Roberto Musci

Istituto Clinico Humanitas IRCCS | Humanitas · Department of Urology

Experimental and preliminary clinical studies have suggested that the pineal hormone melatonin (MLT) may stimulate hormone receptor expression on both normal and cancer cells. Moreover, MLT has appeared to inhibit the growth of some cancer cell lines, including prostate cancer, either by exerting a direct cytostatic action, or by decreasing the end...

We present our experience with three different lithotriptors: Dornier HM3, EDAP LT02 and Piezolith 2300. Materials and methods: 1876 patients with ureteral stones were treated between 1 January 1988 and 1 January 1996. The above 3 lithotriptors were used. In 925 patients the stones were located in the upper ureter, in 182 in the middle ureter and i...

The intravenous immunotherapy with high-dose interleukin-2 (IL-2) would constitute one of the most effective treatments of metastatic renal cell carcinoma (RCC). More recently, IL-2 subcutaneous therapy has also appeared active, either alone or in association with interferon, with results comparable to those found with the intravenous route of inje...

Benign prostatic hypertrophy provokes clinical manifestations correlated on one hand to a static obstructive component, due to the increase in glandular size, and on the other hand to a dynamic component, controlled by the alpha adrenergic autonomic system which gives the smooth muscular tonus of the prostatic adenoma. The alpha adrenergic receptor...

From May 1992 to December 1993 (17 months), 18 patients with AIDS, 15 male and 3 female, age range from 25 to 50, were found to have severe voiding disorders related to neurogenic bladder dysfunction. All patients underwent neurologic, urologic and immunologic evaluation and were staged as AIDS-IVB. The neurological evaluation demonstrated: cryptoc...

The technique for radical cystoprostatectomy was modified to avoid injury to the branches of pelvic plexus that innervate the corpora cavernosa (monolateral neurovascular bundle preservation or "Nerve sparing technique"). The studies of Walsh and coll. demonstrated that the branches of pelvic plexus that innervate the corpora cavernosa are situated...

The preliminary results of an ultrasound study of the anatomy of the female urethra are presented. In this study an intraluminal probe was used and the results were compared with permicturitional transvaginal ultrasound data. Both morphometric and morphological results of the two methods coincided. The images obtained with the intraluminal ultrasou...

The Authors present a new infrared laser device with endourethral atraumatic optic fiber capable of effectively treating patients with newly acute chronic prostatitis. Cost-benefit ratio is excellent and the method is minimally invasive.

Radical pelvic surgery in women is considerably handicapped by serious neurogenic complications, commonly due to lesions in the inferior hypogastric plexus or its branches, which cannot be easily identified in the female pelvic cavity. The pelvic cavities of 42 adult female cadavers were studied and the relations between the nervous structures and...

Endoluminal sonography performed with 12.5 MHz miniature transducer-containing catheters with diameter of 6 or 9 Fr., is a new technique for the study of urinary tract. We studied: U.S. scan of 10 corpes and 10 operatory specimens (bladders and kidneys) with anatomic measurement in vitro. U.S. scan of 20 patients "in vivo" with pathologies involvin...

Infection by the HIV virus affects the urogenital system in a minor percentage of cases in comparison to other organs such as the lungs, the central nervous system and the haemolymphopoietic system. In recent years however, with the continued spread of the disease also urologists find themselves dealing with the various urogenital pathologies that...

With the growing number of patients with Hiv infection there has been a marked increase in the incidence of unusual genitourinary pathologies. Urologists find themselves dealing with opportunistic infection (viral and fungal infection), penile and testicular neoplasm and neurological bladder. The Authors present their experience and describe the pr...

Infection by Hiv virus affects the urogenital system in a minor percentage of cases in comparison to other organs such as the lungs, the central nervous system and the haemolymphopoietic system. In recent years however, with the continued spread of the disease, also urologists find themselves dealing with various urogenital pathologies that are pre...

The echo-doppler is a non-invasive diagnostic method that makes evaluation of the morphology and the renal intraparenchymal vessel flow possible. Due to the development and spread of percutaneous methods and to the large number of patients who undergo extracorporeal lithotripsy, the renal parenchyma suffers traumas of which neither the short no lon...

Treatment of benign prostate pathology often has no effect on the symptomatology of the patient. For this reason we used an infrared laser ray, of which the biophysical effects on tissue are well noted: stimulation of lymphatic drainage, pain reduction, microcirculation, trophism and tissue elasticity increase. The laser was used on the prostate vi...

While the invasion of the bladder by neoplastic cells during acute lymphatic leukaemia in children has been reported by various authors, the leukaemic invasion of the bladder in adults is extremely rare. We report a case of recurrence of A.L.L. in the bladder presenting colicky symptomatology and obstruction of the excretory tracts.

The Authors report their recent experience about a penis trauma with a subtotal organ skinning. After the literature analysis, the AA. explain the case, with a particular attention to the surgical repairing technique. The surgical outcomes are discussed and it is re-marked the necessity of a precise diagnostic approach and follow up, also to preven...

Penile metastases are uncommon lesions: most often secondary to a primary pelvic cancer (prostate, bladder and rectum) they have a unfavourable prognosis. The appearance of disseminations is still controversial and there is not an efficacious therapy. Priapism may be present or not. The Authors report their experience on a penile metastasis seconda...

The Authors discuss a recent case report treated with radial cystectomy associated with a secondary urinary derivation using the caecum-colon reservoir. After having reviewed the various surgical procedures involving the urinary derivations, the Authors describe the technique used by them paying particular attention to the positive aspects of havin...

The experience of our group in Milan covers 1,055 cases treated between the first of February 1985 and the first of September 1987. At the present time, the procedures used to treat staghorn calculi are to reduce the mass of the stone by conventional surgery or by a percutaneous nephrolithotomy and then to treat with shock waves. This means, howeve...

The results of treating kidney/ureteral lithiasis with piezoelectric lithotripters are reported. This paper contains the medium-term results of the treatment of 177 patients treated with piezoelectric lithotripsy using the EDAP LT01 and the Wolf Piezolith 2200 lithotripters. The results for the two lithotripters were similar although the Dornier HM...