Rüstem Keçili

• PhD
• Anadolu University

Molecularly imprinted polymers are one of the emerging tools of analytical chemistry, which have been widely studied as sorbents for the extraction of pharmaceuticals from various matrices. The process of greenification could be applied in different aspects, from using green monomer, choosing a less hazardous template, using green solvents, and com...

In response to the alarming rates of zolpidem abuse, this study presents a pioneering approach utilizing molecularly imprinted nanoparticles (MIPs) in conjunction with high‐performance liquid chromatography (HPLC) for the selective detection of zolpidem. The rational choice of zolpidem as the target analyte stems from its widespread misuse and clin...

There is a trend in analytical chemistry towards development of eco-friendly methods of sample preparation without loss of efficiency. This book provides a general, critical, and updated vision of the different green sample preparation approaches that have been developed. These include miniaturisation of the extraction techniques that allow a reduc...

There is a trend in analytical chemistry towards development of eco-friendly methods of sample preparation without loss of efficiency. This book provides a general, critical, and updated vision of the different green sample preparation approaches that have been developed. These include miniaturisation of the extraction techniques that allow a reduc...

Bu çalışmada, Eskişehir ili sınırları içerisinde bulunan ve ülkemiz açısından ekonomik değeri oldukça yüksek olan bastnasit cevherinde bulunan Barit (BaSO4) mineralinin flotasyon tekniği ile seçici olarak cevherden ayırımı ve yüksek saflıkta barit elde edilmesi amaçlanmıştır. İlgili bölgeden tekniğe uygun olarak alınan cevher numunesi kırıtıcı-öğüt...

Recent years have been associated with the development of various sensor-based technologies in response to the undeniable need for the rapid and precise analysis of an immense variety of pharmaceuticals. In this regard, special attention has been paid to the design and fabrication of sensing platforms based on electrochemical detection methods as t...

The detection of various hazardous compounds (i.e., pesticides, heavy metals and pharmaceuticals etc.) in food, biological and environmental samples is crucial for food safety, clinical studies and environmental analysis. Main drawbacks of the analytical techniques towards these compounds are selectivity, efficiency, total cost of the analysis and...

Metal-organic frameworks (MOFs) have emerged as porous hybrid materials composed of metal ions and organic ligands. MOFs have attracted the attention of many researchers due to their promising characteristics, including high porosity, surface area, and drug loading capacity, tunable pore size and structure, good biodegradability and biocompatibilit...

The huge amounts of plastic production (millions of tons) are carried out all around world every year and EU is one of the biggest consumers of these products. In 2021, recycling rate of plastic wastes around 32.5% in the EU and the rest end up on their journey in landfills and oceans that lead to environmental pollution which is a crucial global c...

Modern Environmental Analysis Techniques for Pollutants presents established environmental analysis methods, rapidly emerging technologies, and potential future research directions. As methods of environmental analysis move toward lower impact, lower cost, miniaturization, automation, and simplicity, new methods emerge and ultimately improve the ac...

Yeşil kimya, kimyasal proseslerde çevreye, doğaya ve bütün canlı varlıklara karşı yol açan zararların minimuma düşürülmesini ve hatta tamamen ortadan kaldırılmasını amaçlayan araştırmaların gerçekleştirildiği, son zamanlarda araştırmacılardan büyük ilgi gören önemli alanlardan biridir. Moleküler baskılanmış polimerler ise, karmaşık bir matrikste (b...

Lab-on-a-chip devices have now-a-days become an important aspect of analytical/bioanalytical chemistry having wide range of applications including clinical diagnosis, drug screening, cell biology, environmental monitoring, food safety analysis etc. Conventional lab-on-a-chip devices generally employ chemicals that are not environmentally friendly a...

Corrosion causes permanent damage to metal surfaces and is a major global challenge, spanning numerous fields including industrial sectors, construction materials, and surface treatments for metallic cultural heritage preservation. Nanomaterials and nanocomposites can be used as effective alternative corrosion inhibitors in the place of traditional...

Environmental pollution and its drastic effects on human and animal health have urged governments to implement strict policies to minimize damage. The first step in applying such policies is to find reliable methods to detect pollution in various media, including water, food, soil, and air. In this regard, various approaches such as spectrophotomet...

Bulk and magnetic core-shell Molecularly Imprinted Polymers (MMIPs) have been introduced and compared to extract and determine amiodarone from a complex matrix, i.e., plasma, due to the importance of Therapeutic Drug Monitoring (TDM). Polymer synthesis was confirmed by FTIR, AFM, TGA, DLS, VSM, TEM, and the adsorption studies such as capacity, isot...

Conductive polymers as composite materials have been attracted tremendous attention due to their versatile and excellent features such as tunable conductivity, facile synthesis and fabrication, high chemical and thermal stability etc. These characteristics make them versatile and let them being used in numerous fields including microelectronics, op...

MXene belongs to a newly emerged family of two-dimensional (2D) stacked layered materials consisting of early transition metal carbides and/or nitrides. The intriguing features of MXene such as metallic conductivity, biocompatibility, large surface area, hydrophilicity and 2D layered atomic structure with abundant highly active surface sites make i...

Misusing or overusing antibiotics in livestock and poultry can result in the accumulation of mentioned drugs in the animal meat. Consequently, its consumption by humans and therefore increasing the risks of antibiotic resistance emergences. In order to decrease these risks, constant monitoring of the meat samples is necessary. Therefore, the concen...

Metal-organic frameworks (MOFs) are a group of porous crystalline materials which have gained considerable attention in the past few years due to their exceptional characteristics including ultrahigh surface area/porosity, tunable particle/pore size, versatile structures/morphologies, as well as biocompatibility. The combination of all these featur...

The rapidly growing existence of a number of contaminants (i.e. heavy metals, dye compounds, explosives and pesticides etc.) in environment is an alarming concern not only due to their harmful impacts for the environment bur also due to their potential high risk for human health. Thus, the careful and sensitive detection of these environmental cont...

Magnetic nanoparticles (MNPs) uniquely combine superparamagnetic performance with dimensions that are smaller than or similar size to molecular analytes. Recently, functionalized MNPs are predicted to be a driver for technology and business in this century and hold the promise of high performance materials that will significantly influence all aspe...

Polymeric micelles (PMs) are one of Nanoscale delivery systems with high stability, loading capacity, and biocompatibility. PMs are nano-sized and spherical particles with a hydrophilic shell and hydrophobic core or reverse depending on their applications. Polymeric micelles could be synthesized by different methods, such as direct dissolution, dia...

Materials in nanodimensions such as magnetic nanoparticles exibit fascinating physico-chemical features (i.e. high surface area, very small size, superparamagnetism, active surface which can be successfully functionalized, low toxicity, etc). Because of these superior features, functionalized magnetic nanoparticles received increasing attention for...

Green miniaturized technologies are the need of the hour which not only facilitates the downscaling of conventional analytical or bioanalytical systems but also serves as the driving force towards safeguarding our environment from toxic and harmful chemicals. Additionally, the rapid advancements in the microfabrication and nanofabrication approache...

Sample Preparation with Nanomaterials: Next Generation Techniques for Sample Preparation delivers insightful and complete overview of recent progress in the use of nanomaterials in sample preparation. The book begins with an overview of special features of nanomaterials and their applications in analytical sciences. Important types of nanomaterials...

Micro total analysis systems (µTAS) which have received great interest in the recent years and successfully employed for fluid processing in microchannels at microliter levels are powerful alternatives to traditional macroscale analytical systems. Unique benefits arise in the scaling down of traditional macroscale systems, including significant dec...

The existence of nanomaterials (NMs) in the air and water can display crucial impacts on the environment and humans. The extensive employment of NMs in industrial applications will inevitably cause the release of NMs into the environment. Accurately, monitoring techniques of NMs are really important to their mobility, reactivity, ecotoxicity, and p...

Recently, different types of magnetic nanomaterials (NMs) including nanoparticles have been used as the sample preparation supporting materials. The utility of unique optical, magnetic, thermal, and mechanical properties of magnetic NMs has added a new dimension to their applications. Magnetic NMs can convert dissipated magnetic energy into thermal...

New special properties of nanomaterials (NMs) fascinated new technologies in sample preparation tools and device fabrication. Day by day, various research chemists and material scientists are continuously exploring these. NMs have exotic properties such as temperature dependence of resistivity, spin resonance spectra, and magnetic susceptibility me...

Lab‐on‐a‐chip (LOC) platforms are excellent tools for sample analysis and treatment with interest for DNA, protein, and cells studies or diagnostics due to benefits such as the reduced sample volume, low cost, portability, and the possibility to build new analytical devices or be integrated into conventional ones. These platforms have advantages of...

Extensive applications of nanomaterials (NMs) can considerably increase their release to the environment, through air, groundwater, and soil. NMs may enter the environment in the course of their lifecycle and can be toxic, which increases their risk. In the case of release to the environment, the special properties of NMs can result in undesired ef...

The design, development, and application of nanomaterials (NMs) are rapidly progressing. As nanotechnologies mature, a broad spectrum of NMs can be successfully applied for increasingly growing different application fields. The release of NMs to the environment and exposure of human populations and natural biota are inevitable. Moreover, NMs and th...

Surface‐Enhanced Raman Spectroscopy (SERS) is a powerful technique that is successfully employed to measure the vibrational fingerprint of an analyte based on the inelastic light scattering from the sample. Nanomaterials (NMs) have contributed in SERS's sample preparation, as these materials are used in designing and preparing novel substrates for...

In this chapter, design, preparation, and various applications of nanomaterials (NMs) in analytical sciences will be presented. Because of the intensive and multidisciplinary research carried out in the past years on NMs, the scientific community understands nowadays much better the chemistry, structure, and properties of these interesting material...

Sample preparation is of vital importance for biological samples due to high complexity of these samples. The fast advancements in the design and synthesis of novel nanomaterials (NMs) with different compositions, morphologies, and proper surface modifications enable a category of powerful tools for the sample preparation for biological samples. Th...

Nanomaterials (NMs) have attracted great attention in numerous fields of materials science, electronics, biology, and even medical sciences. Sample preparation is the heart of the environmental management as it provides ways to detect the environmental pollutants, which is normally used to implement and establish environmental legislations. The rec...

Nanomaterials (NMs) have exceedingly significant surface‐to‐volume ratio and quantum effects due to their nanoscale size as compared to conventional materials. Their physical and chemical properties, including thermal, mechanical, electronic, catalytical, biological, and optical properties, would be significantly changed or improved and making them...

The global market for nanomaterials (NMs) has been expanding rapidly, and the numbers of workers employed directly by the NM sector are estimated to strongly increase in the future. Analysts are predicting explosive economic growth in the sector over the coming years. Currently, the market is led by classical materials that have been in use for man...

Sampling and sample preparation are challenging tasks in the analytical processes. Therefore, the design and development of efficient, easy, fast, cheap, and environmentally friendly sampling and sample preparation techniques are a crucial issue before the analysis of target compound(s). On the other hand, miniaturization is a rapidly growing trend...

Nanomaterials exhibit excellent properties such as great chemical and physical stabilities, lower density, and large surface area. These excellent properties of nanomaterials make them popular candidates for the design and development of novel functional nanomaterial‐based membranes. The combination of membranes with the unique properties of nanoma...

The recognition and detection of proteins has an important role in the fields of biochemistry and medicine in term of diagnosis and prognosis. In this study, molecularly imprinted cryogel (MIP) was synthesized for the selective recognition of Cytochrome-c (Cyt-c) by cryopolymerization techniques with the lanthanide-chelate approach using (MAAP)2-Ce...

This research aims to design, preparation, and characterization of molecularly imprinted polymeric particles embedded-cryogels for the selective removal of potentially genotoxic impurities 2-ami-nopyridine and 5-amino-2-chloropyridine in model active pharmaceutical ingredients piroxicam and tenoxicam. For this purpose, aminopyridines imprinted poly...

Molecularly imprinted polymers (MIPs) are highly selective polymeric materials that mimic the shape-specific binding mechanism, which is found naturally occurring in the biological structures (i.e., 3-D binding site of an enzyme, or the glycoprotein recognition sites in antibodies). However, since they are designed and prepared from artificial poly...

Smartphones are emerging as potential replacements for the instrumentation involved in performing various sensing applications such as fast diagnostic tests. This is fueled in part by the gradual increase of billions of smartphone users (∼ 3.5 billion users in 2020) even in low-income countries. In this chapter, the latest advancements on the desig...

The emergence of the smartphone technology led to so many changes in everyone’s life from communicating each other to online shopping and entertainment and studying etc. On the other hand, this technology also provided new opportunities and applications in different fields of science. This chapter presents an overview of the design, fabrication and...

The rapidly growing numbers of the smartphone users (~ 3.5 billion in 2020) drives the fast advancements of the smartphones and their integrated parts into other analytical systems for the design and fabrication of next-generation imaging, sensing, diagnostics and measurement platforms. The high number of smartphone users gradually drives the fast...

A novel analytical method, based on high-performance liquid chromatography with a UV (HPLC-UV) detection system for the sensitive detection of a genotoxic impurity (GTI) 5-amino-2-chloropyridine (5A2Cl) in a model active pharmaceutical ingredient (API) tenoxicam (TNX), has been developed and validated. The HPLC-UV method was used for the determinat...

Because of the limited performance of conventional bulk-scale materials, the development of novel materials in nanoscale with enhanced properties has attracted increasing great attention of research from different fields of science. Significance progresses were made in nanotechnology and nanoscience in the past years. Compared with conventional mat...

The process of matrix clean-up and extraction of analytes has a significant influence on the detection and determination of the analyte, especially in trace amounts. Molecularly imprinted polymers (MIPs) are solid particles that can absorb specific molecules regarding the template molecule used in the synthesis process of each type of MIP. As a res...