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Publications (148)
Adjuvant radiotherapy for breast cancer may involve some incidental exposure of the ipsilateral internal mammary artery to ionizing radiation. However, the relevant evidence is limited and inconsistent. The dataset presented in this article contains the information used to assess the effects of accidental radiation exposure on the internal mammary...
Background: Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an uncommon peripheral T-cell lymphoma most frequently arising around a textured surface breast implant. It has been shown that capsule infiltration (T2, T3 and T4 of the TNM staging system) was an adverse prognostic factor. In this context, chemotherapy (with or wit...
Face transplantation is a viable reconstructive approach for severe craniofacial defects. Despite the evolution witnessed in the field, ethical aspects, clinical and psychosocial implications, public perception, and economic sustainability remain the subject of debate and unanswered questions. Furthermore, poor data reporting and sharing, the absen...
Background:
Oncologic excision and trauma can be responsible for major defects and lymphedema. Free flaps are commonly used for reconstruction. We aimed to determine if lymphatic flow between flap and recipient site can be restored without lymphatic surgery.
Methods:
15 free flaps were performed in different patients in our center. Infrared-base...
The incidence of necrotising soft-tissue infections has increased during recent decades such that most physicians might see at least one case of these potentially life-threatening infections in their career. Despite advances in care, necrotising soft-tissue infections are still associated with high morbidity and mortality, underlining a need for co...
Uterine transplantation is becoming an increasingly realistic therapeutic for uterine infertility. Surgical training on large animal models such as sheep is a prerequisite for establishing a program in humans. The objective of our study was to analyze the predictive factors for successful vascular anastomoses. We performed 40 autotransplants that i...
Background
The objective of breast reconstruction (BR) is to erase the after-effects of total mastectomy by allowing patients to restore their breast shape. The aim of our study was to investigate the body map integration of different types of BR using functional magnetic resonance (fMRI).Patients and Methods
We prospectively enrolled all women und...
Background: Breast implant-associated anaplastic large-cell lymphoma (BI-ALCL) is a rare form of T-cell lymphoma arising adjacent to a breast implant, recently recognized as a provisional entity in the 2017 revised World Health Organization (WHO) lymphoma classification. The pathogenesis of this entity remains elusive even if gene alterations in ep...
Osteotomies during rhinoplasty are usually based on the surgeon's proprioception to determine the number and the strength of the impacts. The aim of this study is to determine whether a hammer instrumented with a force sensor can be used to classify fractures and to determine the location of the osteotome tip. Two lateral osteotomies were realized...
Background: Osteotomies during rhinoplasty are usually based on surgeon's proprioception to determine the number, energy, and trajectory of impacts. Objective: The first objective was to detect the occurrence of fractures. The second objective was to determine when the thicker frontal bone was encountered by the osteotome. Materials and Methods: An...
Background
Compared to other life-threatening infection survivors, long-term health-related quality of life (QOL) of patients surviving necrotizing soft-tissue infections (NSTI) and its determinants are little known.
In this monocentric prospective cohort including NSTI survivors admitted between 2014 and 2017, QOL was assessed during a phone inter...
Osteotomies are common surgical procedures used for instance in rhinoplasty and usually performed using an osteotome impacted by a mallet. Visual control being difficult, osteotomies are often based on the surgeon proprioception to determine the number and energy of each impact. The aim of this study is to determine whether a hammer instrumented wi...
The dissection of the veins is the trickiest step of Uterine transplantation (UTx). Performing the anastomosis of a single uterine vein could bring a therapeutic benefit and simplification of surgery and serve for managing unilateral venous thromboses. The objectives of this project were to evaluate the expression of early markers of ischemia-reper...
Osteotomies are common surgical procedures used for instance in rhinoplasty and usually performed using an osteotome impacted by a mallet. Visual control being difficult, osteotomies are often based on the surgeon proprioception to determine the number and energy of each impact. The aim of this study is to determine whether a hammer instrumented wi...
The 2007 Banff working classification of skin‐containing Tissue Allograft Pathology addressed only acute T cell‐mediated rejection in skin. We report the longitudinal long‐term histological follow‐up of six face transplant recipients, focusing on chronic and mucosal rejection.
We identified three patterns suggestive of chronic rejection (lichen pla...
Surgical cutting guides are increasingly used for maxillofacial reconstruction. They are usually provided by laboratories. In recent years, surgical teams have published studies on the possibility of manufacturing their own cutting guides thanks to 3D printers. The object of this study is to analyze the impact of the sterilization on the surface of...
Introduction
La gangrène de Fournier est une fasciite nécrosante (FN) péri anale, périnéale et génitale qui résulte d’une infection polymicrobienne. Dans la littérature, une cause urogénitale, digestive ou cutanée est souvent trouvée au diagnostic mais la recherche à moyen terme d’une porte d’entrée n’est pas rapportée.
Matériel et méthodes
Étude...
Résumé
Chaque année, en France, sur les près de 60 000 cas de cancer du sein, 20 000 mastectomies (ablation d’un ou des deux seins) seront réalisées. Seulement 20 à 30 % d’entre elles donneront lieu à une recons-truction chirurgicale du sein par implant mammaire, ou transfert tissulaire (lambeau fascio graisseux ou musculo-cutané). La dernière étap...
Background and objective
Quality of life preservation after anti-cancer therapy is a major challenge for breast cancer survivors. Approximately 42–70% of patients who receive systemic therapy for breast cancer, including endocrine therapy, will develop vulvovaginal atrophy (VVA). For these patients, the commonly proposed gel-based treatments for to...
Immediate vaginal reconstruction is usually offered following pelvic exenteration for recurrent cervical cancer in women previously treated with radiotherapy or with severe radiation-induced fistulae. Introduction of muscle-sparing flaps, such as the pedicled vertical deep inferior epigastric perforator (DIEP) flap, provides viable tissues for vagi...
Performing an osteotomy with a surgical mallet and an osteotome is a delicate intervention mostly based on the surgeon proprioception. It remains difficult to assess the properties of bone tissue being osteotomized. Mispositioning of the osteotome or too strong impacts may lead to bone fractures which may have dramatic consequences. The objective o...
Introduction
Les streptocoques béta-hémolytiques (SBH) représentent 30 à 40 % des bactéries responsables de dermohypodermites bactériennes nécrosantes – fasciites nécrosantes (DHBN-FN). Il s’agit principalement de Streptococcus pyogenes, SBH du groupe A (SGA) mais aussi de Streptococcus agalactiae, SBH du groupe B (SGB) et de Streptococcus dysgalac...
Background: BIA-ALCL is a rare subtype of T cell lymphomas associated with textured breast implants which has recently been recognized. The pathogenesis of this entity remains elusive even if mutations in the JAK/STAT pathway have been identified. Little is known about the causes, prognostic factors of this disease, and treatment outcome.
Methods:...
Background:
Necrotizing skin and soft tissue infections (NSTIs) require both prompt medical and surgical treatment. The coordination of multiple urgent interventions by care bundles has improved outcome in other settings. This study aimed to assess the impact of a multidisciplinary care bundle on management and outcome of patients with NSTIs.
Met...
Background:
Necrotising soft-tissue infections (NSTIs) are life-threatening, requiring broad-spectrum antibiotics. Their etiological diagnosis can be limited by poor performance of cultures and administration of antibiotics before surgery.
Objectives:
We aimed to: (i) compare 16S-targeted metagenomics (TM) and unbiased semi-quantitative pan-micr...
Background:
The incidence of facial skin cancers continues to rise, with major studies on their impacts still lacking in the literature. This study reports on the oncological and aesthetic results following surgical management of an orbito-palpebral skin cancer.
Methods:
This retrospective, monocentric study included patients treated for a non-m...
Background:
The availability of more accurate techniques used for transgender surgery has resulted in an increased number of patients requesting facial feminization surgery (FFS). The aim of this study was to present the FFS pre-operative planning of the authors' male-to-female transsexual patients using photo-editing software, computer-aided desi...
Résumé
Le développement des matrices dermiques acellulaires et des matrices synthétiques a permis de contourner les limites classiques de la loge rétromusculaire sous-fasciale en reconstruction mammaire immédiate par prothèse. Ces matrices permettent de placer en un temps l’implant définitif de taille idéale tout en améliorant les résultats esthéti...
Introduction
Les dermo-hypodermites bactériennes nécrosantes-fasciites nécrosantes (DHBN-FN) sont des infections souvent streptococciques ayant une morbi-mortalité importante. Nous avons pris en charge une patiente présentant une DHBN-FN dont la durée d’hospitalisation (DH) prolongée de 64 jours contrastait avec la DH médiane de 21 jours de notre c...
Introduction
Les dermo-hypodermites bactériennes nécrosantes-fasciites nécrosantes (DHBN-FN) sont des infections rapidement progressives du derme et de l’hypoderme, pouvant atteindre le muscle. Nous rapportons le cas d’une DHBN-FN à streptocoque bêta-hémolytique du groupe B (SGB) sans porte d’entrée cutanée évidente, associée à un portage oropharyn...
Introduction
La neurofibromatose de type 1 (NF1) est une maladie génétique d’expressivité variable. Chez les jeunes adultes atteints de NF1, les hommes ont plus de neurofibromes sous-cutanés (NFSC) que les femmes, suggérant un effet de l’imprégnation androgénique sur ce phénotype. Ce n’est en revanche pas le cas pour les neurofibromes cutanés (NFC)...
Background: BIA-ALCL has recently been recognized as a distinct entity among T cell lymphomas. In the French Lymphopath network which has registered almost 60 000 lymphomas since 2010, 50 cases of BIA-ALCL were identified so far. Little is known about the causes, and prognostic factors of this disease.
Methods: since 2016, a WebEx national multidis...
Background: Recent reports have demonstrated uterus transplantation as a relevant solution to treat absolute uterine infertility. Training on animal models is a prerequisite to set up a uterine transplantation program in humans. Sheep have been used as an optimal model for training and research as they display similar vessels size to human. While t...
Objectif de l’étude
Comparaison de la technique d’irradiation axillo-sus claviculaire classique avec la technique d’irradiation ganglionnaire utilisée dans la phase III Amaros en termes de couverture des volumes cibles ganglionnaires (définis par les niveaux I, II, III et IV selon la nomenclature de l’European Society of Radiation Oncology [ESTRO])...
Although the term augmented reality appears increasingly in published studies, the real-time, image-guided (so-called ‘hands-free’ and ‘heads-up’) surgery techniques are often confused with other virtual imaging procedures. A systematic review of the literature was conducted to classify augmented reality applications in the fields of maxillofacial...
Dermatological emergencies are a rare cause of intensive care unit admission but are associated with a high mortality rate and a high risk of long-term sequelae for survivors. They predominantly consist of necrotizing soft tissue infections (NSTI) and severe cutaneous adverse reactions (SCARs), including toxic epidermal necrolysis (TEN), Stevens-Jo...
Background:
Necrotizing soft tissue infections (NSTIs) are severe and rapidly spreading soft tissue infections of the subcutaneous tissue, fascia, or muscle, which are mostly caused by bacteria. Associated rates of mortality and morbidity are high, with the former estimated at around 23%, and disability, sequelae, and limb loss occurring in 15% of...
Dental implants are widely used in the clinic. However, there remain risks of failure, which depend on the implant stability. The aim of this paper is to compare two methods based on resonance frequency analysis (RFA) and on quantitative ultrasound (QUS) and that aim at assessing implant stability. Eighty-one identical dental implants were inserted...
Objective:
Approximately 50% to 70% of breast cancer survivors are affected by one or more symptoms of vulvovaginal atrophy (VVA). For those who cannot take hormone therapy, autologous platelet-rich plasma combined with hyaluronic acid (A-PRP-HA) may provide a new alternative therapy for the treatment of VVA in postmenopausal women with history of...
Introduction:
The morphological result of nipple-areola complex (NAC) reconstruction may be disappointing for patients who undergo skin-sparing mastectomies and immediate breast reconstruction, followed by secondary reconstruction of the nipple-areola complex.The aim of this study was to analyze patient satisfaction after nipple-sparing mastectomy...
Background and objectives:
Breast-conserving surgery and skin-sparing mastectomy are nowadays widely accepted as the standard of care in selected patients with early breast cancer. After an accurate review of the literature, it appeared that no ordered list of the numerous techniques described for conservative breast surgery has been established s...
Background
The acetabular cup (AC) implant primary stability is an important determinant for the success of cementless hip surgery but it remains difficult to assess the AC implant fixation in the clinic. A method based on the analysis of the impact produced by an instrumented hammer on the ancillary has been developed by our group (Michel et al.,...
Background:
The adjunction of platelet-rich plasma with graft fat has been the subject of a few clinical trials which have demonstrated its value in adipocyte survival. The aim of this study was to assess the different efficacies between activated and non-activated PRP on adipose cells in vitro and for adipose tissue graft survival in vivo.
Metho...
Introduction:
Benefits of 3D printing techniques, biomodeling and surgical guides are well known in surgery, especially when the same surgeon who performed the surgery participated in the virtual surgical planning. Our objective was to evaluate the transfer of know how of a neutral 3D surgical modeling free open-source software protocol to surgeon...
Ce travail porte sur l’étude du comportement biomécanique d’un modèle cadavérique et d’un modèle in vitro de l’arthroplastie totale de hanche. Nous avons cherché à mettre en relief et à étudier des paramètres qui pouvaient nous permettre de disposer d’une méthode d’analyse objective de la stabilité de l’implant acétabulaire. La première partie décr...
Introduction
Les dermo-hypodermites-fasciites nécrosantes (DHBN-FN) sont des infections rares et graves (25–30 % de mortalité). Le délai à la 1re chirurgie est un des facteurs de risque de mortalité. Ce délai dépend des délais au diagnostic, à la décision chirurgicale et à l’accès au bloc opératoire. Ces éléments pourraient, selon notre hypothèse,...
Introduction
La physiopathologie de l’hidradénite suppurée (HS) est mal comprise. Les cellules dendritiques (DC), à l’interface entre l’immunité innée et adaptative, pourraient faire le lien entre l’environnement notamment bactérien de la flore commensale et le recrutement chronique de lymphocytes T. La caractérisation des sous-populations de DC n’...
Introduction
Le succès à long terme des prothèses totales de hanche non cimentées dépend de la stabilité primaire de l’implant acétabulaire (IA). Cette stabilité doit être suffisante pour éviter des micromouvements à l’interface os-implant. Toutefois, les contraintes dans le tissu osseux autour de l’IA doivent être suffisamment faibles afin de dimi...
Background:
Managing cutaneous substance loss after debridement is challenging, especially if it is secondary to necrotizing soft tissue infection, such as necrotizing fasciitis and Fournier gangrene. After skin graft reconstruction, the healing process is longer and may be difficult, depending on the wound site, skin defect size, and patient como...
Background:
Internet use for health information has dramatically increased in the past decade. Mobile medical applications (MMAs) could be a useful tool to improve postoperative patient education and care. The objective of this study is to evaluate the impact of an MMA on patient care in plastic surgery.
Methods:
An MMA was developed to improve...
Although the biomechanical behavior of the acetabular cup (AC) implant is determinant for the surgical success, it remains difficult to be assessed due to the multiscale and anisotropic nature of bone tissue. The aim of the present study was to investigate the influence of the anisotropic properties of peri-implant trabecular bone tissue on the bio...
Objective:
The aim of this study was to describe a technique for midface rejuvenation combining lower blepharoplasty, midcheek lift and autologous fat transfer.
Methods:
All patients who underwent a midface rejuvenation procedure performed by the same surgeon and using a classic subciliary blepharoplasty surgical approach were identified. The te...
Purpose
Hormone (anti-estrogen) therapy (HT) plays a major role in hormone receptor-positive breast cancer management. The latest guidelines propose to extend adjuvant treatment duration from 5 to 10 years. The link between HT and thromboembolic or microvascular complications during breast reconstruction has been investigated. However, while estrog...
The hemispherical acetabular cup (AC) implant is used during total hip replacement surgery and is inserted in the acetabulum using impacts applied with an orthopedic hammer. However, the assessment of the AC implant primary stability remains difficult. The aim of this study was to investigate the feasibility of retrieving the AC implant stability b...
Dental implants are widely used clinically. However, implant failures, which may have dramatic consequences, still occur and remain difficult to anticipate. Accurate measurements of implants biomechanical stability are of interest since they could be used to improve the surgical strategy. The aim of this paper is to determine whether quantitative u...
Background:
Necrotising soft-tissue infections (NSTI) are rare, life-threatening conditions.
Objectives:
We aimed to assess whether admitting hospital characteristics were associated with NSTI mortality.
Methods:
We studied the French nationwide hospital discharge database (retrospective national cohort). All patients admitted in 2007-2012 wit...
Introduction:
Using tailored cutting guides for osteocutaneous free fibula flap in complex mandibular reconstruction after cancer resection surgery constitutes a substantial improvement. Autonomously conceiving and manufacturing the cutting guides within a plastic surgery department with computer-aided design (CAD) and three-dimensional (3D) print...
Technique:
The three-dimensional objects that we used and visualized in augmented reality came from the reconstructions made from the CT-scans of the patients. These objects have been transferred through a dedicated application on stereoscopic smart glasses. The positioning and the stabilization of the virtual layers on the anatomy of the patients...
Introduction:
Use of indocyanine green (ICG) near-infrared fluorescence as a dye to assess tissue vascularization is now well standardized. The aim of this literature review was to review and resume the most recent recommendations for ICG use in its plastic surgery applications.
Methods:
A systematic literature review was performed using Medline...
Background:
To describe a new surgical procedure and its results: the vulvo-vaginal rejuvenation by lipofilling and an injection of combined platelet-rich-plasma (PRP) and hyaluronic acid (HA). Sexual life for women is affected by the effect of aging and by post partum traumatism. There are no standard non-invasive treatments to offer to improve t...
Introduction
Les dermohypodermites bactériennes nécrosantes–fasciites nécrosantes (DHBN-FN) sont des infections cutanées rares et graves avec une morbi-mortalité élevée. L’objectif était d’évaluer l’efficacité et la tolérance des traitements médicaux et chirurgicaux dans les DHBN-FN.
Matériel et méthodes
Un protocole a été préalablement publié (Co...
Background
The primary stability of the acetabular cup (AC) implant is an important determinant for the long term success of cementless hip surgery. However, it remains difficult to assess the AC implant stability due to the complex nature of the bone-implant interface. A compromise should be found when inserting the AC implant in order to obtain a...
The restoration of mandibular bone defects after cancer can be facilitated by computer-assisted preoperative planning. The aim of this study was to assess an in-house manufacturing approach to customized cutting guides for use in the reconstruction of the mandible with osteocutaneous free flaps. A retrospective cohort study was performed, involving...
Background The spasm of the internal mammary artery (IMA) and inferior epigastric pedicle (IEP) is critical in deep inferior epigastric perforator (DIEP) flap breast reconstruction. The aim of this study was to assess the safety and the efficacy of endoluminal vasodilators on the prevention of vasospasm in DIEP flap breast reconstruction.
Methods F...
Press-fit surgical procedures aim at providing primary stability to acetabular cup (AC) implants. Impact analysis constitutes a powerful approach to retrieve the AC implant insertion properties. The aim of this numerical study was to investigate the dynamic interaction occurring between the hammer, the ancillary and bone tissue during the impact an...
Objective:
Necrotizing cellulitis (NC) is a severe infection of the skin and soft tissues, requiring an urgent multidisciplinary approach. We aimed to clarify the surgical management of NC in French plastic surgery departments.
Patients and method:
Thirty-two French plastic surgery departments were invited to complete a survey sent by email. Que...
Maxillofacial reconstruction surgery largely relies on the use of microsurgical free transfer techniques. Head and neck cancer surgery and ballistic injuries may lead to significant losses of multitissular substances. Even when the free transfer is successful and the microvascular critical phase is resolved, some functions or anatomic structures ma...
Aim:
Venous congestion is a common cause of DIEP flap failure. When identified intraoperatively, an additional venous anastomosis can improve the venous outflow and prevent flap failure. The aim of this study was to assess if the retrograde limb of the internal mammary vein (IMV) could be considered a good recipient vessel to be used when persiste...
Hidradenitis suppurativa (HS) is a chronic, inflammatory, debilitating, follicular disease of the skin. Despite a high prevalence in the general population, the physiopathology of HS remains poorly understood. The use of antibiotics and immunosuppressive agents for therapy suggest a deregulated immune response to microflora. Using cellular and gene...
Hyaluronic acid (HA) is the most commonly used filler in aesthetic medicine. However, overcorrections are frequent even with experienced practitioner. Hyaluronidase is an enzyme that hydrolyzes HA. Hyaluronidase has been recently proposed to correct unsatisfactory results of HA injections in aesthetic medicine (overcorrection, asymmetry, Tyndall ef...
Purpose
The treatment of lip carcinomas needs tumor surgical resection with safety margins respect. The aim of this study was to report the oncologic and aesthetic/functional outcomes of a retrospective monocentric case series of 39 patients treated for cutaneous lip cancer.
Methods
This retrospective study assessed 56 patients who were treated for...
Dental implant stability is an important determinant of the surgical success. Quantitative ultrasound (QUS) techniques can be used to assess such properties using the implant acting as a waveguide. However, the interaction between an ultrasonicwave and the implant remains poorly understood. The aim of this study is to investigate the sensitivity of...
Background:
The purpose of this study was to evaluate the incomplete excision rate of nasal basal cell carcinomas (BCC) resected with different margins to demonstrate that 3-mm surgical margins could be used as safety margins to reduce esthetic consequences with a low risk of incomplete excision.
Methods:
All patients with BCC of the nose excise...
Objectives:
The increasing frequency of skin tumors and longer life expectancy of the general population are likely to increase the frequency of dermatological surgery among elderly patients. The purpose of this study is to assess the rate of postoperative complications related to dermatological surgery in elderly patients and highlight the factor...
Obtaining primary stability of acetabular cup (AC) implants is one of the main objectives of press-fit procedures used for cementless hip arthroplasty. The aim of this study is to investigate whether the AC implant primary stability can be evaluated using the signals obtained with an impact hammer.
A hammer equipped with a force sensor was used to...
The common principle of injections in esthetic medicine is to treat and to prevent the signs of aging with minimal doses and with more precision and efficiency. This relies on functional, histological, ultrasound or electromyographic analysis of the soft tissues and of the mechanisms of facial skin aging (fine lines, wrinkles, hollows). These injec...
Background:
Necrotizing soft-tissue infection (NSTI) is uncommon but life-threatening. A recent meta-analysis estimated the overall mortality at 23.5%.
Objective:
We sought to identify risk factors associated with mortality in a cohort of patients with NSTI in a tertiary care center.
Methods:
We identified 512 patients with NSTI between 1996 a...
To assess the incidence and presentation of ipsilateral cancer recurrences (ICR) after deep inferior epigastric perforator (DIEP) flap reconstruction for breast cancer.
Data of 247 consecutive women with DIEP flap reconstruction after breast cancer in our institution between 1997 and 2009 were retrospectively reviewed.
Mean follow-up time was 4.1ye...
Bone quality is an important parameter in spine surgery, but its clinical assessment remains difficult. The aim of the work described here was to demonstrate in vitro the feasibility of employing quantitative ultrasound to retrieve bone mechanical properties using an echographic technique taking advantage of the presence of a metallic pin inserted...
