Robert Usher Newton

Robert Usher Newton
Edith Cowan University · Exercise Medicine Research Institute

BHMS(Hons), MHMS, PhD DSc

About

843
Publications
683,750
Reads
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41,117
Citations
Introduction
Professor of Exercise Medicine at Edith Cowan University, Perth, Western Australia. Current major research directions include: reducing decline in strength, body composition and functional ability in cancer patients; cancer related fatigue and the influence of exercise; exercise medicine and tumour biology. 470 refereed scientific journal articles, Scopus h-Index of 82 being cited 22,850 times. 2018 Career Achievement Award - Cancer Council WA 2019 West Australian Scientist of the Year.
Additional affiliations
January 2016 - February 2016
Edith Cowan University
Position
  • Associate Dean, Medical and Exercise Sciences
January 2016 - February 2016
Edith Cowan University
Position
  • Associate Dean, Medical and Exercise Sciences
January 2012 - present
The University of Queensland
Education
November 1993 - September 1998
Southern Cross University
Field of study
  • Exercise Physiology and Biomechanics
January 1989 - December 1992
The University of Queensland
Field of study
  • Biomechanics
January 1982 - December 1985
The University of Queensland
Field of study
  • Human Movement Studies

Publications

Publications (843)
Article
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Introduction: Exercise may positively alter tumour biology through numerous modulatory and regulatory mechanisms in response to a variety of modes and dosages, evidenced in pre-clinical models to date. Specifically, localised and systemic biochemical alterations produced during and following exercise may suppress tumour formation, growth and distri...
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Side effects accompanying androgen deprivation therapy (ADT), including sarcopenia, loss of bone mass and reduction in muscle strength, can compromise physical function, particularly in older patients. Exercise, specifically resistance training, may be an effective and cost-efficient strategy to limit or even reverse some of these adverse effects d...
Article
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To assess the effects of androgen deprivation therapy (ADT) on whole-body and regional muscle, fat and bone mass in men with prostate cancer without metastatic bone disease. Seventy-two men aged 44-88 years underwent spine, hip and whole-body dual-energy X-ray absorptiometry scans at baseline and after 36 weeks of ADT. The change in whole-body and...
Article
To examine the effect of progressive resistance training on muscle function, functional performance, balance, body composition, and muscle thickness in men receiving androgen deprivation for prostate cancer. Ten men aged 59-82 yr on androgen deprivation for localized prostate cancer undertook progressive resistance training for 20 wk at 6- to 12-re...
Article
Introduction: Prostate cancer is the most common cancer in men and patients treated with androgen deprivation therapy (ADT) experience unfavourbale changes in body composition and associated metabolic complications, which can increase the risk of cardiovascular disease. We examined the effect of a 6-month program of aerobic and resistance exercise...
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This article addresses several key issues that have been raised related to subjective training load (TL) monitoring. These key issues include how TL is calculated if subjective TL can be used to model sports performance and where subjective TL monitoring fits into an overall decision-making framework for practitioners. Regarding how TL is calculate...
Article
Introduction: Evidence regarding the role of exercise in pancreatic cancer (PanCa) is limited and is derived exclusively under tightly controlled research conditions. This study aimed to quantify adherence, adverse events, and changes in physical and psychological outcomes in any patients with PanCa referred to undertake exercise during non-surgic...
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Purpose While calls have been made for exercise to become standard practice in oncology, barriers to implementation in real-world settings are not well described. This systematic scoping review aimed to comprehensively describe barriers impeding integration of exercise into routine oncology care within healthcare systems. Methods A systematic lite...
Article
Kraemer, WJ, Caldwell, LK, Post, EM, Beeler, MK, Emerson, A, Volek, JS, Maresh, CM, Fogt, JS, Fogt, N, Häkkinen, K, Newton, RU, Lopez, P, Sanchez, BN, and Onate, JA. Arousal/stress effects of "Overwatch" eSports game competition in collegiate gamers. J Strength Cond Res XX(X): 000-000, 2022-To date, no physical response data are available for one o...
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Background Skeletal muscle loss is common in advanced cancer and is associated with negative outcomes. In malignant pleural mesothelioma (MPM), no study has reported body composition changes or factors associated with these changes. This study aimed to describe changes in body composition over time and its relationship with activity levels, dietary...
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Adults with Down syndrome are an underserved population at high risk for a host of different pathologies from aging and lack of activity. Purpose To examine the effects of a 10-week resistance training program on measures of motor behavior, cognitive function, mood, and physical fitness. Methods Participants ( n = 11) were men and women clinicall...
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Purpose Cancer-induced muscle wasting (i.e., cancer cachexia, CC) is a common and devastating syndrome that results in the death of more than 1 in 5 patients. Although primarily a result of elevated inflammation, there are multiple mechanisms that complement and amplify one another. Research on the use of exercise to manage CC is still limited, whi...
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Introduction Men who receive androgen deprivation therapy (ADT) for prostate cancer (PCa) are a vulnerable falls population due to the side effects of treatment. The purpose of this paper is to determine the cost-effectiveness of exercise in preventing falls and fractures for this high-risk population in Australia. Methods A decision analytic mode...
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Introduction Obese men with prostate cancer have an increased risk of biochemical recurrence, metastatic disease and mortality. For those undergoing androgen deprivation therapy (ADT), substantial increases in fat mass are observed in the first year of treatment. Recently, we showed that a targeted supervised clinic-based exercise and nutrition int...
Article
PURPOSE Androgen-deprivation therapy in patients with prostate cancer (PCa) is associated with considerable side effects and secondary comorbidities such as overweight/obesity and cardiovascular disease. The aim of this study was to investigate the effectiveness of an industry-led, treatment-integrated, community-based exercise program on outcomes...
Article
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Despite increasing popularity of cerebral palsy (CP) football (para football) worldwide, there are limited data available describing effective attacking strategies that lead to goals. The purpose of this research was to investigate the most frequent methods of ball repossession, distribution and movement patterns that successfully led to goals scor...
Article
Purpose: The aim of the present investigation was to determine whether a one-hour floatation-REST session could augment recovery from high-intensity resistance exercise (6 x10 back squats, 2 minutes rest) known to induce significant metabolic, adrenergic, and mechanical stress. Methods: Eleven healthy resistance-trained males (age: 22.5 ± 2.3 ye...
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Effects of eccentric (ECC) versus concentric (CON) strength training of the upper body performed twice a week for 10 weeks followed by detraining for five weeks on maximal force, muscle activation, muscle mass and serum hormone concentrations were investigated in young women (n = 11 and n = 12). One-repetition bench press (1RM), maximal isometric f...
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Indigenous Standpoint Theory forms the epistemological foundation for this study and methodological choices were made within this theoretical framework to ensure culturally responsive research processes that engaged the Indigenous agenda of self-determination and rights. The objectives of this research were to determine: (i) Indigenous perceptions...
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Although there is a large body of evidence documenting the benefits of engagement in formal volunteering among older people, research assessing the specific aspects of the volunteering experience that are associated with these benefits is limited. Accordingly, the objective of this study was to (i) examine the aspects of volunteering that predict i...
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Purpose of Review This review aims to provide an overview of the current evidence for the clinical utility of aerobic exercise therapy and discuss the practical considerations for prescribing exercise in the preoperative, intra-abdominal surgery setting. Recent Findings There is a strong physiological rationale for exercise medicine and the associ...
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Background Altering the systemic milieu through exercise has been proposed as a potential mechanism underlying exercise-driven tumour suppression. It is not yet known whether men with advanced prostate cancer can elicit such adaptations following a program of exercise. The purpose is to examine myokine levels of serum acquired from metastatic castr...
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Obesity and mental health disorders are rising simultaneously with shifting dietary behavior away from home cooking, toward typically nutrition-poor and energy-dense convenience meals. Food literacy strongly influences nutrition choices. Community-based cooking interventions target barriers to healthy eating and facilitate development of food liter...
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To systematically review and analyze the effects of resistance-based exercise programs on body composition, regional adiposity, and body weight in individuals with overweight/obesity across the lifespan. Using PRISMA guidelines, randomized controlled trials were searched in nine electronic databases up to December 2020. Meta-analyses were performed...
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Introduction Adequate, transparent, and consistent reporting of adverse events (AEs) in exercise oncology trials is critical to assess the safety of exercise interventions for people following a cancer diagnosis. However, there is little understanding of how AEs are reported in exercise oncology trials. Thus, we propose to conduct a scoping review...
Article
Issue addressed: Older adults are significantly less likely than their younger counterparts to engage in physical activity. Comprehensive policies to support healthy ageing thus need to include components encouraging greater participation in physical activity in later life. This study tested potential messages for use in health communication campa...
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Objective To evaluate the implementation of a multicomponent survivorship programme for men with prostate cancer and their carers. Design A single cohort study, guided by the RE-AIM framework. Setting Multiple health services in Australia. Participants Men with prostate cancer and their carers, and health professionals. Intervention A 12-month...
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Numerous epidemiological studies indicate that physical activity has a protective effect against colon cancer development and progression. Further, the relevant biological mechanisms where physical activity or exercise may improve survival have also been initially examined. In this review, we provide an overview of the epidemiological evidence to d...
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PURPOSE Exercise has been underutilized in people with advanced or incurable cancer despite the potential to improve physical function and reduce psychosocial morbidity, especially for people with bone metastases because of concerns over skeletal complications. The International Bone Metastases Exercise Working Group (IBMEWG) was formed to develop...
Article
Purpose: To perform a systematic review and network meta-analysis to investigate the most effective intervention for improving body composition outcomes in prostate cancer patients during or following treatment. Methods: A systematic search was undertaken in multiple databases from inception to December 2020. Randomized clinical trials examining th...
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Preliminary research has shown the effectiveness of supervised exercise-based interventions in alleviating sequela resulting from metastatic prostate cancer. However, many individuals encounter barriers that limit the uptake of face-to-face exercise. Technology-enabled interventions offer a distance-based alternative. This pilot study aimed to expl...
Article
Objective: To compare training and match loads for CP football athletes in a state-level development program to assess the specificity of training for competition in the para sport. Design: Time-motion analysis and heart-rate monitoring were applied during 20 training sessions of the Western Australia CP football 2017 training season, and seven...
Article
Songsupap, T, Newton, RU, and Lawsirirat, C. Balancing injury risk and power development by weighted jump squat through controlling eccentric loading. J Strength Cond Res 35(11): 2999–3005, 2021—Weighted jump squat (WJS) training is highly effective for increasing neuromuscular power but entails higher injury risk than traditional resistance traini...
Article
Overweight and obese men with prostate cancer are at an increased risk of disease recurrence, exacerbated treatment-related adverse effects, development of obesity-related comorbidities, earlier progression and development of metastatic disease, and higher all-cause and prostate cancer-specific mortality. The physiological mechanisms associating ob...
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To systematically review and analyse the effects of exercise on morphological and neuromuscular muscle quality (MQ) outcomes in older adults and assess a range of possible moderators that may affect the impact of exercise on MQ outcomes. Using PRISMA guidelines, randomised controlled trials were searched in CINAHL, EMBASE, LILACS, PubMed, SciELO, W...
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Objective: Little is known about how to effectively encourage higher levels of activity among older people. This study tested the effectiveness of a public service advertisement designed according to recommendations for communicating with older audiences and featuring five types of moderate-to-vigorous physical activity: tennis, line dancing, cycl...
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Background: Exercise may improve clinical and quality of life outcomes for men with prostate cancer. No randomized controlled trials (RCTs) have examined the feasibility, safety, and acceptability of remote exercise training in men with metastatic castrate-resistant prostate cancer (mCRPC). Methods: We conducted a pilot RCT (1:1:1 aerobic or res...
Article
Background Urinary incontinence is one of the most clinically relevant side effects in the treatment of prostate cancer patients. The aim of this systematic review and meta-analysis was to analyze the specific exercise effects of supervised versus unsupervised pelvic floor muscle exercise (PFME) and exercise volume on urinary incontinence status af...
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Purpose: Although several mechanisms have been proposed for the tumor-suppressive effect of exercise, little attention has been given to myokines even though skeletal muscle is heavily recruited during exercise resulting in myokine surges. We measured resting serum myokine levels before and after an exercise-based intervention and the effect of th...
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Physical exercise is increasingly recognized as a valuable treatment strategy in managing prostate cancer, not only enhancing supportive care but potentially influencing disease outcomes. However, there are limited studies investigating mechanisms of the tumor-suppressive effect of exercise. Recently, extracellular vesicles (EVs) have been recogniz...
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Objectives To assess the long-term effects of various exercise modes on psychological distress in men with prostate cancer on androgen deprivation therapy (ADT). Patients and methods 135 prostate cancer patients aged 43–90 years on ADT were randomized to twice weekly supervised impact loading and resistance exercise (ImpRes), supervised aerobic an...
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Introduction Exercise is one of several factors known to lower the risk of developing cancer, as well as improve outcomes in patients already diagnosed. People who exercise after cancer have lower rates of cancer complications, treatment toxicities, relapse and improved survival. This review highlights the supportive data and biochemical processes,...
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Purpose Although exercise medicine is recommended to counter treatment-related side-effects and improve health-related outcomes of patients affected by different cancers, no specific recommendations exist for patients with melanoma. As a result, we systematically examined the current evidence regarding the effects of physical activity and exercise...
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Background To systematically review and analyse the associations between fat and muscle mass measures with overall survival in men with prostate cancer. Methods A systematic search was conducted in CINAHL, Cochrane Library, EMBASE, PubMed, and Web of Science databases from inception to December 2020, while abstracts from the American Society of Cl...
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Background and objective Chronic medical conditions accumulate within individuals with age. However, knowledge concerning the trends, patterns and determinants of multimorbidity remains limited. This study assessed the prevalence and patterns of multimorbidity using extensive individual phenotyping in a general population of Australian middle-aged...
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Background Chronic obstructive pulmonary disease (COPD) is a disorder linked with a multitude of extra pulmonary manifestations (also known as treatable traits), including low bone mineral density (BMD). To date, no specific guidelines exist for the management of BMD in this population. Impact loading exercise has been identified as an intervention...
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Objective This review aims to provide a succinct and critical analysis of the current physical and mechanical demands of elite Australian football while examining lower-limb injury and the associated physical and kinanthropometric risk factors. Methods MEDLINE, PubMed, Web of Science and SPORTSDiscus electronic databases were searched for studies...
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Supervised exercise and nutrition programs can mitigate or reverse androgen deprivation therapy (ADT) induced fat mass (FM) gain, lean mass (LM) loss, and impaired physical function. It is unclear whether these benefits are retained following transition to self-management. This study examined the effect of a home-based weight maintenance program on...
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Background Radiotherapy is a commonly used treatment for prostate cancer; however, the side effects may negatively impact on quality of life and cause patients to be less physically active. While exercise has been shown to mitigate radiotherapy-related fatigue in men with prostate cancer during radiotherapy, other adverse effects of treatment such...
Article
Exercise is recognized by clinicians in the field of clinical oncology for its potential role in reducing the risk of certain cancers and in reducing the risk of disease recurrence and progression; yet, the underlying mechanisms behind this reduction in risk are not fully understood. Studies applying post-exercise blood serum directly to various ty...
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The primary objective of this investigation was to investigate the relationships between training load (TL), heart rate variability (HRV) and direct current potential (DC) with elite long jump performance prior to and during the 2016 Olympics Games. Sessional ratings of perceived exertion (sRPE), training duration, HRV and DC were collected from fo...
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We examined how summated training and match load measures relate to salivary immunological and hormonal profile changes in professional football players. Data were collected from 18 elite-level professional male football players from one English Championship team across a complete 40 wk competitive season. Daily training (micro-technology) and matc...
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Background: Complex, ongoing social factors have led to a context where metabolic syndrome (MetS) is disproportionately high in Aboriginal Australians. MetS is characterised by insulin resistance, abdominal obesity, hypertension, hypertriglyceridemia, high blood-sugar and low HDL-C. This descriptive study aimed to document physical activity levels,...
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Background Active treatments for prostate cancer are well known to result in several adverse effects such as fatigue, depression and anxiety symptoms, impacting the overall quality of life (QoL) and wellbeing of a considerable proportion of patients. Resistance-based exercise interventions have shown positive effects to reduce or mitigate these tre...