Ricardo De oliveira

Ricardo De oliveira
University of São Paulo | USP · Departamento de Cirurgia e Anatomia (Ribeirão Preto)

PhD, Associate Professor
Neurosurgeon and Researcher

About

195
Publications
46,089
Reads
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1,846
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Introduction
Associate Professor of the Department of Surgery and Anatomy of the Medical School of Ribeirão Preto, University of São Paulo. He holds a PhD in Medicine from the USP (2001), Post-doctorate at Hôpital Necker-Enfants Malades (Université Rene Descartes) 2001 -2002, FMRP-USP 2003-2004 (glycobiology of brain tumors). He is currently assistant physician of Neurosurgery. Lines of research: Solid Brain Neoplasia of Childhood and Glicobiology of Pediatric Brain Tumors.
Additional affiliations
June 2000 - present
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Position
  • Professor (Associate)
January 1989 - present
University of São Paulo
Position
  • Professor (Associate)

Publications

Publications (195)
Article
Full-text available
Background Pilocytic astrocytoma is the most frequent pediatric glioma. Despite its overall good prognosis, complete surgical resection is sometimes unfeasible, especially for patients with deep-seated tumors. For these patients, the identification of targetable genetic alterations such as NTRK fusions, raised as a new hope for therapy. The presenc...
Article
The enduring success of the European Course in Pediatric Neurosurgery, established 36 years ago by Maurice Choux, Concezio Di Rocco, and Karl Hovind, who organized it for the first time in Marseille, France in 1986, has motivated the propagation of similar courses in the Americas and Asia-Pacific regions. This project was strongly encouraged and en...
Article
We are deeply saddened by the passing of Dr. William Harkness. A gifted surgeon, a caring clinician, a visionary leader and devoted family man, William left an indelible impression on pediatric neurosurgery and the many people whose lives he touched. Dr. William was educated at Eton School and qualified in medicine in 1979, at the University of Bir...
Article
Background: Various approaches are used for decompressive surgeries in the thoracic spine depending on the location and consistency of the pathology, always avoiding manipulation of the thoracic spinal cord. Recently, there has been an effort to achieve adequate results and reduce morbidity with minimally invasive surgeries. Good outcomes and the...
Article
Full-text available
PurposeThe jugular and tympanic glomus are rare neoplasms in the general population, being even more uncommon in the pediatric population. There is considerable morbidity associated with both disease and treatment. Treatment is essentially surgical, carried out in recent years in a multidisciplinary manner using preoperative embolization associated...
Article
Aplasia Dermal Dysplasia (ADD) is an etiologically heterogeneous congenital abnormality having a circumscribed area of absent skin that involves any region of the body mainly the cranial vertex. The condition may involve only the superficial skin but also the subcutaneous tissue, bone, or even the dura. ADD can be isolated or associated with other...
Article
Full-text available
A scientific journal’s greatest responsibility is to ensure that all contributions accepted for publications are rigorously but fairly reviewed. The Editor-in-Chief and Archives of Pediatric Neurosurgery gratefully acknowledge the qualified and regular collaboration of renowned medical doctors and scientists who kindly devoted their time to constru...
Article
Full-text available
The practice of surgery is based on the technical capabilities of the surgeon (techne), their knowledge (episteme) and their capacity of judgment (phronesis). Surgeons face situations that call into question moral choices and face ethical difficulties in their daily practice The routine of being called to evaluate clinical cases in the hospital eme...
Chapter
This video segment shows the final step of twin separation and the technique of vault and skin reconstruction.
Chapter
This video segments shows the utility of 3D models reconstruction based on CT and MRI scans. The anatomy of dural sinuses is very well understood when showed in 3D model reconstruction.
Chapter
This video segments explains the technique of skin expanders to provide enough skin tissue available at the time of final separation. The rational for skin expanders placement is explained.
Chapter
This video segment shows further steps of venous separation and brain dissection.
Chapter
This video segments provides the conclusion of the complex surgical work peformed and offers insights on the surgical steps to perform in future cases.
Chapter
This video segment shows the earliest phase of separation that includes separation of dural sinuses and explains the utility of silastic sheets interposed to identify and keep well separated the dissection plans in view of further procedures.
Chapter
This video segment shows the early outcome and the earliest complications following the twin separation, as well as the strategy to deal with complications and resolving them.
Chapter
This video segment provides elements about the early outrcome of the two patients.
Chapter
This video segment includes the clinical history and the early radiological studies.
Chapter
This video segment shows further steps of venous separation and brain dissection to preparare the final separation of the twins.
Book
Conjoined twins who are classified as craniopagus (joined at the cranium) have a rare congenital anomaly and can be classified into ‘complete or ‘partial, depending on whether or not they have shared dural venous sinuses. The separation of craniopagus is a very rare and complex challenge needing detailed evaluation and planning.
Chapter
Astrocytomas are the most common type of primary brain tumors in adults and children. The recently Revised fourth Edition of World Health Organization (WHO) Classification of Central Nervous System Tumors has led to a paradigm shift concerning the understanding of the natural history and management of CNS tumors, shedding light to the importance of...
Article
Full-text available
Background: Jugular foramen paragangliomas (JFP) treatment represents a challenge for surgeons due to its close relationship with facial nerve (FN), lower cranial nerves (LCN), and internal carotid artery. Due to its hypervascularization, preoperative tumor embolization has been indicated. Methods: Retrospective analysis of the clinical evolutio...
Article
Full-text available
An unlikely idea became a reality in June 2019 when we gathered an enthusiastic group and started testing the platform & workflow by OJS/PKP thus turning an idea into something concrete. The next step would be choosing the name of the journal and creating the website. Finally, the choice of the national and international editorial board based on ac...
Article
Michel Zerah was born on May 22, 1956 in Paris, France. He finished his medical study in 1985 at Faculté de médecine de CRETEIL (Paris, France) and graduated in Neurosurgery in April, 1988. Quickly took over as head of Clinic-Assistant of Paris Hospitals, “Service de Neurochirurgie de l’hôpital de Bicêtre” (1989) and as university professor (1998)...
Article
Cavernous malformations are vascular malformations that can occur anywhere in the central nervous system (CNS). Giant cavernous malformations (GCM) are extremely rare in adults, especially in the posterior fossa. Herein, we described a 48-year-old male who presented with vertigo and postural instability for three months. Neuroimaging revealed a 131...
Article
Full-text available
Background: Meningiomas are the most frequent primary central nervous system (CNS) tumors. Their geographical and ethnic characteristics need to be known, in order to enable rational treatment. Objective: To investigate clinical and epidemiological aspects in a series of patients with meningiomas. Methods: Retrospective analysis on the demogra...
Article
Full-text available
Purpose Inhalation of perillyl alcohol (POH) recently emerged as an investigational promising antiglioma strategy. However, little attention has been paid to its therapeutic potential for other brain tumors, especially in the pediatric setting. Methods The effects of POH were explored in medulloblastoma cell models belonging to the SHH variant wit...
Article
The insular lobe is a complex structure constituting anatomic, cytoarchitectonic, and functional interface between the allocortex and the neocortex. This area is a part of a larger system that includes the orbitofrontal, temporopolar, and insular regions, constituting the paralimbic system or mesocortex. For a long time, the issue in studying this...
Article
The mysterious and suspicious death of the young Henry Borel on March 8, 2021 in Brazil brought up again the subject of child violence to the media. The child had multiple injuries in the abdominal cavity, pulmonary contusion, head trauma and other injuries incompatible with a domestic accident or fall in his room as reported by parents. Brazilian...
Chapter
Extent of resection is one of the major contributing factors for survival of glioblastoma patients. However, before this surgical goal may be contemplated, the patient with suspected glioblastoma must undergo a series of preoperative steps: to confirm this pathology as the most probable clinical hypothesis, to assess the extension of the lesion and...
Article
Background Flow diverters (FDs) are effective in the treatment of carotid aneurysms. Compared with carotid aneurysms, the treatment of distal intracranial aneurysms with FDs has been associated with a relatively high incidence of complications. Low thrombogenic modified-surface FDs may reduce ischemic complications and allow for the use of a single...
Article
Full-text available
PurposeSomatic mutations on H3 histone are currently considered a genetic hallmark for midline pediatric high-grade gliomas (HGGs). Yet, different tumor histologies have been occasionally described to carry these mutations. Since histone modifications can lead to major epigenetic changes with direct impact on prognosis and treatment, we thought to...
Article
The brainstem is defined as the portion of the neural axis between the diencephalon and the cervical spinal cord. Brainstem gliomas (BSGs) can occur anywhere within this region and account for 10% to 15% of primary pediatric intracranial tumors. The development of neuroimaging allied to the refinement of surgical tools, such as improved magnificati...
Article
On 11 March, the WHO confirmed coronavirus disease 2019 as a pandemic. The Director-General of the WHO called on governments to change its course by taking "urgent and aggressive action" (1). In terms of the number of deaths COVID-19 has caused 1.919.126 deaths, reported to WHO as of January 10, 2021. (https://covid19.who.int). The COVID-19 pandem...
Conference Paper
Background: Pediatric traumatic brain injury (TBI) is a serious social and economic problem. Emerging countries have 89% of the cases worldwide and lack relevant epidemiological studies on the subject. Objectives: Characterize the demographic, social and economic profiles of the pediatric population suffering TBI in Brazil. Methods: Data on the cas...
Article
Full-text available
A scientific journal’s greatest responsibility is to ensure that all contributions accepted for publications are rigorously but fairly reviewed. The Editor-in-Chief and Archives of Pediatric Neurosurgery gratefully acknowledge the qualified and regular collaboration of renowned medical doctors and scientists who kindly devoted their time to constru...
Article
The human brain contains around 86 billion nerve cells and about as many glial cells [1]. In addition, there are about 100 trillion connections between the nerve cells alone. While mapping all the connections of a human brain remains out of reach, scientists have started to address the problem on a smaller scale. The term artificial neural network...
Article
Full-text available
OBJECTIVES Coronavirus disease (COVID-19) is a potentially severe respiratory illness that has threatened humanity globally. The pediatric neurosurgery practice differs from that of adults in that it treats children in various stages of physical and psychological development and contemplates diseases that do not exist in other areas. The aim of thi...
Article
Full-text available
Glioblastoma (GBM) is the most common primary malignant neoplasm of the central nervous system and, despite the standard therapy; the patients' prognoses remain dismal. The miRNA expression profiles have been associated with patient prognosis, suggesting that they may be helpful for tumor diagnosis and classification as well as predictive of tumor...
Article
Full-text available
Low back pain (LBP) is a common condition. It is estimated that 84% of adults will present LBP symptoms at some point in their lives. Rarely, however, is LPB an indication of a serious medical condition, requiring further investigation. The treatment of non-specific LBP is based on non-pharmacological strategies, e.g., non-steroidal anti-inflammato...
Article
Full-text available
OBJECTIVE This guideline aims to analyze the effect of the sec- tion of the filum terminale in the treatment of Chiari malformation type I symptoms. RECOMMENDATION It is not possible to recommend the section of the filum terminale in the treatment of Chiari malfor- mation type I based on the findings of this system- atic review. The section of the...
Article
Introduction/background: Distraction osteogenesis (DO) with an external distraction device such as the rigid external distraction frame has become an established method for treating midface hypoplasia in faciocraniosynostosis. It allows for greater advancement of the midface in comparison with traditional Le Fort III osteotomies, associated or not...
Article
Full-text available
Introduction: Hydrocephalus is the most common neurosurgical condition among children worldwide and shunt diversion of the cerebral-spinal fluid (CSF) has been widely available. The aim of the present study was to perform a systematic review on types and models of shunt devices available and critically evaluate scientific evidence in favor of the u...
Article
James Tait Goodrich was born on April 16, 1946 in Portland, Oregon, United States, the son of Richard Goodrich and Gail (Josselyn) Goodrich. Dr. Goodrich served as a Marine officer during the Vietnam War, during which time he decided his next step would be to pursue a medical career. Not only was he an elite surgeon, but over the years he was also...
Article
Full-text available
Much controversy remains on the current management of Chiari I deformity (CID) in children, with many clinical, surgical and ethic-legal implications. The Brazilian Society of Pediatric Neurosurgery (SBNPed, in the Portuguese acronym) has put together a panel of experts to analyze updated published data on the medical literature about this matter a...
Article
Full-text available
We evaluated the potential effects of ATO in different pediatric SHH-MB cell lines (ONS-76: TP53-wild type; DAOY and UW402: TP53-mutated). MB cell lines molecular subgroup was confirmed and TP53 mutations were validated. Cell viability, clonogenicity and apoptosis were evaluated after ATO treatment at different concentrations (1–16 µM) alone or com...
Article
Germinomas represent the most frequent tumour type in the pineal region. However, the synchronous involvement of the suprasellar region, frequently termed bifocal intracranial germinoma (BFG) is quite rare. A literature search identified a further of 48 pediatric cases with a median age of 12.9 years. BFG is known to be highly radiosensitive. We pr...
Article
A seven years-old boy presented with headache and progressive drowsiness. MRI demonstrated obstruction at the foramen of Magendie and foramina of Luschka. Child underwent an endoscopic third ventriculostomy (ETV). The postoperative course was uneventful. MRI scan showed a marked decrease in the size of the ventricles, showing therefore that cerebro...
Article
Hydrocephalus cases were regularly described by Hippocrates, Galen, and early and medieval Arabian physicians, who believed that this disease was caused by an extracerebral accumulation of water. Operative procedures used in ancient times are neither proven by skull findings today nor clearly reported in the literature. Evacuation of superficial in...
Article
Robin Paul Humphreys was born on 16 October 1937 in Edmonton, Alberta, Canada. He was admitted to the University of Toronto, Faculty of Medicine, in 1956, became the Class President for the academic year 1957-58, and was awarded the Webster Scholarship in the year of his graduation (1962). His internship was of the rotatory variety, served at St. M...
Article
Posterior fossa (PF) tumors are among the most frequent primary neoplasms in children. Proximity to the fourth ventricle, and therefore cerebrospinal fluid (CSF) pathways, predisposes children with PF tumors to the development of obstructive hydrocephalus. Some patients with PF tumors require a permanent CSF diversion procedure prior to or after tu...
Article
Full-text available
The latest threat to global health is the ongoing outbreak of the respiratory disease that was recently given the name Coronavirus Disease 2019 (Covid-19). Covid-19 was recognized in December 2019 [1]. It was rapidly shown to be caused by a novel coronavirus that is structurally related to the virus that causes severe acute respiratory syndrome (SA...
Article
Full-text available
Objective: The main objective of neurosurgery is to establish safe and reliable surgical techniques. Medical technology has advanced during the 21st century, enabling the development of increasingly sophisticated tools for preoperative study that can be used by surgeons before performing surgery on an actual patient. Laser-printed models are a rob...
Article
Full-text available
The “isomorphic subtype of diffuse astrocytoma” was identified histologically in 2004 as a supratentorial, highly differentiated glioma with low cellularity, low proliferation and focal diffuse brain infiltration. Patients typically had seizures since childhood and all were operated on as adults. To define the position of these lesions among brain...
Article
A 5 months-old boy presented with sudden irritability, vomiting, drowsiness. Child recovery spontaneous and neurological examination was unremarkable Head magnetic resonance scans revealed a third ventricle cyst compatible with choroid plexus cyst. The boy underwent a ventricular endoscopy with total resection of a choroid plexus cyst confirmed by...
Article
A 12 years old boy presented with strabismus, left third nerve palsy (ptosis, mydriasis, downward and abducted eye), and vertical conjugate gaze paresis. A brain magnetic resonance image revealed a brainstem solid cystic tumor in the mesencephalic tegmentum, with compression of the aqueduct of Sylvius and associated supratentorial ventriculomegaly....
Article
Pineal region tumors pose certain challenges regarding to their resection: a deep surgical field, associated critical surrounding neurovascular structures, and narrow operative working corridor due to obstruction by the apex of the culmen. The authors describe a midline supracerebellar infratentorial approach that is routinely performed and was suc...
Article
A 6 year-old boy presented with progressive decrease of visual acuity in his left eye. Neurological examination revealed a left third nerve palsy. His ophthalmological assessment showed left amaurosis and right temporal hemianopia. Head magnetic resonance scans revealed a suprasellar parachiasmatic lesion causing compression of optic chiasm. The bo...
Article
Context Signs and symptoms of Cushing’s syndrome (CS) overlap with common diseases, such as the metabolic syndrome, obesity, osteoporosis, and depression. Therefore, it can take years to finally diagnose CS, though early diagnosis is important for prevention of complications. Objective The aim of this study was to assess the time span between firs...
Article
Purpose Symptomatic Chiari type I malformation (CM) is treated with posterior fossa decompression with/ without duroplasty. Few authors suggested cerebellar tonsil caudal migration due to a supposed “caudal traction” of cranial nerve structures in a so-called occult tethered cord syndrome. For these authors, filum terminale (FT) sectioning may impr...
Article
Full-text available
Objective The effectiveness of decompressive craniectomy (DC) in the context of neurocritical care in adult patients has been recently under debate. The aim of our study was to evaluate the impact of decompressive craniectomy in severe traumatic brain injury (TBI) in children, focusing on short and long-term neurological and neuropsychological outc...
Article
Full-text available
Introduction: Neuroendoscopy is particularly useful as an adjunct in the treatment of hydrocephalus. CSF physiology differs among neonates, children and adults leading to different and conflicting results in the treatment of hydrocephalus using neuroendoscopy. The aim of our study was to review the literature regarding to analyze predictive clinica...
Article
Full-text available
Background: Posterior fossa dermoid cysts are rare, benign lesions whose diagnosis can be quite challenging because of their slow growth and subsequent paucity of symptoms. We present herein an unusual case of recurrent cerebellar abscesses induced by an adjacent extradural dermoid cyst with a complete occipital dermal sinus. Methods: The authors...
Article
The Brazilian Society for Pediatric Neurosurgery has become mature since its foundation in 1999. The Brazilian pediatric neurosurgeons have been recognized around the world and have been playing an important role in the dissemination of high level knowledge. Medical journals will continue as a main vehicle of scientific information for years to co...
Article
Full-text available
Depressed skull fracture, also referred to as a "ping-pong ball" or "pond" fracture in neonates, is a common sign of traumatic brain injury in paediatric patients. The main causes of depressed skull fractures include labour and obstetric trauma in newborns and direct head trauma in older children. Skull depression rarely resolves spontaneously, and...
Article
Background: Endoscopic spinal surgery is becoming quite popular, and the pursuit of a training model to improve surgeons' skills is imperative to overcome the limited availability of human cadavers. Our goal was to determine whether the porcine spine could be a representative model for learning and practicing interlaminar percutaneous endoscopic l...
Article
Full-text available
Introduction: Hydrocephalus is a multifactorial disease, affecting the dynamics of cerebrospinal fluid (CSF) and leading to severe neurological impairment in children; in spite of the recent advances in hydrocephalus research, it has many physiopathological aspects that still remain poorly understood, especially after treatment. Objectives: To a...
Article
Full-text available
Next-generation sequencing platforms are routinely used for molecular assignment due to their high impact for risk stratification and prognosis in medulloblastomas. Yet, low and middle-income countries still lack an accurate cost-effective platform to perform this allocation. TaqMan Low Density array (TLDA) assay was performed using a set of 20 gen...