Rosa Giménez-García

Hospital Universitario "Rio Hortega" · Department of Internal Medicine

Valproic acid (VPA) is the most widely prescribed antiepileptic drug worldwide and it is also prescribed in the management of bipolar and schizoaffective disorders, social phobias, and neuropathic pain. Valproate is effective against all seizure types and it can be used by patients who are refractory to other anticonvulsants. It is a gold standard...

Background: Cutaneous odontogenic fistulas or sinus tracts are frequently misdiagnosed and incorrectly treated, leading to unnecessary procedures and patient suffering. An understanding of the draining of cutaneous sinus tracts will lead to more appropriate treatment. Most cases respond to conservative, nonsurgical root canal therapy. Our objectiv...

Eritema multiforme inducido por irbesartan

A scabies outbreak is reported which appeared in the Inpatient Pneumology Department in a 500-bed hospital. The outbreak began after the admission of a 90-year old woman referred from a nursing home. A total of 27 secondary cases occurred among health care personnel (14) and patients (13); other 7 cases of likely scabies occurred among 198 contacts...

Lichen planus (LP) is a skin and mucous disease that is relatively infrequent in children. The most common variant is classical LP but, during childhood, it may appear with specific clinical features, including linear, annular, bullous and hypertrophic variants. Mucosal and nail involvement are not usually associated with cutaneous LP in children....

Linear lichen planopilaris of the face is a rare variant of lichen plano- pilaris. Asymptomatic follicular papules in a linear configuration are the characteristic clinical features. The incidence is still unknown, but there are a few cases reported exclusively in male adults. We present the case of a fourteen-year-old girl with linear lichen plano...

Introduction . Lichen planus (LP) is a self-limited disease that predominates among middle-aged adults. There are several clinical forms, and the mucous membranes are affected in 30 % to 70 % of the cases. LP has been linked to numerous systemic diseases, although its etiology is unknown. Objectives . To study the clinical characteristics of LP, e...

Bowen's disease (BD) is a form of potentially malignant intraepidermic carcinoma that usually appears in adults aged more than 60 years old. Lesions can develop anywhere on the cutaneous or mucosal surface. Diagnosis is often delayed as this entity can be mistaken for other more banal and common dermatological diseases. We describe the case of a 71...

Bowen's disease (BD) is a form of potentially malignant intraepidermic carcinoma that usually appears in adults aged more than 60 years old. Lesions can develop anywhere on the cutaneous or mucosal surface. Diagnosis is often delayed as this entity can be mistaken for other more banal and common dermatological diseases. We describe the case of a 71...

Cutis marmorata telangiectatica congenita (CMTC), also known as congenital generalized phlebectasia, nevus vascularis reticularis or congenital livedo reticularis, is an uncommon sporadic congenital disorder, characterized by a localized, segmental or generalized persistent vascular anomaly of the skin, with blue-violet reticular bands; it can be a...

Introduction. Lichen planus (LP) is a self-limited disease that predominates among middle-aged adults. There are several clinical forms, and the mucous membranes are affected in 30% to 70% of the cases. LP has been linked to numerous systemic diseases, although its etiology is unknown. Objectives. To study the clinical characteristics of LP, evalua...

Cases of red fingers syndrome and nodular vasculitis in patients with hepatitis C have rarely been described. Both red fingers syndrome and nodular vasculitis are characterized by microscopic vasculitis, and it has been hypothesized that hepatitis C plays a role in the pathogenesis of cutaneous disorders such as vasculitis, especially in cryoglobul...

Superficial basal cell carcinoma (BCC) account for 15% of all BCC. Treatment of superficial BCC with surgery, cryosurgery and electrodessication often produce anaesthetic scars. We present a case of a 58 year-old male, with multiple superficial BCC, who was treated with imiquimod 5% cream, in a schedule of one application daily three times per week...

Palmoplantar pustulosis (PPP) is a skin disease characterized by chronically recurring sterile pustules on the palms and the soles. Although the aetiology of PPP is unknown, it is interesting to note the high prevalence of tobacco use in these patients. It would seem that there may be a relationship between PPP, autoimmune diseases and alterations...

The association of lichen planus (LP) with liver diseases is well established. The reported prevalence rates of hepatitis C virus (HCV) antibodies in patients with LP tend to appear quite variable. The aim of this study was to assess the prevalence of HCV antibodies in a group of patients with LP and evaluate the clinical characteristics of the sub...

Superficial basal cell carcinoma (BCC) account for 15% of all BCC. Treatment of superficial BCC with surgery, cryosurgery and electrodessication often produce anaesthetic scars. We presenta a case of a 58 year-old male, with multiple superficial BCC, who was treated with imiquimod 5% cream, in a schedule of one application daily three times per wee...

Background Chronic hepatitis C is associated with a host of extrahepatic manifestations many of which may be seen by dermatologists. The main dermatological disorders in infection by hepatitis C virus include vasculitis (mainly cryoglobulin-associated), porphyria cutanea tarda and lichen planus, but other dermatosis have been reported in relationsh...

Introduction The association of lichen planus (LP) with liver diseases, especially primary biliary cirrhosis and chronic active hepatitis, has been observed. Depending on the various studies the prevalence of liver disease in LP patients oscillates between 0.1 and 35%. Recently a possible aetiological role for hepatotropic viruses has been suggeste...

Correo de los lectores FMC-Formación Médica Continuada en Atención Primaria 283 9 9 3. Hematopoyesis extramedular. 4. Proliferación de células fagocíticas. 5. Congestión pasiva, por disminución del flujo sanguíneo en procesos que cursan con hipertensión portal: cirrosis, síndrome de Budd-Chiari, insuficiencia cardíaca congestiva. En la valoración d...

A scabies outbreak is reported which appeared in the Inpatient Pneumology Department in a 500-bed hospital. The outbreak began after the admission of a 90-year old woman referred from a nursing home. A total of 27 secondary cases occurred among health care personnel (14) and patients (13); other 7 cases of likely scabies occurred among 198 contacts...

During the last decade the incidence of cutaneous malignant melanoma (CMM) has increased in different geographic areas around the world. The aim of this study is to know the incidence and clinical characteristics of CMM in the area of Leon between 1980-1989. One hundred nineteen cases corresponding to the total CMM cases diagnosed over the aforemen...

Pustulotic arthro-osteitis is a rare syndrome manifested by palmo-plantar pustulosis and abnormalities involving the anterior chest wall, the spine, the sacroiliac and peripheral joints. We present the case of a patient with pustulotic arthro-osteitis who developed pyoderma gangrenosum. We believe this association has not been previously described...

Summary Penile melanosis or penile lentiginosis, a benign acquired melanosis of the mucoses, is an uncommon dermatosis that appears as pigmented macular lesions with irregular borders. Histologically, there is only hyperpigmentation of the basal layer, with no melanocyte hyperplasia. It shares many features with other mucosal hyperpigmentations suc...