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Publications (3)
Formalin-Fixed Paraffin-Embedded (FFPE) tissues are routinely collected, archived, and used for clinical diagnosis, including maternal and neonatal health. Applying FFPE samples to microbiota research would be beneficial to reduce preparation, storage and costs associated with limited available frozen samples. This research aims to understand if FF...
Introduction: It is widely debated whether fetal membranes possess a genuine microbiome, and if bacterial presence and load is linked to inflammation. Chorioamnionitis is an inflammation of the fetal membranes. This research focussed on inflammatory diagnosed histological chorioamnionitis (HCA) and aimed to determine whether the bacterial load in f...
Background: The current gold standard for diagnosing infection/inflammation-related preterm birth is histological chorioamnionitis. Many organisms thought to be associated with preterm birth are difficult to culture by traditional methods. Whilst gene expression studies have inferred a heterogenous picture, metagenomic sequencing allows culture ind...
