Renato Campanini

University of Bologna | UNIBO · Department of Physics and Astronomy DIFA

A definite trend in Biomedical Imaging is the one towards the integration of increasingly complex interpretative layers to the pure data acquisition process. One of the most interesting and looked-forward goals in the field is the automatic segmentation of objects of interest in extensive acquisition data, target that would allow Biomedical Imaging...

Dijet production has been measured in collisions at a nucleon-nucleon centre-of-mass energy of 5.02. A data sample corresponding to an integrated luminosity of 35 was collected using the Compact Muon Solenoid detector at the Large Hadron Collider. The dijet transverse momentum balance, azimuthal angle correlations, and pseudorapidity distributions...

Spectra of identified charged hadrons are measured in pPb collisions with the CMS detector at the LHC at √SNN = 5.02 TeV. Charged pions, kaons, and protons in the transverse-momentum range pT ≈ 0.1-1.7GeV/c and laboratory rapidity pipeypipe < 1 are identified via their energy loss in the silicon tracker. The average pT increases with particle mass...

A study of color coherence effects in pp collisions at a center-of-mass energy of 7TeV is presented. The data used in the analysis were collected in 2010 with the CMS detector at the LHC and correspond to an integrated luminosity of 36 pb-1. Events are selected that contain at least three jets and where the two jets with the largest transverse mome...

Measurements of Wγ and Zγ production in proton-proton collisions at s=7TeV are used to extract limits on anomalous triple gauge couplings. The results are based on data recorded by the CMS experiment at the LHC that correspond to an integrated luminosity of 5.0fb-1. The cross sections are measured for photon transverse momenta pTγ>15GeV, and for se...

A search for the production of heavy partners of the top quark with charge 5/3 is performed in events with a pair of same-sign leptons. The data sample corresponds to an integrated luminosity of 19.5fb-1 and was collected at s=8TeV by the CMS experiment. No significant excess is observed in the data above the expected background, and the existence...

Results are presented of a search for a "natural" supersymmetry scenario with gauge mediated symmetry breaking. It is assumed that only the supersymmetric partners of the top quark (the top squark) and the Higgs boson (Higgsino) are accessible. Events are examined in which there are two photons forming a Higgs boson candidate, and at least two b-qu...

Results are presented of a search for a "natural" supersymmetry scenario with gauge mediated symmetry breaking. It is assumed that only the supersymmetric partners of the top quark (the top squark) and the Higgs boson (Higgsino) are accessible. Events are examined in which there are two photons forming a Higgs boson candidate, and at least two b-qu...

The production of \( Y \)(1S), \( Y \)(2S), and \( Y \)(3S) is investigated in pPb and pp collisions at centre-of-mass energies per nucleon pair of 5.02 TeV and 2.76 TeV, respectively. The datasets correspond to integrated luminosities of about 31 nb−1 (pPb) and 5.4 pb−1 (pp), collected in 2013 by the CMS experiment at the LHC. Upsilons that decay...

A search for invisible decays of Higgs bosons is performed using the vector boson fusion and associated ZH production modes. In the ZH mode, the Z boson is required to decay to a pair of charged leptons or a b b-bar quark pair. The searches use the 8 TeV pp collision dataset collected by the CMS detector at the LHC, corresponding to an integrated l...

The production of a Z boson, decaying into two leptons and produced in association with one or more b jets, is studied using proton-proton collisions delivered by the LHC at a centre-of-mass energy of 7 TeV. The data were recorded in 2011 with the CMS detector and correspond to an integrated luminosity of 5 fb-1. The Z(ℓℓ) + b-jets cross sections (...

A bstract A search for the standard model Higgs boson decaying to a W-boson pair at the LHC is reported. The event sample corresponds to an integrated luminosity of 4.9 fb ⁻¹ and 19.4 fb ⁻¹ collected with the CMS detector in pp collisions at $ \sqrt{s} $ = 7 and 8 TeV, respectively. The Higgs boson candidates are selected in events with two or thre...

A search for three-jet hadronic resonance production in pp collisions at a centre-of-mass energy of 8 TeV has been conducted by the CMS Collaboration at the LHC with a data sample corresponding to an integrated luminosity of 19.4fb. The search method is model independent, and events are selected that have high jet multiplicity and large values of j...

The inclusive cross section for top-quark pair production measured by the CMS experiment in proton-proton collisions at a center-of-mass energy of 7 TeV is compared to the QCD prediction at next-to-next-to-leading order with various parton distribution functions to determine the top-quark pole mass, m pole t , or the strong coupling constant, α S....

Measurements of the top quark-antiquark (t ¯ t) spin correlations and the top quark polarization are presented for t ¯ t pairs produced in pp collisions at √s=8 TeV. The data correspond to an integrated luminosity of 19.5 fb−1 collected with the CMS detector at the LHC. The measurements are performed using events with two oppositely charged leptons...

Results are reported from a search for supersymmetry in pp collisions at a center-of-mass energy of 8 TeV, based on events with a single isolated lepton (electron or muon) and multiple jets, at least two of which are identified as b jets. The data sample corresponds to an integrated luminosity of 19.3 fb−1recorded by the CMS experiment at the LHC...

The production cross section for a W boson and two b jets is measured using proton-proton collisions at √s=7 TeV in a data sample collected with the CMS experiment at the LHC corresponding to an integrated luminosity of 5.0 fb-1. The W+bb- events are selected in the W→μν decay mode by requiring a muon with transverse momentum pT > 25 GeV and pseudo...

A peaking structure in the J/ψφ mass spectrum near threshold is observed in B →J/ψφK decays, produced in pp collisions at √s=7 TeV collected with the CMS detector at the LHC. The data sample, selected on the basis of the dimuon decay mode of the J/ψ, corresponds to an integrated luminosity of 5.2 fb. Fitting the structure to an S-wave relativistic...

Constraints are presented on the total width of the recently discovered Higgs boson, ΓH, using its relative on-shell and off-shell production and decay rates to a pair of Z bosons, where one Z boson decays to an electron or muon pair, and the other to an electron, muon, or neutrino pair. The analysis is based on the data collected by the CMS experi...

Rapidity distributions are presented for events containing either a Z boson or a photon with a single jet in proton-proton collisions produced at the CERN LHC. The data, collected with the CMS detector at sqrt(s) = 7 TeV, correspond to an integrated luminosity of 5.0 inverse femtobarns. The individual rapidity distributions of the boson and the jet...

A bstract A study of proton-proton collisions in which two b hadrons are produced in association with a Z boson is reported. The collisions were recorded at a centre-of-mass energy of 7 TeVwith the CMS detector at the LHC, for an integrated luminosity of 5.2 fb ⁻¹ . The b hadrons are identified by means of displaced secondary vertices, without the...

A search for anomalous production of events with three or more isolated leptons and bottom-quark jets produced in pp collisions at √s=8 TeV is presented. The analysis is based on a data sample corresponding to an integrated luminosity of 19.5 fb(-1) collected by the CMS experiment at the LHC in 2012. No excess above the standard model expectations...

Searches for anomalous top quark-antiquark production are presented, based on pp collisions at √s=8 TeV. The data, corresponding to an integrated luminosity of 19.7 fb−1, were collected with the CMS detector at the LHC. The observed ttbar invariant mass spectrum is found to be compatible with the standard model prediction. Limits on the production...

Measurements of the differential and double-differential Drell-Yan cross sections are presented using an integrated luminosity of 4.5(4.8) inverse femtobarns in the dimuon (dielectron) channel of proton-proton collision data recorded with the CMS detector at the LHC at sqrt(s) = 7 TeV. The measured inclusive cross section in the Z-peak region (60-1...

A measurement of W+W- production in pp collisions at is presented. The data were collected with the CMS detector at the LHC, and correspond to an integrated luminosity of 4.92 +/- 0.11 fb(-1). The W+W- candidates consist of two oppositely charged leptons, electrons or muons, accompanied by large missing transverse energy. The W+W- production cross...

An inclusive search for supersymmetric processes that produce final states with jets and missing transverse energy is performed in pp collisions at a centre-of-mass energy of 8 TeV. The data sample corresponds to an integrated luminosity of 11.7 fb−1 collected by the CMS experiment at the LHC. In this search, a dimensionless kinematic variable, α T...

The first measurement of the electroweak production cross section of a Z boson with two jets (Zjj) in pp collisions at \( \sqrt{s}=7 \) TeV is presented, based on a data sample recorded by the CMS experiment at the LHC with an integrated luminosity of 5 fb−1. The cross section is measured for the ℓℓjj (ℓ = e, μ) final state in the kinematic region...

Results of searches for heavy stable charged particles produced in pp collisions at \( \sqrt{s} \) = 7 and 8 TeV are presented corresponding to an integrated luminosity of 5.0 fb−1 and 18.8 fb−1, respectively. Data collected with the CMS detector are used to study the momentum, energy deposition, and time-of-flight of signal candidates. Leptons wit...

A measurement of the λ lifetime using the decay λ , was recorded with the CMS experiment at the Large Hadron Collider using triggers that selected dimuon events in the J/ψ mass region. The λ lifetime is measured to be 1.503 ± 0.052 (stat.) ± 0.031 (syst.) ps. [Figure not available: see fulltext.] © 2013 Cern for the benefit of the CMS collaboration...

A measurement of the λ lifetime using the decay λ , was recorded with the CMS experiment at the Large Hadron Collider using triggers that selected dimuon events in the J/ψ mass region. The λ lifetime is measured to be 1.503 ± 0.052 (stat.) ± 0.031 (syst.) ps. [Figure not available: see fulltext.] © 2013 Cern for the benefit of the CMS collaboration...

We deduce approximate equations of state from experimental measurements in proton-proton and proton-antiproton collisions. Thermodynamic quantities are estimated combining the measure of average transverse momentum vs pseudorapidity density dN/deta with the estimation of the interaction region size from measures of Bose Einstein correlation, or fro...

The authors presented a novel system for automated nodule detection in lung CT exams. The approach is based on (1) a lung tissue segmentation preprocessing step, composed of histogram thresholding, seeded region growing, and mathematical morphology; (2) a filtering step, whose aim is the preliminary detection of candidate nodules (via 3D fast radia...

The average transverse momentum dependence on multiplicity shows in many experiments at center of mass energies ranging from 22 to 7000 GeV a slope change at a charged particle rapidity density constant within systematic uncertainties. We find correlated signals which together with the slope change may indicate a transition to a new mechanism of pa...

We have developed a SPEMT (Single Photon Emission MammoTomography) scanner that is made up of two cameras rotating around the pendulous breast of the prone patient, in Vertical Axis of Rotation (VAoR) geometry. Monte Carlo simulations indicate that the device should be able to detect tumours of 8 mm diameter with a tumour/background uptake ratio of...

States of volcanic activity at Mt Etna develop in well-defined regimes with variable duration from a few hours to several months. Changes in the regimes are usually concurrent with variations of the characteristics of volcanic tremor, which is continuously recorded as background seismic radiation. This strict relationship is useful for monitoring v...

In this work, gray‐scale invariant ranklet texture features are proposed for false positive reduction (FPR) in computer‐aided detection (CAD) of breast masses. Two main considerations are at the basis of this proposal. First, false positive (FP) marks surviving our previous CAD system seem to be characterized by specific texture properties that can...

A novel invariant texture classification method is proposed. Invariance to linear/non-linear monotonic gray-scale transformations is achieved by submitting the image under study to the ranklet transform, an image processing technique relying on the analysis of the relative rank of pixels rather than on their gray-scale value. Some texture features...

Metastases have been widely thought to arise from rare, selected, mutation-bearing cells in the primary tumor. Recently, however, it has been proposed that breast tumors are imprinted ab initio with metastatic ability. Thus, there is a debate over whether 'phenotypic' disease progression is really associated with 'molecular' progression. We profile...

We describe a stand-alone software utility named TREMOrEC, which carries out training and test of a Support Vector Machine (SVM) classifier. TREMOrEC is developed in Visual C++ and runs under Microsoft Windows operating systems. Ease of use and short time processing, along with the excellent performance of the SVM classifier, make this tool ideal f...

A system for automatic recognition of different volcanic activity regimes based on supervised classification of volcanic tremor is proposed. Spectrograms are calculated from volcanic tremor time-series, separated into four classes, each assumed as representative of a different state of volcanic activity, i.e., pre-eruptive, eruptive, lava fountains...

We have developed a tomograph for single photon emission imaging (SPECT) of the breast for the detection of small size tumors. The SPECT is mounted on a ring that is rotating around the breast with the patient in prone position. The breast will be imaged by two opposing detector heads of approximately 5 Â 15 cm 2 each, with a field of view about 13...

In a high-statistics experiment at the CERN-ISR we analyze the variation of the average transverse momentum in fixed rapidity intervals as a function of the multiplicity density of charged particles produced in proton-proton collisions at √s = 31, 44 and 62 GeV. The average transverse momentum depends on both rapidity y and charged multiplicity den...

IGHV3-21-using chronic lymphocytic leukemia (CLL) is a distinct entity with restricted immunoglobulin gene features and poor prognosis and is more frequently encountered in Northern than Southern Europe. To further investigate this subset and its geographic distribution in the context of a country (Italy) with both continental and Mediterranean are...

We have developed a compact single photon emission mammotomography (SPEMT) scanner capable of imaging the breast for the detection of small size (T1b) tumors. The scanner has a vertical-axis-of-rotation (VAOR) geometry, in which two gamma cameras orbit around a pendulous breast of a prone patient. The SPECT system is rotating around the vicinity of...

This work is developed within the framework of a larger project, which aims to develop a multimodal CT-SPET system dedicated to breast imaging. The goal of this paper is to optimize the choice of the various parameters involved in the design of a SPET system dedicated to breast imaging. In particular, we simulated different collimators, different t...

The purpose of this study was to perform a complete evaluation of three pieces of clinical digital mammography equipment. Image quality was assessed by performing physical characterization and contrast-detail (CD) analysis. We considered three different FFDM systems: a computed radiography unit (Fuji "FCR 5000 MA") and two flat-panel units, the ind...

Continuous seismic monitoring has achieved a key position in monitoring active volcanoes. However, it comes with the problem of a huge quantity of data difficult to handle. Automatic pattern recognition techniques have proven effective in seismic data processing and, consequently, have been increasingly implemented to solve different tasks. In this...

B-CLL is a apparently homogeneous disease with variable clinical courses, which can be foreseen by the presence of mutated (M) or unmutated (UM) IgVH genes and the expression of prognostic markers, including CD38. Since a correlation between high CD38 and UM IgVH gene configuration has been described, we performed GEP to identify the gene signature...

We applied an automatic pattern recognition technique, known as Support Vector Machine (SVM), to classify volcanic tremor data recorded during different states of activity at Etna volcano, Italy. The seismic signal was recorded at a station deployed 6 km southeast of the summit craters from 1 July to 15 August, 2001, a time span encompassing episod...

Leukemia is one of the leading journals in hematology and oncology. It is published monthly and covers all aspects of the research and treatment of leukemia and allied diseases. Studies of normal hemopoiesis are covered because of their comparative relevance.

10076 Background: The highly heterogeneous clinical courses of B-CLL can be foreseen by investigating IgVH gene mutations or expression of specific prognosticators. Gene and surface-antigen expression profilings (GEP and SEP) have been both employed for identifying molecules of prognostic relevance in B-CLL. Methods: i) GEP - Purified B-CLL cells f...

A novel approach to the detection of masses and clustered microcalcification is presented. Lesion detection is considered as a two-class pattern recognition problem. In order to get an effective and stable representation, the detection scheme codifies the image by using a ranklet transform. The vectors of ranklet coefficients obtained are classifie...

Studies of gene expression profiling have been successfully used for the identification of molecules to be employed as potential prognosticators. In analogy with gene expression profiling, we have recently proposed a novel method to identify the immunophenotypic signature of B-cell chronic lymphocytic leukemia subsets with different prognosis, name...

The classification of tumoral masses and normal breast tissue is targeted. A mass detection algorithm which does not refer explicitly to shape, border, size, contrast or texture of mammographic suspicious regions is evaluated. In the present approach, classification features are embodied by the image representation used to encode suspicious regions...

Studies of gene expression profiling (GEP) have been successfully used for the identification of molecules to be employed as potential prognosticators. With the aim of identifying the immunophenotypic profile of B-CLL subsets with different prognoses, we investigated by flow cytometry the expression of 36 surface antigens in 117 cases, 113 with sur...

With the aim of identifying the immunophenotypic profile of B-cell chronic lymphocytic leukemia (B-CLL) subsets with different prognosis, we investigated by flow cytometry the expression of 36 surface antigens in 123 cases, all with survivals. By analyzing results with unsupervised (hierarchical and K-means clustering) algorithms, three distinct im...

A prototype forPosLLTL EmisLTL Mammography, the YAP-PEM,is under development within a collaboration of the ItalianUniversFfifiC ofPisF Ferrara, and Bologna. The aimis to detect breas lessCU withdimensLFC of 5 mm in diameter, and with asLwU:fi activity ratio of 10:1 between the cancer andbreas tissT The YAP-PEMis composC of two sCTxwwCBU detectionhe...

A prototype for Positron Emission Mammography, the YAP-PEM, is under development within a collaboration of the Italian Universities of Pisa, Ferrara, and Bologna. The aim is to detect breast lesions, with dimensions of 5 mm in diameter, and with a specific activity ratio of 10:1 between the cancer and breast tissue. The YAP-PEM is composed of two s...

In this work, we present a novel approach to mass detection in digital mammograms. The great variability of the appearance of masses is the main obstacle to building a mass detection method. It is indeed demanding to characterize all the varieties of masses with a reduced set of features. Hence, in our approach we have chosen not to extract any fea...

The capability of the scintimammography to diagnose subcentimeters sized tumors was increased by the employment of a dedicated gamma camera. The introduction of small field of view camera, based on pixellated scintillation array and position sensitive photomultiplier, allowed to enhance the geometric spatial resolution and contrast of the images du...

Current CAD systems always demand better performance, both in terms of the best sensitivity-specificity tradeoff and of the processing time. In order to decrease the false positive rate and to increase the time responsiveness of our CAD system, we present a powerful algorithm that performs an intra-breast segmentation. Starting from a digital mammo...

A novel featureless approach to the detection of masses and microcalcifications has been adopted, based on a Support Vector Machine (SVM) classifier. This method does not rely on any feature extraction task; on the contrary, the algorithm automatically learns to detect the lesions by the examples presented to it during the training phase. Our techn...

A new gamma camera dedicated to scintimammography (single photon emission mammography-SPEM) now has a full-breast field of view. One can clinically examine a mildly compressed breast with a cranio-caudal-like projection as one would in X-ray mammography. This camera is based on pixelated scintillation arrays and position sensitive photomultiplier t...

Compact gamma cameras based on arrays of compact Position Sensitive Photomultipliers (PSPMTs) (Hamamatsu R7600–C8/12) were recently developed by several research groups. The previous generation of dedicated gamma cameras (5in. PSPMT) demonstrated the clinical benefit and general diagnostic value for functional breast imaging in comparison with conv...

The aim of this paper is to investigate the properties of a clinical FFDM unit (Giotto - Image MD, IMS Italy). The digital detector consists of a flat panel using the amorphous selenium technology (ANRAD Corporation, Canada). The active area of the imager is 17.4 cm 23.9 cm (20482816 pixels) with a pixel pitch of 85 m. The direct conversion of X-ra...

In this paper we present a novel approach to mass detection in digital mammograms. The great variability of the masses appearance is the main obstacle of building a mass detection method. It is indeed demanding to characterize all the varieties of masses with a reduced set of features. Hence, in our approach we decide not to extract any feature, fo...