Richard Mayne

Richard Mayne
University of the West of England, Bristol | UWE Bristol · Department of Computer Science and Creative Technologies

PhD FIBMS FLS FHEA

About

83
Publications
23,390
Reads
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774
Citations
Citations since 2016
61 Research Items
680 Citations
2016201720182019202020212022020406080100120140
2016201720182019202020212022020406080100120140
2016201720182019202020212022020406080100120140
2016201720182019202020212022020406080100120140
Additional affiliations
May 2019 - August 2020
University of the West of England, Bristol
Position
  • Lecturer
January 2015 - May 2019
University of the West of England, Bristol
Position
  • Research Associate
Description
  • 3x postdocs in slime mould computing, biological nanoengineering and intracellular computing.
September 2013 - September 2016
University of the West of England, Bristol
Position
  • PhD Student
Description
  • Ph.D research project involving the fabrication of unconventional computing devices utilising slime mould Physarum polycephalum as an amorphous massively parallel computing substrate.
Education
September 2013 - September 2016
University of the West of England, Bristol
Field of study
  • Unconventional Computing
September 2011 - September 2012
September 2009 - September 2013
University of the West of England, Bristol
Field of study
  • Biomedical Sciences

Publications

Publications (83)
Article
Full-text available
Collision-based computing (CBC) is a form of unconventional computing in which travelling localisations represent data and conditional routing of signals determines the output state; collisions between localisations represent logical operations. We investigated patterns of Ca 2+-containing vesicle distribution within a live organism, slime mould Ph...
Article
Full-text available
The plasmodium of slime mould Physarum polycephalum has recently received significant attention for its value as a highly malleable amorphous computing substrate. In laboratory-based experiments, nanoscale artificial circuit components were introduced into the P. polycephalum plasmdodium to investigate the electrical properties and computational ab...
Article
Full-text available
The plasmodium of slime mould Physarum polycephalum behaves as an amorphous reaction-diffusion computing substrate and is capable of apparently 'intelligent' behaviour. But how does intelligence emerge in an acellular organism? Through a range of laboratory experiments, we visualise the plasmodial cytoskeleton - a ubiquitous cellular protein scaffo...
Article
Full-text available
Preprint: Please see final publication `Slime mould foraging behaviour as optically coupled logical operations', Int J Gen Sys, 2015. Physarum polycephalum is a macroscopic single celled plasmodial slime mould. We employ plasmodial phototactic responses to construct laboratory prototypes of NOT and NAND logical gates with electrical inputs/outputs...
Article
Slime mould Physarum polycephalum is a single cell which physically oscillates via contraction of actomyosin in order to achieve motility. Several of its apparently ‘intelligent’ behaviour patterns such as anticipatory responses to periodic stimuli have recently been attributed as functions of the coupling between the oscillating intracellular reac...
Article
This report describes a method to obtain multicellular shaped compartments made by lipids growing from a sponge‐like porous structure. Each compartment is several tens of micrometers in diameter and separated by membranes comprised of phospholipid and amphipathic molecules. The multi‐compartment structure spontaneously grew to a millimeter scale, d...
Article
The use of live organisms in electrically-coupled sensing devices has been suggested as an alternative low-cost, low-environmental footprint and robust technology for continuous monitoring and sensing applications. The utility of Chlorella vulgaris algae as living biosensor media inside liquid marbles (LMs), micro-wells and surface recesses is here...
Article
Full-text available
Background The potential to directly harness photosynthesis to make actuators, biosensors and bioprocessors has been previously demonstrated in the literature. Herein, this capability has been expanded to more advanced systems — Marimo Actuated Rover Systems (MARS) — which are capable of autonomous, solar powered, movement. Results We demonstrate...
Article
Fungal electronics is a family of living electronic devices made of mycelium bound composites or pure mycelium. Fungal electronic devices are capable of changing their impedance and generating spikes of electrical potential in response to external control parameters. Fungal electronics can be embedded into fungal materials and wearables or used as...
Preprint
Fungal electronics is a family of living electronic devices made of mycelium bound composites or pure mycelium. Fungal electronic devices are capable of changing their impedance and generating spikes of electrical potential in response to external control parameters. Fungal electronics can be embedded into fungal materials and wearables or used as...
Preprint
Full-text available
Fungi cells are capable of sensing extracellular cues through reception, transduction and response systems which allow them to communicate with their host and adapt to their environment. They display effective regulatory protein expressions which enhance and regulate their response and adaptation to a variety of triggers such as stress, hormones, l...
Article
Simulated crime scene investigation is an essential component of forensic science education, but its implementation is costly and poses challenges to accessibility; offering personal investigations in higher education scenarios is often impossible. Virtual reality (VR) is an emerging technology which offers exciting prospects for teaching and learn...
Preprint
Full-text available
Simulated crime scene investigation is an essential component of forensic science education , but its implementation poses challenges relating to cost, accessibility and breadth of experience. Virtual reality (VR) is an emerging technology which offers exciting prospects for teaching and learning, especially for imparting practical skills. We docum...
Preprint
p>In this manuscript, we report our ground-breaking result on development of artificial multicellular structures capable for neuron like spiking activity. These structures are self-growing ensembles of vesicles whose membranes are combinations of phospholipid and viscous amphipathic molecules. The vesicles grow from a porous gel, and an osmotic pre...
Article
A fungal colony maintains its integrity via flow of cytoplasm along mycelium network. This flow, together with possible coordination of mycelium tips propagation, is controlled by calcium waves and associated waves of electrical potential changes. We propose that these excitation waves can be employed to implement a computation in the mycelium netw...
Preprint
Full-text available
A fungal colony maintains its integrity via flow of cytoplasm along mycelium network. This flow, together with possible coordination of mycelium tips propagation, is controlled by calcium waves and associated waves of electrical potential changes. We propose that these excitation waves can be employed to implement a computation in the mycelium netw...
Article
Liquid marbles (LMs) are of growing interest in many fields, including microfluidics, microreactors, sensors, and signal carriers. The generation of liquid marbles is generally performed manually, although there has recently been a burst of publications involving 'automatic marble makers'. The characteristics of a LM is dependent on many things, in...
Article
A liquid marble is a liquid droplet coated by a hydrophobic powder. The liquid marble does not wet adjacent surfaces and therefore can be manipulated as a dry soft body. A Belousov‐Zhabotinsky (BZ) reaction is an oscillatory chemical reaction exhibiting waves of oxidation. We demonstrate how to make a photo‐sensor from BZ medium liquid marbles. We...
Article
Hypothesis: Tubulin is a key protein of the cytoskeleton, forming networks of microtubules (MTs). These networks are vital for many aspects of a cell, including intra-cellular transport. It has been suggested by others that this network could be responsible for sub-cellular information processing, which naturally raises the question of whether suc...
Article
Full-text available
Neuromorphic computing devices attempt to emulate features of biological nervous systems through mimicking the properties of synapses, towards implementing the emergent properties of their counterparts, such as learning. Inspired by recent advances in the utilisation of liquid marbles (microlitre quantities of fluid coated in hydrophobic powder) fo...
Article
Full-text available
Background: The green algae balls (Aegagropila linnaei), known as Marimo, are large spherical colonies of live photosynthetic filaments, formed by rolling water currents in freshwater lakes. Photosynthesis therein produces gas bubbles that can attach to the Marimo, consequently changing its buoyancy. This property allows them to float in the prese...
Preprint
Full-text available
A liquid marble is a liquid droplet coated by a hydrophobic power. The liquid marble does not wet adjacent surfaces and therefore can be manipulated as a dry soft body. A Belousov-Zhabotinsky (BZ) reaction is an oscillatory chemical reaction exhibiting waves of oxidation. We demonstrate how to make a photo-sensor from BZ medium liquid marbles. We i...
Preprint
We study electrical properties of Taxol-stabilised microtubule (MT) ensembles in a droplet of water. We demonstrate that the MT droplets act as electrical switches. Also, a stimulation of a MT droplet with a positive fast impulse causes oscillation of the droplet's resistance. The findings will pave a way towards future designs of MT-based sensing...
Article
Full-text available
As the extent to which aquatic environments are polluted with nano-scale objects is becoming known, we are presented with an urgent need to study their effects on various forms of life and to clear and/or detoxify them. A range of methods exist to these ends, but a lack of inter-study comparability arising from an absence of experimental standardis...
Preprint
Neuromorphic computing devices attempt to emulate features of biological nervous systems through mimicking the properties of synapses, towards implementing the emergent properties of their counterparts, such as learning. Inspired by recent advances in the utilisation of liquid marbles (microlitre quantities of fluid coated in hydrophobic powder) fo...
Article
Full-text available
Liquid marbles (LMs) have many promising roles in the ongoing development of microfluidics, microreactors, bioreactors, and unconventional computing. In many of these applications, the coalescence of two LMs is either required or actively discouraged, therefore it is important to study liquid marble collisions and establish parameters which enable...
Article
Full-text available
Actin is a cytoskeletal protein which forms dense, highly interconnected networks within eukaryotic cells. A growing body of evidence suggests that actin-mediated intra- and extracellular signalling is instrumental in facilitating organism-level emergent behaviour patterns which, crucially, may be characterised as natural expressions of computation...
Article
Full-text available
P-systems are abstract computational models inspired by the phospholipid bilayer membranes generated by biological cells. Illustrated here is a mechanism by which recursive liposome structures (multivesicular liposomes) may be experimentally produced through electroformation of dipalmitoylphosphatidylcholine films for use in ‘real’ P-systems. We fi...
Preprint
P-systems are abstract computational models inspired by the phospholipid bilayer membranes generated by biological cells. Illustrated here is a mechanism by which recursive liposome structures (multivesicular liposomes) may be experimentally produced through electroformation of dipalmitoylphosphatidylcholine (DOPC) films for use in `real' P-systems...
Book
Cilia are microscopic finger-like cell-surface organelles possessed by a great many eukaryotic organisms, including humans, whose purposes include generating local fluid movements via rhythmic whip-like beating and environmental sensing. Despite intense research efforts since their discovery by van Leeuwenhoek in the 1670's, several key questions r...
Chapter
Slime mould Physarum polycephalum is a large single cell capable of distributed sensing, concurrent information processing, parallel computation, and decentralised actuation. The ease of culturing and experimenting with Physarum makes this slime mould an ideal substrate for real-world implementations of unconventional sensing and computing devices....
Article
Full-text available
Cilia are finger-like cell-surface organelles that are used by certain varieties of aquatic unicellular organisms for motility, sensing and object manipulation. Initiated by internal generators and external mechanical and chemical stimuli, coordinated undulations of cilia lead to the motion of a fluid surrounding the organism. This motion transport...
Chapter
Full-text available
Shortest path problems are a touchstone for evaluating the computing performance and functional range of novel computing substrates. Much has been published in recent years regarding the use of biocomputers to solve minimal path problems such as route optimisation and labyrinth navigation, but their outputs are typically difficult to reproduce and...
Article
Full-text available
The aquatic unicellular organism Paramecium caudatum uses cilia to swim around its environment and to graze on food particles and bacteria. Paramecia use waves of ciliary beating for locomotion, intake of food particles and sensing. There is some evidence that Paramecia pre-sort food particles by discarding larger particles, but intake the particle...
Article
Full-text available
The nanotechnology revolution has allowed us to speculate on the possibility of hybridising nanoscale materials with live substrates, yet significant doubt still remains pertaining to the effects of nanomaterials on biological matter. In this investigation, we cultivate the ciliated protistic pond-dwelling microorganism Paramecium caudatum in the p...
Article
Liquid marbles (LMs) have recently attracted interest for use as cargo carriers in digital microfluidics and have successfully been implemented as signal carriers in collisionbased unconventional computing circuits. Both application domains require LMs to roll over substantial distances and to survive a certain number of collisions without degradin...
Article
The slime mould Physarum polycephalum has been used in developing unconventional computing devices for in which the slime mould played a role of a sensing, actuating, and computing device. These devices treated the slime mould rather as an active living substrate yet the slime mould is a self-consistent living creature which evolved for millions of...
Chapter
Full-text available
Plants are highly intelligent organisms. They continuously make distributed processing of sensory information, concurrent decision making and parallel actuation. The plants are efficient green computers per se. Outside in nature, the plants are programmed and hardwired to perform a narrow range of tasks aimed to maximize the plants’ ecological dist...
Article
Shortest path problems are a touchstone for evaluating the computing performance and functional range of novel computing substrates. Much has been published in recent years regarding the use of biocomputers to solve minimal path problems such as route optimisation and labyrinth navigation, but their outputs are typically difficult to reproduce and...
Preprint
We exploit chemo- and galvanotactic behaviour of Paramecium caudatum to design a hybrid device that allows for controlled uptake, transport and deposition of environmental micro- and nanoparticulates in an aqueous medium. Manipulation of these objects is specific, programmable and parallel. We demonstrate how device operation and output interpretat...
Article
Full-text available
The slime mould Physarum polycephalum has been used in developing unconventional computing devices for in which the slime mould played a role of a sensing, actuating, and computing device. These devices treated the slime mould rather as an active living substrate yet the slime mould is a self-consistent living creature which evolved for millions of...
Preprint
Full-text available
The slime mould Physarum polycephalum has been used in developing un-conventional computing devices for in which the slime mould played a role of a sensing, actuating, and computing device. These devices treated the slime mould rather as an active living substrate yet the slime mould is a self-consistent living creature which evolved for millions o...
Article
Unconventional computing is about breaking boundaries in thinking, acting and computing. Typical topics of this non-typical field include, but are not limited to physics of computation, non-classical logics, new complexity measures, novel hardware, mechanical, chemical and quantum computing. Unconventional computing encourages a new style of thinki...
Research
Full-text available
Book review, "Embryogenesis Explained" by Natalie and Richard (Dick) Gordon, World Scientific (USA), 2016. ISBN 978-981-4350-48-8. Published in International Journal of Unconventional Computing (2017), Vol 13, pp 83--84
Article
Motile cilia are cell-surface organelles whose purposes, in ciliated protists and certain ciliated vertebrate epithelia, include generating fluid flow, sensing and substance uptake. Certain properties of cilia arrays, such as beating synchronisation and manipulation of external proximate particulate matter, are considered emergent, but remain incom...
Article
Full-text available
We discuss possible designs and prototypes of computing systems that could be based on morphological development of roots, interaction of roots, and analog electrical computation with plants, and plant-derived electronic components. In morphological plant processors data are represented by initial configuration of roots and configurations of source...
Chapter
Slime mould Physarum polycephalum is a single-celled amoeboid organism known to possess features of a membrane-bound reaction–diffusion medium with memristive properties. Studies of oscillatory and memristive dynamics of the organism suggest a role for behaviour interpretation via sonification and, potentially, musical composition. Using a simple p...
Preprint
The nanotechnology revolution has allowed us to speculate on the possibilities of hybridising nanoscale materials with live substrates, yet significant doubt still remains pertaining to the effects of nanomaterials on biological matter. In this investigation we cultivate the ciliated protistic pond-dwelling microorganism Paramecium caudatum in the...
Preprint
Motile cilia are cell-surface organelles whose purposes, in ciliated protists and certain ciliated vertebrate epithelia, include generating fluid flow, chemosensation, mechanosensation and substance uptake. Certain properties of cilia arrays, such as beating synchronisation and manipulation of external proximate particulate matter, are considered e...
Article
Living architectures and green energy are hot topics of the applied sciences. They aim to develop buildings that co-live with their environment and co-habit with people they house. An ultimate goal would be to make every block in a building capable of producing energy. We present results of scoping, and somewhat illustrative, experiments on generat...
Article
This work illustrates behavior patterns and trajectories of a bio-inspired artificial platform induced by a cellular automata (CA)-based control strategy. The platform embeds both CA control as physical electronic architecture and a distributed hardware layer as effectors. In this work, we test both the functionality of the novel hardware’s compone...
Article
Lettuce seedlings are attracting interest in the computing world due to their capacity to become hybrid circuit components, more specifically, in the creation of living 'wires'. Previous studies have shown that seedlings can be hybridised with gold nanoparticles and withstand mild electrical currents. In this study, lettuce seedlings were hybridise...
Chapter
Slime mould Physarum polycephalum is a macroscopic amoeba-like organism whose ability to ‘compute’ the solutions to complex problems ranging from logic to computational geometry has led to its extensive use as an unconventional computing substrate. In slime mould computing devices—‘Physarum machines’— data may be imparted to the organism via stimul...
Chapter
We retrospectively examine and offer new perspectives on the hybridisation of slime mould Physarum polycephalum with metallic nanoparticles for the purpose of creating semi-organic, semi-artificial unconventional computing devices. Nanoparticle suspensions were successfully introduced into the plasmodium of P. polycephalum via feeding—i.e. exploita...
Chapter
We overview families of Boolean logical gates and circuits implemented in computer models and experimental laboratory prototypes of computing devices made of living slime mould Physarum polycephalum. These include attraction gates, based on chemo-tactic behaviour of slime mould; ballistic gates, employing inertial movement of the slime mould’s acti...
Chapter
Through a range of laboratory experiments, we measure plasmodial membrane potential via a non-invasive method and use this signal to interface the organism with a digital system. This digital system was demonstrated to perform predefined basic arithmetic operations and is implemented in a field-programmable gate array (FPGA). These basic arithmetic...
Chapter
Slime mould Physarum polycephalum is a macroscopic amoeba-like organism whose ability to ‘compute’ the solutions to complex problems ranging from logic to computational geometry has led to its extensive use as an unconventional computing substrate. In slime mould computing devices—‘Physarum machines’—data may be imparted to the organism via stimula...
Article
Full-text available
Slime mould Physarum polycephalum is a single cell visible by unaided eye. Let the slime mould span two electrodes with a single protoplasmic tube: if the tube is heated to approximately 40{\deg}C, the electrical resistance of the protoplasmic tube increases from 3 M{\Omega} to approximatively 10'000 M{\Omega}. The organism's resistance is not prop...