Ryusuke Kakigi

Ryusuke Kakigi
The Graduate University for Advanced Studies, SOKENDAI | SOKENDAI

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658
Publications
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19,777
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Publications

Publications (658)
Article
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The present study performed a brain-wide network analysis of resting-state magnetoencephalograms recorded from 53 healthy participants to visualize elaborate brain maps of phase- and amplitude-derived graph-theory metrics at different frequencies. To achieve this, we conducted a vertex-wise computation of threshold-independent graph metrics by comb...
Article
The present study investigated the effects of hypocapnia and hypercapnia on human somatosensory processing by utilizing somatosensory evoked magnetic fields (SEFs) with magnetoencephalography (MEG). Thirteen volunteers participated in two experiments separately to measure respiratory and cardiovascular data and SEFs. Both experiments consisted of a...
Article
Full-text available
We investigated the emotion perception process based on hospitality expertise. Forty subjects were divided into the OMOTENASHI group working at inns considered to represent the spirit of hospitality, OMOTENASHI in Japan, and CONTROL group without experience in the hospitality industry. We presented neutral, happy, and angry faces to investigate P10...
Article
Full-text available
The face has a large amount of information that is useful for humans in social communication. Recently, non-invasive methods have been used to investigate human brain activity related to perception and cognition processes. Electroencephalography (EEG) and magnetoencephalography (MEG) have excellent temporal resolution and reasonably good spatial re...
Article
Nerve conduction studies (NCS) are an essential aspect of the assessment of patients with peripheral neuropathies. However, conventional NCS do not reflect activation of small afferent fibers, including Aδ and C fibers. A definitive gold standard for laboratory evaluation of these fibers is still needed and therefore, clinical evaluation remains fu...
Article
We have been studying the underlying mechanisms of face perception in humans using magneto-(MEG), electroencephalography (EEG) and near-infrared spectroscopy (NIRS). In this lecture, I will mainly focus on the development of face perception in infants. NIRS is a spectroscopic method using the near-infrared region of the electromagnetic spectrum (fr...
Article
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Using event-related potentials (ERPs), we investigated the effects of passive heat stress and recovery on the human cognitive function with Flanker tasks, involving congruent and incongruent stimuli. We hypothesized that modulation of the peak amplitude and latency of the P300 component in ERP waveforms would differ with task difficulty during pass...
Article
Although conditioned pain modulation (CPM) is considered to represent descending pain inhibitory mechanisms triggered by noxious stimuli applied to a remote area, there have been no previous studies comparing CPM between pain and tactile systems. In this study, we compared CPM between the two systems objectively using blink reflexes. Intra-epiderma...
Article
Full-text available
The interaction between the somatosensory and motor systems is important for control of movement in humans. Cortical activity related to somatosensory response and sensory perception is modulated by the influence of movement executing mechanisms. This phenomenon has been observed as inhibition in the short‐latency components of somatosensory evoked...
Article
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Itch is an unpleasant and aversive somatosensory experience. These negative emotions significantly affect mental health in patients with chronic itch; it is therefore important to understand the brain mechanism of negative emotions due to itch. The amygdala is a key hub of networks regulating negative emotions due to itch. However, the exact networ...
Article
Full-text available
Visual working memory (vWM) is an important ability required for various cognitive tasks although its neural underpinnings remain unclear. While many studies have focused on theta (4-7 Hz) and gamma (> 30 Hz) rhythms as a substrate of vWM, here we show that temporal signals embedded in alpha (8-12 Hz) and beta (13-30 Hz) bands can be a good predict...
Preprint
Visual working memory (vWM) is an important ability required for various cognitive tasks although its neural underpinnings remain controversial. While many studies have focused on theta (4-7 Hz) and gamma (> 30 Hz) rhythms as a substrate of vWM, here we show that temporal signals embedded in alpha (8-12 Hz) and beta (13-30 Hz) bands can be a good p...
Article
This study examined the development of ability to recognize familiar face in drawings in infants aged 6–8 months. In Experiment 1, we investigated infants’ recognition of their mothers’ faces by testing their visual preference for their mother’s face over a stranger’s face under three conditions: photographs, cartoons produced by online software th...
Article
Full-text available
Background: School-age children with attention deficit hyperactivity disorder (ADHD) have difficulties in interpersonal relationships, in addition to impaired facial expression perception and recognition. For successful social interactions, the ability to discriminate between familiar and unfamiliar faces is critical. However, there are no publish...
Article
The present study investigated the effect of whole-body skin cooling on somatosensory ascending processing by utilizing somatosensory-evoked potentials (SEPs) and motor execution as well as inhibitory processing by event-related potentials (ERPs). Fourteen healthy participants wearing a water-perfused suit performed two sessions (Sessions 1 and 2)...
Article
Full-text available
The posterior insula (pIns) is a major brain region that receives itch-related signals from the periphery and transfers these signals to broad areas in the brain. Previous brain imaging studies have successfully identified brain regions that respond to itch stimuli. However, it is still unknown which brain regions receive and process itch-related s...
Article
We investigated the remote effect on corticospinal excitability of resting left and right hand muscles during motor execution and motor imagery when performing left or right foot plantar flexion. Fifteen right-handed subjects performed two conditions with three tasks: Condition (Motor Execution (ME) vs. Motor Imagery (MI)): Task (Control, Ipsilater...
Article
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Cognitive performances may improve after acute moderate exercise, but not after prolonged and/or heavy exercise. The present study aimed to investigate the effects of environmental temperature during exercise on human cognitive processing. Fifteen healthy males performed four bouts of a 15‐min cycling exercise with a 10‐min rest between each bout,...
Article
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Exposure to auditory white noise has been shown to facilitate cognitive function. This phenomenon is often called stochastic resonance, and a moderate amount of auditory noise has been suggested to benefit individuals in hypodopaminergic states. Previous studies using psychophysic methods reported that stochastic resonance was sensitive to stimulus...
Article
Neural oscillatory signals has been associated with many high-level functions (e.g. attention and working memory), because they reflect correlated behaviors of neural population that would facilitate the information transfer in the brain. On the other hand, a decreased power of oscillation (event-related desynchronization, ERD) has been associated...
Article
View-invariant face processing emerges early in life. A previous study (Nakato et al., 2009) measured infant hemodynamic responses to faces from the frontal and profile views in the bilateral temporal areas, which have been reported to be involved in face processing using near-infrared spectroscopy. It was reported that 5-month-old infants showed i...
Article
Full-text available
Some researchers in aesthetics assume visual features related to aesthetic perception (e.g. golden ratio and symmetry) commonly embedded in masterpieces. If this is true, an intriguing hypothesis is that the human brain has neural circuitry specialized for the processing of visual beauty. We presently tested this hypothesis by combining a neuroimag...
Article
Full-text available
An intention to move distorts the perception of time. For example, a visual stimulus presented during the preparation of manual movements is perceived longer than actual. Although neural mechanisms underlying this action‐induced time distortion have been unclear, here we propose a new model in which the distortion is caused by a sensory–motor inter...
Article
Exposure to auditory white noise has been shown to facilitate cognitive function. This phenomenon is called stochastic resonance. The present study examined the effects of white noise duration on behavioral data [reaction time (RT), the SD of RT, and error rates] and the N140 and P300 components of event-related potentials in somatosensory Go/No-go...
Article
Full-text available
Photophobia is a common condition in which bright light causes an unpleasant feeling due to increased sensitivity to light. In addition to discomfort, photophobia may be accompanied by visual dysfunction. The present study was conducted in order to examine whether visual evoked cortical responses contribute to the assessment of visual dysfunction d...
Article
Background The present study investigated the characteristics of temperature‐related evoked neural activities to baseline skin temperatures on target and adjacent sites using contact heat evoked potentials (CHEPs). Methods CHEPs were recorded from 12 normal subjects during three stimuli: target temperatures for Warm, Hot, and Pain were set to 41°C...
Article
Previous studies have demonstrated the cortical mechanisms for the gradient of spatial attention in vision and audition, whereas those for touch have yet to be elucidated in detail. In order to examine the within-hand gradient of tactile spatial attention in the cerebral cortex, we used magnetoencephalography (MEG) to record cortical responses to a...
Preprint
Neural oscillatory signals has been associated with many high-level functions (e.g. attention and working memory), because they reflect correlated behaviors of neural population that would facilitate the information transfer in the brain. On the other hand, a decreased power of oscillation (event-related desynchronization or ERD) has been associate...
Article
Introduction Previous studies have demonstrated the cortical mechanisms for the gradient of spatial attention in vision and audition, whereas those for touch have yet to be elucidated in detail. We used magnetoencephalography (MEG) to examine the within-hand gradient of tactile spatial attention in the cerebral cortex. Methods We recorded cortical...
Article
Subjective tinnitus is one of the most common diseases in industrialized countries; however, the mechanisms of tinnitus generation and maintenance remain elusive. Currently, there are no objective parameters in the diagnosis of tinnitus. In order to meet the overwhelming demand for evidence-based tinnitus therapy, an objective measurement of subjec...
Article
Full-text available
Recent data showed that, in Caucasian infants, perceptual narrowing occurs for own-race adult faces between 3 and 9 months of age, possibly as a consequence of the extensive amount of social and perceptual experience accumulated with caregivers and/or other adult individuals of the same race of the caregiver. The neural correlates of this developme...
Article
The cover image, by Megumi Kobayashi et al., is based on the Paper Perceptual narrowing towards adult faces is a cross-cultural phenomenon in infancy: a behavioral and near-infrared spectroscopy study with Japanese infants, DOI: 10.1111/desc.12498.
Article
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Somatosensory input to the brain is known to be modulated during voluntary movement. It has been demonstrated that the response in the primary somatosensory cortex (SI) is generally gated during simple movement of the corresponding body part. This study investigated sensorimotor integration in the SI during manual movement using a motor task combin...
Article
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Effective behaviors optimized for various situations are enabled by various sensory information. How does the brain deal simultaneously with information from different sensory systems? Investigation of multisensory processing began from neuroanatomical and neurophysiological studies at the level of single neurons. Accumulation of knowledge concerni...
Article
We investigated the modulation of somatosensory evoked potentials (SEPs) during force generation and force relaxation in a visuomotor tracking task. The target force line moved up continuously from 0% to 20% of maximal voluntary contraction (MVC) (the force generation phase: FG phase) and moved down from 20% to 0% of MVC (the force relaxation phase...
Article
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The opercular somatosensory region (OP) plays an indispensable role in pain perception. In the present study, we investigated the neurophysiological effects of transcranial direct current stimulation (tDCS) over the OP. Somatosensory-evoked magnetic fields following noxious intraepidermal electrical stimulation to the left index finger (pain-SEFs)...
Article
A weak preceding sound stimulus attenuates the startle response evoked by an intense sound stimulus. Like startle reflexes, change-related auditory responses are suppressed by a weak leading stimulus (ie, a prepulse). We aim to examine whether a prepulse inhibits cerebral responses to the sound offset and how the prepulse magnitude affects the degr...
Article
Full-text available
Attention is the ability to extract task-relevant information and reject irrelevant information in order to avoid excessive information processing in the nervous system, and influences task performance in daily life including physical and sporting activities. Basic attentional phenomena at the behavioral and neural levels have recently been employe...
Article
Full-text available
In our daily life, we are successively exposed to frequency-modulated (FM) sounds that play an important role in speech and species-specific communication. Previous studies demonstrated that repetitive exposure to identical pure tones resulted in decreased neural activity. However, the effects of repetitively presented FM sounds on neural activity...
Article
Tinnitus is a phantom auditory perception without an external sound source and is one of the most common public health concerns that impair the quality of life of many individuals. However, its neural mechanisms remain unclear. We herein examined population-level frequency tuning in the auditory cortex of unilateral tinnitus patients with similar h...
Article
When exposed to self-face images, individuals often experience embarrassment, which is enhanced by being observed. This self-evaluative emotion is related to activity in the right anterior insula and the functional connectivity between the anterior cingulate and prefrontal cortices. Coupling between cognitive evaluation of self-face images and emot...
Article
Full-text available
Despite their indispensable roles in sensory processing, little is known about inhibitory interneurons in humans. Inhibitory postsynaptic potentials cannot be recorded non-invasively, at least in a pure form, in humans. We herein sought to clarify whether prepulse inhibition (PPI) in the auditory cortex reflected inhibition via interneurons using m...
Chapter
The human visual system consists of two main separate pathways, the ventral (what) and dorsal (where) pathways, which is similar to that in monkeys. The ventral pathway is involved in the processing of shapes and objects as well as color perception, whereas the dorsal pathway is responsible for processing location and motion as well as three-dimens...
Chapter
Magnetoencephalography (MEG) is a powerful noninvasive tool for examining the temporal and spatial aspects of sensory processing in the brain. In this chapter, MEG responses elicited by innocuous and noxious somatic stimuli were reviewed. The development of devices for the selective stimulation of each peripheral receptor (i.e., A-beta mechanorecep...
Article
Full-text available
Sudden sensorineural hearing loss (SSHL) is characterized by acute, idiopathic hearing loss. The estimated incidence rate is 5-30 cases per 100,000 people per year. The causes of SSHL and the mechanisms underlying SSHL currently remain unknown. Based on several hypotheses such as a circulatory disturbance to the cochlea, viral infection, and autoim...
Article
Full-text available
Magnetoencephalography (MEG) and electroencephalography (EEG) are invaluable neuroscientific tools for unveiling human neural dynamics in three dimensions (space, time, and frequency), which are associated with a wide variety of perceptions, cognition, and actions. MEG/EEG also provides different categories of neuronal indices including activity ma...
Book
This book presents an overview of the recent advances in clinical applications of magnetoencephalography (MEG). With the expansion of MEG to neuroscience, its clinical applications have also been actively pursued. Featuring contributions from prominent experts in the fields, the book focuses on the current status of the application of MEG, not only...
Article
Full-text available
Frequency-modulated sounds play an important role in our daily social life. However, it currently remains unclear whether frequency modulation rates affect neural activity in the human auditory cortex. In the present study, using magnetoencephalography, we investigated the auditory evoked N1m and sustained field responses elicited by temporally rep...
Article
Full-text available
Background The latency and amplitude of visual evoked cortical responses are known to be affected by refractive states, suggesting that they may be used as an objective index of refractive errors. In order to establish an easy and reliable method for this purpose, we herein examined the effects of refractive errors on visual evoked magnetic fields...
Article
The rapid detection of changes in sensory information is an essential process for survival. Individual humans are thought to have their own intrinsic preattentive responsiveness to sensory changes. Here we sought to determine the relationship between auditory change-related responses and personality traits, using event-related potentials. A change-...
Article
Full-text available
Human adults show better face recognition for own-race faces than other-race faces (e.g., Feingold, 1914; Meissner & Bringham, 2001). Developmental studies revealed that this recognition bias for own-race faces emerges in infancy (for a review, see Lee et al., 2011). At three months of age, infants can discriminate as readily between two own-race f...
Article
Itching can be suppressed by scratching. However, scratching may aggravate itch symptoms by damaging the skin. Therefore, identifying an alternative approach to suppress itching is of clinical importance. The aim of the present study was to determine whether a transcranial direct current stimulation (tDCS) was useful for itch relief. The present st...
Article
Full-text available
There have been no reports concerning the self-face perception in patients with anorexia nervosa (AN). The purpose of this study was to compare the neuronal correlates of viewing self-face images (i.e. images of familiar face) and stranger-face images (i.e. images of an unfamiliar face) in female adolescents with and without AN. We used near-infrar...
Article
Full-text available
The main objectives of this study were to investigate the development of face perception in Japanese children, focusing on the changes in face processing strategies (holistic and/or configural vs. feature-based) that occur during childhood. To achieve this, we analyzed the face-related N170 component, evoked by upright face, inverted face, and eyes...
Article
Full-text available
In everyday life, attention is adaptively directed to a stimulus and action in multisensory environments. Recent studies have demonstrated that the functionality of attention and related brain activities are improved by exercise and sports activities. We herein reviewed our previous studies on the neural mechanisms of attention using magnetoencepha...
Article
Itch is an unpleasant somatic sensation that evokes the urge to scratch. Chronic itch is a severe problem that diminishes quality of life. There are many patients suffering from chronic itch across the world. The brain is the final terminal to receive itch-related signals from the body and plays an important role in perceiving the itch sensation. T...
Article
Although many neuroimaging studies using functional magnetic resonance imaging have shown the neuronal networks for motor execution and inhibition processing, the precise activation timing of each brain region is not yet well understood. In the present study, we investigated the temporal dynamics of neural activities in multiple brain regions using...
Article
Cortical neurons are excited by signals from the thalamus that are conducted via thalamocortical fibers. As the cortex receives these signals, electric currents are conducted through the apical dendrites of pyramidal cells in the cerebral cortex. These electric currents generate magnetic fields. These electric and magnetic currents can be recorded...
Article
We investigated the effects of task repetition on the N140 and P300 components of event-related potentials (ERPs) in somatosensory Go/No-go paradigms. A Go or No-go stimulus was presented to the second or fifth digit of the left hand, respectively, at the same probability, and subjects had to respond by pushing a button with their right thumb as qu...
Article
Full-text available
Humans' ability to recognize objects is remarkably robust across a variety of views unless faces are presented upside-down. Whether this face inversion effect (FIE) results from qualitative (distinct mechanisms) or quantitative processing differences (a matter of degree within common mechanisms) between upright and inverted faces has been intensely...
Article
The purpose of the present study was to investigate the effect of mastication on Go/No-go decisional processing using event-related potentials (ERPs). Thirteen normal subjects underwent seven sessions of a somatosensory Go/No-go paradigm for approximately 4min; Pre, and Post 1, 2, 3, 4, 5, and 6. The Control condition included the same seven sessio...
Article
Many previous theories of perceptual awareness assume that a conscious representation of a stimulus is created from sensory information carried by an onset (appearance) of the stimulus. In contrast, here we provide behavioral and neural evidence for a new phenomenon in which conscious perception is directly triggered by an offset (disappearance) of...
Article
Full-text available
Recent studies have shown that meditation inhibits or relieves pain perception. To clarify the underlying mechanisms for this phenomenon, neuroimaging methods, such as functional magnetic resonance imaging, and neurophysiological methods, such as magnetoencephalography and electroencephalography, have been used. However, it has been difficult to in...
Article
Although atypical processing of biological motion (BM) in individuals with autism spectrum disorder (ASD) has been reported, the temporal profile of the neural response to BM is not well explored. In the current study, event-related potentials (ERPs) were measured in 12 individuals with ASD, aged 8–22 years, and 12 age- and gender-matched normal co...
Article
Itch is a complex sensory and emotional experience. Functional brain imaging studies have been performed to identify brain regions associated with this complex experience, and these studies reported that several brain regions are activated by itch stimuli. The possible roles of these regions in itch perception and difference in cerebral mechanism b...
Article
Full-text available
IntroductionPrevious studies demonstrated that a decrement in the N1m response, a major deflection in the auditory evoked response, with sound repetition was mainly caused by bottom-up driven neural refractory periods following brain activation due to sound stimulations. However, it currently remains unknown whether this decrement occurs with a rep...
Data
Audio S1. An exemplary sound representing repetitive tone sequencing and subsequent repetitive silence sequencing as shown in Figure 1.