About
12
Publications
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Introduction
Post-doctoral researcher with interest in the field of oncology, radiation biology, Genetic engineering and molecular biology
Current institution
Additional affiliations
April 2020 - September 2022
Sanorva Biotech Pvt. Ltd.
Position
- R&D Manager
April 2018 - September 2018
Publications
Publications (12)
Angiotensin-converting enzyme 2 (ACE2) and neuropilin 1, a vascular endothelial growth factor (VEGF) receptor, were identified to bind to the SARS-CoV-2 spike receptor-binding domain (spike RBD). In silico analysis based on 3D structure, multiple sequence alignment, and molecular docking of second domain of soluble Flt-1 (sFlt-1) and spike RBD reve...
Radiation therapy is one of the most effective methods of tumor eradication; however, in some forms of neuroblastoma, radiation can increase the risk of secondary neoplasms, due to the ability of irradiated cells to transmit pro-survival signals to non-irradiated cells through vesicle secretion. The aims of this study were to characterize the vesic...
Many indigenous medicinal plants possess promising therapeutic properties, but experimental demonstration of specific active compound is lacking. Recent research findings suggest that bioactive fractions derived from a reverberated medicinal plant, namely, Helicteres isora (L.) possesses many therapeutic properties. Different plant extracts are kno...
Exposure of cells to ionizing radiation IR) induces generation of reactive oxygen species (ROS) which may damage vital cellular molecules if not detoxified. Man herbs are known to protect cells from deleterious effects of induced ROS due to their antioxidant (AOs) properties. It is observed that endogenous antioxidants like SOD, GSH and GPX have po...
In normal functioning of the cell, there is a balance between generation and neutralization of reactive oxygen species (ROS) by endogenous cellular defense machinery. Low levels of ROS inside the cells are required for normal functioning of the cell, which regulate signaling mechanisms involved in mitosis and apoptosis; excess of ROS production may...
Over the centuries, the natural sciecnes have grown into two major branches of physical and biological sciences. In fact, physical and mathematical sciences have empowered scientist to unravel the mysteries of nature including complexity of life. In modern era, an increasing number of scientist are addressing the basic questions related to life and...
