Rosalba León-Díaz

Rosalba León-Díaz
Universidad Veracruzana | UV · Instituto de Investigaciones Biológicas

Biology PhD

About

15
Publications
2,084
Reads
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300
Citations
Additional affiliations
March 2011 - January 2013
Instituto de Ciencia y Tecnología del Distrito Federal
Position
  • Líder Coordinador de Proyectos de Salud
February 2002 - June 2010
Mexican Institute of Social Security
Position
  • Posgraduated student

Publications

Publications (15)
Article
Objective: Emotional suppression, anxiety, and stress have been described as important psychological features in breast cancer (BC) patients, even before diagnosis. However, the kind of emotional response in these patients, and its relationship to other emotions reported in them is unknown. Here, we analyzed emotional suppression, stress symptoms,...
Article
Full-text available
Introduction: risky eating behaviors have been reported in emerging adults (such as incoming students). Also, body dissatisfaction and nutritional status have been documented as a risk factor in the development of risky eating behaviors. Therefore, the aim of this study is to present the correlations among the presence of risky eating behaviors, bo...
Article
Cleoserrata serrata is used in Mexican-south traditional medicine to treat chicleros ulcer. The phytochemical profile and the anti-inflammatory effect from four extracts obtained by maceration proccess and of the primary fractions from two extracts are described. In addition, the antioxidant, leishmanicidal and antimycobaterial activities and LD50...
Article
Introduction and objectives: Breast cancer (BC) is the most common neoplasm in women worldwide. The World Health Organisation estimates that 30% of deaths due to BC are associated with lifestyle factors. In Mexico there is an obesity epidemic, which favours the appearance of hypertension and diabetes mellitus type 2 (DM2). However, there have been...
Chapter
Breast cancer (BRCA) is the most common neoplasia among women around the world. The Official Mexican Standard states that health services must provide opportune information for the prevention of BRCA. However, this information focuses on the reduction of biological, iatrogenic or environmental risk factors and those related to reproductive history,...
Chapter
A normal pregnancy is defined as the physiological state of a woman from fertilization to the birth of one or more living, healthy and full-term infants. Meanwhile, the term high-risk pregnancy refers to anomalous gestational conditions (e.g. eclampsia), which increase the possibility of pathophysiological states in the mother and/or the infant. Th...
Article
Drug-induced liver injury encompasses a spectrum of diseases ranging from mild biochemical abnormalities to acute liver failure; example of this scenery is hepatotoxicity caused by the first-line antituberculous drugs isoniazid, rifampin and pyrazinamide, which are basic for treatment of drugsensible and drug-resistant tuberculosis. In the search f...
Article
Drug-induced liver injury encompasses a spectrum of diseases ranging from mild biochemical abnormalities to acute liver failure; example of this scenery is hepatotoxicity caused by the first-line antituberculous drugs isoniazid, rifampin and pyrazinamide, which are basic for treatment of drug-sensible and drug-resistant tuberculosis. In the search...
Article
Full-text available
The Immunoglobulin G (IgG) antibody response to different protein antigens of the mammary ductal carcinoma by adult women affected by Breast Cancer (BC) distinguishes at least 103 proteins that differ in their molecular weights (MW). The IgG producing cell clones (nodes) coexist with each other in each individual organism and share energy resources...
Article
Background and aims: Tuberculosis remains a worldwide health problem and requires long-term treatment with several antibiotics; therefore, compliance problems and the emergence of multidrug resistance (MDR) are involved. (-)-Licarin A (LA) was isolated from diverse plants such as Aristolochia taliscana and possesses antimycobacterial, antiinflamma...
Article
Full-text available
We analyzed the antimycobacterial activity of the hexane extract of rhizomes from Aristolochia elegans. Some compounds of this extract were purified and tested against a group of drug-resistant Mycobacterium tuberculosis strains. We also evaluated their antiprotozoal activities. The hexane extract was active against M. tuberculosis H37Rv at a MIC =...
Article
Full-text available
Central dogma suggests that rifampicin resistance in Mycobacterium tuberculosis develops solely through rpoB gene mutations. To determine whether rifampicin induces efflux pumps activation in rifampicin resistant M. tuberculosis strains thereby defining rifampicin resistance levels and reducing ofloxacin susceptibility. Rifampicin and/or ofloxacin...
Article
Full-text available
Tuberculosis (TB - Mycobacterium tuberculosis) is an ancient infectious disease that has appeared once again as a serious worldwide health problem and now comprises the second leading cause of death resulting from a single infection. The prevalence of multidrug resistance (MDR) TB is increasing and therapeutic options for treatment are not always a...
Article
Full-text available
Hexanic and methanolic extracts from aerial parts of T. vulgaris inhibited the growth of M. tuberculosis H37Rv. Bioassay-guided from the most active extract to led obtained secondary fraction with antimicobacterial activity. From the secondary fractions active compounds were obtained and were identified by spectrometric and spectroscopic data. The...

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Projects (3)
Project
Gestational stress is believed to increase the risk of pregnancy failure and perinatal and adult morbidity and mortality in both the mother and her child or children. However, some contradictions might arise from methodological issues or even from differences in the philosophical grounds that guide the studies on gestational stress. Biased perspectives could lead us to use and/or design inadequate/incomplete panels of biochemical determinations and/or psychological instruments to diagnose it accurately during pregnancy, a psycho-neuro-immune-endocrine state in which allostatic loads may be significant.Thus, there is a need t review these notions and propose a model to evaluate and diagnose stress during pregnancy.