Rebecca Baker

Rebecca Baker
University College London | UCL · Institute of Cardiovascular Science

Master of Research

About

6
Publications
534
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4
Citations

Publications

Publications (6)
Article
Full-text available
Medical therapies achieve their control at expense to the patient in the form of a range of toxicities, which incur costs and diminish quality of life. Magnetic resonance navigation is an emergent technique that enables image‐guided remote‐control of magnetically labeled therapies and devices in the body, using a magnetic resonance imaging (MRI) sy...
Article
Full-text available
Minimally Invasive Image‐Guided Ablation Concept An artist's impression of the minimally invasive image‐guided ablation (MINIMA) concept, whereby the magnetic field gradients generated by an MRI scanner are used to navigate a ferromagnetic thermoseed through tissue to a target, where it is remotely heated to deliver thermal ablation. More details c...
Article
Full-text available
Astrocytes play crucial and diverse roles in brain health and disease. The ability to selectively control astrocytes provides a valuable tool for understanding their function and has the therapeutic potential to correct dysfunction. Existing technologies such as optogenetics and chemogenetics require the introduction of foreign proteins, which adds...
Article
Magnetomechanical Stimulation Magnetomechanical stimulation enables remote and selective control of brain cell activity without any need for genetic modification. Antibody‐functionalized magnetic particles are targeted to the mechanosensitive astrocytes and a magnetic field is applied to activate signaling pathways that regulate a wide range of bra...
Article
Full-text available
Targeted drug delivery systems aim to increase therapeutic effect within the target tissue or organ, while reducing off-target toxicity associated with systemic delivery. Magnetic drug targeting has been shown to be an effective strategy by manipulating therapeutics inside the body using a magnetic field and an iron oxide carrier. However, the effe...

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