Rino Franco

• PhD Student at Arcadia University

Background Anthracycline-mediated adverse cardiovascular events are among the leading causes of morbidity and mortality in patients with cancer. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) exert multiple cardiometabolic benefits in patients with/without type 2 diabetes, chronic kidney disease, and heart failure with reduced and preserved eje...

In this research, a multi-level statistic migration model for self-monitoring of the body generation picture is proposed. The approach can do a number of human generation tasks, such as garments style transfer, body posture migration, and pose transfer. Although the technique does not necessitate the manual matching of source-target image pairs for...

Background Anthracycline-mediated adverse cardiovascular events are among the leading causes of morbidity and mortality in patients with cancer. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) exert multiple cardiometabolic benefits in patients with/without type 2 diabetes, chronic kidney disease, and heart failure with reduced and preserved eje...

Background Doxorubicin-mediated adverse cardiovascular events are among the leading causes of morbidity and mortality in breast cancer patients. Sodium-glucose cotransporter 2 (SGLT2) inhibitors have recently been shown to be of therapeutic value in patients with type 2 diabetes, chronic kidney disease, and heart failure with reduced ejection fract...

Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Ricerca Corrente, Ministero della Salute. Background Doxorubicin-mediated adverse cardiovascular events are among the leading causes of morbidity and mortality in breast cancer patients. Sodium-glucose cotransporter 2 (SGLT2) inhibitor...

Background Doxorubicin–mediated adverse cardiovascular events are among the leading causes of morbidity and mortality in breast cancer patients. Sodium–glucose cotransporter 2 (SGLT2) inhibitors have recently been shown to be of therapeutic value in patients with type 2 diabetes, chronic kidney disease, and heart failure with reduced ejection fract...

Background: Metastatic colorectal cancer (mCRC) patients tend to have modest benefits from molecularly driven therapeutics. Patient-derived tumor organoids (PDTOs) represent an unmatched model to elucidate tumor resistance to therapy, due to their high capacity to resemble tumor characteristics. Materials and methods: We used viable tumor tissue...

This paper discusses estimating 3D scene flow directly from TensorFlow. The possibilities to represent the estimation of the scene flow became easily possible thanks to the large RGB-D data capture. Because of its potential applications in robotics the estimation of scene flow arouses a lot of interest in computer vision by researchers. We introduc...

This paper proposes a multi-level statistic migration model for self-monitoring of the body generation image, the method can achieve a variety of human generation tasks, including body posture migration pose transfer, the body clothes style migration, clothes style transfer, etc. While the method does not require the use of manual matching of image...

Objective: Our study aimed to confirm the expression of the endocannabinoid system in the human epithelial ovarian tumors, assessing the immunohistochemical expression of Cannabinoid Receptor Type 1 and Fatty Acid Amide Hydrolase in benign, borderline and malignant tumors. Materials and methods: Cannabinoid Receptor Type 1 and Fatty Acid Amide H...

Malignant mesothelioma (MM) is a rare aggressive neoplasm arising from mesothelial lining of body cavities, most commonly pleura and peritoneum. It is characterised by a poor prognosis and limited treatment options. A universally recognised risk factor for the development of MM is exposure to asbestos. However, evidence supporting a genetic suscept...

The pathologist is often called to define the origin of tumors through the help of ancillary studies, mainly immunohistochemical stainings. In this setting, the differential diagnosis between intestinal adenocarcinomas, other tumors with intestinal-type morphology, and adenocarcinomas metastatic to the bowel can be particularly difficult. In such c...

This paper builds a novel extracting method by sequentially read frame by frame images or video feed without consuming all of the resource of the equipment. This method calls a function between temporal change of brightness at a target pixel. This one can define the edge of each frame of the image at the local velocity. So we will compare the two i...

This paper builds a novel extracting method by sequentially read frame by frame images or video feed without consuming all of the resource of the equipment. This method calls a function between temporal change of brightness at a target pixel. This one can define the edge of each frame of the image at the local velocity. So we will compare the two i...

Gabor filters can extract multi-orientation and multiscale features from face images. Researchers have designed different ways to use the magnitude of the filtered results for face recognition: Gabor Fisher classifier exploited only the magnitude information of Gabor magnitude pictures (GMPs); Local Gabor Binary Pattern uses only the gradient infor...

The structural, energetic, and thermodynamic properties of the Co3 − sAlsO4 (s = 0, 1, 2, and 3) crystal family are studied using periodic DFT calculations. We provide a quantitative discussion of the cation distribution effect on the cell parameter, the oxygen Wyckoff position, the interatomic distances and the energies of the structures. It is de...

Problem statement: The effect of extracts from Neem ( Azadirachta indica ), Wormwood ( Artemisia absinthium ) and Tobacco ( Nicotiana tabacum ) with added copper sulfate, on female Boer goats infected with gastrointestinal parasites (GIN) was evaluated. Approach: Following initial screening for infection, animals were artificially infected with a m...

The goal of this study was to evaluate the effectiveness of garlic (Allium sativum L.) for controlling gastroin­testinal parasites in adult female Boer goats. The impact of garlic treatment in goats naturally infected with Haemonchus contortus and Coccidia was evaluated by measuring fecal egg counts, packed cell volume, FAMACHA scores, and body wei...

Structural, energetic and thermodynamic properties of CoAl2O4 and Co2AlO4 spinels are investigated using the density functional theory formalism. Thermal effects are incorporated by means of a non-empirical quasi-harmonic Debye-like model that allows us to study the influence of temperature on the relative stability of different cation distribution...

We discuss the use of magnetic resonance imaging (MRI) to reveal early fetal neurological involvement of cytomegalovirus (CMV) infection. A woman presented at 21 weeks of pregnancy with active CMV infection. Cerebral ultrasound examination had been normal. An MRI scan revealed a thickened germinal matrix, which was histologically confirmed, associa...

Quantum-mechanical static simulations of the high-pressure spinel phase of Si3N4 have been performed to determine the unit cell geometry and the equation of state from 0 to 50 GPa. The application of the Bader theory to the ab initio electron density leads to quantum consistent atomic charges and volumes, the crystalline bonding graph, and the pred...

Our study aimed to combine in vivo foetal cerebral magnetic resonance findings and histopathological analysis to chart details of the development and characteristics of the germinal matrix not disclosed by ultrasound, and to establish standard normal parameters for in vivo investigation. We enrolled pregnant women between the 18th and 23rd weeks of...

Congenital cytomegalovirus (CMV) infection may give rise to severe foetal damage: 40-50% of infants born to mothers with primary CMV infection become congenitally infected and of these 5-18% are symptomatic with a 30% mortality rate. Around 80% of surviving infants present central nervous system sequelae such as microcephaly, microgyria, impaired n...

In this study, structural and electronic properties of CoAl2O4 spinel are investigated for the first time by means of quantum chemical computational tools. Coupling supercell periodic calculations under the density functional theory formalism with a nonempirical quasi-harmonic Debye model, we examine the influence of temperature on the relative sta...

We report the results of a theoretical study of structural, electronic, and pressure-induced phase transition properties in ZnTe. Total energies of several high-pressure polymorphs are calculated using the density functional theory (DFT) formalism under the nonlocal approximation. Thermal effects are included by means of a nonempirical Debye-like m...

The equations of state and phase diagrams of the cubic spinel and two high-pressure polymorphs of MgAl2O4 have been investigated up to 65 GPa using density functional theory, the space-filling polyhedral partition of the unit cell, and the static approximation. Energy-volume curves have been obtained for the spinel phase, the recently observed calc...

A theoretical investigation of the MgAl 2 O 4 crystal response to high-pressure conditions has been carried out to determine its stability against decomposition towards MgO and f -Al 2 O 3 , and towards recently observed orthorhombic phases. We have evaluated total energy versus volume curves using the density functional formalism under the non-loc...

Calculations based on density functional theory (DFT) were performed on various structural isomers of methyl silsesquioxanes, [MeSiO 3/2 ] n where n) 4, 6, 8, 10, 12, 14, and 16, to study their structural and electronic properties. The calculated results find the stability of methyl silsesquioxanes, except [MeSiO 3/2 ] 4 , against fragmentation and...

The structure, geometry, and vibrational frequencies of several isomers of small group III−V (MX)n clusters (n = 1, 2, 3; M = Al, Ga, In; X = P, As) have been investigated using density functional theory. The results reveal the same behavior as in the nitride clusters for monomers and dimers. The Al trimers exhibit a D3h structure like the nitride,...

AlP) n , (AlAs) n , (GaP) n , (GaAs) n , (InP) n , and (InAs) n Clusters with n) 1, 2, 3 The structure, geometry, and vibrational frequencies of several isomers of small group III-V (MX) n clusters (n) 1, 2, 3; M) Al, Ga, In; X) P, As) have been investigated using density functional theory. The results reveal the same behavior as in the nitride clu...

Fractal image coding is a relatively new technique for compact image representation. The basic coding scheme exploits self-similarities between parts of the image and other parts in it at a different resolution. The various parts are consequences of a partition grid obtained by applying a splitting criterion to the image. We present an algorithm fo...

Simple algebraic equations show that the bulk compressibility in spinel-type compounds can be expressed by means of cation oxide polyhedral compressibilities and a term that accounts for the pressure effect on the internal oxygen position in the unit cell. The equations explain (i) the difference of compressibilities at octahedral and tetrahedral s...

Fractal image coding is a relatively new technique for compact representation of an image by exploiting self-similarities between parts of the image and other parts in it at a higher resolution. The various parts at different resolutions are consequences of a partition grid and splitting criterion applied to the image. We propose a partitioning cri...

The electronic structure, equilibrium geometry, and equation of state of Al2O3 in the α — Al2O3 and Rh2O3(II) phases have been determined by means of the ab initio perturbed ion method augmented by a recently developed non-empirical Debye-like model for describing the vibrational thermal effects. A systematic multidimensional optimization of the st...

at the Al 3+ and O 2Gamma sites. Earlier attempts were carried out by using empirical and theoretical rigid and shell--model pair potentials [1,2], whereas the most elaborated atomistic simulations in corundum [3,4], have made use of the potential induced breathing (PIB) model developed by Boyer et al. [5]. In contrast with other materials simulate...

We have recently developed a non-empirical Debye-like model for the inclusion of thermal effects in the equation of state (EOS) of solids. This model allows the calculation of many thermodynamical properties from the E-V relationship. We report the results of a theoretical investigation that explores the EOS of two ionic solids: MgF2 and Al2O3. The...

We report the results of a theoretical investigation that explores for the first time temperature effects on the pressure-volume relationship in corundum. The ionic interactions within the α-Al2O3 crystal are modelized using the electron gas formalism along with electronic wavefunctions that are allowed to relax with crystal strains. A non-empirica...

The local arrangement of a substitutional Cr3+ ion for an Al3+ ion in corundum is studied by means of first-principles pairwise simulations and quantum-mechanical ab initio Perturbed Ion calculations. Our investigation is organized in two steps. First, we determine the cohesive properties of the host lattice by calculating the set of four crystalli...

Substance P is present in intrinsic nerves in the intestine and in some extrinsic sensory nerves. It can be released from these nerves to act on the muscle layers and on other enteric neurons. Immunohistochemical studies show that the enteric substance P neurons are short and branch profusely to supply all intestinal layers. Pharmacological studies...

The sesquiterpene lactones melampodin and llβ,13-dihydromelampodin have been isolated from Melampodium heterophyllum.

Three eudesmanolides of Pluchea rosea were found to be structurally related to the eudesmane, cuauthemone, earlier reported from plants of the same genus.

Substance P-like immunoreactivity has been localized in whole mount preparations of the isolated layers of the guinea-pig ileum. Axons containing substance P formed dense networks around the nerve cells and ran in the primary, secondary and tertiary nerve bundles of the myenteric plexus. 3.6% of the nerve cell bodies of the myenteric plexus and 11....

The two quinone-methides, pristimerin and tingenone, have been isolated from the roots of Schaefferia cuneifolia. Both compounds strongly inhibit the germination of lentil seeds.

Acid extracts from both normal and extrinsically denervated ileum contained a compound which was indistinguishable from synthetic substance P; this compound was assayed by examining its contractile effect on the longitudinal muscle of segments of ileum in which receptors for acetylcholine and histamine were blocked. Contractions caused by the compo...

The desensitization of receptors for substance P in the longitudinal muscle of the guinea-pig ileum has been studied. Receptors for substance P in the muscle became desensitized in the presence of relatively large concentrations of synthetic substance P; a desensitizing concentration of substance P of 7.5 x 10(-9) M shifted the concentration-respon...

Desipramine and protriptyline were administered to anaesthetized rats by two consecutive intravenous infusions in order to obtain a peak level (first infusion) followed by lower steady state concentrations (second infusion) (Wagner, 1974). Theoretical plasma level time courses were confirmed experimentally. Desipramine and protriptyline were measur...

The relationship between plasma concentrations and cardiac effects of nortriptyline was studied in anaesthetized young and old rats. Nortriptyline was administered by two consecutive intravenous infusions which resulted in a peak plasma concentration followed by steady state values. Increasing infusion rates were followed by proportional increases...

The pharmacological effects of three tricyclic antidepressant agents (desipramine, protriptyline and doxepin) are evaluated in rat isolated atria in relation to their accumulation and efflux kinetics. The pharmacological effects studed are: inhibition of 1-3H-noradrenaline uptake, potentiation of 1-noradrenaline chronotropic response, and changes i...

Dialysable peptides (M. W. less than 12,000) were obtained by plasmin digests of purified bovine fibrinogen. The biological effects of these peptides were studied in rats in three different test systems: ADP-induced platelet aggregation, isolated atria contractility and vascular permeability. The effects induced by the peptides were: inhibition of...

Low-molecular weight dialysable peptides, obtained by plasmin degradation of purified bovine fibrinogen preparations, have been shown to increase the chronotropic activity of isolated rat atria. This effect was dose dependent and was inhibited by inhibitors of glycolysis (NaF and 2-deoxy-D-glucose), but not by an inhibitor of oxidative phosphorylat...

Dialysable peptides (< 5,000 M. W.) derived from plasmin digestion of bovine fibrinogen preparations (Kabi) exerted a marked positive chronotropic effect on isolated rat atria. This effect reached a peak within two to four minutes, lasted as a plateau during four to six minutes and then slowly disappeared. It was abolished by glycolytic inhibitors...

The uptake of imipramine-14C, desipramine-14C, amitriptyline-14C and chlorimipramine-14C was studied in rat isolated atria incubated in a medium containing concentrations of the drugs ranging from 10−8 to 10−5 M: the tissue levels were linearly related to the concentration in the incubation medium, the four lines sharing almost the same equation: a...