Roman Kostecki

Roman Kostecki
University of Adelaide · ARC Centre for Nanoscale BioPhotonics (CNBP); Institute for Photonics and Advanced Sensing (IPAS)

Doctor of Philosophy

About

29
Publications
4,500
Reads
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400
Citations
Additional affiliations
July 2010 - December 2014
University of Adelaide
Position
  • Research Assistant
Description
  • IPAS brings together physicists, chemists and biologists to pursue a new transdisciplinary approach to science. We are developing novel photonic, sensing and measurement technologies that will change the way science is done.

Publications

Publications (29)
Preprint
Full-text available
Photosynthesis has been shown to be a highly efficient process for energy transfer in plants and bacteria. It has been proposed that quantum mechanics plays a key role in this energy transfer process. There has been evidence that photosynthetic systems may exhibit quantum coherence. As artificial light-harvesting complexes have been proposed to mim...
Article
Full-text available
Oxidative stress is intimately linked to cellular energy balance and occurs when there is an imbalance between production and accumulation of reactive oxygen species in cells and tissues and the ability of a biological system to keep in a redox steady state. While protein carbonyls are an easily detectable marker of oxygen metabolism and oxidative...
Article
Full-text available
Extracellular Ca²⁺ ([Ca²⁺]ex) is an important regulator of various physiological and pathological functions, including intercellular communication for synchronized cellular activities (e.g., coordinated hormone secretion from endocrine tissues). Yet rarely is it possible to concurrently quantify the dynamic changes of [Ca²⁺]ex and related bioactive...
Article
Full-text available
One of the biggest challenges associated with exposed core glass optical fiber-based sensing is the availability of techniques that can be used to generate reproducible, homogeneous and stable surface coating. We report a one step, solvent free method for surface functionalization of exposed core glass optical fiber that allows achieving binding of...
Conference Paper
We show preliminary results of an optical fiber based reversible in-vivo biosensor for understanding redox balance within living systems. The biosensor measured protein carbonyls (oxygen metabolism marker) in pig-skin, live mouse, and wheat plant.
Article
Full-text available
The probing of physiological processes in living organisms is a grand challenge that requires bespoke analytical tools. Optical fiber probes offer a minimally invasive approach to report physiological signals from specific locations inside the body. This perspective article discusses a wide range of such fiber probes developed at the Australian Res...
Article
Calcium is a ubiquitous intracellular signaling ion that plays a critical role in the modulation of fundamental cellular processes. A detailed study of these processes requires selective and reversible sensing of Ca²⁺ and an ability to quantify and monitor concentration changes in a biological setting. Three new, rationally designed, synthesized an...
Article
Full-text available
Intermodal third-harmonic generation using waveguides is an effective frequency conversion process due to the combination of long interaction lengths and strong modal confinement. Here we introduce the concept of tuning the third harmonic phase-matching condition via the use of dielectric nanofilms located on an open waveguide core. We experimental...
Article
Full-text available
Inter-modal phase-matched third harmonic generation has been demonstrated in an exposed-core microstructured optical fiber. Our fiber, with a partially open core having a diameter of just 1.85 µm, shows efficient multi-peak third-harmonic generation between 500 nm and 530 nm, with a maximum visible-wavelength output of 0.96 μW. Mode images and simu...
Article
Full-text available
Sensing platforms for the rapid and efficient detection of metal ions would have applications in disease diagnosis and study, as well as environmental sensing. Here we report the first microstructured optical fiber-based biosensor for the reversible and nanoliter-scale measurement of metal ions. Specifically, a photoswitchable spiropyran Zn2+ senso...
Conference Paper
Full-text available
Corrosion is a multi-billion dollar problem faced by industry. The ability to monitor the hidden metallic structure of an aircraft for corrosion could result in greater availability of existing aircraft fleets. Silica exposed-core microstructured optical fiber sensors are inherently suited towards this application, as they are extremely lightweight...
Article
Full-text available
In this review, we examine recent developments in the field of chemical and biological sensing utilizing suspended-core, exposed-core, and hollow-core microstructured optical fibers. Depending on the intended application, a host of sensing modalities have been utilized including labelled fluorescence techniques, and label-free methods such as surfa...
Article
Full-text available
We demonstrate a promising fiber architecture for generating strong photon-photon interactions. Exposed-core silica optical fibers possess low-loss guidance between 400 and 1700 nm crucial for quantum-logic applications. The potential of this fiber is demonstrated by exciting a two-photon transition within a rubidium vapor using an exposed-core sil...
Article
Full-text available
Femtosecond laser written Bragg gratings have been written in exposed-core microstructured optical fibers with core diameters ranging from 2.7 µm to 12.5 µm and can be spliced to conventional single mode fiber. Writing a Bragg grating on an open core fiber allows for real-time refractive index based sensing, with a view to multiplexed biosensing. S...
Article
Full-text available
We report on a one step functionalization process for optical fiber sensing applications in which a thin film (∼50 nm) polymer doped with sensor molecules is applied to a silica exposed-core fiber. The method removes the need for surface attachment of functional groups, while integrating the polymer, silica and sensor molecule elements to create a...
Article
The results of functionalizing exposed-core optical fiber with multiligand binding sensor molecules for ion detection is presented. We show that the capacity of the sensor molecules to bind multiple ligands is negated when the sensor molecules are covalently bound, making the method ineffective where multiligand binding fluoroionophores are needed....
Conference Paper
Full-text available
Surface Plasmon Resonance (SPR) scattering offers significant advantages compared to traditional reflectivity measurements, essentially turning a non-radiative process into a radiative one. Recently, we have shown that SPR scattering can be used in an optical fiber, enabling higher signal to noise ratio, reduced dependence on the metallic thickness...
Article
Full-text available
The efficient and accurate fabrication of Microstructured optical fibers (MOFs) requires a practical understanding of the ‘draw process’ beyond what is achievable by trial and error, which requires the ability to predict the experimental drawing parameters needed to produce the desired final geometry. Our results show that the Fitt et al. fluid-mec...
Article
Full-text available
This paper summarises recent work conducted on the development of exposed core microstructured optical fibres for distributed corrosion sensing. Most recently, exposed-core fibres have been fabricated in silica glass, which is known to be reliable under a range of processing and service environments. We characterise the stability of these new silic...
Article
Full-text available
The first nanoliter-scale regenerable ion sensor based on a microstructured optical fibre (MOF) is reported. The air holes of the MOF are functionalized with a monoazacrown bearing spiropyran to give a switchable sensor that detects lithium ions down to 100 nM in nanoliter-scale volumes. Ion binding is turned on and off on upon irradiation with lig...
Article
Full-text available
We report the fabrication of silica microstructured optical fibers with the core exposed along the whole length, and characterize the stability of these new fibers when exposed to some typical sensing and storage environments. We show the fiber loss to be the best achieved to date for exposed-core fibers, while the deterioration in the transmission...
Conference Paper
We have demonstrated the use of suspended core optical fibers as dip sensors for biological applications based on fluorophores operating at UV wavelengths for the first time. In this paper, we have demonstrated the use of suspended-core fibers to measure the fluorescence of 7-Amino-4-methylcoumarin (AMC), which is used as the transduction for the s...
Article
Full-text available
Surface Plasmon Resonance (SPR) is a powerful label free optical biosensing technology that relies on the measurement of the refractive index or change of mass in close vicinity of the sensor surface. Therefore, there is an experimental limitation in the molecular weight of the molecule that can be detected and consequently small molecules are intr...

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