Ruzanna Shushanyan

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Yerevan State University | YSU · Human and Animal Physiology

High altitude characterized by the low partial pressure of the oxygen is a life-threatening condition that contributes to the development of acute pulmonary edema and hypoxic lung injury. In this study, we aimed to investigate the contribution of some inflammatory and oxidative stress markers along with antioxidant system enzymes in the pathogenesi...

Across a wide variety of global contexts, the role of higher education is exceptionally important for sustainable economic development Therefore, the implementation of educational reforms to support integrative and internationally-oriented doctoral studies is one of the most important challenges for policymakers. This study aims to investigate the...

Introduction: The objective of this study was to investigate the heart rate variability indicators of students who had contracted COVID-19 after performing physical activity. The aim was to uncover the potential cardiac complications and dysregulations of the autonomic nervous system. Material and Method: We explored about 11 heart rate variability...

A high­altitude environment is known as an extreme condition characterized by low barometric pressure and oxygen deficiency that can affect the nervous system in distinctive ways. High­altitude cerebral edema is one of the consequences of neurological disorders that harm human health. Maladaptation in high altitude conditions confronted by low baro...

Breast cancer is the most worrisome health issue among women worldwide with a high metastatic risk that is exponentially increasing. Thus, new therapeutic approaches are needed for its prevention and understanding of the essential mechanisms underlying carcinogenesis in the breast. Nitric oxide, as an intermediate product of arginine metabolism, pl...

This study aimed to investigate the hemodynamic and HRV indicators for students under physical load during the post­COVID­19 period to reveal cardiac dysfunctions and dysregulations of the autonomic nervous system. 44 female students were included in the current study. The hemodynamic and HRV indicators were investigated immediately after a 5­minut...

Viper bites pose a significant public health issue in Armenia, even within urban areas, often resulting in clotting disorders, hypofibrinogenemia, and tissue necrosis in humans. This study investigates histopathological changes in various tissues during mice envenomation by West-Asian blunt-nosed viper (Macrovipera lebetina obtusa) venom, as well a...

High-altitude environments present extreme conditions characterized by low barometric pressure and oxygen deficiency, which can disrupt brain functioning and cause edema formation. The objective of the present study is to investigate several biomolecule expressions and their role in the development of High Altitude Cerebral Edema in a rat model. Sp...

Elevated altitudes accompanied by low barometric pressure and acute oxygen deficiency, pose a significant risk for the development of High-Altitude Cerebral Edema in the brain. The resultant HACE is a potentially fatal neurological disorder that triggers a neuroinflammatory response and leads to significant changes in the redox homeostasis of the b...

Purpose The hematological changes in COVID-19 patients continue to receive great attention, especially in the field of public health. To our knowledge, coronavirus disease may be identified based on the severity of illness, and the study of peripheral blood smears may offer important information to facilitate the identification. Thus, we evaluated...

High altitude sickness is a life-threatening disease that occurs among acclimatized individuals working or living at a high altitude accompanied by hypobaric hypoxia exposure. The prolonged influence of hypobaric hypoxia on the brain may trigger neuronal damage and cell death due to an oxygen deficiency. The purpose of the current study was to inve...

This study aimed to investigate the hemodynamic and HRV indicators of students under physical load during the post-COVID-19 period to reveal cardiac dysfunctions and dysregulations of the autonomic nervous system. 44 female students were included in the current study. The hemodynamic and HRV indicators were studied immediately after a 5-minute phys...

Acute hypobaric hypoxia induces various pathological mechanisms that lead to the development of oxidative stress damaging the neurons of the rat’s brain and therefore reducing their electrical impulse activity. Acute hypobaric hypoxia at an altitude of 7500 m (64–58 mm Hg) suppresses the biosynthetic processes in the brain that in turn causes amida...

https://ssrn.com/abstract=4541283

Hypobaric hypoxia is one of the causative factors for developing high-altitude cerebral edema (HACE), which is a life-threatening disorder for unacclimated individuals. HACE has accompanied by oxygen deficiency and mitochondrial dysfunction which leads to oxidative damage and apoptosis of the neurons. NO (nitric oxide) is an intracellular messenger...

The pandemic 2019 novel coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2) infection, has posed a severe threat to global public health. The haematological changes among patients with Covid-19 remain the core of interest, especially in public health. However, to the best of our knowledge about coro...

Hypobaric hypoxia causes degenerative changes in different parts of the brain, which leads to the formation of cerebral edema. This study aimed to investigate the morphohistological changes in the brain of rats exposed to hypobaric hypoxia. In particular, the hippocampus, cerebral cortex, and striatum were studied. Animals were exposed to hypobaric...

Scientific research in the field of healthcare contributes to solving not only medical but also economic and social issues. One of the latest trends is the growing interest in evaluating the effectiveness of research conducted. In the current study, we have hypothesized that science contributes to the reduction of the Cancer Mortality Rate (CMR) by...

Bibliometric analysis is widely used for the assessment of collaboration both at the domestic and international levels, which has been known as one of the essential parts of academic performance and enhancement of scientific productivity and visibility. Evaluation of national and international cooperation in the framework of jointly published paper...

Scientometric analysis of the research results is recognized as one of the most important tools for monitoring the academic impact and scientific advancement at various levels. The study of publications in a particular area is a good indicator of the state of research work. A study of publications provides a concise understanding of the direction o...