Rui Amaral Mendes

Rui Amaral Mendes
Case Western Reserve University | CWRU · Department of Oral and Maxillofacial Medicine and Diagnostic Sciences

DMD, PhD

About

79
Publications
20,846
Reads
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1,258
Citations
Introduction
Professor Rui Amaral Mendes is a graduate from the University of Porto and holds a PhD in Oral and Maxillofacial Surgery and Pathology from the VU Universiteit Amsterdam. He has held positions as Professor of Oral Medicine, Oral Oncology and Oral Surgery at the Catholic University of Portugal, where he was also Clinical Director of the University Dental Clinic, Director of the Integrated Master in Dental Medicine and Director of Specialized Master's Degree in Oral and Maxillofacial Medicine and Pathology. He was also Visiting Clinical Associate Professor at the University of Michigan until 2014. In August 2015, he left these positions for a position at Case Western Reserve University. He is also a researcher at the "Centre for Research in Higher Education Policies".
Additional affiliations
July 2020 - present
Center for Health Technology and Services Research (CINTESIS)
Position
  • Senior Researcher
January 2017 - present
September 2012 - August 2015
Universidade Católica Portuguesa
Position
  • Head of the Post-Graduation Program in Oral and Maxillofacial Pathology
Education
January 2008 - April 2011
Vrije Universiteit Amsterdam
Field of study
  • Oral and Maxillofacial Surgery/Pathology

Publications

Publications (79)
Article
Introduction: The way students process and organize information to facilitate learning is known as learning style. Knowing one's learning style can improve learning and help teachers choose their teaching methods more effectively. This study was conducted to investigate different scoring methods of the VARK questionnaire and compare different lear...
Presentation
Full-text available
The geopolitics of the third mission – Dominant discourses in a Southern European Country
Article
Full-text available
Higher Education Institutions (HEIs) play a crucial role in knowledge society by providing and disseminating knowledge. In this regard, academics have been encouraged to collaborate with society, leading to the emergence of new modes of knowledge production. Several institutional and individual factors have been identified as determinants of the ac...
Preprint
India is at the 3rd position worldwide in terms of publication of scientific literature. However, in terms of productivity, it has been consistently failing to transform the research knowledge into industrial output. This study compares India with the leading countries to understand its lacuna in terms of R&D policy and outputs. Although scientific...
Article
Potentially malignant disorders are one of the clinical challenges. Dysplasia in these lesions can be a predictor of more potential for malignant changes. Photo‐bio‐modulation in benign lesions has advantages but there is doubt on its safety in potentially malignant lesions. This study aims to assess if low‐level‐laser can promote dysplastic change...
Article
Full-text available
Objectives To assess changes in the maxillary sinus (MS) and pharyngeal airway space (PAS) after bimaxillary orthognathic surgery using cone-beam computed tomography (CBCT). Materials and Methods The CBCT scans of 48 patients were divided into two groups: group 1: maxillary advancement and mandibular setback (n = 24); group 2: maxillomandibular ad...
Article
Full-text available
The COVID‐19 pandemic has had an immediate and dramatic impact on dental education. The Association of Dental Education in Europe decided to carry out an investigation to assess the immediate response of European Academic Dental Institutions. An online survey was sent to both member and non‐member dental schools to investigate the impact on non‐cli...
Article
Full-text available
Purpose: To provide guidance regarding best practices in the prevention and management of medication-related osteonecrosis of the jaw (MRONJ) in patients with cancer. Methods: Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) and ASCO convened a multidisciplinary Expert Panel to evaluate t...
Article
Aims This study aims to characterize the hygiene habits, the self‐perception of the need for treatment and the oral condition of a population with a disability. Methods and Results This research is part of an observational, cross‐sectional epidemiological study on oral health and quality of life of people with mild intellectual disabilities living...
Article
Full-text available
Skeletal complications caused by osteoporosis or bone metastases are associated with considerable pain, increased mortality, and reduced quality of life. Furthermore, such events place a burden on health care resources. Agents that prevent bone resorption, such as bisphosphonates or denosumab, can reduce the risk of skeletal-related events and are...
Article
Background The purpose of this study is to develop a Portuguese version of the Oral Health Impact Profile (OHIP-14) and validate it for people with mild intellectual disability (OHIP-14-MID-PT). Methods The Portuguese version of the questionnaire was drawn up from the original English version, following internationally defined guidelines. Intervie...
Article
Individuals with disabilities are regarded as a highly vulnerable population group, particularly as far as oral health is concern. However, few studies have assessed the impact of the oral condition on the quality of life of these individuals. Therefore, the aim of this study is to expand knowledge on the oral health status of the Portuguese adults...
Data
Clinical Oral Health Index (COHI); Clinical Oral Care Needs Index (COCNI) and Clinical Oral Prevention Index (COPI). (PDF)
Data
OHIP-14-MID-PT (Portuguese version of the Oral Health Impact Profile adapted to people with mild intellectual disabilities). (PDF)
Article
A 64-year-old institutionalised woman presented to our clinic for the management of black hairy tongue. Despite the predictable outcome in treating this disease, this case presents multiple challenges such as the patients' cognitive impairment, her family dynamics, social factors and the health system as a whole, that makes it difficult to treat. ©...
Chapter
As e-healthcare becomes a reality for healthcare service provision across the world, challenges in acceptance, implementation, usage and effectiveness have begun to emerge. The infrastructure, readiness and literacy levels required for the effective delivery of e-healthcare services may be prohibitive in providing access to those most in need. As r...
Book
The development of better processes to provide proper healthcare has enhanced contemporary society. By implementing effective collaborative strategies, this ensures proper quality and instruction for both the patient and medical practitioners. Health Care Delivery and Clinical Science: Concepts, Methodologies, Tools, and Applications is a comprehen...
Chapter
With the expanding utilization of digital and technological media by public health providers and healthcare consumers, there is a need to evaluate the patients' role. There is good evidence of the growing acceptability of the Internet in seeking health information. This paper aims to evaluate the patients' role as an informed-patient. This role, al...
Book
The prevention and treatment of diseases is a primary concern for any nation in modern society. To maintain an effective public health system, procedures and infrastructure must be analyzed and enhanced accordingly. Public Health and Welfare: Concepts, Methodologies, Tools, and Applications provides a comprehensive overview of the latest research p...
Article
Objective: Oral mucositis (OM) is a common complication of chemotherapy and radiotherapy. The aim of this study was to evaluate the effects of treating 5-fluorouracil-induced OM with apigenin and dexamethasone. Methods: Thirty-six male Syrian hamsters were randomly assigned to one of three groups: control (50% acetic acid + 5-FU), 50% acetic aci...
Article
Full-text available
A 30-year-old woman presented for orthodontic treatment, with a chief symptom of a ‘shifting bite’ and concurrent facial asymmetry with aesthetic concerns. The patient had previously received treatment from several general dentists and several specialists, without accurate diagnosis. Radiological investigation coupled with biopsy confirmed a diagno...
Article
Full-text available
Purpose: To date, no ideal strategy has been established for treating or preventing medication-related osteonecrosis of the jaw (MRONJ). The aim of the present work was to perform a systematic literature review to determine the efficacy of autologous platelet concentrate (APC) application, for prevention or treatment of MRONJ, together with surgic...
Article
There are several novel anticoagulant agents that are being increasingly used as an alternative to warfarin, with these drugs being reported to be at least as effective if not better. Their increased use means that oral care clinicians should have a sound understanding of the mechanism of action, pharmacology, reversal strategies and management of...
Article
The association between chronic inflammatory disorders and oral carcinogenesis has been both a source of interest and contention. Based upon its central importance in oral carcinogenesis, the finding that the PI3k/Akt/mTOR pathway is activated in oral lichen planus, chronic graft-versus-host disease, and chronic oral candidiasis suggests that it ma...
Article
Over the years, genomics has become an increasingly important - not to say key - scientific domain with regards to the development of knowledge in areas so important such as oncology, further upholding that the histological ubiquity of squamous cell carcinomas of the mouth seem to rely on their diverse molecular and genetic characteristics. This ar...
Conference Paper
Full-text available
Introduction Permanent maxillary canines are, after third molars, the teeth most often found impacted, usually with a palatal presentation. Clinical case A female patient, 47-years-old, ASA I, non-smoker, was observed in the Oral Surgery Clinic of the Catholic University of Portugal. During the clinical and radiological examination we found an imp...
Article
With the expanding utilization of digital and technological media by public health providers and healthcare consumers, there is a need to evaluate the patients' role. There is good evidence of the growing acceptability of the Internet in seeking health information. This paper aims to evaluate the patients' role as an informed-patient. This role, al...
Article
As e-healthcare becomes a reality for healthcare service provision across the world, challenges in acceptance, implementation, usage and effectiveness have begun to emerge. The infrastructure, readiness and literacy levels required for the effective delivery of e-healthcare services may be prohibitive in providing access to those most in need. As r...
Article
Purpose Envision of tissue change during carcinogenesis has evolved in recent years. From a clinical standpoint, the new paradigms tend to shift from the clinically identifiable lesion per si, to other parameters such as “field” changes involving genetically and epigenetically altered cells within a tissue. Materials and methods A review of the li...
Article
Introduction The overall incidence of cancer has increased substantially over the last decades. The oral cavity is one of the locations where side effects usually occur, namely mucositis, changes in salivary glands, rampant caries, bleeding caused by blood dyscrasias, osteoradionecrosis and osteochemonecrosis. Purpose To assess the main oral manif...
Conference Paper
Full-text available
A candidíase oral é uma infecção micótica oportunista, comum na cavidade oral, causada pela proliferação anormal de Candida, sendo a mais comum a Candida albicans. Estes microrganismos são comensais do tracto gastrointestinal, vaginal e pele, estando presentes em 20-50% da população dentada saudável. As espécies Candida non-albicans, têm vindo a au...
Data
Poster seleccionado para Comunicação Oral nas VI Jornadas de Medicina Dentária da UCP-CRB Viseu
Article
Oral Diseases (2011) 17 (Suppl. 1), 7–22 Squamous cell carcinoma (SCC) of the oral and oropharyngeal region is the sixth most common malignancy in the world today. Despite numerous advances in treatment, long-term survival from this disease remains poor. Early detection can decrease both morbidity and mortality associated with this neoplasm. Howeve...
Article
The aim of the present study was to investigate the association between the expression of cyclooxygenase-2 (COX-2) in keratocystic odontogenic tumors (KCOT) and more commonly used markers, such as p53 and Ki-67. Expression of cyclooxygenase-2 (COX-2) in 20 biopsy specimens of keratocystic odontogenic tumors (KCOT) has been analyzed and compared wit...
Book
Full-text available
Rehabilitation of edentulous spaces with fixed dentures are often the patient’s first option1. Occasionally, combined implant and orthodontic treatment may be required
Article
J Oral Pathol Med (2010) 40: 497–503 There is increasing evidence that overexpression of cyclooxygenase-2 (COX-2) plays an important role in tumour growth and spread of tumours by interfering with cell proliferation, cellular adhesion, immune surveillance, apoptosis, and angiogenesis. COX-2 levels are increased in various tumours. In this study, th...
Article
The recurrence rate in conservative surgical treatment, without adjunctive treatment, of the keratocystic odontogenic tumor (KCOT) has been studied. A total number of 68 patients, previously untreated and fulfilling the histopathological criteria provided by the 2005 WHO classification, has been retrospectively reviewed. The study period lasted fro...
Article
Keratocystic odontogenic tumor (KCOT), formerly referred to as odontogenic keratocyst, is a benign neoplasm of odontogenic origin which may present an aggressive and infiltrative behavior leading to high recurrence rates. A review of the various treatment modalities, ranging from simple enucleation to radical surgery is portrayed in relation to cli...
Article
In the classification of Head and Neck Tumors, published in 2005 by the World Health Organization Classification, the odontogenic keratocyst has been reclassified as a benign intraosseous neoplasm, calling it "keratocystic odontogenic tumor" (KCOT). Significant differences on the molecular level between KCOT and other odontogenic cystic lesions sug...
Article
s u m m a r y Cyclooxygenase-2 (COX-2) levels are increased in various tumors, particularly those involving the esoph-agus, stomach, breast, pancreas, lung, colon, skin, urinary bladder, prostate and head and neck. Neverthe-less, the tumorigenic mechanisms of COX-2 overexpression still remain poorly understood and may include mechanisms that may ac...
Article
Oromandibular dystonia (OMD) is a rare neurological condition infrequently seen by oral and maxillofacial surgeons which may result in inappropriate deviation of the mandible, subluxation and intraoral soft tissue trauma. A case is presented of a patient suffering from spasmodic torticollis and lateral pterygoid dystonia and currently under treatme...
Article
Full-text available
Bisphosphonates are synthetic analogs of inorganic pyrophosphate, which are not only potent inhibitors of osteoclast-mediated bone resorption, but also present an important inhibitory activity of angiogenesis. Bisphosphonates become, since 1996, the standard of care in the management of patients with osteoporoses as well as bone metabolism alterati...
Article
Full-text available
Bisphosphonates are synthetic analogs of inorganic pyrophosphate, which are not only potent inhibitors of osteoclast-mediated bone resorption, but also present an important inhibitory activity of angiogenesis. Bisphosphonates become, since 1996, the standard of care in the management of patients with osteoporoses as well as bone metabolism alterati...
Article
An asymptomatic radiolucency between a vital 44 and 45 was detected in a 64-year-old woman. Treatment consisted of enucleation. Histopathologically, the features of a lateral periodontal cyst were observed. The lateral periodontal cyst is a rather rare developmental odontogenic cyst that has a tendency to recur after incomplete removal.
Article
Full-text available
The lateral periodontal cyst and the botryoid odontogenic cyst are two rare nosological entities, who, despite their radiological and clinical presentation can only be diagnosed by their rather typical histopathological characteristics. The purpose of this article is to report two cases of radiolucent cystic lesions of the mandible, located in the...
Article
Full-text available
Autotransplantation of mandibular third molars in a precocious phase of development is indicated when a substitute for adjacent compromised or missing molars is needed, and when mesial movements of the posterior teeth, the resultant loss of space, and overeruption of opposing teeth and consequent changes in the occlusion must be avoided. Provided t...

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