Roman Nahatskyi

Cracow University of Technology | PK · Institute of Organic Chemistry and Technology

The possibility of the construction of five-membered heterocycles, including single heteroatom or systems with two, three and four heteroatoms were critically reviewed based on the recent reports regarding to the [3+2] cycloaddition reactions. Almost all of analysed reaction are realized with high regio- and stereoselectivity.

[3+2] Cycloaddition reactions with the participation of Z-C-(3-pyridyl)-N-methylnitrone and series of E-2-R-nitroethenes were explored experimentally and theoretically in the framework of Molecular Electron Density Theory. It was found that all considered processes are realised under very mild conditions and under full regio- and stereocontrol. The...

A review of the literature, multiple authors in order to systematize information on the effect of temperature in the range of 25-42 ° C on blood proteins, to conduct further studies of the effect of temperature on the stability of fibrinogen molecules in aqueous solution. Study of works on the determination of conformation and stability of protein...