Roberto Pozzi Mucelli

Roberto Pozzi Mucelli
University of Verona | UNIVR · Section of Radiology

MD

About

591
Publications
52,858
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10,356
Citations
Additional affiliations
January 2009 - December 2011
Società Italiana di Radiologia Medica
January 2005 - December 2013
Università degli studi di Verona

Publications

Publications (591)
Article
Full-text available
To evaluate if diffusion tensor imaging (DTI) is able to detect morphological changes of peri-prostatic neurovascular fibers (PNF) before and after robot-assisted radical prostatectomy (RARP) and if these changes are related to urinary incontinence (UI) and erectile dysfunction (ED). From October 2014 and August 2017, 26 patients with biopsy-proven...
Article
Purpose To evaluate the role of DTI (with fibretracking) and T2-weighted imaging (T2-WI) used together for predicting extra-capsular extension in patients with localized prostate cancer. Method and materials Thirty-six patients with biopsy-proven diagnosis of prostatic neoplasia performed MRI and underwent radical prostatectomy. Histopathological...
Article
Aim: To correlate the appearance of the retroportal fat plane at preoperative computed tomography (CT) and the pathology findings in resected adenocarcinoma of the pancreatic head (PDAC). Material and methods: Forty-eight patients with resected PDAC of the pancreatic head were included (24 men, 24 women, mean age 63 years, median BMI 24.1). All...
Article
Objectives: Chronic asymptomatic pancreatic hyperenzymemia (CAPH) was described as a benign disease. However, we already described clinically relevant findings requiring surgery or follow-up in half of the subjects. The aim of this study was to evaluate the long-term outcome of CAPH in terms of symptoms and evolution toward chronic pancreatitis....
Article
Background: Pancreatico-enteric anastomosis after pancreaticoduodenectomy can be performed using either a pancreaticojejunostomy (PJ) or pancreaticogastrostomy (PG). Differences in surgical outcomes are still a matter of debate, and less is known about long-term functional outcomes. Methods: Twelve years after the conclusion of a comparative stu...
Chapter
Acute pancreatitis is an acute inflammatory process of the pancreatic gland that can involve pancreatic parenchyma or distant organs. The incorporation of the revised Atlanta classification system into everyday practice would provide the use of a standardized terminology and the chance to correctly classify and recognize every imaging finding of ac...
Article
Full-text available
We compared the effects of 8 weeks of high intensity, aerobic interval training (HIT) and isoinertial resistance training (IRT) on: (i) ˙ VO 2 kinetics during heavy (HiEx) intensity exercise and; (ii) work economy during moderate (ModEx) intensity exercise in 12 healthy elderly men (69.3 ± 4.2 years). Breath-by-breath ˙ VO 2 and muscle deoxygenatio...
Article
Objectives: This study aimed to evaluate magnetic resonance imaging findings of autoimmune pancreatitis (AIP) and to find radiological patterns that could differentiate type 1 and type 2 AIP. Methods: Eight-four patients with diagnosis of AIP were enrolled. Image analysis included pancreatic signal intensity abnormalities, enhancement pattern, e...
Article
Full-text available
Purpose: To assess the accuracy of unenhanced magnetic resonance imaging (MRI) immediately after the percutaneous ultrasound-guided radiofrequency ablation (RFA) of liver malignancy in predicting treatment efficacy at CT follow-up. Materials and methods: Percutaneous ablation was prospectively performed in 23 liver malignancies (20 hepatocarcino...
Article
Objectives: To assess factors associated with radical resection (R0) of pancreatic ductal adenocarcinoma (PDAC) after induction treatment with FOLFIRINOX. Methods: Patients with either locally advanced (LA) and borderline resectable (BR) PDAC undergoing surgical exploration after FOLFIRINOX were retrospectively enrolled. Two pancreatic radiologi...
Chapter
Mucin-producing tumors of the pancreas represent a group of premalignant or malignant neoplasms forming multilocular cysts and lined by tall, columnar mucinous epithelium. These tumors are broadly divided into mucinous cystic neoplasms (MCN) and intraductal papillary mucinous neoplasms (IPMN) which have different biologic behavior and pathologic fe...
Article
Full-text available
Objectives: (1) To illustrate and describe the main types of pancreatic surgery; (2) to discuss the normal findings after pancreatic surgery; (3) to review the main complications and their radiological findings. Background: Despite the decreased postoperative mortality, morbidity still remains high resulting in longer hospitalisations and greate...
Article
Objective: To evaluate if diffusion tensor imaging (DTI) is able to detect changes of periprostatic neurovascular fibers (PNFs) before and after radical prostatectomy (RP), and if these changes are related to post-surgical urinary incontinence and erectile dysfunction. Methods: 22 patients (mean age 62.6 years) with biopsy-proven prostate cancer...
Article
Background and purpose: Intracerebral hemorrhage represents a potentially severe complication of revascularization of acute ischemic stroke. The aim of our study was to assess the capability of iodine extravasation quantification on dual-energy CT performed immediately after mechanical thrombectomy to predict hemorrhagic complications. Materials...
Article
Full-text available
Purpose: To describe CT characteristics of primary pancreatic lymphoma (PPL), a rare disease with features in common with adenocarcinoma. Materials and methods: Fourteen patients were enrolled. CT: unenhanced scan, contrast-enhanced pancreatic and venous phases. Image analysis: tumour location; peri-pancreatic vessel encasement; necrosis; enlarg...
Chapter
Acute pancreatitis (AP) is an acute inflammatory process of the pancreas that can involve regional tissues or even remote organs. In 80–85% of cases AP is self-limiting with minimal clinical manifestations (Bradley 1993). In some cases, however, it can cause even a multiorgan failure (MOF) (Bollen et al. 2007). In this last subset of patients the m...
Article
Background: Since prognosis and treatment of pancreatic endocrine tumors (pNET) are based on tumor grade, contrast-enhanced multidetector computed tomography (MDCT) features of solid non-functioning pNETs were studied and correlated with pathology tumor grading. Methods: MDCTs of diagnosed pNETs were reviewed retrospectively. Each tumor was anal...
Article
Purpose To evaluate the MRI features of paraduodenal pancreatitis (PDP) and to define useful signs to differentiate PDP from pancreatic ductal adenocarcinoma (PDAC). Material and methods We reviewed the MRI scans of 56 patients, 28 affected by PDP and 28 by PDAC, all pathologically proven. The following parameters were evaluated: signal intensity...
Article
Full-text available
The objective of this study is to compare in vivo, the accuracy of single-energy CT (SECT) and dual-energy CT (DECT) in renal stone characterization. Retrospective study approved by the IRB. 30 patients with symptomatic urolithiasis who underwent CT on a second-generation dual-source scanner with a protocol that included low-dose 120 kV scan follow...
Article
Background: The purpose of the study is to evaluate the utility of acoustic radiation force impulse (ARFI) on pancreatic tissue as a preoperative predictor of postoperative pancreatic fistula (POPF). Studied patients underwent exclusively to pancreaticoduodenectomy (PD) surgery. Methods: Shear wave velocity of pancreas was measured using ARFI in...
Article
Aim: To differentiate uric acid from non-uric acid renal stones based on their spectral attenuation values. Materials and methods: The present study was approved by the institutional review board and the need for informed consent was waived. Thirty-three consecutive patients (21 men, 12 women; mean age 55 years) with symptomatic urolithiasis und...
Article
Objective To evaluate the diagnostic performance of virtual non-contrast (VNC) images in detecting intracranial haemorrhages (ICHs). Methods Sixty-seven consecutive patients with and 67 without ICH who underwent unenhanced brain CT and DECT angiography were included. Two radiologists independently evaluated VNC and true non-contrast (TNC) images fo...
Conference Paper
Full-text available
O1 Tumour heterogeneity: what does it mean? Dow-Mu Koh O2 Skeletal sequelae in adult survivors of childhood cancer Sue Creviston Kaste O3 Locoregional effects of breast cancer treatment Sarah J Vinnicombe O4 Imaging of cancer therapy-induced CNS toxicity Giovanni Morana, Andrea Rossi O5 Screening for lung cancer Christian J. Herold O6Risk stratific...
Article
Purpose: To define imaging criteria of benign and malignant nature in patients with main pancreatic duct (MPD) stenosis. Materials-methods: S-MRCPs of 35 patients with pancreatitis and 14 with adenocarcinoma were evaluated. Results: Adenocarcinoma caused higher prevalence of complete stenosis (14/14-100% vs 17/35-49%), dilated side-branches (1...
Article
Full-text available
The many factors influencing the shear wave velocity (SWV) measured with Acoustic Radiation Force Impulse (ARFI) are examined in order to define the most correct examination technique. In particular, attention is given to the information achieved by experimental models, such as phantoms and animal studies. This review targets the clinical applicati...
Article
Full-text available
La pancreatitis autoinmune (PAI) es una forma distinta de pancreatitis crónica, que se caracteriza por un mecanismo patogénico autoinmune. Su frecuencia es levemente mayor en los pacientes de sexo masculino (60%) y la edad promedio de presentación oscila entre los 40 y 60 años, aunque el rango etario es mucho más amplio (de 14 a 80 años). Desde el...
Chapter
Cystic neoplasms of the pancreas are rare pancreatic tumors; nowadays they are diagnosed more frequently due to the spread of accurate imaging techniques. The WHO classification distinguishes serous cystic neoplasms (SCNs), mucinous cystic neoplasms (MCNs), intraductal papillary mucinous neoplasms (IPMNs), and solid pseudopapillary neoplasms (SPNs)...
Article
Full-text available
Aim: The objective of this study was to evaluate the efficacy of percutaneous radiofrequency ablation of locally advanced pancreatic cancer located in the pancreatic body. Materials and methods: Patients with biopsy-proven locally advanced pancreatic adenocarcinoma were considered for percutaneous radiofrequency ablation. Postprocedural computed...
Article
Cavernoma is a vascular hamartoma, which represents 10–20% of all central nervous system vascular malformations. The majority (80%) of them are supratentorial, while involvement of the cranial nerves and the optic pathways is extremely rare. The main clinical presentation of optochiasmatic cavernomas consists of chiasmatic apoplexy, which is a neur...
Article
Secretin is a hormone that stimulates the exocrine pancreatic secretion of bicarbonate-rich fluid from the acinar cells of the pancreas that accumulates within the pancreatic ductal lumen. The exogenous administration of secretin improves the visualization of pancreatic ducts at magnetic resonance (MR) cholangiopancreatography (MRCP), because of an...
Poster
Objectives. To compare fetal cerebral MRI findings with postnatal MRI results; to evaluate fetal MRI accuracy compared with fetal US in the diagnosis of fetal CNS anomalies. Materials and Methods. This retrospective study included 15 pregnant women with fetal US findings of midline and/or posterior fossa malformations, who underwent fetal MRI exami...
Article
Hereditary hemochromatosis, one of the commonest genetic disorder in Caucasians, is mainly associated to homozygosity for the C282Y mutation in the HFE gene, which is highly prevalent (allele frequency up to near 10% in Northern Europe) and easily detectable through a widely available "first level" molecular test. However, in certain geographical r...
Article
First Episode Psychosis (FEP) patients are of particular interest for neuroimaging investigations because of the absence of confounding effects due to medications and chronicity. Nonetheless, imaging data are prone to heterogeneity because for example of age, gender or parameters settings differences. With this work, we wanted to take into account...
Article
Background: Acoustic Radiation Force Impulse (ARFI) is a new ultrasound technique that evaluates mechanical properties of tissues. To evaluate the use of ARFI with shear waves speed quantification for pancreatic masses characterization during the ultrasound examination. Methods: 123 pancreatic lesions were prospectively evaluated. Median shear w...
Article
Objectives: To determine the accuracy of MR imaging in differentiating mucinous cystoadenomas (MCAs) from mucinous cystoadenocarcinomas (MCACs) of the pancreas, with histopathologic analysis as the reference Standard, for a better surgical planning. Methods: A total of 65 patients with histopathologically provenmucinous cystic neoplasms (MCNs) u...
Chapter
Congenital uterine anomalies (mullerian duct anomalies) comprise a spectrum of developmental malformations associated with varying degrees of adverse reproductive outcomes. Although traditionally diagnosed by hysterosalpingography or ultrasound, further elaboration of the findings frequently was performed with laparoscopy/laparotomy and hysteroscop...
Chapter
Fibroids, the most common benign neoplasms of the uterus, are well-defined masses in the myometrium of the uterus, once surrounded by a pseudocapsule, and composed of smooth muscle with varying amount of fibrous connective tissue. They occur more frequently in the body of the uterus rather than in the cervix or between the folds of the broad ligame...
Chapter
Endometrial carcinoma (EC) represents the most common gynecological malignancy in developed countries and usually manifests with abnormal vaginal bleedings in perimenopausal women. The diagnosis of EC is performed by means of transvaginal sonography and endometrial biopsy, and the treatment of choice is surgery. MRI is the imaging modality of choic...
Chapter
Prostate cancer is the most common cancer and the second most common cause of cancer-related death among men. Because of the advent of prostate-specific antigen (PSA) concentration in serum screening, most prostate cancer new cases are clinically localized at diagnosis, and the 5-year relative survival rate approaches 100 %. Until now, patients wit...
Chapter
In the last years, MRI became the most important imaging technique in the evaluation of the uterine cervix due to its capability to delineate exactly the normal anatomical structures of this uterine component and to detect benign or malignant pathologic changes in its context. This is particularly true for cervical cancer. MR images, in fact, permi...
Article
Objectives: To evaluate the diagnostic accuracy and complication rate of percutaneous ultrasound-guided fine-needle aspiration (US-FNA) of solid pancreatic neoplasms through the analysis of 10-year experiences of two centres. Methods: Clinical, radiological and pathologic data of 2,024 patients with solid pancreatic masses who underwent US-FNAs...
Chapter
Pancreatic metastases are uncommon entities. Primary pancreatic lymphoma is another rare pancreatic neoplasm that accounts for less than 1 % of all pancreatic tumors.
Article
Full-text available
The purpose of this article is to discuss the use of contrast-enhanced ultra-sound (CEUS) in focal liver lesions. Focal liver lesions are usually detected incidentally during abdominal ultrasound. The injection of microbubble ultrasound contrast agents improves the characterization of focal liver lesions that are indeterminate on conventional ultra...
Conference Paper
Purpose: To evaluate MR-cholangiopancreatography (MRCP) findings before and after secretin administration in patients with main pancreatic duct (MPD) stenosis and to define imaging criteria of benignity and malignancy. Material and Methods: Secretin-enhanced MRCPs of 42 patients were evaluated; 35 presented benign conditions and 7 pancreatic canc...
Article
To investigate whether the different location of pancreatic adenocarcinoma affects the lobar distribution of metastases to the liver. From all patients who underwent multidetector computed tomography (MDCT) examinations for staging of pancreatic adenocarcinoma in the last 4 years we selected 80 patients (42 men, 38 women; mean age, 60.56 years) wit...
Article
Full-text available
We investigated the effect of 8 weeks of high intensity interval training (HIT) and isoinertial resistance training (IRT) on cardiovascular fitness, muscle mass-strength and risk factors of metabolic syndrome in 12 healthy older adults (68 yy ± 4). HIT consisted in 7 two-minute repetitions at 80%-90% of V˙O2max, 3 times/w. After 4 months of recove...
Article
Full-text available
The aim of the study was to evaluate the prevalence of collateral findings detected in computed tomography coronary angiography (CTCA) in a multi-center registry. We performed a retrospective review of 4303 patients (2719 males, mean age 60.3 ± 10.2 years) undergoing 64-slice CTCA for suspected or known coronary artery disease (CAD) at various acad...
Conference Paper
Purpose: To evaluate secretin enhanced-MRCP (S-MRCP) features of patients with pancreas divisum and Santorinicele, before and after Minor Papilla Sphincterotomy. Methods and Materials: S-MRCP examinations of 519 patients with suspected pancreatic disease were included. Size of the main pancreatic duct, presence and caliber of Santorinicele were eva...
Article
Contrast-enhanced ultrasonography (CEUS) improves the characterization of pancreatic masses. CEUS is in fact a safe and accurate imaging method to evaluate the vascularity of pancreatic lesions. CEUS should be performed when possible immediately after the ultrasound (US) detection of a pancreatic mass. CEUS is accurate in the characterization of du...
Article
Contrast-enhanced ultrasound (CEUS) allows a better characterization of pancreatic masses than non-enhanced ultrasound. It utilizes a microbubbles contrast agent, leading to a visualization of macro- and micro-vasculature of benign or malignant tissues. At CEUS, pancreatic ductal adenocarcinoma usually presents as an ill-defined mass, showing poor...
Article
To evaluate secretin-enhanced MRCP (S-MRCP) findings of patients with pancreas divisum and Santorinicele, before and after minor papilla sphincterotomy. S-MRCP examinations of 519 patients with suspected pancreatic disease were included. Size of the main pancreatic duct, presence and calibre of Santorinicele were evaluated. Duodenal filling was ass...
Article
Purpose To determine the accuracy of ENZIAN score, as detected on MR imaging, compared to surgical-pathologic findings. Materials and methods This retrospective study was approved by the investigational review board and the requirement for informed patient consent was waived. 115 patients were included according to following criteria: tubo-ovarian...
Chapter
Endometriosis, defined as the presence of endometrial glands and stroma outside the endometrium, is a common gynecological disorder affecting women in reproductive age, associated with chronic pelvic pain and infertility. Its pathogenesis is complex and still unclear, probably multifactorial. The ovaries are the most common sites affected, but endo...
Chapter
Pancreatic neuroendocrine tumors (P-NETs), also known as islet cell tumors, are the second most common pancreatic solid lesions. They are epithelial tumors with neuroendocrine differentiation, and they are clinically defined as functioning (syndromic) or nonfunctioning (nonsyndromic), depending on the presence of a syndrome related to inappropriate...
Chapter
Rare pancreatic neoplasms are a heterogeneous group of neoplasms infrequently seen in any given individual clinical practice.
Chapter
Ductal adenocarcinoma is the most common primary malignancy of the pancreas, accounting for about 80 % of malignant pancreatic tumors. It is a highly aggressive tumor with an overall 5-year survival rate less than 5 %. Prognosis and treatment depend on whether the tumor is resectable or nonresectable, which mostly depends on the time of diagnosis.
Chapter
Serous pancreatic neoplasms are cystic tumors, usually detected as solitary lesions. The most common is the serous cystadenoma (SCA). SCA typically presents as a solitary multilocular microcystic lesion with a honeycomb architecture.
Chapter
The prostate gland is the male organ most commonly afflicted by benign or malignant neoplasms. Benign prostatic hyperplasia (BPH) represents the most common benign tumor in men after the fifth decade, and its incidence is age related. BPH uniformly originates in the transition zone and determines obstructive and irritative symptoms caused by an inc...
Chapter
Fetal MRI is a noninvasive method to study both fetal and maternal structures. MRI intervenes as a third-level exam, after the first- and second-level ultrasound imaging, with various aims: to confirm ultrasound diagnosis, to search for other possible associated anomalies, and to obtain the right information in order to do a prognostic prediction a...
Book
Based on the experience of two Italian referral centers, the book depicts the characteristic findings obtained when using MR imaging to study the male and female pelvis including the obstetric applications. Each chapter provides a comprehensive account of the use of the imaging technique of examination, including the most recent advances in MR imag...
Article
Full-text available
Autoimmune pancreatitis (AIP) is characterized by obstructive jaundice, a dramatic clinical response to steroids and pathologically by a lymphoplasmacytic infiltrate, with or without a pancreatic mass. Type 1 AIP is the pancreatic manifestation of an IgG4-related systemic disease and is characterized by elevated IgG4 serum levels, infiltration of I...
Article
Full-text available
To identify magnetic resonance (MR)/MR cholangiopancreatography (MRCP) imaging signs helpful in the differential diagnosis between serous cystadenomas (SCAs) and mucinous cystic neoplasms (MCNs), arising from the body/tail of the pancreas. This retrospective study had institutional review board approval and informed consent was waived. Fifty-three...
Chapter
Adnexal masses (AMs) are common findings among both premenopausal and postmenopausal women. The main goals of an initial diagnostic work-up for an AM are to rule out malignancy and to differentiate between AM requiring surgical intervention and those that can be managed conservatively. Among the gynecological sources, diagnostic entities can be bro...
Article
Aim: To evaluate the magnetic resonance (MR) imaging-MR cholangiopancreatographic (MRCP) findings of focal forms of autoimmune pancreatitis (AIP) to describe ductal involvement at diagnosis. Methods: MR examinations of 123 patients affected by AIP were analysed. We included 26 patients who satisfied International Consensus Diagnostic Criteria an...
Article
Full-text available
Indication/purpose: To review contrast‐enhanced ultrasound features of the most common pancreatic tumours. Methods: Contrast‐enhanced ultrasound (CEUS) can provide distinctive features of pancreatic tumours that are reported in the present paper, providing radiologic‐pathological correlations and clarifying the main differential diagnosis. Conclusi...
Article
A case of localization in the bowel of congenital fibrosarcoma (a rare soft-tissue tumor usually occurring in the extremities) causing intestinal obstruction in a newborn girl is described. A focal thickening of the ileal wall with features mimicking intussusception was identified at sonography; the final diagnosis was achieved by means of molecula...
Article
Full-text available
Progressive hepatic fibrosis can lead to cirrhosis, so its early detection is fundamental. Staging fibrosis is also critical for prognosis and management. The gold standard for these aims is liver biopsy, but it has several drawbacks, as it is invasive, expensive, has poor acceptance, is prone to inter observer variability and sampling errors, has...
Article
Purpose: To evaluate the magnetic resonance imaging (MRI) findings of solid pseudopapillary neoplasm (SPN) of the pancreas. Methods and materials: From January 2006 to December 2013, 41 patients with SPN of the pancreas were retrospectively evaluated. Inclusion criteria were the execution of an MR examination and tumor resection with an histopat...
Article
Objective: To evaluate the potential usefulness of perfusion computed tomography (CT) for the estimation of hepatic functional reserve in patients scheduled for surgical resection and to compare the results with those of the indocyanine green retention test results. Methods: Thirty-one patients with hepatobiliary malignancies were included. Perf...