Rosane Michele Duarte Soares

Federal University of Rio Grande do Sul | UFRGS · Departamento de Química Orgânica (DQO)

Objective: This study aimed to develop polymer-based barrier membranes based on poly(butylene-adipate-co-terephthalate) (PBAT) with the addition of 1,3,5-triacriloilhexahydro-1,3,5-triazine (TAT). Materials and methods: Polymeric solutions were used to produce membranes with 5 wt% and 10 wt% of TAT by solvent casting. Membranes without the addit...

Endophytic fungi (EF) have a notable capacity to produce active molecules of industrial importance, such as hydrolytic enzymes. In this study we investigated the production of lipase by EFs isolated from the Amazonian species Aniba canelilla (Lauraceae), characterized the enzymatic extract obtained from the most promising fungus, and applied the li...

Electrospinning is a versatile technique for producing composite scaffolds with nanostructure properties similar to the natural extracellular matrix. Biomaterials possessing mechanical, structural, and biological properties required for bone tissue engineering are a big challenge. However, the effect of fiber alignment, their mechanical properties,...

This study aimed to produce poly(butylene adipate-co-terephthalate) (PBAT) /niobium containing bioactive glasses (BAGNb) composites scaffolds produced by fusion deposition modeling (FDM) printing and evaluate their physicochemical and biological properties in vitro and in vivo. The composite filaments were produced by melt-extrusion with the additi...

Physicochemical properties of gliadin in different solvents (dimethyl sulfoxide (DMSO), H2O, and aqueous ethanol) and pH (9.8, 6.8, and 1.2) were investigated using dynamic light scattering (DLS), zeta potential (ZP), and attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR). Gliadin-DMSO and gliadin-deionized water (H2O)...

This study aimed to develop bioactive guided bone regeneration (GBR) membranes by manufacturing PBAT/BAGNb composites as casting films. Composites were produced by melt-extrusion, and BAGNb was added at 10 wt%, 20 wt%, and 30 wt% concentration. Pure PBAT membranes were used as a control (0wt%BAGNb). FTIR and thermogravimetric analysis characterized...

The development of biodegradable curative systems containing antibacterial drug are fundamental for the promotion of therapeutic actions, reducing the infections caused by microorganisms and being able to substitute conventional dressings which are not biodegradable polymers in their composition. Meeting those needs, poly (butylene adipate‐co‐terep...

Endocrine disrupting compounds (EDC) have the potential to seriously impact ecosystems and humans. To date, numerous techniques have been investigated for removing such contaminants from water, including biodegradation, photocatalysis, ozonation, and the Fenton process. However, these methods are expensive from the perspectives of equipment and ope...

Induced pluripotent stem cells (iPSCs) provide a promising means of creating custom‐tailored cell lines for cellular therapies. Their application in regenerative medicine, however, depends on the possibility that the maintenance and differentiation of cells and organs occur under defined conditions. One major component of stem cell culture systems...

Engineered skin coverings have been adopted clinically to support extensive and deep wounds that result in fewer healthy skin remaining and therefore take longer to heal. Nonetheless, these biomaterials demand intensive labor and an expensive final cost. In comparison to conventional bandages, which do not meet all the requirements of wound care, e...

Nowadays, efficient, economical, and environmentally friendly materials for the removal of emerging contaminants from the aquatic environment have been sought. Electrospun nanofibrous membranes contain fibers with diameters of submicron or nanometer scale, making them very promising adsorbent materials for use in several areas. In this context, the...

Over nearly 70 years, polymers have revolutionized the global economy, manufacturing and, mainly, the fields which require biocompatible materials, as food technology and packaging, controlled drug delivery, tissue engineering, regenerative medicine, wound dressing, anti-allergy textiles, and personal care. While new high-performance polymers were...

Porous starch was produced by enzymatic hydrolysis of rice starch at sub-gelatinization temperatures, applying reaction times of 3, 6, and 12 h, respectively. The effects of α-amylase (AM), amyloglucosidase (AMG), and their mixture (AM+AMG) on starch were studied by morphology, hierarchical porosity, granular structure, and thermal and surface stab...

Biodegradable poly(butylene adipate-co-terephthalate) (PBAT) films incorporated with different levels of the antimicrobial peptide nisin were developed using the electrospinning technique. The characterization included thermal, structural, morphological, mechanical and antimicrobial properties. Thermal analysis indicated good thermal stability of P...

Amylose (AM) tends to form single helical inclusion complexes with suitable agents. These complexes are considered promising biomaterial carrier since the guest molecules can be released later, leading to many applications, especially in the pharmaceutical industry. Rifampicin (RIF) has long been recognized as an active drug against Mycobacterium t...

In the past few decades, pharmaceutical industry has explored protein-based nanoparticles as carriers in drug delivery and controlled release applications. Proteins have been used in drug release systems due to their exceptional characteristics, such as biodegradability, renewable sources, and binding capacity to several drugs. In recent years, gli...

Three-dimensional (3D) printing is becoming an increasingly common technique to fabricate scaffolds and devices for tissue engineering applications. This is due to the potential of 3D printing to provide patient-specific designs, high structural complexity, rapid on-demand fabrication at a low-cost. One of the major bottlenecks that limits the wide...

Biodegradable poly(butylene adipate-co-terephthalate) (PBAT) films incorporated with different levels of the antimicrobial peptide nisin were developed by melt processing. Structural, morphological, thermal, mechanical, and antimicrobial properties of the films were determined. The X-ray diffraction patterns exhibited decreasing levels of intensity...

Natural and biodegradable polymers can be explored as potential biomaterials due to its interesting physical and chemical properties. However, their use in biomaterials applications are limited by their high affinity to water which results in textural transformations that have a strong impact on their mechanical properties and solubility. The curre...

1-D nanostructures are promising materials for development of electrochemical devices offering benefits such as fast electron transfer rates and large surface areas. Copper oxide nanofibers (CuO-NFs) synthesized by electrospinning technique and subsequent thermal treatment, were used to modify paraffin-impregnated graphite electrode (PIGE) for a se...

Amylose is a linear polymer composed almost entirely of α-1,4-linked units. This biopolymer tends to form single helical inclusion complexes with suitable agents. The study of these complexes presents a great interest since the guest molecules that have been trapped at some stage can be release later, thus leading to many applications, especially i...

The greatest challenge for biotechnological processes is to have immobilized enzymes acting as good green catalysts with high reusability rates. In this work, we have produced electrospun fibers from poly (lactic acid)/chitosan blends. Further, we evaluated the influence of these materials as support for lipase immobilization. The PLA/chitosan fibe...

Human embryonic stem cells (ESC) lines to be used for cell therapies must be created and maintained under strict conditions, excluding the use of undefined supplements. Two key steps in the creation of a new embryonic stem cell line are adherence to the substrate and derivation towards the formation of a primary colony. The bovine parthenote embryo...

The incorporation of different concentrations of polymeric nanocapsule suspensions into chitosan hydrogels is proposed, in order to study the structure of a formulation with the properties of great tissue adhesion and controlled release of the nanoencapsulated drugs, represented here by capsaicinoids. The gels presented acceptable acid pH values an...

In this work, nanocomposites of polypropylene (PP) and organically modified montmorillonite (MMT) were evaluated concerning optical, mechanical, and barrier properties. The nanocomposites were prepared by melt compounding using a twin-screw extruder. The PP/MMT films were evaluated by measurements of oxygen and water vapor permeability, and to veri...

The widespread use of polymers from renewable sources is currently unachievable, not only by economic constraints but by the limiting properties of this type of material. Several strategies have been developed to overcome this problem; one of the most extensively explored is the use of nanofillers to improve the biopolymer’s properties such as stif...

During the last few decades, science community has been focused on chemical and physical properties of wheat gluten proteins. These proteins play a key role in determining viscoelastic properties (elasticity and extensibility) of baking quality by conferring also the development of nonfood applications such as polymer blends, adhesives and many oth...

A comparison of cross-linked and native gliadin suspensions, with respect to the state of protein globular structure was carried out using small-angle X-ray scattering (SAXS), dynamic light scattering (DLS) and rheological analysis. Gliadin suspensions were also analyzed in the presence and absence of glycerol. DLS analysis showed that R(h) increas...

The aim of this study was to use nanocomposites of polypropylene (PP) and montmorillonite (MMT), prepared by melt intercalation in a twin-screw extruder, as a food packaging material. The nanocomposites were evaluated by thermal, mechanical, and morphological analyses. Measurements of oxygen and water vapor permeability were also conducted to the n...

The aim of this work has been to elaborate well defined gliadin nanofibers with incorporation of inorganic molecules, such as polyhedral oligomeric silsesquioxane (POSS). Nanofibers were obtained by electrospinning processing, controlling the relevant parameters such as tip-to-collector distance, voltage and feed rate. The fiber mats were character...

In this study gliadin solutions previously cross-linked by 1-(3-dimethylaminopropyl)-3-1-ethylcarbodiimide hydrochloride/n-hydroxysuccinimide (EDC/NHS) and l-cysteine were prepared with different plasticizer concentrations. The obtained films were investigated through mechanical behavior (Young's modulus and elongation at break), thermal characteri...

In this study gliadin solutions were crosslinked with 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) and cysteine. The filmogenic solutions were studied through rheological, sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and FTIR analysis. Gliadin modified by EDC/NHS showed lower vis...

Thermal and rheological properties of starch isolated from two Brazilian barley experimental lines, malting and hull-less, are reported. Gelatinization's thermal properties were To 53.3 and 58C, Tp 59.4 and 62.7C, and ΔH 6 and 6.8 J/g for the malting and hull-less starch, respectively. A trend to slightly higher retrogradation rates were obtained f...

Barley represents an important source of total dietary fiber (TDF) and β-glucans. The chemical composition and partial characterization of two Brazilian barley experimental lines, hull-less and malting, are reported. The range in diameter of the A- and B-type granules was similar in both barley lines, 15 to 28 µm and 8 to 10 µm, respectively. Highe...

Films based on xanthan/wheat starch and xanthan/maize starch were prepared in different proportions and analysed in terms of thermal stability in relation to the degradation reaction in an inert atmosphere. The main gaseous decomposition products were identified by infrared spectroscopy. Xanthan was found to be less thermally stable than starch fro...

In this paper, films were prepared from soy protein and corn starch in different proportions and thermal stability and kinetic parameters were determined through degradation reactions in an inert atmosphere. Solid residues and decomposition products were identified by infrared spectroscopy. Films from corn starch were less thermally stable than soy...

In this study gliadin solutions previously crosslinked by 1-(3-dimethylaminopropyl)-3-1-ethylcarbodiimide hydrochloride/N-hydroxysuccinimide (EDC/NHS) and L-cysteine were casted and the film properties studied through mechanical behaviour (Young's Modulus and Elongation at Break), thermal (DSC, TGA), swelling and water solubility, FTIR measurements...