Roberto Dorta-Guerra

Roberto Dorta-Guerra
Universidad de La Laguna | ULL · Department of Mathematics, Statistics and Operations Research

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51
Publications
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171
Citations

Publications

Publications (51)
Article
Full-text available
The transactive response DNA-binding protein (TARDBP/TDP-43) influences the processing of diverse transcripts, including that of histone deacetylase 6 (HDAC6). Here, we assessed TDP-43 activity in terms of regulating CD4+ T-cell permissivity to HIV-1 infection. We observed that overexpression of wt-TDP-43 increased both mRNA and protein levels of H...
Article
In order to increase omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA) availability and to improve the design of rotifer's enrichment protocols for marine larvae production, the endogenous fatty acid (FA) metabolism of the marine rotifer, Brachionus plicatilis was determined. To this purpose, the in vivo ability of this species to inco...
Preprint
Full-text available
The transactive response DNA-binding protein (TDP-43) is an important regulator of mRNA, being reported to stabilize the anti-HIV factor, histone deacetylase 6 (HDAC6). However, little is known about the role of TDP-43 in HIV infection. In this work, we seek for the TDP-43 function on regulating CD4+ T cell permissibility to HIV infection. We obser...
Article
Full-text available
Background: Acute respiratory infections are one of the major causes of morbidity and mortality in children under 5 years in developing countries and are a challenge for the health system of these countries. In Cabo Verde, despite the lack of recent studies, data indicate that it affects thousands of children, being the fourth leading cause of infa...
Article
Full-text available
Trade credit is a crucial source of capital particularly for small businesses with limited financing opportunities. Inventory models considering trade credit financing have been widely studied. However, while there is extensive research on the single-vendor single-buyer inventory model allowing delays in payments, the systems where the vendor suppl...
Article
Full-text available
Transcriptional analysis of complex biological scenarios has been used extensively, even though sometimes the results of such analysis may prove imprecise or difficult to interpret due to an overwhelming amount of information. In this study, a large-scale real-time qPCR experiment was coupled to multivariate statistical analysis in order to describ...
Article
Westernized societies ingest an unhealthy high dietary omega-6/omega-3 fatty acid ratio of 20:1 or even higher. Seafood is the primary source of omega-3 long chain polyunsaturated fatty acids (LC-PUFA) for humans, mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are involved in a plethora of physiological and health-related...
Article
Full-text available
Angiostrongylus cantonensis is an emerging zoonotic nematode recognized as the leading cause of eosinophilic meningitis in the word. After its discovery in China, it was recorded in 30 countries worldwide. Recently, it has expanded to new areas such as South America and it has been recently found in the Atlantic island of Tenerife (Canary Islands)....
Article
Full-text available
Objectives Our previous study showed that long-term practitioners of Sahaja Yoga Meditation (SYM) had around 7% larger grey matter volume (GMV) in the whole brain compared with healthy controls; however, when testing individual regions, only 5 small brain areas were statistically different between groups. Under the hypothesis that those results wer...
Preprint
Transcriptional analysis of complex biological scenarios has been extensively used, even though sometimes results may prove imprecise or difficult-to interpret due to an overwhelming amount of information. In this study, a large-scale Real-time qPCR experiment was coupled to multivariate statistical analysis to describe the main immunological event...
Preprint
Full-text available
Objectives: Our previous study showed that long-term practitioners of Sahaja Yoga Meditation (SYM) had around 7% larger grey matter volume (GMV) in the whole brain compared with healthy controls; however, when testing individual regions, only 5 small brain areas were statistically different between groups. Under the hypothesis that those results we...
Article
Full-text available
Academic performance during the first year of university is correlated with future academic success and it is considered a determining factor in the reduction of dropouts. In this paper, we present a new academic performance indicator for the first term of first-year science degrees students at La Laguna University in Spain. We are interested in id...
Poster
Full-text available
El rendimiento académico durante el primer año de Universidad es crucial para el éxito académico futuro y se considera un factor determinante de las tasas de abandono. En este trabajo presentamos un nuevo indicador de rendimiento académico, básicamente la suma de las calificaciones obtenidas en las asignaturas aprobadas, aplicable para estudiantes...
Chapter
Full-text available
Several educational investigations have shown that the academic performance in the first year of university affects the success in subsequent years, which justifies the interest of analyzing the performance, during the first year, of new students in order to identify the factors that influence it. In the present work, a new indicator of this perfor...
Chapter
Full-text available
RESUMEN: Numerosas investigaciones educativas muestran que el rendimiento académico en el primer año de universidad incide en el éxito con el que se cursan los años subsiguientes, lo que justifica el interés de analizar el rendimiento, durante el primer curso, del alumnado de nuevo ingreso e identificar los factores que influyen en él. En el prese...
Preprint
Full-text available
Numerosas investigaciones educativas muestran que el rendimiento académico en el primer año de universidad incide en el éxito con el que se cursan los años subsiguientes, lo que justifica el interés de analizar el rendimiento, durante el primer curso, del alumnado de nuevo ingreso e identificar los factores que influyen en él. En el presente trabaj...
Article
Background: Maternal obesity is known to affect human milk composition. Long-chain polyunsaturated fatty acids (LCPUFA) are vital nutrients to the nervous system development and precursors of eicosanoids related to obesity (prostaglandin E2-PGE2-and leukotriene E4-LTE4). The aim of the present research was to study the lipid profiles, with particu...
Chapter
Full-text available
The School of Sciences of the University of La Laguna launched, in the academic year 2016/17, a Plan for the detection and attention of training deficiencies in Biology, Physics, Geology, Mathematics and Chemistry for incoming freshmen. This initiative is motivated by the observation that among the various variables that condition the academic perf...
Chapter
Full-text available
RESUMEN: La Facultad de Ciencias de la Universidad de La Laguna lanzó, en el curso 2016/17, un Plan de detección y atención de deficiencias formativas en Biología, Física, Geología, Matemáticas y Química para el alumnado de nuevo ingreso en el centro. Esta iniciativa estuvo motivada por la constatación de que entre las diversas variables que condi...
Presentation
Entre las investigaciones educativas está consolidada la idea de que el rendimiento previo de un estudiante es un buen predictor de su rendimiento futuro; en particular, el rendimiento académico en el primer año de universidad incide en el éxito con el que se cursan los años subsiguientes. De ahí el interés de analizar el rendimiento, durante el pr...
Poster
Full-text available
En este trabajo se presentan y discuten los perfiles y los resultados académicos del alumnado de nuevo ingreso en la Facultad de Ciencias (Grados en Biología, Ciencias Ambientales, Física, Matemáticas y Química) de la ULL, para los cursos 2015/16 y 2016/17, en función de la nota de admisión. Tales resultados serán comparados oportunamente con los q...
Presentation
Full-text available
Entre las investigaciones educativas está consolidada la idea de que el rendimiento previo de un estudiante es un buen predictor de su rendimiento futuro; en particular, el rendimiento académico en el primer año de universidad incide en el éxito con el que se cursan los años subsiguientes. De ahí el interés de analizar el rendimiento, durante el pr...
Preprint
Full-text available
La Facultad de Ciencias de la Universidad de La Laguna lanzó, en el curso 2016/17, un plan de detección y atención de deficiencias formativas en Biología, Física, Geología, Matemáticas y Química para el alumnado de nuevo ingreso en el centro. Esta iniciativa estuvo motivada por la constatación de que entre las diversas variables que condicionan el...
Presentation
Full-text available
The High School curricula in Spain have been involved in a big controversy in the last years, and finally this past course the total deployment of the Education General Law (LOMCE) has concluded. One of the main consequences of this new structure has been the variety of backgrounds of the new science students when they access to university. For man...
Conference Paper
Full-text available
La Facultad de Ciencias de la Universidad de La Laguna lanzó, en el curso 2016/17, un Plan de detección y atención de deficiencias formativas en Biología, Física, Geología, Matemáticas y Química para el alumnado de nuevo ingreso en el centro. Esta iniciativa estuvo motivada por la constatación de que entre las diversas variables que condicionan el...
Article
Full-text available
Omega-3 long change polyunsaturated fatty acids in higher plants are limited with just a few plant genus showing the accumulation of stearidonic acid (SDA) being also the longest and more unsaturated omega-3 fatty acid present. Echium acanthocarpum has been proven to be an efficient and attractive producer of SDA. Improved production of this fatty...
Article
In today's business transactions, vendors usually offer their buyers a delay period in payment. This strategy has benefits to the vendor since it attracts new buyers who consider the delay period as a type of price reduction. In addition, permissible delay in payments also is advantageous for the buyers since they do not have to pay the vendor imme...
Article
The focus of this paper is the construction of a new procedure based on the multiplicative algorithm in order to determining optimal experimental conditions for discriminating between two rival models. Even for moderate examples the calculation of T-optimal designs is not straightforward. There are no known specific iterative numerical techniques f...
Article
Species relative importance distribution pattern changes of the ground-beetle assemblages were analyzed along elevation strata of Tenerife Island. The species importance estimates were expressed in terms of (i) activity density, as total catching of ground-beetle adults obtained with pitfall traps over each elevation stratum for one year, and (ii)...
Article
Objective: To compare the ability of lung ultrasound and a clinical method in the confirmation of a selective bronchial intubation by left double-lumen tube in elective thoracic surgery. Material and methods: A prospective and blind, observational study was conducted in the setting of a university hospital operating room assigned for thoracic su...
Article
Objective To compare the ability of lung ultrasound and a clinical method in the confirmation of a selective bronchial intubation by left double-lumen tube in elective thoracic surgery. Material and methods A prospective and blind, observational study was conducted in the setting of a university hospital operating room assigned for thoracic surger...
Article
Full-text available
A variety of conditions (culture media, inocula, incubation temperatures) are employed in antifouling tests with marine bacteria. Shewanella algae was selected as model organism to evaluate the effect of these parameters on: bacterial growth, biofilm formation, the activity of model antifoulants, and the development and nanomechanical properties of...
Data
The additional information accessible on-line provides data presented in tables and figures of the different parameters recorded in this investigation at the other sampling times of the different culture growth curves, as well as additional data of the statistical analyses conducted and not present in the printed version of the publication.
Article
Full-text available
Fatty acids are of great nutritional, therapeutic, and physiological importance, especially the polyunsaturated n-3 fatty acids, possessing larger carbon chains and abundant double bonds or their immediate precursors. A few higher plant species are able to accumulate these compounds, like those belonging to the Echium genus. Here, the novel E. acan...
Article
Full-text available
The therapeutic and health promoting role of highly unsaturated fatty acids (HUFAs) from fish, i.e. eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3) are well known. These same benefits may however be shared by some of their precursors, the polyunsaturated fatty acids (PUFAs), such as stearidonic acid (SDA, 18:4 n-3). In...
Data
Full-text available
Tables (S1-S6) and Images S1a-f. Tables S1-S5 show the different sampling points not included in the main text. In each table the total lipid content and general fatty acid profiles (%) of the two cell lines of Echium acanthocarpum hairy roots at different sampling points are presented. n-6 and n-3 Δ6-Desaturation Indexes were calculated as 18:3n-6...
Data
Full-text available
Figures S1-S3. Figures S1-S3 show plots of PC1 and PC2 factor scores categorized by type of culture and by sampling points.
Article
The fatty acid profile of vegetable oils (VOs), together with the poor ability of marine fish to convert polyunsaturated fatty acids (PUFA) to highly unsaturated fatty acids (HUFA), lead to important changes in the nutritional value of farmed fish fed VO, which include increased fat and 18:2n-6 and reduced n-3 HUFA. Echium oil (EO) has a good n-3/n...
Article
Information in a statistical experiment is often measured through the determinant of its information matrix. Under first order normal linear models, the determinant of the information matrix of a two-level factorial experiment neither depends on where the experiment is centered, nor on how it is oriented, and balanced allocations are more informati...
Article
This paper provides closed form expressions for the sample size for two-level factorial experiments when the response is the number of defectives. The sample sizes are obtained by approximating the two-sided test for no effect through tests for the mean of a normal distribution, and borrowing the classical sample size solution for that problem. The...
Article
In multiperiod control one sequentially chooses the value of an input variable to keep an output variable close to a target value. At any stage the input variable has to be such that the output is close to target while at the same time it provides as much information as possible about the model that relates input and output, to help keep the output...
Article
Full-text available
D-optimal experiments for binary response data have been extensively studied in recent years. On the other hand two-level fractional factorials are often used as screening designs at the preliminary stage of an investigation when the outcome is continuous. We explore the performance of the one-half two-level experiments for a logistic model with th...
Article
The information matrix of a sequence of independent experiments is the sum of their information matrices but the value taken on that sequence by the real valued measures of the information based on that matrix is not the sum of the values they take on the individual experiments. Nevertheless, when information is measured through the determinant of...
Article
Full-text available
RESUMEN Contrario al esquema tradicional del tamaño muestral fijo cuando se usan experimentos factoriales fraccionales a dos niveles con respuesta binaria (defectuoso / no-defectuoso) se considera que cada combinación factorial es muestreada hasta que un número fijo de unidades defectuosas es observada, usando como respuesta el número total de unid...
Article
Full-text available
RESUMEN Se discute el problema de la estimación del tamaño muestral requerido para detectar cambios específicos cuando se utilizan experimentos factoriales fraccionales a dos niveles y el número de unidades defectuosas como respuesta, siguiendo una estructura similar a la propuesta de Bisgaard y Fuller. El problema es reformulado en términos de la...

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Projects (2)
Project
This is an Educational Innovation Project developed in the School of Sciences of the University of La Laguna during the academic courses 2016/17 and 2017/18, aimed to identify those variables that best correlate with the academic performance of newly admitted students in order to adopt measures oriented to reduce academic failure.
Project
Research, innovation, biosciences. Learning and teaching skills.