Renad Alyautdin

Renad Alyautdin
Federal State Institution "Scientific Center of Expertise of Medical Products" | REGMED · Centre for Expertise of Drug Safety

Doctor of Medicine

About

18
Publications
2,617
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
57
Citations
Introduction
Renad Alyautdin currently works at the Centre for Expertise of Drug Safety, Federal State Institution "Scientific Center of Expertise of Medical Products". Renad does research in Human Biology and Molecular Biology. Their current project is 'Drugs safety monitoring'.

Publications

Publications (18)
Article
Introduction. Poly(lactide-co-glycolide) (PLGA) nanoparticles (NPs) are biodegradable and biocompatible drug carriers and competent at delivering neuroprotective agents to the brain following peripheral administration. Brain-derived neurotrophic factor (BDNF) could provide neuroprotection in brain insult particularly ischaemic injury. We tested the...
Article
Full-text available
Poly (lactide‑co‑glycolide) (PLGA) nanoparticles (NPs) are biodegradable carriers that participate in the transport of neuroprotective drugs across the blood brain barrier (BBB). Targeted brain‑derived neurotrophic factor (BDNF) delivery across the BBB could provide neuroprotection in brain injury. We tested the neuroprotective effect of PLGA nanop...
Article
Full-text available
Purpose: Increased lenticular oxidative stress and altered calcium/magnesium (Ca/Mg) homeostasis underlie cataractogenesis. We developed a liposomal formulation of magnesium taurate (MgT) and studied its effects on Ca/Mg homeostasis and lenticular oxidative and nitrosative stress in galactose-fed rats. Methods: The galactose-fed rats were topically...
Article
Full-text available
Purpose Increased lenticular oxidative stress and altered calcium/magnesium (Ca/Mg) homeostasis underlie cataractogenesis. We developed a liposomal formulation of magnesium taurate (MgT) and studied its effects on Ca/Mg homeostasis and lenticular oxidative and nitrosative stress in galactose-fed rats. Methods The galactose-fed rats were topically...
Article
Full-text available
Currently, traumatic brain injury (TBI) is the leading cause of death or disabilities in young individuals worldwide. The multi-complexity of its pathogenesis as well as impermeability of the blood-brain barrier (BBB) makes the drug choice and delivery very challenging. The brain-derived neurotrophic factor (BDNF) regulates neuronal plasticity, neu...
Article
Резюме: Средства передовой терапии (СПТ) представляют гетерогенную группу медицинских продуктов, объединенную необходимостью особого регу- лирования их обращения. К СПТ относят средства для генной терапии, сред- ства терапии соматическими клетками, средства тканевой инженерии и комбинированные средства передовой терапии. В рамках Европейского агент...
Article
Резюме: C60 фуллерен, состоящий из 60 атомов углерода, представляет собой зам- кнутую структуру, включающую 12 пентагональных и 20 гексагональных граней. Ди- аметр молекулы составляет 0,71 нм. Фуллерены являются третьим, после графита и алмаза, состоянием углерода. Фуллереновые наночастицы плохо всасываются из ЖКТ, и это затрудняет исследование зак...
Article
Age-related macular degeneration is the main cause of loss of sight in the world. This review presents a current view on modern drugs used for the treatment of macular degeneration. A comparison effectiveness and safety profile of bevacizumab, ranibizumab, and pegaptanib aflibercept enables us to conclude that each of these compounds has its own ad...
Article
Neurotrophin BDNF is essential for the development and functioning of the CNS. Numerous studies have shown that many diseases of the central nervous system, including Parkinson's disease, Alzheimer's disease and other neurodegenerative diseases are accompanied by decline in level of the brain BDNF. At the same time, increasing the concentration of...
Article
The paper describes the principal lines of development of nanocarriers for medical substances, morphological groups of nanocarriers, and influence of the physical and chemical properties of matrix substances on the key stages of the technological process. Technology aspects of manufacturing nanocarriers, differences in the conditions and techniques...
Article
DRUGS TARGETING THROUGH THE BLOOD-BRAIN BARRIER: MAGINOT LINE, OR MAGIC SESAME?Review is devoted to the analysis of the evolution of methods of drug delivery through the blood-brain barrier. Modern concepts on the structure and function of the BBB, the molecular structure of the "tight junctions", characteristic traits of the metabolism of endothel...

Network

Cited By

Projects

Project (1)