Rayyan Tutunji

Leiden University | LEI · Department of Clinical Psychology

Depression is characterized by a loss of positive and pronounced negative memory bias, which persists after remission. While theoretical accounts of depressive realism, emotional inertia, and mood-congruency substantiate the compelling evidence of weak positive memory in depression, they cannot fully explain negative memory bias in depression. We u...

Intensive longitudinal research has become increasingly popular in the social and clinical sciences in recent years. However, this popularity has brought about many challenges for both methodological and empirical researchers, including challenges regarding measurement. In this study, we are particularly interested in the assessment of the reliabil...

Ecological momentary assessment (EMA) increases ecological validity but can be burdensome. To reduce this burden and to better understand psychological constructs in daily life, a growing chorus of voices has called for augmenting or replacing EMA data with data passively collected from wearable devices. It is thus critical to investigate the quali...

The use of ecological momentary assessment (EMA) data to study individuals in their everyday lives is popular in many areas of social and life sciences. At the same time, EMA data sets are complex, the psychometric properties of EMA items are often not investigated systematically, and scales are often neither standardized nor validated beyond their...

Our current understanding of the human stress response and its role in health, resilience, and (psycho)pathology stems largely from acute stress studies in controlled laboratory settings. Comparability of findings across these individual studies is comprised, as sample size are often small, between-individual variation in the stress response is lar...

Background Increasing efforts toward the prevention of stress-related mental disorders have created a need for unobtrusive real-life monitoring of stress-related symptoms. Wearable devices have emerged as a possible solution to aid in this process, but their use in real-life stress detection has not been systematically investigated. Objective We a...

Controlled laboratory stress induction procedures are very effective in inducing physiological and subjective stress. However, whether such stress responses are representative for stress reactivity in real life is not clear. Using a combined within-subject functional MRI laboratory stress and ecological momentary assessment stress paradigm, we inve...

Physiological noise has been shown to have a large impact on the quality of functional MRI data, especially in areas close to fluid-filled cavities and arteries, such as the brainstem. Commonly, physiological recordings during scanning are transformed with methods such as RETROICOR and used as nuisance regressors in general linear models to remove...

BACKGROUND Increasing efforts toward the prevention of stress-related mental disorders have created a need for unobtrusive real-life monitoring of stress-related symptoms. Wearable devices have emerged as a possible solution to aid in this process, but their use in real-life stress detection has not been systematically investigated. OBJECTIVE We a...

[This corrects the article DOI: 10.1371/journal.pone.0260952.].

The endeavor to understand the human brain has seen more progress in the last few decades than in the previous two millennia. Still, our understanding of how the human brain relates to behavior in the real world and how this link is modulated by biological, social, and environmental factors is limited. To address this, we designed the Healthy Brain...

Emerging efforts toward prevention of stress-related mental disorders have created a need for unobtrusive real-life monitoring of stress-related symptoms. We used ecological momentary assessments (EMA) combined with wearable biosensors to investigate whether these can be used to detect periods of prolonged stress. During stressful high-stake exam (...

Objective: This pilot study aims to identify white matter (WM) tract abnormalities in Autism Spectrum Disorders (ASD) toddlers and pre-schoolers by Diffusion Tensor Imaging (DTI), and to correlate imaging findings with clinical improvement after early interventional and Applied Behavior Analysis (ABA) therapies by Verbal Behavior Milestones Assessm...

The anatomical structure of the thalamus renders its segmentation on 3DT1 images harder due to its low tissue contrast, and not well-defined boundaries. We aimed to investigate the differences in the precision of publicly available segmentation techniques on 3DT1 images acquired at 1.5 T and 3 T machines compared to the thalamic manual segmentation...

Background: Diagnoses of thalamic atrophy in children are based on experts’ judgments. No normative measures exist for aiding objective diagnoses. Our aim was to determine normative two-dimensions(2D) and volume measurements of the thalamus in normally developing children. Methods: MRI images of 245 patients were retrospectively collected. Only par...

Background and purpose: Few articles in the literature have looked at the diameter of the optic nerve on MR imaging, especially in children, in whom observations are subjective and no normative data exist. The aim of this study was to establish a data base for optic nerve diameter measurements on MR imaging in the pediatric population. Materials...