Rosario Vargas Solis

• Metropolitan Autonomous University

Diuretic and antiurolithiatic activities of hexane, chloroform, methanol and aqueous extracts of Parmentiera aculeata (Kunth) Seem. (Bignoniaceae) were evaluated. The formation of bladder stones was induced surgically placing a magnesium plate in male Wistar rats (250 g). After 28 days the presence of bladder stones was corroborated by radiological...

Diuretic and antiurolithiatic activities of hexane, chloroform, methanol and aqueous extracts of Parmentiera aculeata (Kunth) Seem. (Bignoniaceae) were evaluated. The formation of bladder stones was induced surgically placing a magnesium plate in male Wistar rats (250 g). After 28 days the presence of bladder stones was corroborated by radiological...

Diuretic and antiurolithiatic activities of hexane, chloroform, methanol and aqueous extracts of Parmentiera aculeata (Kunth) Seem. (Bignoniaceae) were evaluated. The formation of bladder stones was induced surgically placing a magnesium plate in male Wistar rats (250 g). After 28 days the presence of bladder stones was corroborated by radiological...

The hexane, methanol and chloroform extracts of bulbs of orchid Prosthechea michuacana (PMIC) were studied for their wound healing and anti-inflammatory properties. Wound healing effects were studied on incision (skin breaking strength), excision (percent wound contraction). Collagen, hexosamine, total protein and DNA content in the granulation tis...

Astianthus viminalis has been used as a medicinal plant for a long time owing to its many physiological actions such as anti-inflammatory and antidiabetic activities. A new tetracyclic triterpenoid 3beta,19alpha-dihydroxyurs-12,20(21)-diene-28-oic acid (1), known constituents oleanolic acid (2) and ursolic acid (3), and the coumarins 7,8-dimethoxyc...

The discovery of novel compounds with pharmaceutical application in cyanobacterias suggests that Blennothrix ganeshii and Microcoleous lacustris Mexican species can be candidates for the bioprocess of target compounds. The antispasmodic effect of hexane, chloroform, methanol and water extracts of B. ganeshii and M. lacustris were studied in vitro i...

Methanol, hexane and chloroform extracts of Prostecheamichuacana (EMM) were studied against carbon tetrachloride (CCl4) induced hepatic injury in albino rats. Pre-treatment with methanolic extract reduced biochemical markers of hepatic injury like serum Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels demonstrated dose dep...

The discovery of novel compounds with pharmaceutical application in cyanobacterias suggests that Blennothrix ganeshii and Microcoleous lacustris Mexican species can be candidates for the bioprocess of target compounds. The antispasmodic effect of hexane, chloroform, methanol and water extracts of B. ganeshii and M. lacustris were studied in vitro i...

The antilithiatic and diuretic activity of 7-hydroxy-2′,4′,5′-trimethoxyisoflavone and 7-hydroxy-4′-methoxyisoflavone, isolated in aqueous extracts of the heartwood of Eysenhardtia polystachya, was tested in rats by observing calculus formation (experimentally induced by implantation of a zinc disc in the urinary bladder) and urine production. A si...

The pentacyclic triterpenes 3-O-α-l-rhamnopyranosyl-(1 → 4)-β -d-glucopyranosyl-(1 → 3)-[β -d-glucopyranosyl-(1 → 2)]-β -d- fucopyranosyl-23,28-dihydroxy-oleane-11, 13(18)-diene (1) and 3-O-α-l-rhamnopyranosyl-(1 → 4)-β -d-glucopyranosyl-(1 → 3)-[β -d-glucopyranosyl-(1 → 2)]-β -d-fucopyranosyl-16,23,28-trihydroxy-oleane-11,13(18)-diene (2) isolated...

The aqueous extract of the bark of Salix taxifolia was tested for antilithiatic and diuretic activities. Urolithiasis was experimentally induced by implantation of a zinc disc in the urinary bladder of rats. A significant decrease in the weight of the stones was observed after treatment in animals with the aqueous extract. This extract caused an in...

The antispasmodic effects of hexane-, chloroform-, methanol- and water-extracts of the orchid Encyclia michuacana were studied in vitro on guinea pig ileum against three spasmogens: acetylcholine (Ach), histamine and barium chloride. The chloroform extract exerted a significant antispasmodic effect on ileum contractions induced by Ach, histamine an...

Two abietane diterpenes were isolated from cyanobacteria Microcoleous lacustris, 20-nor-3alpha-acetoxyabieta-5,7,9,11,13-pentaene and 20-nor-3alpha-acetoxy-12-hydroxy-abieta-5,7,9,11,13-pentaene. These compounds were assayed against Staphylococcus aureus, Staphylococcus epidermidis, Salmonella typhi, Vibrio cholerae, Bacillus subtilis, Bacillus cer...

Psidium guajava, is an important food crop and medicinal plant in tropical and subtropical countries is widely used like food and in folk medicine around of the world. This aims a comprehensive of the chemical constituents, pharmacological, and clinical uses. Different pharmacological experiments in a number of in vitro and in vivo models have been...

A mixture of anthocyanosides from the leaves of Acalypha langiana consisting of cyanidin-3-glucoside, cyanidin-3-rutinoside, peonidin-3-galactoside, petunidin-3-glucoside, delphinidin-3-glucoside, malvidin-3-glucoside, malvidin-5,5-diglucoside and the anthocyanidin pelargonidin, were characterised by means of HPLC and UV-VIS. Phenolic components we...

Two new pentacyclic triterpene taraxast-20-ene-3α-ol (1) and taraxast-12,20(30)-dien-3α-ol (2) were isolated from chloroform extract of leaves of Hylocereus undatus. These triterpenes showed protective activity against the increase of skin vascular permeability in rabbits. The protective effect, measured as the reduction in leakage of Evans blue, w...

Discovery of novel compounds with pharmaceutical application in algae suggested that Oscillatoria limnetica and Hydrodictyon reticulatum species can be candidates for the bioprocess of target compounds. Antispasmodic effect of hexane, chloroform and methanol extracts from Oscillatoria limnetica and Hydrodictyon reticulatum were studied in vitro on...

Acalypha langinia is a well-known plant in the traditional medicine. Based on its traditional use, this plant was selected for evaluation of its wound healing potential. Topical application twice a day for 7 days of 0.05%, 0.1%, 0.2%, 0.4% and 0.5% sterile solution of aqueous extract from leaves of A. langinia significantly increased the healing pr...

The methanol soluble fraction of the leaves of Buddleia scordioides after column chromatography resulted in the isolation of two known iridoid glucosides, catalpol and methylcatalpol. The structures were elucidated by extensive 1D-2D-NMR spectroscopy. The structure of methylcatalpol was confirmed by single-crystal x-ray diffraction. These compounds...

Antispasmodic activity-guided fractionation together with chemical analysis led to the isolation of one novel delta-lactone named oedogonolide from Oedogonium capillare. Identification was based on spectroscopic methods. The oedogonolide produces a significant antispasmodic effect on the contractions of the rat ileum induced by acetylcholine, hista...

γ-Lactone isolated from methanol extract of the leaves of Eryngium carlinae and their antispasmodic effect on rat ileum

Aqueous extracts of leaves, rind, fruit pulp and flowers of Hylocereus undatus were studied for their wound healing properties. Wound healing effects were studied on incision (skin breaking strength), excision (percent wound contraction) and the nature of wound granulation tissues, which were removed on day 7 and the collagen, hexosamine, total pro...

The antioxidant and antiradical activities of 5,7,3'-trihydroxy-3,6,4'-trimethoxyflavone or centaureidin isolated and characterized from Brickellia veronicaefolia were elucidated by heat-induced oxidation in a beta-carotene and linoleic acid system and by the 1,1-diphenyl-2-picrylhydrazyl decoloration test. The centaureidin (32.1%) exhibited antiox...

The dried powder of Daphnia pulex was consecutively extracted with hexane, chloroform, and methanol and destilled under reduced pressure. Concentrated extracts were transferred to a vacuum desiccator and dried to constant weight. The antioxidative properties of the extracts was performed by the ferric thiocyanate method. The hexane, chloroform and...

A methanol extract of the bark of Bocconia arborea was fractionated on silica gel and the fractions analysed using gas chromatography coupled with mass spectrometry (GC-MS). Several benzophenanthridine alkaloids were identified including dihydrosanguinarine, oxysanguinarine, 11-acetonyldihydrochelerythrine, dihydrochelerythrine, chelerythrine, chel...

Hypoglycaemic activity-guided fractionation together with chemical analysis led to the isolation of 12-ursene and a novel triterpene 23,24 dimethyl-24-ethyl-stigmast-25-ene from the chloroform extract of the dried stem of A. mexicana. Identification was based on spectroscopic methods. The isolated triterpenes were tested for hypoglycaemic activity...

Blood glucose levels of normal and alloxan-treated diabetic mice were determined after i.p. administration of various doses of the hexane, chloroform and methanol extracts of Cirsium pascuarense. From the data obtained, it is concluded that the i.p. administration of 100, 150 and 200 mg/kg of hexane extract of this plant produced a significant hypo...

The aqueous extract of the bark of Raphanus sativus was tested for its antiurolithiatic and diuretic activity. The urolithiasis was experimentally induced by implantation of zinc disc in the urinary bladder of rats. Significant decrease in the weight of stones was observed after treatment in animals which received aqueous extract in comparison with...

The effect of Aloysia triphylla hexane extract on male Wistar rats heart was studied, 6 doses were tested: 0.125, 0.366, 0.862, 1.35, 1.82, 2.286 mg/ml, the hexane extract, the extract with barium chloride, the extract with adrenaline. It was found that the inhibitory effect was greater when adrenaline was used. At dose of 0.125 mg/ml an inhibition...

Antimicrobial activity of hexane, methanol, chloroform and aqueous extracts from Bocconia frutescens were tested against sobre B. pumillus, E. coli, EHEC, L. monocytogenes, P. vulgaris, P. aeruginosa, S. cholerasuis, S. typhimurium, S. lutea, S. aureus, S. epidermis, V. cholerae and C. albicans. For determination of antimicrobial activity the stand...

Aqueous extracts of Loeselia mexicana, Calendula officinalis, Teloxys graveolens, Oenothera roseae and Castilleja tenuiflora were tested on the heart activity of male Wistar rats. It was found that C. officinalis, T. graveolens, L. mexicana and O. roseae inhibited the heart contractile activity rising to 100% inhibition at doses of 0.3, 0.5, 0.7 an...

The antidiarrhoeal activity of the hexane, chloroform, methanol and aqueous extracts of Waltheria americana, Commelina coelestis and Alternathera repens, was tested on mice with diarrhoea induced by castor oil and MgSO4. The methanol extract of C. coelestis and A. repens and aqueous extract of A. repens, presented antidiarrhoeal effect, monitored b...

The aqueous extract of the bark of Eysenhardtia polystachya was tested for its antilithiatic and diuretic activity. The urolithiasis was induced experimentally by implantation of a zinc disc in to the urinary bladder of rats. A significant decrease in the weight of stones was observed after treatment in animals that received aqueous extract compare...

The hexane and chloroform extract5 of Salix taxifolia have a relaxing effect on uterus and ileum muscles of Wistar rats. The methanol extract did not alter the normal activity of these muscles.

From the methanol extract of the Arocomia mexicana root a new tetrahydropyrane compound was isolated. Its skeletal structure and relative stereochemistry were established by spectral analysis. Substituent effects have been determined with the hope of providing information about steric interactions and conformation of tetrahydropyran derivatives and...

The pharmacological activity of methanol extracts of Eryngium carlinae and Eryngium comosum was tested on Wistar rats ileon. It was found that both extracts have an inhibitory effect on this tissue. The ileon contractil response was inhibited in 99% by E. carlinae methanol extract at a dose of 28 mg/ml. The same effect was observed when 20 mg/ml of...

Commelina coelestis, a plant that grows in cold climates, has been used since precolumbian times in México, to induce childbirth. The stimulating effect of chloroform, hexane, methanol and aqueous extracts on the uterus and ileum of Wistar rats was studied in vitro. The first two extracts had no activity on the smooth muscle, the aqueous extract in...

Analytical data are presented for the polysaccharide and proteinaceous components of the gum from the seed of Leucaena glabrata, and gum exudate from Spondia purpurea. The yield on hydrolysis of the polysaccharide was β-galactose, 25% and 61%, L-arabinose, 60% and 17%, and D-galacturonic acid, 12 and 22%, respectively. The methoxy and nitrogen valu...

A new compound, 3-methylenhydroxy-5-methoxy-2,4-dihydroxy tetrahydrofurane, has been isolated from a methanol extract of Selaginella lepidophyla. The structure is based on 1H-NMR, 13C-NMR and MS analysis. The compound was tested on uterus (oestrus), ileum and duodenum of Wistar rats. It proved to have a slight inhibitory effect on the contraction r...

Discovery of novel compounds with pharmaceutical application in algae suggested that Oscillatoria limnetica and Hydrodictyon reticulatum species can be candidates for the bioprocess of target compounds. Antispasmodic effect of hexane, chloroform and methanol extracts from Oscillatoria limnetica and Hydrodictyon reticulatum were studied in vitro on...

Introducción En los estudios realizados en las algas se encontraron compuestos con diferentes efectos farmacológicos, como son: analgésico, antiinflamatorios, relajantes musculares entre otros (1). Actualmente se sabe que más del 15% de las algas ofrecen una novedad curativa en relación del 1% de las especies terrestres. Oedogonium capillare (Linn)...