Rudi Klein

Rudi Klein
Victoria University Melbourne | VU · College of Health and Biomedicine

Doctor of Philosophy

About

41
Publications
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Introduction
Skills and Expertise

Publications

Publications (41)
Article
In 2018, Victoria University adopted a new teaching delivery model, now known as the Block Teaching Model (BTM). The aim of this study focuses on how this new approach to teaching has impacted student learning and academic success in particular from students who come from a disadvantaged background, compared with those who come from a non-disadvant...
Article
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During semester one of 2020, the units ‘Functional Anatomy of the Trunk’ and ‘Functional Anatomy of the Limbs’ which focus on human topographical anatomy were re-designed into an online delivery format and taught remotely in response to the COVID-19 lockdown. It was expected that the move to remote teaching would negatively impact student perceptio...
Article
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This study examines the impact on academic success of two different models of teaching for repeating students. Students who failed in 2017 under the traditional model of teaching, involving a 12 week semester with lectures and tutorials, were exposed the following year to the newly introduced “block model” of teaching, whereby students study one un...
Article
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This study examines the use of three computer programs designed for the study of gross anatomy; An@tomedia Online, AnatomyTV, and Thieme, as in-class learning support programs within the newly adopted “Block model” of teaching delivery at Victoria University. Victoria University is the first and only Australian university to have introduced a block...
Article
Full-text available
Bioscience is a foundational unit (subject) of undergraduate allied health degree programs, providing students the scientific basis underpinning their clinical practice. However, despite its significance, bioscience is a difficult academic hurdle for many students to master. The introduction of active learning strategies, including small team-based...
Article
Cardiovascular disease remains a burden for Westernized countries. Peptide YY (PYY) raises blood pressure, yet its role has not yet been determined in diseased arteries. This study was aimed at identifying PYY and eNOS in diseased blood vessels and to determine which blood vessels respond to PYY. New Zealand White rabbits were fed an atherogenic di...
Article
The present study investigated the effect of acute thermal stimulation in conscious rats on the production of Fos, a marker of increased neuronal activity, in spinally projecting and nitrergic neurons in the hypothalamic paraventricular nucleus (PVN). The PVN contains a high concentration of nitrergic neurons, as well as neurons that project to the...
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Aging generally results in muscle and bone atrophy, with accelerated loss in the first few years after menopause contributing to decline in strength, balance, and mobility. This investigation compared the effects of 1 of year periodized highintensity strength training on a group of less-than-5-years (LF) postmenopausal women (n = 10, mean age 51 ye...
Article
Eight competitive oarswomen (age, 22 +/- 3 years; mass, 64.4 +/- 3.8 kg) performed three simulated 2,000-m time trials on a rowing ergometer. The trials, which were preceded by a 24-hour dietary and training control and 72 hours of caffeine abstinence, were conducted 1 hour after ingesting caffeine (6 or 9 mg á kg-1 body mass) or placebo. Plasma fr...
Article
To investigate the effect of caffeine ingestion on short-term endurance performance in competitive rowers. In this randomized double-blind crossover study, eight competitive oarsmen (peak oxygen uptake [VO2peak] 4.7+/-0.4 L x min(-1), mean +/- SD) performed three familiarization trials of a 2000-m rowing test on an air-braked ergometer, followed by...
Article
To determine whether high-volume, high-impact physical training in prepubertal and early pubertal male gymnasts is associated with reduced statural and segmental growth and reduced serum insulin-like growth factor-I (IGF-I) and increased cortisol (C) levels. Height, sitting height, leg length, and segmental lengths (humerus, radius, femur, and tibi...
Article
Short stature in competitive prepubertal and early pubertal male gymnasts: The result of selection bias or intense training? Robin M. Daly, PhD, Peter A. Rich, PhD, Rudi Klein, PhD, and Shona L. Bass, PhD As more children become involved in intense physical training, concern has increased regarding potential risks to linear growth and final adult s...
Article
Physical activity has been proposed as one strategy to enhance bone mineral acquisition during growth. The aim of this study was to determine whether frequent impact loading associated with gymnastics training confers a skeletal benefit on pre- and peripubertal male gymnasts. We measured broadband ultrasonic attenuation (BUA, dB/MHz) at the calcane...
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Full-text available
The effects of performing intensive training during growth remains controversial, with claims of negative effects upon growth and maturation purportedly due at least in part to a combination of hormonal disturbances and inappropriate nutrition. We examined the training-related responses of total testosterone (T), insulin-like growth factor-1 (IGF-1...
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Full-text available
Effects of High-Impact Exercise on Ultrasonic and Biochemical Indices of Skeletal Status: A Prospective Study in Young Male Gymnasts ROBIN M. DALY,1 PETER A. RICH,1 RUDI KLEIN,1 and SHONA BASS2 ABSTRACT Physical activity has been proposed as one strategy to enhance bone mineral acquisition during growth. The aim of this study was to determine whet...
Article
Full-text available
The e€ffects of performing intensive training during growth remains controversial, with claims of negative e€ects upon growth and maturation purport-edly due at least in part to a combination of hormonal disturbances and inappropriate nutrition. We examined the training-related responses of total testosterone (T), insulin-like growth factor-1 (IGF-...
Article
Full-text available
Evidence suggests that weight-bearing exercise during the growing years may enhance peak bone mass. The purpose of this study was to compare ultrasound bone measurements, serum alkaline phosphatase (S-ALP), serum osteocalcin (S-OC), and dietary calcium in highly active and normal healthy male children. Subjects were 33 elite and subelite male gymna...
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Full-text available
Influence of High Impact Loading on Ultrasound Bone Measurements in Children: A Cross-Sectional Report R. M. Daly, P. A. Rich, R. Klein Abstract. Evidence suggests that weight-bearing exercise during the growing years may enhance peak bone mass. The purpose of this study was to compare ultrasound bone measurements, serum alkaline phosphatase (S-ALP...
Article
Full-text available
Evidence suggests that weight-bearing exercise during the growing years may enhance peak bone mass. The purpose of this study was to compare ultrasound bone measurements , serum alkaline phosphatase (S-ALP), serum os-teocalcin (S-OC), and dietary calcium in highly active and normal healthy male children. Subjects were 33 elite and subelite male gym...
Article
Plasma follistatin (FS) concentrations were determined after castration ( n =5) or sham castration ( n =4) of mature rams. Both treatments resulted in a prolonged increase in FS between 7 and 19 h after surgery, which returned to pretreatment concentrations by 24 h. Tumour necrosis factor-α (TNF-α), a sensitive marker of an acute-phase response, wa...
Article
1. The effect of inflammation induced by lipopolysaccharide (LPS) injection on plasma follistatin (FS) concentrations was investigated. 2. Plasma FS and tumour necrosis factor-α concentrations increase following LPS administration in ewes. 3. The rise in FS is similar, but more sustained, to that previously observed after surgery. 4. These results...
Article
The aims of this study were to determine the plasma concentrations of follistatin in rams and to assess if the testis contributes to circulating follistatin and if there is uptake or production of follistatin by the head in rams. Catheters were inserted in the carotid artery, jugular vein and spermatic vein of intact rams during the non-breeding se...
Article
Unlabelled: This study examined the effects of the anticoagulant heparin on plasma follistatin (FS) concentrations used during blood sampling in Corriedale ewes. Plasma FS concentrations increased acutely (P < 0.01) following a bolus intravenous injection of heparin (3200 U). To determine whether frequent sampling per se can also increase plasma F...
Article
A sensitive and specific heterologous radioimmunoassay for FSH-suppressing protein (FSP or follistatin) was applied to ovine plasma. Following a logit–log dose transformation, parallel dose–response lines were observed between purified bovine 35 kDa FSP used as standard and serial dilutions of ewe plasma. Activin-A, inhibin-A and a range of other p...
Article
This review focuses on the role of the inhibin-related peptides, inhibin, activin, follistatin and α-N, in the hormonal regulation of reproduction, using data from the sheep, cow, pig and rat. Emphasis is placed on recent advances and remaining gaps in knowledge of the roles of these substances. The evidence confirms a role for inhibin as a circula...
Article
A RIA for bovine (b) FSH-suppressing protein (FSP) was developed using an antiserum raised in a rabbit to purified 39-kDa bFSP, iodinated 35-kDa FSP as tracer, and purified 35-kDa bFSP as standard. Purified 35-kDa FSP was iodinated using the iodogen procedure, and the iodinated FSP was purified by dye affinity chromatography. After a logit log-dose...
Article
A series of daily injections of beta very low density lipoprotein (beta-VLDL) was administered over 4-5 days to rabbits whose arteries contained either experimental circumferential lesions or areas of intimal thickening. The circumferential lesions were similar to those that occur spontaneously and were produced by the application of longitudinal t...
Article
Three proteins (31, 35 and 39 kDa) with inhibin-like activity have been isolated from bovine follicular fluid with identical NH2-terminal amino acid sequences. These polypeptides are distinct from inhibin, based on their different NH2-amino acid sequence, molecular masses, absence of a subunit structure, absence of inhibin immunoactivity and the fa...

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