deficiency Syndrome (AIDS). One of the major drawbacks of EFV is its solubilit...
The present study was performed to find out the structural similarity of hydroalcoholic extract of abutilon indicum and standard non-steroidal anti-inflammatory drugs (NSAIDs) using various analytical and chromatography techniques. The characterization was performed by fourier transform infrared spectrophotometer (FTIR), UV–Vis spectrophotometer, t...
Darunavir (DRV) is a peptidic protease inhibitor class of antiretroviral drug which is regularly included in the antiretroviral therapy with several other drugs to treat Human immunodeficiency virus (HIV) patients to avoid those developing Acquired Immune Deficiency Syndrome (AIDS). In this research paper, an accurate, precise, reproducible, simple...
Nearly 40% of drugs coming to the market nowadays are having poor solvency related issues and 70% molecules in discovery pipeline are in effect fundamentally insoluble in water. Nanocrystals is an unmistakable instrument to tackle the issue identified with poor fluid solvency and helps in improving the bioavailability of various drugs as presented...
The aim of the present study was to prepare and evaluate microspheres of Eudragit (RS, RL and RSPO) containing an anticancer drug 5-FU. Microspheres were prepared by O/O solvent evaporation method using a acetone/liquid paraffin system. Magnesium stearate was used as the droplet stabilizer and n-hexane was added to harden the microspheres. The prep...
