Ritu Sharma

• Master of Science
• Senoir Laboratory Technician at Chimera Transplant Reseach Foundation

Introduction: Numerous studies have concentrated on specific populations to explore the extensive polymorphism of class I and II HLA genes. This genetic diversity is crucial for various applications, such as advancing transplantation immunology, understanding genetic population patterns, and uncovering the pathways of different diseases. Objective:...

Numerous HLA allele relations with various diseases have been observed all over the world, including leukemia, aplastic anemia, and thalassemia. The current study looked at the frequency of HLA A, B, C, DRB1, and DQB1 loci with thalassemia to see if there was a correlation between the HLA allele and the disease. The study involved a total of 200 pa...

Introduction: Since HLA-B*15:02 is a biomarker for carbamazepine-induced Stevens- Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in certain Asian populations, the United States food and drug administration (USFDA) recommends HLA-B*15:02 screening before carbamazepine administration in Asian and other communities. Several published repo...

To survive from the life threatening diseases organ transplantation has become a solution. For transplantation of organs, the donor should be compatible with the recipient for a successful transplant, which is examined by performing compatibility testing like lymphocytotoxicity or flow cytometric assays. Lymphocytotoxicity assay is complement-depen...