Rupert Gerzer

• Prof. Dr. med.
• Provost at Skolkovo Institute of Science and Technology

Ambulatory long term cardiac diagnostics is still not optimally solved. We have developed a new system that can overcome this gap in diagnostics. The new system consists of an adhesive patch-like wearable miniaturized device for electrocardiogram (ECG) data acquisition with further processing of acquired data. The new patch-like wearable device is...

The growing of Earth population and the need of food provisioning to remote areas make pervasive agriculture the research problem of high priority. In this work, we present a 2D/3D scanning system with the intelligent data processing mechanism which can be easily deployed in a greenhouse. The proposed solution enables finding of correlations betwee...

Without effective countermeasures, the musculoskeletal system is altered by the microgravity environment of long-duration spaceflight, resulting in atrophy of bone and muscle tissue, as well as in deficits in the function of cartilage, tendons, and vertebral disks. While inflight countermeasures implemented on the International Space Station have e...

Drug safety and efficacy are highly variable among patients. Most patients will experience the desired drug effect, but some may suffer from adverse drug reactions or gain no benefit. Pharmacogenetic testing serves as a pre-treatment diagnostic option in situations where failure or adverse events should be avoided at all costs. One such situation i...

Training young researchers in the field of space life sciences is essential to vitalize the future of spaceflight. In 2009, the DLR Institute of Aerospace Medicine established the Helmholtz Space Life Sciences Research School (SpaceLife) in cooperation with several universities, starting with 22 doctoral candidates. SpaceLife offered an intensive t...

Mit einer aktuellen Studie konnten bekannte Daten uber Inzidenzen von medizinischen Vorfallen bei Flugen bestatigt werden. Allerdings wurde die Qualitat medizinischer Notfallausrustung in Verkehrsflugzeugen von behandelnden Arzten als nicht immer adaquat beurteilt. Des Weiteren haben verschiedene Fluglinien, die sich darauf verlassen, unentgeltlich...

The Institute of Aerospace Medicine of DLR has a long experience with Artificial Gravity. Beginning with a long arm centrifuge built in the 1950s DLR has done research under artificial gravity conditions for more than 60 years. A large number of studies in the field of fundamental research or applied science have been performed successfully. In 200...

Besides their role in immune system host defense, there is growing evidence that macrophages may also be important regulators of salt homeostasis and blood pressure by a TonEBP-VEGF-C dependent buffering mechanism. As macrophages are known to accumulate in the skin of rats fed under high salt diet conditions and are pivotal for removal of high salt...

In den letzten 3 Jahren entstand im Deutschen Zentrum für Luft- und Raumfahrt (DLR) in Köln mit :envihab eine neuartige Forschungsanlage zur Erforschung des gesamten Menschen unter verschiedensten (Umwelt-)Bedingungen. Hauptziel der Forschungsarbeiten des Instituts für Luft- und Raumfahrtmedizin in:envihab ist die Verbindung luft- und raumfahrtmedi...

The fast-rotating 2-D clinostat, a ground-based facility for investigations in simulated microgravity, is mainly used for experiments with cell suspensions. Here, we describe the adaptation of a 2-D clinostat for adherent cell investigations using commercially available slide flasks. As a gradient of residual accelerations is present in the slide f...

Recent studies support the hypothesis that macrophages are not only essential for efficient immune responses, but are also regulators of local tissue electrolyte composition and hence arterial hypertension. Blockade of this macrophage-dependent regulatory axis resulted in skin electrolyte accumulation and blood pressure increase. Based on the obser...

The steady-state concept of Na(+) homeostasis, based on short-term investigations of responses to high salt intake, maintains that dietary Na(+) is rapidly eliminated into urine, thereby achieving constant total-body Na(+) and water content. We introduced the reverse experimental approach by fixing salt intake of men participating in space flight s...

Wie und durch welche physiologischen Wege Isolation das Verhalten von Blutdruck beeinflusst, war unsere Fragestellung für MARS 520. Nach gegenwärtigem Wissenstand wird langfristige Blutdruckregulation hauptsächlich durch den Wasser-Elektrolyt-Haushalt betrieben, aber auch Umwelt-, psychosoziale und stressbedingte Einflüsse modulieren das Blutdruckv...

For a long time, sodium balance appeared to be a "done deal" and was thought to be well understood. However, experiments in preparation of space missions showed that the concept of osmotic sodium storage and close correlations of sodium with water balance are only part of the regulatory mechanisms of body salt. By now it has turned out that the hum...

Das DLR-Institut für Luft- und Raumfahrtmedizin feierte 2012 seinen 60. Gründungstag. Damit blicken wir auf eine lange Tradition lebenswissenschaftlicher Forschung zum Erhalt und zur Förderung von Gesundheit und Leistungsfähigkeit des Menschen in der mobilen Gesellschaft- ob in Verkehr, Luft- oder Raumfahrt - zurück. Im Zentrum unserer Forschung st...

As a new modularly designed research facility for medical research, :envihab’s purpose is to study under strictly standardized conditions the complex problems presented by a closed life-support system (:envihab = environmental habitat) and the interactions between humans and the environment and possible countermeasures. The main goal of :envihab is...

Commercial human spaceflight has excellent economic and technical perspectives in the next decades. Passengers will be persons from a general population differing from culture, age, gender and health status. They all will have to withstand physical loads of spaceflight such as acceleration and deceleration forces, microgravity, vibration, noise and...

The steady-state concept of Na + homeostasis, based on short-term investigations of responses to high salt intake, maintains that dietary Na + is rapidly eliminated into urine, thereby achieving constant total-body Na + and water content. We introduced the reverse experimental approach by fixing salt intake of men participating in space flight simu...

In the field of space life sciences, the demand of an interdisciplinary and specific training of young researchers is high due to the complex interaction of medical, biological, physical, technical and other questions. The Helmholtz Space Life Sciences Research School (SpaceLife) offers an excellent interdisciplinary training for doctoral students...

The membrane-bound guanylyl cyclases A and B (GC-A/B), which are receptors for natriuretic peptides, are expressed in cancer cells including melanomas and may represent new anticancer targets. Here, we report down-regulation of GC-A/B expression in human metastatic melanoma cells at simulated weightlessness in comparison to 1g conditions, suggestin...

In den letzten Jahren gelang es, basierend auf Ergebnissen von Forschungsprojekten uber den Salzhaushalt des Menschen in Schwerelosigkeit, vollig neue Erkenntnisse uber Funktionsweisen des menschlichen Korpers zu erhalten. Diese Erkenntnisse gehen so weit, dass sie in Vielem unser Lehrbuchwissen verandern und neue Therapiekonzepte ermoglichen konne...

In the field of space life sciences, the demand of an interdisciplinary and specific training of young researchers is high due to the complex interaction of medical, biological, physical, technical and other questions. The Helmholtz Space Life Sciences Research School (SpaceLife) offers an excellent interdisciplinary training for doctoral students...