Rodrigo Pirmez

Rodrigo Pirmez
Santa Casa da Misericórdia do Rio de Janeiro · Department of Dermatology

MD

About

64
Publications
29,878
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576
Citations
Additional affiliations
March 2014 - May 2016
Instituto de Dermatologia Prof. Rubem David Azulay
Instituto de Dermatologia Prof. Rubem David Azulay
Position
  • Dermatologist

Publications

Publications (64)
Article
Full-text available
Alopecia areata (AA) is an autoimmune disease characterized by nonscarring hair loss. As a clinically heterogeneous disease, various classification systems have evolved for defining its severity. In this high-level review of the literature, we discuss the traditional classification systems for AA severity and their strengths and weaknesses. Most re...
Article
Background: Frontal fibrosing alopecia (FFA) is a scarring alopecia that affects the frontotemporal hairline. Clinically, it may develop with cutaneous hypopigmentation of the affected areas, which has been associated with a reduction in the epidermal melanocyte count. In trichoscopy, peripilar white halos can be observed, which have been associat...
Article
Full-text available
Background Cutaneous manifestations of COVID-19 may be useful disease markers and prognostic indicators. Recently, post-infectious telogen effluvium and trichodynia have also been reported. Objective To evaluate the presence of trichodynia and telogen effluvium in patients with COVID-19 and describe their characteristics in relation to other signs...
Article
Background Frontal fibrosing alopecia (FFA) has become one of the most common causes of cicatricial alopecia worldwide, but lacks clear aetiology and robust clinical trial evidence for efficacy and safety of agents currently used for treatment. Objectives To enable data to be collected worldwide on FFA using common criteria and assessment methods....
Article
Importance: A recent expert consensus exercise emphasized the importance of developing a global network of patient registries for alopecia areata to redress the paucity of comparable, real-world data regarding the effectiveness and safety of existing and emerging therapies for alopecia areata. Objective: To generate core domains and domain items...
Article
Full-text available
We appreciate the opportunity to discuss some crucial aspects regarding clinical studies on Frontal Fibrosing Alopecia (FFA). The pathogenesis of FFA is multifactorial, with familial occurrence, some genetic markers, and associated clinical conditions; in the meantime, there is a global effort underway to find possible environmental triggers of dis...
Article
Importance: A recent expert consensus exercise emphasized the importance of developing a global network of patient registries for alopecia areata to redress the paucity of comparable, real-world data regarding the effectiveness and safety of existing and emerging therapies for alopecia areata. Objective: To generate core domains and domain items fo...
Article
Full-text available
Introduction: The eyebrows are an important facial feature that shape one's physical appearance and play a role in non-verbal communication. Partial or complete eyebrow loss is seen in most patients with frontal fibrosing alopecia (FFA). Despite the scarring nature of FFA, eyebrow hair regrowth has been previously reported. Nevertheless, treatment...
Article
Full-text available
Background Isotretinoin is a synthetic retinoid, derived from vitamin A, with multiple mechanisms of action and highly effective in the treatment of acne, despite common adverse events, manageable and dose-dependent. Dose-independent teratogenicity is the most serious. Therefore, off-label prescriptions require strict criteria. Objective To commun...
Article
Full-text available
Background Frontal fibrosing alopecia (FFA) is a chronic cicatricial alopecia with unknown etiology and a worldwide rising incidence. Objective The objective of this study was to evaluate the association of FFA with demographic and exposition factors in a Brazilian multiracial population. Methods A multicenter case-control study was conducted in...
Article
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Dissecting cellulitis is a chronic, progressive, and relapsing inflammatory disease that predominantly affects the vertex and occiput of young Afro-descendent men. It produces papules and pustules that develop into nodules, abscesses, and cicatricial alopecia. This article illustrates the evolutive trichoscopy of dissecting cellulitis, from its ear...
Chapter
Scarring alopecias are a heterogeneous group of disorders characterized by the irreversible destruction of hair follicles. Follicular damage in scarring alopecias may be either primary or secondary. In primary cicatricial alopecia (PCA), the hair follicle itself is the principal target for destruction. Secondary cicatricial alopecias result from ev...
Chapter
The new drugs in the development of AGA include PGF2 analogs, a PGD2 receptor antagonist, Wnt pathway activators, an androgen receptor antagonist, a topical JAK inhibitors, and topical finasteride. While many of these have already shown efficacy compared to placebo, none have shown superiority to topical minoxidil; however, they may still have futu...
Chapter
In many patients presenting with hair loss, diagnosis can be made (or at least suspected) through a detailed history and clinical examination. In doubtful cases, some diagnostic tools such as trichoscopy and trichogram may help to confirm diagnosis and, many times, avoid invasive methods, such as a cutaneous biopsy. When a biopsy is needed, trichos...
Chapter
Hair loss in children causes great emotional impact in both patients and relatives. Particularities of this age group along with the lack of clinical trials make therapy in children many times challenging for physicians. In this chapter, we discuss treatments of common types of hair loss in children such as tinea capitis, alopecia areata, trichotil...
Chapter
Healthy hair is manageable, shiny hair with no frizz and good growth rate. Selecting an appropriate shampoo and conditioner is not always easy, for patients or for dermatologists, because each type of hair requires a specific type of care. In order to provide patients with adequate information, dermatologists should be acquainted with the most comm...
Chapter
Hair dyes and hair relaxers are hair care products commonly used to change hair color and shape, respectively. Very popular among patients, these products may be self-applied as a home care treatment or by a professional hair stylist at the hair salon. These products can cause adverse reactions, particularly after improper use. In this chapter, we...
Chapter
Intralesional steroid (IL-S) injections have been used to treat a variety of dermatological and nondermatological diseases. In the treatment of alopecias, IL-S are an important therapeutic tool for many types of both scarring and nonscarring hair loss. This chapter covers practical topics such as the type and concentration of the steroid to be inje...
Book
Conditions of the hair and scalp can be genetic or the result of infection, hormone imbalance, medication, trauma, or underlying primary disease. Regardless, they often cause significant psychological distress and sometimes physical discomfort, though much can be done to treat these complaints. Hair and Scalp Treatments focuses on therapy of hair a...
Article
Full-text available
Background: The frequency of different types of alopecia is not clearly reported in recent studies. Objective: To analyze the frequency of the types of alopecia in patients consulting at specialist hair clinics (SHC) and to assess for global variations. Methods: Multicenter retrospective study including data from patients evaluated at referral...
Article
Full-text available
Lichen simplex chronicus on the scalp, also known as trichoteiromania, can be difficult to manage, as the therapeutic options are limited to topical or intralesional glucocorticoids. We describe a patient with trichoteiromania, presenting three lichenified pruriginous plaques on different regions of the scalp, associated with fracture and loss of h...
Article
Full-text available
Background: Frontal fibrosing alopecia (FFA) is considered a variant of lichen planopilaris affecting mainly the frontotemporal hairline. Since the first report in 1994, several other clinical features have been associated with the disease, such as facial papules (FP). Even though FP have been linked to facial vellus hair follicle involvement, how...
Article
Although trichoscopy has only recently been introduced in the assessment of hair and scalp disorders, it is already considered an essential diagnostic tool by many experts in the field. This article discusses topics that are often a source of doubt among clinicians, and tips that may help dermatologists better perform trichoscopy. Subjects include...
Article
Full-text available
Keratosis pilaris atrophicans represents a group of rare diseases characterized by keratosis pilaris on the extensor surfaces, inflammation and atrophic scarring. The keratosis pilaris atrophicans spectrum includes ulerythema ophryogenes, atrophoderma vermiculatum and keratosis follicularis spinulosa decalvans. Folliculitis spinulosa decalvans is c...
Article
Full-text available
Intralesional corticosteroid (IL-CS) injections have been used to treat a variety of dermatological and nondermatological diseases. Although an important therapeutic tool in dermatology, a number of local side effects, including skin atrophy, have been reported following IL-CS injections. We recently noticed that a subset of patients with steroid-i...
Article
Erlotinib is a selective epidermal growth factor receptor inhibitor utilized in the treatment of solid tumors. Cutaneous side effects, including changes in hair texture and alopecia, have been described. In this case report, we describe two patients with a new finding of loose anagen hairs and pili torti leading to nonscarring marginal and diffuse...
Article
In this second part of the series on dermatomyositis, the diagnosis and its criteria with review of autoantibodies, capillaroscopy, imaging exams, histopathology, muscle biopsy, electroneuromyography, and muscular enzymes will be assessed. The association with malignancy, since it is described as paraneoplasic, will be discussed. The different ther...
Article
Coexistence of frontal fibrosing alopecia (FFA) and lichen planus pigmentosus (LPPigm), an uncommon macular variant of lichen planus, was first reported by Dlova in 2013 in South African patients.(1) In this paper, we report 37 patients with such an association, describe clinical and dermoscopic features of facial LPPigm, and further compare our fi...
Article
Full-text available
Pressure-induced alopecia is an unusual cause of hair loss, and reports of its trichoscopic features are scarce. In this paper, we describe a case of pressure-induced alopecia in which trichoscopic and histopathological findings overlap with those described for alopecia areata.
Article
Dermatomyositis is an inflammatory autoimmune disorder that affects the skin, muscles, and blood vessels. The prevailing clinical manifestations are intense erythema, typically around the eyes and dorsum of the hands, accompanied by proximal muscle weakness. There is one clinical form, called amyopathic dermatomyositis, which lacks muscular symptom...
Article
Full-text available
Hypertrichosis is a common side effect of topical minoxidil and has been reported to occur mainly close to the areas of application. In this paper, we present a case of a 26-year-old woman who developed generalized hypertrichosis 8 weeks after treatment with 5% topical minoxidil solution for alopecia areata. Generalized hypertrichosis is a rare sid...
Article
The combination of methylchloroisothiazolinone(MCI) and methylisothiazolinone(MI), commonly known as Kathon CGTM, is widely used as a preservative in cosmetics, household, and industrial products.1,2 It was first introduced in Europe in the mid-1970s and in 1980 in the United States. Since then, an increasing trend of sensitization to MCI/MI and to...
Article
Full-text available
Traction alopecia (TA) results from prolonged or repetitive tension on the hair and most commonly involves the frontotemporal region. Even though it occurs in patients of different ethnic backgrounds, it is usually observed in African and African-descendant women due to traumatic hair care practices.1 The “fringe sign”, the presence of retained hai...
Article
Full-text available
The authors report a case of sensorimotor polyneuropathy, diffuse cutaneous hyperpigmentation, skin sclerodermiform thickening and papular lesions in the infraclavicular and abdominal region. Besides weight loss, there were diabetes mellitus and hypothyroidism. The alterations were consistent with POEMS (Polyneuropathy, Organomegaly, Endocrinopathy...
Article
We discuss three controversial situations related to disorders of hair growth and the pilosebaceous unit: alopecia areata incognita, pseudopelade of Brocq, and the association of psoriasis and alopecia.
Article
Full-text available
Follicular red dots have been described as a trichoscopic feature of active discoid lupus erythematosus of the scalp and its presence associated with a better prognosis. We report five patients with pigmentary disorders in whom follicular red dots were detected during scalp examination. We suggest that this pattern is probably related to the rich v...
Article
Full-text available
THE AUTHORS PRESENT TWO CASES OF SYPHILIS: one mimicking reactive arthritis and the other Mucha-Habermann disease. Both reports illustrate syphilis as 'the great imitator', a description given by Sir William Osler, and call attention to the strong need for awareness among physicians of all specialties, especially the younger ones, who are not used...
Article
Background: Chemotherapy-induced alopecia (CIA) represents one of the major unresolved problems in clinical oncology. Dermoscopy is a non-invasive technique that has been recently used to facilitate the diagnosis and management of hair and scalp disorders. In the last few years, many studies have been published in this field. However, to our knowle...
Article
Full-text available
We report the dermoscopic features of pemphigus vulgaris (PV) involving the scalp of a 57-year-old African-American female. Among our findings, there were hair casts - movable tubular structures that envelop the hair shafts. We suggest that the development of those casts occurs through acantholysis within the outer root sheath, a mechanism not yet...
Article
Moebius syndrome is a rare disease characterized by congenital facial paralysis and abducens palsy. Involvement of other cranial nerves, orofacial dysmorphism, and limb abnormalities are frequently associated. Reported here is the case of a 10-month-old child born with Moebius syndrome and presenting with holoprosencephaly, following exposure in ut...