Roselyne Chauvin

Roselyne Chauvin
Washington University in St. Louis | WUSTL , Wash U · Department of Neurology

Post doc in neuroimaging

About

29
Publications
2,453
Reads
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306
Citations
Citations since 2016
29 Research Items
304 Citations
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Publications

Publications (29)
Preprint
Full-text available
Primary motor cortex (M1) has been thought to form a continuous somatotopic homunculus extending down precentral gyrus from foot to face representations 1,2 . The motor homunculus has remained a textbook pillar of functional neuroanatomy, despite evidence for concentric functional zones ³ and maps of complex actions ⁴ . Using our highest precision...
Article
Full-text available
Due to a tracking error during the peer review process, this article was published with the wrong received date. This article was received 19 May 2021, not 20 August 2020. Further, this article was originally published under the standard Springer Nature license (© The Author(s), under exclusive licence to Springer Nature Limited). It is now availab...
Article
Science and art have been intertwined for centuries, as both embody means for humans to represent, communicate, and interpret our external and internal worlds. The collective effort to gather and organize knowledge about the brain blends well with a wide array of human creative activities, from visual and performing arts to interactive media. It th...
Article
Full-text available
Magnetic resonance imaging (MRI) has transformed our understanding of the human brain through well-replicated mapping of abilities to specific structures (for example, lesion studies) and functions1–3 (for example, task functional MRI (fMRI)). Mental health research and care have yet to realize similar advances from MRI. A primary challenge has bee...
Article
Full-text available
Patients with attention-deficit/hyperactivity disorder (ADHD) often develop early onset substance use disorder (SUD) and show poor treatment outcomes. Both disorders show similar reward-processing alterations, but it is unclear whether these are associated with familial vulnerability to SUD. Our aim was to investigate effects of family history of S...
Preprint
Full-text available
Background Autism spectrum disorder (autism) is a complex neurodevelopmental condition with pronounced behavioural, cognitive, and neural heterogeneities across individuals. Here, our goal was to characterise heterogeneity in autism by identifying patterns of neural diversity as reflected in BOLD fMRI in the way individuals with autism engage with...
Preprint
Full-text available
Neuroimaging studies on functional connectivity (FC) in autism have been hampered by small sample sizes and inconsistent findings with regard to whether connectivity is increased or decreased in individuals with autism, whether these alterations affect focal systems or reflect a brain-wide dysfunction, and whether these are age- and/or sex-dependen...
Article
Full-text available
Background: Attention-deficit hyperactivity disorder (ADHD) is associated with white matter (WM) microstructure. Our objective was to investigate how WM microstructure is longitudinally related to symptom remission in adolescents and young adults with ADHD. Methods: We obtained diffusion-weighted imaging (DWI) data from 99 participants at two ti...
Preprint
Science and art have been intertwined for centuries, both representing means for humans to represent, communicate and interpret our external and internal worlds. Our collective effort to gather and organize knowledge about the brain blends well with a wide array of human creative activities, from visual and performing arts to interactive media. It...
Article
Full-text available
Patients with attention-deficit/hyperactivity disorder (ADHD) are often diagnosed with comorbid substance misuse (SM), which is associated with poor treatment efficacy. Although literature indicates similar inhibitory control deficits in both conditions, it is unclear whether SM in ADHD exaggerates pre-existing deficits, with additive or distinct i...
Article
Full-text available
Attention-deficit/hyperactivity disorder (ADHD) is associated with altered functioning in multiple cognitive domains and neural networks. This paper offers an overarching biological perspective across these. We applied a novel strategy that extracts functional connectivity modulations in the brain across one ( P single ), two ( P mix ) or three ( P...
Article
Attention-Deficit/Hyperactivity Disorder (ADHD) and Substance Use Disorder (SUD) often co-occur and are associated with treatment resistance. Both disorders are characterized by similar reward-processing deficits with decreased striatal responses to reward anticipation, though literature is inconsistent. It is unclear whether substance misuse exagg...
Preprint
Full-text available
Objective Attention-deficit hyperactivity disorder (ADHD) is associated with white matter (WM) microstructure. Our objective was to investigate how WM microstructure is longitudinally related to symptom remission in adolescents and young adults with ADHD. Method We obtained diffusion-weighted imaging (DWI) data from 99 participants at two time poi...
Article
Full-text available
Background Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by age-inappropriate levels of inattention and/or hyperactivity-impulsivity (HI). ADHD has been related to differences in white matter (WM) microstructure. However, much remains unclear regarding the nature of these WM differences, and which cl...
Preprint
Full-text available
Background Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by age-inappropriate levels of inattention and/or hyperactivity-impulsivity (HI). ADHD has been related to differences in white matter (WM) microstructure. However, much remains unclear regarding the nature of these WM differences, and which cl...
Preprint
Full-text available
Background: Multiple cognitive theories have been proposed to explain the cognitive impairments observed in Attention-deficit/Hyperactivity Disorder (ADHD). Functional imaging studies building on these theories reveal a heterogeneous pattern of neuronal dysfunction and fail to provide an overarching perspective on the pathophysiology of ADHD. Going...
Preprint
Full-text available
Functional connectivity between brain regions is modulated by cognitive states or experimental conditions. Such connectivity variations can be appreciated in covariance or correlation matrices obtained from fMRI data. A multivariate methodology that can capture fMRI connectivity maps in light of different experimental conditions would be of primary...
Article
Full-text available
When an individual engages in a task, the associated evoked activities build upon already ongoing activity, shaped by an underlying functional connectivity baseline (Fox et al., 2009; Smith et al., 2009; Tavor et al., 2016). Building on the idea that rest represents the brain's full functional repertoire, we here incorporate the idea that task-indu...
Conference Paper
Full-text available
Gene regulatory networks (GRN) are often modeled by Boolean networks to describe their structures and properties. Constraint logic programming (CPL) can be used to infer networks that satisfy constraints applied on their structure and their dynamics. Such approach yield complete satisfiable network sets that can be large. Having such complete sets...
Article
Full-text available
It is being hypothesised that the developing adolescent brain is increasingly enlisting long-range connectivity, allowing improved communication between spatially distant brain regions. The developmental trajectories of such maturational changes remain elusive. Here, we aim to study how the brain engages in multiple tasks (working memory, reward pr...
Poster
Full-text available
Gene regulatory networks (GRN) are often modeled by Boolean networks to describe their structures and properties. Constraint logic programming (CPL) can be used to infer networks that satisfy constraints applied on their structure and their dynamics. Such approach yield complete satisfiable network sets that can be large. Having such complete sets...
Preprint
Full-text available
When an individual engages in a task, the associated evoked activities build upon already ongoing activity, itself shaped by an underlying functional connectivity baseline (Fox et al., 2009; Smith et al., 2009; Tavor et al., 2016). To facilitate understanding the building blocks of cognition we incorporate the idea that task-induced functional conn...
Poster
Full-text available
We introduce an approach to index task- induced changes in fMRI connectivity that: 1) gives full multivariate characterisation 2) provides optimal discriminative linear filters in terms of variance.
Article
Callous-unemotional (CU) traits, i.e., unconcernedness and lack of prosocial feelings, may manifest in Conduct Disorder (CD), but also in Oppositional Defiant Disorder (ODD) and Attention Deficit Hyperactivity Disorder (ADHD). These disorders have been associated with aberrant reward processing, while the influence of CU traits is unclear. Using fu...

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Projects

Project (1)
Project
developing, validating and applying a new method to look at task-specific functional connectivity in fMRI