Rivo Andry Rakotoarivelo

Rivo Andry Rakotoarivelo
University of Fianarantsoa · Department of Medicine

Prof. MD

About

125
Publications
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204
Citations

Publications

Publications (125)
Article
Full-text available
A 47-year-old-man presented with orthostatic hypotension and cutaneous hyperpigmentation. He was infected with HIV and had cryptococcal meningitis, pulmonary TB, and lung abscess. Examination revealed cachexia and melanodermia on the cheeks, nose, and chin and around the mouth.
Article
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Post-malaria neurological syndrome is a rare complication of malaria. Typically, it occurs in case of severe malaria. Here we report a case in a Malagasy patient presenting a non-severe Plasmodium falciparum malaria complicated by post-malaria neurological syndrome. The management of such a syndrome is radically different from non-severe malaria. N...
Article
The authors describe clinical and epidemiologic characteristics of severe presentations of Rift valley fever (RVF) during the 2008 epidemic in Madagascar. The diagnosis was confirmed by RVF virus polymerase chain reaction (PCR), or detection of specifics antibodies by Elisa. Sixteen cases of severe RVF were recorded. The sex-ratio was 7/1 and media...
Article
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African histoplasmosis is a rare but not an exceptional condition and recently discovered in Madagascar. We report the fifth Malagasy case involving skin and nodes in an immunocompetent patient. Management of African histoplasmosis encountered many problems because of the availability of amphotericin B and cost of the biochemical tests in order to...
Article
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Few data are available about severe malaria in Madagascar. Our aims were to describe epidemiological, clinical and therapeutic aspects of severe malaria in patients in Antananarivo. We conducted a retrospective study from 1 March 2006 to 31 March 2008 at the infectious disease department. We recorded 61 cases of severe malaria among 1,803 in patien...
Article
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Introduction La Covid-19, est due au coronavirus SARS-COV 2 Nous présentons les résultats préliminaires d’une étude multicentrique des anomalies de fonction respiratoire observées chez les patients malgaches atteints de la Covid-19. Méthodes Il s’agit de patients non tabagiques hospitalisés suivis à l’hôpital CHU de Fianarantsoa, CHU de Toamasina,...
Article
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Background The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a new ribonucleic acid (RNA) beta-coronavirus, responsible for a worldwide pandemic. Very few cases of SARS-COV-2-related emphysema have been described, except among patients with chronic obstructive pulmonary disease. The thoracic CT scan is the key examination for the...
Article
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Background Mass drug administration (MDA) of praziquantel is one of the main control measures against human schistosomiasis. Although there are claims for including pregnant women, infants and children under the age of 5 years in high-endemic regions in MDA campaigns, they are usually not treated without a diagnosis. Diagnostic tools identifying in...
Article
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Introduction The current COVID-19 pandemic has impacted the entire world with increasing morbidity and mortality and has resulted in serious economic and social consequences. Assessing the burden of COVID-19 is essential for developing efficient pandemic preparedness and response strategies and for determining the impact of implemented control meas...
Article
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Introduction : La cirrhose est un problème de santé publique à Madagascar et source de morbi-mortalité élevée. L’objectif de notre travail était de décrire les caractéristiques épidémiologiques, cliniques, étiologique et évolutive des patients cirrhotiques au sein du Centre Hospitalier Universitaire Tambohobe Fianarantsoa. Patients et méthodes : Il...
Preprint
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Background: Mass drug administration (MDA) of praziquantel is one of the main control measures against human schistosomiasis. Although there are claims for including pregnant women, infants and children under the age of 5 years in high endemic regions in MDA campaigns, they are usually not treated without diagnosis. Diagnostic tools identifying inf...
Article
Full-text available
Early and fast detection of COVID-19 patients help limit the transmission and the widespread of the virus in the community and will have impact on mortality by reducing the incidence of infection among vulnerable people. Therefore, community-based screening is critical. We aimed to identify clinical signs and symptoms and epidemiological features t...
Article
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We propose a probabilistic approach to modelling the propagation of the coronavirus disease 2019 (COVID-19) in Madagascar, with all its specificities. With the strategy of the Malagasy state, which consists of isolating all suspected cases and hospitalized confirmed case, we get an epidemic model with seven compartments: susceptible (S), Exposed (E...
Article
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For Madagascar, with the uncertainty over vaccines against the novel coronavirus 2019 and its variants, non-pharmaceutical approach are widely used. Our objective is to propose a mathematical control model which will serve as a tool to help decision-makers in the strategy to be implemented to better face the pandemic. By separating asymptomatic cas...
Article
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Background: Schistosoma antigen detection in urine is a valuable diagnostic approach for schistosomiasis control programmes because of the higher sensitivity compared to parasitological methods and preferred sampling of urine over stool. Highly accurate diagnostics are important in low Schistosoma transmission areas. Pregnant women and young child...
Article
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Introduction La lèpre figure parmi les maladies tropicales négligées. À l’échelle mondiale, Madagascar est l’un des cinq pays les plus touchés par cette dernière. Elle est rare dans le monde mais engendre des complications inévitables, invalidantes et handicapantes en l’absence d’une prise en charge spécifique et à temps. De ce fait, un diagnostic...
Article
Introduction Les jeunes universitaires sont le groupe de population le plus sexuellement actif dans la population générale ; de ce fait, ils constituent un groupe à haut risque de contracter les infections sexuellement transmissibles, ainsi que l’infection à VIH. C’est pourquoi, une bonne connaissance, par cette tranche d’âge, des IST/VIH constitue...
Article
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Schistosoma antigen detection tests have a large potential for schistosomiasis control programs due to their ability to detect active and ongoing Schistosoma infections, their much higher sensitivity compared to microscopical methods, and the possibility to use non-invasive urine samples. Pregnant women and young children could especially benefit f...
Article
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Objectives To describe the epidemiological situation of the HIV/AIDS epidemic and to identify the main drivers for vulnerability in Madagascar. Design Literature review, qualitative research and situational analysis. Data sources Search of electronic bibliographic databases, national repositories of documentation from 1998 to 2018. Search keyword...
Article
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Cryptococcal meningoencephalitis (CM) remains the most prevalent invasive fungal infection worldwide. The main objective of this study was to describe the prevalence of CM and cryptococcal infection in HIV-infected patients in Madagascar. The secondary objectives were to assess the adjusted prevalence of CM according to clinical presentation and pa...
Article
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Introduction Zoonose des rongeurs due à Yersinia Pestis (YP) transmise à l’homme par les puces. Coccibacille Gram-aéro-anaérobie. Secrète une endotoxine. Maladie à déclaration obligatoire. Définition de l’Organisation mondiale de la santé (OMS) : cas suspect : symptômes cliniques + contexte épidémiologique. Cas probable : cas suspect + TDR + ou PCR...
Poster
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Issues: L'accès au soin est difficile pour les PVVIH dans les zones enclavées, loin des centres de référence de prise en charge ainsi que la réalisation de formations continues pour les personnels de santé dans ces zones. Pourtant, la couverture réseau et internet peut atteindre plus de 80% des malgaches, d'où l'intérêt de mise en place d'une plate...
Article
RATIONALE • Plague is a zoonosis of rodents, transmitted to humans by fleas • Due to Yersinia pestis , an enterobacterium, Gram-negative coccobacillus, facultative anaerobe Plague is a notifiable and a severe life-threatening disease .Major public health problem it is a persistent and re-emerging disease .Bubonic plague is the more frequent. In 201...
Article
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Background: Gastrointestinal cancers are among the top 10 cancers and causes of cancer death worldwide. Given the absence of cancer registry in Madagascar and absence of epidemiological study of gastrointestinal cancer in the province of Fianarantsoa, our aim was to describe the epidemiological aspect of gastrointestinal cancers at the University H...
Article
Introduction: Mass drug administration (MDA) of praziquantel is one of the main control measures against human schistosomiasis. Although pregnant women, infants and children under the age of 5 in high endemic areas should be considered for MDA, they are usually not treated without diagnosis. Diagnostic tools identifying infections at primary health...
Article
Full-text available
Introduction: World Health Organization data for Madagascar reveal that the nation's under age five mortality rate is 56/1000, and that its maternal mortality rate is 440/100,000. Malaria, leprosy, plague, and tuberculosis remain significant communicable disease threats. Malnutrition rates are improving but continue to impact negatively on the gen...
Article
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Background Adherence to antiretroviral therapy (ART) may be influenced by knowledge, perception and perception regarding ART. The purpose of this study was to assess knowledge, attitude/perception and practice regarding ART among people living with HIV/AIDS (PLHIV). Methods We conducted a cross-sectional survey to assess knowledge, attitudes, perc...
Poster
Introduction Madagascar fait partie des zones d’endémie bilharzienne du continent africain. La schistosomiase intestinale due à Schistosoma mansoni sévit sur la partie Est et Sud de l’île ainsi que sur les hautes terres centrales. Le fait est que malgré les mesures de lutte entreprises, l’épidémiologie de la bilharziose est en constant remaniement...
Article
Introduction Le test de marche de 6 minutes (TM6) est un bon test pour évaluer la dyspnée. Des études récentes ont démontré que le TLC3M est aussi reproductible que le TM6. Comparé au TM6, le TLC3M est peu coûteux, plus simple à réaliser en cabinet et utile pour l’évaluation de la dyspnée. Il est certainement plus adapté dans les pays en développem...
Article
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Key Clinical Message Hydrophobia is a clinical sign characteristic of human rabies. This sign occurs following paroxysmal contractions of pharynx responsible for hydrophobic spasms.
Article
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During the last few years, significant efforts have been made to improve access to antiretroviral therapy which led to dramatic reduction in AIDS-related events and mortality in HIV positive patients at the global level. However, current data in Africa suggested modest impact of widespread antiretroviral therapy scale-up especially regarding HIV-re...
Article
RATIONALE The 6-minute walk test (6MWT) is good for evaluating dyspnea. Recent studies have demonstrated that the 3MSST was as repeatable as the 6MWT. Compared to 6MWT, 3MSST is easier and low cost , feasible for office practice, and useful for the assessment of dyspnea; and is likely more easily adapted in developing countries such Madagascar. We...
Poster
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L’OMS a estimé à 31 000 le nombre des personnes vivant avec le VIH à Madagascar mais 2867 seulement sont suivis. Le dépistage et la lutte contre le VIH est surtout accès chez les populations clés car l’épidémie est dite concentrée à Madagascar. Mais les populations passerelles doivent être prises en compte aussi pour atteindre l’objectif « Zéro nou...
Poster
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L’OMS a estimé à 31 000 le nombre des personnes vivant avec le VIH à Madagascar mais 2867 seulement sont dans la file active. Le dépistage du VIH repose sur 2 stratégies à Madagascar: le dépistage volontaire et le counseling dépistage à l’initiative des soignants (CDIS). Le CDIS est insuffisant dans les hôpitaux et n’a jamais été proposé systématiq...
Poster
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Selon la Banque Mondiale, Madagascar occupe la 5ème place des pays les plus pauvres du monde et 81,8% des Malgaches vivent sous le seuil de pauvreté. Dans ce contexte, l’objectif zéro décès lié au SIDA ne pourra être atteint si les PVVIH ne peuvent être soignés correctement faute de moyen financier. Notre objectif est d’évaluer le coût direct de l’...
Presentation
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Les médecins référents (MedRef) sont les seuls à pouvoir prendre en charge les personnes infectées par le VIH (PVVIH), ils sont éparpillés dans tout Madagascar. La majorité d’entre eux travaille dans des zones isolées et est souvent confronté à des problèmes sur la prise en charge de leurs PVVIH. Ainsi, pour atteindre les objectifs 0 de l’OMS « zér...
Poster
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L’adhésion au traitement antirétroviral (TARV) est le garant du maintien du succès virologique chez les personnes vivant avec le VIH (PVVIH). La mauvaise connaissance du TARV comme la mauvaise perception du TARV ou les croyances liées au TARV peut influencer négativement l’observance thérapeutique. L’objectif de cette étude est d’évaluer la connais...
Poster
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L’ONUSIDA cible à l’horizon 2020 l’indétectabilité de la charge virale chez 90% des personnes vivant avec le VIH sous traitement antirétroviral (TARV). Cet objectif devra s’accompagner d’une large mise à l’échelle de la mesure de la charge virale (CV) en routine particulièrement dans les pays à ressources limitées. Depuis 2012, la mesure de la CV e...
Article
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Objective: To determine the epidemiological, clinical and evolutionary profile of severe malaria cases. Patients and Methods: Retrospective descriptive study carried out over a period of 36 months, bearing the cases of severe malaria in adults, treated at the Multipurpose Resuscitation Unit of the Tambohobe-Fianarantsoa Teaching Hospital. Results:...
Article
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Setting: A tertiary care hospital in Madagascar. Objective: To evaluate the feasibility of the implementation of a commercial rapid molecular diagnosis test (Xpert MTB/RIF) for the routine diagnosis of smear-negative or extra-pulmonary tuberculosis (TB) and its diagnostic accuracy, and to assess HIV prevalence in this population. Design: Prosp...
Article
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Background: The primary site of infection for Mycobacterium tuberculosis (Mtb) is the alveolar macrophages. However, Mtb can disseminate into other organs and causes extrapulmonary tuberculosis (EPTB). The diagnosis of EPTB is challenging due to relatively inaccessible infectious sites that may be paucibacillary and with clinical symptoms varying b...
Article
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We aimed to describe and to assess prognosis factors in tuberculous meningitis in adult patients.Methods.We p er for med a retrospective study of case records of adult patients. Patients classified as definite, probable, or possible tuberculous meningitis according to standardized definition criteria were included and assessed in the study.Results....
Article
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Background In Madagascar the epidemiology of cryptococcosis is poorly documented. The main objective of this study was to estimate the prevalence of Cryptococcal meningoencephalitis (CM) in Madagascar and to describe the presentation of the cases. Methods This is an observational transverse study conducted in the hospitals of Antananarivo and Toam...
Article
IntroductionLes pathologies hépatiques dues à l’infection chronique par le virus de l’hépatite B (VHB) et de l’hépatite C sont devenues actuellement les premiers facteurs de comorbidité et de mortalité chez les patients infectés par le VIH (PVVIH). À Madagascar, aucune étude n’a été effectuée concernant ces co-infections. Ainsi, notre objectif étai...
Article
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In order to assess prevalence and characteristics of antimicrobial self-medication in Antananarivo, Madagascar. We conducted a cross-sectional study among 101 patients in Department of Infectious Disease in the Academic Hospital Center of Antananarivo. Eighty-eight percent of patients had practiced self-medication whose 40% were employees of the pr...
Poster
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Overall prevalence of cryptococcal antigenemia (16.4%) and cryptococcal meningoencephalitis (15.1%) in Madagascar is high. Fever, headache, neck pain and night sweats were the most common signs observed. LFA CrAg test is confirmed to be reliable and cost effective; concordance of results compared to India ink and culture was 100%. CFR is unacceptab...
Book
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La maladie et le traitement antiretroviral bouleversent de plusieurs manières l’univers des personnes vivant avec le VIH. Nous avons effectué une étude transversale allant du 1er Juin 2007 au 30 Novembre 2007 chez les PVVIH sous traitement ARV et suivis au CHU/HJRB d’Antananarivo. Notre objectif était d’évaluer la qualité de vie des PVVIH. Trente u...
Article
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Abstract Introduction. The gastrointestinal bleeding remains a significant cause of morbidity and mortality. It is a medical and surgical emergency. In Madagascar, the gastrointestinal bleeding lays a major public health. The aim of our study vas to describe epidemioclinical, paraclinical and therapeutic aspects of gastrointestinal bleeding in ord...
Article
Full-text available
Cryptococcal meningoencephalitis is considered rare in HIV-negative individuals. In Madagascar, the epidemiology of cryptococcosis has not yet been well described, neither in immunocompetent nor in immunocompromised patients. We report here the first Malagasy detailed case of cryptococcal meningoencephalitis in a non-HIV immunocompromised adult pat...
Article
Background. In Africa, few data on the burden of fungal disease are published, but Madagascar is an exception. We have estimated the burden of serious fungal infections in Madagscar. Methods. We searched for existing data and estimated the incidence and prevalence of fungal diseases based on the populations at risk and availab le epid emiological d...
Article
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Introduction. Tuberculosis is highly endemic in Madagascar with 24 504 new cases notified in 2011. Tuberculous meningitis (TBM) is one of the most severe form of tuberculosis. However, it is not well known and probably underdiagnosed in Madagascar. In this study, we aimed to describe and assess short-term prognosis factors in TBM. Methods and Materi...
Article
Introduction L’hémodialyse est un acte invasif, et les hémodialysés sont exposés aux diverses complications. Les complications infectieuses constituent la deuxième cause de morbi-mortalité après les complications cardiovasculaires. Notre objectif est de décrire le profil bactériologique des infections chez les hémodialysés chroniques dans notre uni...
Article
Introduction : Very few studies have been conducted on antibiotic consumption in Madagascar. The objective of this study was to describe antibiotic consumption in a tertiary university hospital in Antananarivo, Madagascar to more clearly define good antibiotic use strategies. Materials and method : A one-day prevalence survey was conducted on 5 Apr...
Article
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This study assesses the nasal occurrence of β-lactamase-producing Enterobacteriaceae both in patients in a hospital department of infectious diseases at admission and in healthy Madagascan students and health care workers. Nasal swabs from 681 students, 824 health care workers, and 169 patients were obtained in Antananarivo, Madagascar, and transfe...