Renan Pereira de Lima

• Master of Pharmacy
• Federal University of Ceará

Together with obesity and type 2 diabetes, metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global epidemic. Activation of the complement system and infiltration of macrophages has been linked to progression of metabolic liver disease. The role of complement receptors in macrophage activation and recruitment in MASLD re...

Lonchocarpus sericeus (Poir.) Kunth ex DC., Fabaceae, is traditionally used to treat stomach disorders and constipation. Previous studies examined its anti-inflammatory, antinociceptive, and hepatoprotective properties, but its potential as a gastroprotective agent remains unexplored. This study aimed to investigate the gastroprotective and gastric...

A Farmácia Clínica (FC) abrange as práticas farmacêuticas voltadas para a otimização da farmacoterapia, buscando melhores resultados clínicos, minimizando os riscos e custos envolvidos em sua utilização, além de estimular a prática do uso racional de medicamentos. Assim, este trabalhoteve como finalidade avaliar a influência e evolução nacional dos...

Five unusual kaurane diterpenes, designated as bezerraditerpenes A-E (1-5), along with six known ones (6-11), were isolated from the hexane extract of the stems of Erythroxylum bezerrae. Their structures were elucidated based on the interpretation of the NMR spectroscopy, mass spectrometry, and X-ray diffraction analysis. The anti-inflammatory pote...

This study aimed to evaluate the effect of proteinase K on mature biofilms of dermatophytes, by assays of metabolic activity and biomass. In addition, the proteinase K-terbinafine and proteinase K-griseofulvin interactions against these biofilms were investigated by the checkerboard assay and scanning electron and confocal microscopy. The biofilms...

Nonalcoholic fatty liver disease (NAFLD), characterized by hepatosteatosis and steatohepatitis, is intrinsically related to obesity. Our previous study reported on the anti-obese activity of a,b-amyrin (AMY), a pentacyclic triterpene isolated from Protium heptaphyllum. This study investigated its ability to prevent fatty liver and the underlying me...

Insulin resistance is closely related to the metabolic syndrome that is characterized by a set of diseases that include obesity, dyslipidemia and diabetes mellitus. Due to a considerable increase of these diseases in the last decades, several studies are being carried out worldwide aiming to find solutions to prevent and to treat insulin resistance...

Dietary fiber intake plays an important role in the prevention of obesity. This study aimed to investigate the effect of cashew fiber without low molecular weight compounds (CABwc) on obesity prevention and metabolomics in a murine model of diet-induced obesity. Mice were fed a chow diet (CD), high-fat diet (HFD) or a high-fat diet supplemented wit...

Objetivo: Avaliar a utilização de medicamentos psicotrópicos no sistema penitenciário. Metodologia: Os dados foram obtidos através de levantamento prospectivo, observacional, quantitativo e descritivo. Foram analisados 30 prontuários de indivíduos condenados por sentença judicial, coletados no Instituto Psiquiátrico Governador Stênio Gomes localiza...

The objective of this study was to evaluate the effect of cashew fiber wheter or not associated with low molecular weight compounds on lipid profile, abdominal adiposity, glycemia and insulinemia and serum concentration of ghrelin and leptin hormones from normal mice. We evaluated the cashew fiber in its integral form (IcF) and the cashew fiber aft...

Introdução: O impacto da violência no desenvolvimento urbano tem merecido destaque. As consequências da exposição à violência mais especificamente aos homicídios e ao uso de drogas incluem alterações fisiológicas, neurológicas e de âmbito interpessoal. Objetivo: Este estudo teve como objetivo verificar a prevalência de exposição à violência comunit...