Rosa María López-Pintor

Rosa María López-Pintor
Complutense University of Madrid | UCM · Department of Dental Clinical Specialties

Professor; DDS; PhD

About

81
Publications
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714
Citations
Additional affiliations
September 2010 - present
Complutense University of Madrid
Position
  • Professor (Associate)

Publications

Publications (81)
Article
Objective: The objective of this systematic review was to evaluate which salivary biomarkers are altered in patients with burning mouth syndrome (BMS) compared to a control group (CG). Material and methods: A comprehensive literature search was conducted in four databases. Case-control studies evaluating salivary biomarkers in BMS patients were...
Article
Visual impairment is a highly prevalent condition worldwide. Oral health care in this group of patients is not always adequate. This is due to the low awareness of the importance of oral health in this population group and the fact that these patients prioritize their general health over oral health. Therefore, caries and periodontal disease are fr...
Article
Full-text available
Background: The aim of this study is to analyze if the results of the Oral Health Impact Profile-14 questionnaire (OHIP-14) in patients with primary Sjögren's syndrome (pSS) are correlated with salivary flow and level of xerostomia. Methods: This observational cross-sectional study was conducted in sixty-one patients (60 women, one man, mean age...
Article
Full-text available
Objectives To evaluate the efficacy of a gel-containing propolis extract, nanovitamin C, and nanovitamin E as adjuvants to professional plaque removal on desquamative gingivitis (DG). Materials and methods A randomized clinical trial was conducted on patients suffering DG due to mucocutaneous diseases. Patients received professional supragingival...
Article
Full-text available
PurposeThe aim of this study was to investigate the prognostic significance of preoperative inflammatory markers in peripheral blood of patients with oral squamous cell carcinoma (OSCC), and to establish correlations with the infiltrate of macrophages and lymphocytes in the local immune tumor microenvironment (TME).Materials and Methods Neutrophil-...
Article
Background Implant rehabilitation of posterior mandibular defects is frequently associated to a horizontal bone loss. There exist several regenerative techniques to supply this bone deficiency, one of which is the Periosteal Pocket Flap Technique (PPF) proposed by Steigmann et al. to treat small horizontal bone defects. The present study proposes a...
Article
Objective The aim of this study was to evaluate the risk factors associated with xerostomia and hyposalivation in a group of hypertensive patients. Subjects and Methods A cross-sectional study was conducted. Hypertensive patients belonged to two health-care centers were included. Xerostomia was assessed by asking a question and using the Xerostomi...
Article
Full-text available
Background: To evaluate marginal bone loss (MBL) in immediate implant procedures (IIP) placed in conjunction with platelet concentrates (PCs) compared to IIP without PCs. Methods: A search was performed in four databases. Clinical trials evaluating MBL of IIP placed with and without PCs were included. The random effects model was conducted for m...
Article
Background: Zygomatic implants have been described as a therapeutic alternative for patients with severe maxillary atrophy in order to avoid bone augmentation procedures. Taking that into account, in these treatments, the key factor is the position of the implant, the virtual surgical planning (VSP) is widespread among most clinicians before surge...
Article
Background and Purpose Alveolar bone resorption after dental extraction frequently leads to situations in which long-term function and esthetic success of rehabilitations with dental implants is a challenge. Socket shield has been described as an alternative technique to maintain the alveolar ridge when placing immediate implants. The aim of this r...
Article
Objective: Epithelial-mesenchymal transition (EMT) is considered the initial step in the invasion-metastasis cascade. The aim of this systematic review was to study the signature of genes involved in the EMT process in oral cancer (OC) confirmed by protein expression and its possible relationship with oral squamous cell carcinoma (OSCC) prognostic...
Article
Objective: To determine the efficacy of a gel containing propolis extract, nanovitamin C and nanovitamin E as adjuvant to mechanical debridement in the treatment of peri-implant mucositis (PM). Background: Propolis has anti-inflammatory and antibacterial effect that may improve peri-implant health. Methods: A randomized, double-blind study was...
Article
Purpose: To evaluate short-term clinical and radiographic outcomes of bone regeneration procedures using thin cortical porcine xenogeneic bone plates in combination with autogenous bone chips compared with thin autogenous cortical plates and autogenous bone chips. Materials and methods: A total of 19 patients (12 women and 7 men, mean age 58.24...
Chapter
Fungal infections are the most common oral infections of the oral mucosa. Among them, those produced by the genus Candida stand out for their frequency. Oral candidiasis is usually associated with different risk factors that alter the biofilm, increase the invasion of fungi or decrease the host's ability to defend itself against such infections. In...
Article
Objectives To evaluate whether salivary lactate dehydrogenase (LDH) levels are increased in patients with oral cancer (OC) or oral potentially malignant disorders (OPMD) when compared to a healthy control group (CG). Material and methods We conducted a comprehensive search of specialized databases (PubMed/MEDLINE, The Cochrane Library, Web of Scie...
Article
Full-text available
Background: Candidiasis is the most frequent mycotic infection of the oral cavity. The aim of this study was to investigate the presence of clinical oral candidiasis and Candida albicans yeast in a population diagnosed of primary Sjögren's syndrome (pSS) and to study the possible factors associated with this infection. Material and methods: An o...
Article
Background Primary Sjogren’s syndrome (pSS) is an autoimmune disease that leads to salivary and lacrimal gland dysfunction. The adaptive immune response associated with T helper‐2 lymphocytes appears to be altered in these patients. Therefore, the objective of this study was to determine the salivary levels of IL‐6, 5 and 4 in patients with pSS whe...
Article
Background Photobiomodulation has proven to be effective in different painful conditions. Objectives To assess the effect of photobiomodulation for pain management in burning mouth syndrome (BMS) patients, besides analysing the impact on different aspects of quality of life. Methods A randomized, single blind, clinical trial was performed among 2...
Article
We would like to thank you for your comments on the recent study published. The main objective of this case‐control study was to analyse Burning Mouth Syndrome (BMS) patients’ general health, comparing it with a control group. For this purpose, we studied the diseases, medications, blood test alterations, general health status, xerostomia, sleep qu...
Article
Full-text available
The aims of this systematic review are (1) to compare the prevalence of xerostomia and hyposalivation between patients taking antihypertensive drugs with a control group (CG), (2) to compare salivary flow rate between patients treated with a CG, and (3) to identify which antihypertensives produce xerostomia. This systematic review was carried out a...
Article
Background: The relationship of Burning Mouth Syndrome (BMS) with possible alterations in patients' general health has been subject of study and controversy during the last years. Objective: To analyse the general health status of patients with BMS, comparing it with a control group. Methods: A case-control study was conducted to compare the d...
Article
Objective The aim of this study is to describe the findings of a protocolised odontological evaluation of patients with primary Sjögren’s syndrome (pSS) treated in rheumatology units in the Community of Madrid. Methods Multicentric descriptive study in which pSS patients classified according to the American-European consensus of 2002 criteria were...
Article
Purpose: Previous studies have shown that haemodialysis (HD) patients frequently suffer from xerostomia. This problem is associated with difficulties in oral functions, increased risk of oral diseases and interdialytic weight gain (IDWG). The aims of this preliminary study are to evaluate the efficacy and safety of topical dry mouth products in tre...
Article
Background: Propolis has anti-inflammatory, analgesic and healing properties. The purpose of this study was to determine whether a gel containing 2% of propolis extract, 0.2% of ascorbic acid and 0.2% of tocopherol acetate is effective in preventing surgical complications related to impacted lower third molar extractions. Material and methods: A...
Article
Full-text available
Background: To evaluate the presence of oral lesions in a group of patients with primary Sjögren's syndrome (pSS) and compare these results with a matched control group (CG). Material and methods: An observational cross-sectional study was conducted. 61 pSS patients (60 women, 1 man, mean age 57.64±13.52) diagnosed according to the American Euro...
Article
Aims: To evaluate the efficacy of low-level laser therapy (LLLT) for the therapeutic management of neuropathic orofacial pain. Methods: This systematic review was conducted according to PRISMA guidelines. A comprehensive search of the literature was conducted in the PubMed/MEDLINE, Scopus, and Cochrane Library databases up to March 8, 2018, usin...
Article
Full-text available
Background Tyrosine kinase receptor family is involved in tumor growth, pathological angiogenesis and the progression (metastasis) of cancer. Sunitinib (Sutent®) inhibits members of the tyrosine kinase receptor family affecting the induction of angiogenesis and tumor progression. It is not clear if sunitinib increases the risk of osteonecrosis of t...
Article
Objectives: Sjögren's syndrome is a complex and heterogeneous autoimmune disease characterised by ocular and oral dryness (1), which mainly affects the exocrine glands. The objective of this study was to determine the prevalence of sicca syndrome (SS) in the Peruvian population. The age and gender of patients with SS and their national prevalence...
Article
Objectives The aim of this clinical study was to evaluate long‐term outcomes of implant therapy in a cohort of immunosuppressed renal transplant patients compared with a matched control group. Material and methods Pharmacologically immunosuppressed renal transplant patients received dental implant treatment between 2001 and 2011. Periodontal, clin...
Article
Resumen Objetivo El objetivo de este estudio es describir los hallazgos de una evaluación odontológica protocolizada en pacientes con síndrome de Sjögren primario (SSp) atendidos en las consultas de reumatología de la Comunidad de Madrid. Métodos Estudio descriptivo multicéntrico en el que se incluyeron pacientes con SSp clasificados según criter...
Article
Objectives To assess the effects of Xerostom® toothpaste and mouthwash in Primary Sjögren's syndrome (pSS) patients with xerostomia. Subjects and Methods A double‐blinded, randomized study where patients were assigned at baseline test or control products. Patients used the products 3 times/day/28 days. We used a Visual Analog Scale (VAS) for xeros...
Article
Full-text available
Background: Sjögren's syndrome (SS) is an autoimmune disease related to two common symptoms: dry mouth and eyes. Although, xerostomia and hyposialia have been frequently reported in these patients, not many studies have evaluated other oral manifestations. The aim of this systematic review was to investigate prevalence rates of oral lesions (OL) i...
Article
The aim of this systematic review was to assess the primary and secondary stability of dental implants placed at sites prepared with piezoelectric bone surgery (PBS) and conventional drilling (CD). The PubMed/MEDLINE and Cochrane Library databases were searched without date or language restriction up to June 2017. Controlled clinical trials in whic...
Article
Objectives: The main objective of this prospective study was to evaluate the long-term outcome of implant therapy in liver transplant patients (LTP). The secondary goal was to assess several implant- and patient-dependent variables, such as peri-implantitis (PI), peri-implant mucositis (PIM), bone loss (BL), and immediate postoperative complicatio...
Article
Full-text available
Chronic kidney disease (CKD) is a worldwide public health problem that is growing in prevalence and is associated with severe complications. During the progression of the disease, a majority of CKD patients suffer oral complications. Dental implants are currently the most reliable and successful treatment for missing teeth. However, due to complica...
Article
A 35-year-old woman was referred to the Department of Oral Medicine and Orofacial Surgery after several recurrences of an ossifying fibroma (OF) that affected the free and attached gingiva of the maxillary right central incisor. Surgery was performed with a complete excision of the lesion together with the surrounding healthy tissue up to the bone....
Article
Full-text available
Background. Angelman syndrome (AS) is a genetic disease whose incidence varies from one in 10.000 to one in 40.000 newborns. Clinically, it is characterized by a severe growth delay, speech alterations, ataxia, craniofacial abnormalities and strange behaviors. The aim of this paper is to provide a systematic review of the literature regarding the o...
Article
Full-text available
Background: To determine the prevalence of xerostomia and hyposalivation in Haemodialysis (HD) patients, to clarify risk factors, assess patient's quality of life, and to establish a possible correlation among interdialytic weight gain (IDWG) and xerostomia. Material and methods: This study was performed on a group of 50 HD patients. Data were c...
Poster
Full-text available
El Síndrome de Sjögren’s Primario es una enfermedad crónica autoinmune que afecta a las glándulas exocrinas, caracterizándose por la sequedad oral y ocular. Se trata de una enfermedad pobre en su diagnóstico temprano que afecta a nivel oral y extraglandular, deteriorando la calidad de vida de estos pacientes. Así mismo, las técnicas invasivas usada...
Article
Full-text available
Background We want to assess quality of life in elderly patients in relation to the number of remaining teeth, the number of ingested drugs and xerostomía and to determine the correlation between an increased intake of drugs and a greater feeling of dry mouth and to know the most commonly used measures to control xerostomia. Material and Methods 3...
Poster
Full-text available
Introducción: La Leishmaniasis mucocutánea (LM) es una enfermedad producida por un protozoo del género Leishmania, se transmite a los humanos por la picadura de flebótomos hembra infectados, generando la destrucción parcial o completa de membranas mucosas de la nariz, la boca y la garganta. Un promedio de 90% de los casos de leishmaniasis mucocután...
Article
Full-text available
Background: Dabigatran is a newly commercialized drug that is replacing other anticoagulants in the prevention of venous thromboembolism, stroke and systemic arterial valve embolism. It acts directly on thrombin presenting in a dynamic and predictable way, which does not require monitoring these patients. Therefore, we consider the need to assess...
Article
Full-text available
Chronic hyperglycemia is associated with impaired wound healing and higher susceptibility to infections. It is unclear whether patients with diabetes mellitus (DM) present more oral mucosal disorders compared to control groups. The objectives were to compare (a) the prevalence rates of oral mucosal disorders in the DM and non-DM population and (b)...
Article
Full-text available
The presence of xerostomia and hyposalivation is frequent among diabetes mellitus (DM) patients. It is not clear if the presence of xerostomia and hyposalivation is greater in DM than non-DM patients. The aims of this systematic review are (1) to compare the prevalence rates of xerostomia, (2) to evaluate the salivary flow rate, and (3) to compare...
Data
The complete description of how the search was realized for each database is described hereafter. Duplicates were removed introducing all the references found in each database in Refworks and applying “delete duplicates”.
Presentation
Full-text available
This experimental study tried to analyze the role of resveratrol on aged bone metabolism.
Poster
Full-text available
· Introducción y Objetivo: La diabetes es una enfermedad metabólica con una alta prevalencia actualmente. Tiene una gran repercusión a nivel sistémico y presenta una estrecha relación con la enfermedad periodontal. El objetivo de esta revisión es exponer la relación bidireccional existente entre ambas patologías. · Material y Métodos: Se realizó un...
Article
To present a clinical report of a patient treated with corticosteroids for oral pemphigus vulgaris (PV) lesions. PV is the type of pemphigus that most often affects the oral mucosa and tends not to appear in elderly people. Two biopsies were needed for diagnosis. She was treated with oral prednisone and topically with 0.05% clobetasol propionate. A...
Article
Primary Sjögren's syndrome is a chronic systemic autoimmune disease that causes destruction of lacrimal and salivary glands. The most common and earliest symptoms are oral and ocular dryness. Dry mouth makes talking difficult, tasting and chewing properly, impairing quality of life of these patients. The most common oral signs and symptoms are hypo...
Article
Full-text available
Purpose: The aim of this paper was to review the current literature associating the non-bisphosphonate cancer-treatment drugs Denosumab, Bevacizumab and Sunitinib (used with or without bisphosphonate [BP]) with the presence of osteonecrosis of the jaws (ONJ) in patients. Materials and Methods: A literature review was conducted using the keywords o...
Conference Paper
Objective: The main endpoint observation of this long-term prospective controlled study was to evaluate the implant survival rate from baseline up to a maximum of 145 months in a series of immunosuppressed kidney transplant recipients. Secondary goals were to analyze the influence of immunosuppression on several implant- and patient-dependent param...
Conference Paper
Objective: The aim of this prospective study was to evaluate the long-term survival rate of and the presence of inflammatory changes around the implants in a cohort of liver transplant recipients receiving immunosuppressive drugs. Method: The initial study population included 9 immunosuppresed liver transplant patients who received 37 Nobel Bioca...
Article
One of the complications of radiotherapy and chemotherapy is oral mucositis. Since the low energy laser is one of the most frequently recommended interventions by authors and international societies, the aim of this study is to review the scientific evidence on the use of lasers as a preventive and therapeutic in oral mucositis associated with trea...
Article
Full-text available
Objectives: Oral candidiasis (OC) is a frequent oral lesion in renal transplant patients (RTPs). Despite the increased prevalence of OC in RTPs, no study has examined related risk factors. The aims of this study were to analyze the prevalence of and risk factors for OC in RTPs compared with age- and gender-matched healthy control group (HC) as well...
Conference Paper
Objectives: The aim of this prospective controlled study was to evaluate the number of visits to the office due to patient's complaints, patient's perception about improvement after treatment and overall satisfaction in patients diagnosed with oral lichen planus (OLP), compared with a control group with no mucosal lesions, after implant therapy. Me...
Article
The main aim of this prospective-controlled study was to evaluate the implant survival rate in patients diagnosed with oral lichen planus (OLP). The secondary goals were to analyze the presence of implant- and patient-dependent variables. Two groups, including 18 patients diagnosed with OLP and 18 controls, received 56 and 62 implants during the ye...
Article
The aims of this study were to establish the incidence of lip cancer (LC) in a population of renal transplant patients (RTPs), identifying possible risk factors and predictable variables, and to describe the clinical appearance, treatment, and course of LC in this group. The study included 500 patients (307 men, 193 women; mean age 53.63±13.42 year...
Article
Peripheral giant cell granuloma (PGCG) is a reactive lesion that occurs on the gingiva or alveolar mucosa and contains numerous giant cells. Its recurrence rate is 10%. Only five cases associated with dental implants have been reported. This case report describes three additional cases with clinical courses and outcomes. Three women presented with...
Article
The aim of this study was to analyse the prevalence of oral lesions in a group of renal transplant patients (RTPs) compared with healthy controls (HCs). The study included 500 RTPs (307 men, 193 women, mean age 53.63 years) and 501 HCs (314 men, 187 women, mean age 52.25 years). Demographic and pharmacologic data were recorded for all subjects. For...
Article
Gingival enlargement (GE) is a frequent side effect associated with the administration of cyclosporine (CsA) and the calcium channel blockers (CCB). The aims of this study were to determine and compare GE prevalence and severity in 3 groups of renal transplant recipients who had been medicated with CsA versus CsA in combination with nifedipine vers...
Article
Cytomegalovirus (CMV) infection is frequent in kidney transplant recipients. Although involvement of the gastrointestinal tract with CMV has been described, intra-oral localization is rare. The aim of this study was to analyze the incidence, clinical characteristics, treatment, and outcome of renal transplant recipients with oral lesions due to CMV...