Ravi Bhargava

Ravi Bhargava
University of Toronto | U of T

MD
Medical Director, Physician-Scientist

About

48
Publications
3,645
Reads
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464
Citations
Introduction
Dr. Ravi Bhargava, MD is a Physician Scientist and a healthcare management executive. Completed the Advanced Health System Leadership program from the Rotman School of Management, University of Toronto and is a recipient of the prestigious WOHS Award of Excellence in Management. For the past 15+ years, Dr. Bhargava has been working closely with the hospitals and pharmaceutical industry to foster collaborations and knowledge dissemination. He is involved with emerging drugs, is co-PI in trials, jointly hold grants and has presented trial results in conferences worldwide. Furthermore, Dr Bhargava is a Faculty at the Univ. of Toronto -GIPPEC with affiliation to UHN and has co-authored numerous peer reviewed articles, book chapters and the recent ESMO clinical practice guidelines in Oncology.

Publications

Publications (48)
Chapter
The chapter focuses on the assessment and management of the multidimensional components, while discussing the role of exercise and its impact on the physical, emotional, and psychosocial state of patients with cancer-related fatigue (CRF). It also reviews the mechanism and pathophysiology of CRF and describes the various assessment tools used in cl...
Article
Full-text available
The lack of timely symptom reporting remains a barrier to effective symptom management and comfort for patients with cancer-related palliative care needs. Poor symptom management at home can lead to unwanted outcomes, such as emergency department visits and death in hospital. We developed and evaluated RELIEF, a remote symptom self-reporting app fo...
Article
Full-text available
Background The COVID-19 pandemic has resulted in drastic changes in the global healthcare delivery landscape and has had practical repercussions for cancer survivors. This systematic rapid living review has been undertaken to synthesise the available knowledge regarding the impact of the COVID-19 pandemic in a timely manner. This initial rapid revi...
Article
e24086 Background: Chemotherapy induced nausea and vomiting (CINV) following carboplatin containing chemotherapy regimen remains a considerable problem for cancer patients (pts) despite standard antiemetic prophylaxis. This study was undertaken to prospectively evaluate the incidence of CINV in pts undergoing carboplatin-based chemotherapy receivin...
Preprint
Full-text available
Background: The use of Point-Of-Care Ultrasound (POCUS) has increased rapidly across various medical disciplines due to technological advancements providing high quality POCUS units. POCUS can help clinicians at the bed side with information regarding patient management in real time. However, literature reveals scant evidence of POCUS use in Pallia...
Preprint
Full-text available
Background: The COVID-19 pandemic has resulted in drastic changes in the global healthcare delivery landscape and has had practical repercussions for cancer survivors. This systematic rapid living review has been undertaken to synthesize the available knowledge regarding the impact of the COVID-19 pandemic in a timely manner. This initial rapid rev...
Article
Full-text available
Background: Patients often view "palliative care" (PC) as an approach that is synonymous with end-of-life and death, leading to shock and fear. Differing cultural and social norms and religious affiliations greatly determine perception of PC among diverse populations. Methods: This prospective observational study aimed to explore perceptions of...
Article
Full-text available
Background Anorexia–cachexia syndrome (ACS) is a complex condition in advanced cancer patients, defined by disproportionate loss of skeletal muscle mass, and a lack or loss of appetite. This condition greatly lowers the quality of life and limits the treatment options. ACS is commonly associated with gastrointestinal symptoms such as nausea and vom...
Article
Full-text available
Purpose Initial investigation of the impact of a Cancer Survivorship Clinic following its introduction in February 2017. Methods A systematic chart review of 176 patients enrolled in the Cancer Survivorship Clinic (CSC) who completed a minimum of one follow-up visit after the initial baseline visit. This was assessed using three screening tools: d...
Article
Full-text available
https://www.esmo.org/guidelines/supportive-and-palliative-care/cancer-related-fatigue
Preprint
Full-text available
What this study adds -Implementation of a simple checklist (ChELO) increased safety by preventing ethical and legal errors in a cohort of critically ill patients in a community ICU. -ChELO use resulted in a statistically significant reduction in consent pathway error prevalence and reduction in ICU length of stay which both remained durable after a...
Chapter
Cancer rehabilitation is a process that assists the individual with a cancer diagnosis to obtain optimal physical, social, psychological, and vocational functioning within the limits created by the disease and its treatment. The functional autonomy of patients with cancer is compromised. The severity ranges from negligible to profound at the extrem...
Article
Full-text available
Purpose: Patients are living extended life with advanced cancer making it chronic rather than imminently terminal. Literature on the experience of living with advanced cancer is emerging, indicating ongoing polysymptomatic burden, lack of information, burnout (patients and caregivers), and emotional concerns, all of which contribute to emotional d...
Article
Full-text available
Much has changed in the United States and worldwide since Richard Nixon signed the U.S. National Cancer Act of 1971. [...]
Article
Background Cancer Care Ontario promotes the Edmonton Symptom Assessment System (ESAS) for standardized systematic screening and assessment of symptoms across cancer centers in Ontario, Canada. Attitudes of medical oncologists (MOs), radiation oncologists (ROs), and general practitioners in oncology (GPOs) toward palliative care, and the ESAS were...
Article
Purpose of review: In patients with advanced cancer, AIDS and end-stage organ diseases, symptoms of cachexia syndrome include decrease in appetite, weight loss, decreased performance status, and an increase in the systemic inflammatory response. Inflammatory cytokines and other immune interactions affect the lean tissue mass and body fat. It is ho...
Article
Full-text available
Physicians embrace the concept of rehabilitation, but may think of it only as it relates to restoring function through exercise. We use a broader definition that applies to patients with advanced cancer. Cancer rehabilitation is a process that assists a person with a cancer diagnosis to obtain optimal physical, social, psychological and vocational...
Article
This chapter presents a case study to illustrate the desired skills, attitudes, and knowledge required for cancer rehabilitation and fatigue. It addresses several questions such as: What is rehabilitation and how does it apply to the patient with cancer? What roles do the team members play in rehabilitation? What is cancer-related fatigue? What is...
Chapter
This chapter presents a case study to illustrate the desired skills, attitudes, and knowledge required for cancer rehabilitation and fatigue. It addresses several questions such as: What is rehabilitation and how does it apply to the patient with cancer? What roles do the team members play in rehabilitation? What is cancer-related fatigue? What is...
Article
Electrogastrography (EGG) is a technique used to record gastric myoelectrical activity (GMA). Our aim is to investigate the (1) prevalent patterns of GMA, (2) most frequent gastrointestinal (GI) symptoms reported on the Dyspepsia Symptom Severity Index (DSSI), and (3) EGG diagnosis and correlations with GI symptoms, ghrelin, and inflammatory marker...
Article
OHR118 represents a new class of immunomodulatory and cytoprotective drugs in managing anorexia cachexia. Previously in patients with advanced HIV-AIDS, increases in appetite, strength, and alertness were noted. The objective was to determine the effect of OHR118 on appetite, early satiety, and nutritional intake in patients with advanced cancer. S...
Article
Purpose: Gastroesophageal carcinoma has a 5-year survival rate of 20%. Esophagogastrectomy is a significant life-altering operation which interferes with a patient's ability to eat food as a normal social interaction. Dumping syndrome, delayed gastric emptying, and reflux are encountered after surgery. In addition, loss of appetite and body weight...
Article
Full-text available
The purpose of the study was to determine how frequently each domain of activity was addressed and how frequently specific interventions were used by an occupational therapist (OT) with cancer patients who attended an 8-week Cancer Nutrition and Rehabilitation (CNR) program. Sixty-two patients with cancer were assessed. All received interventions b...
Article
To describe the life altering issues that survivors of a head and neck cancer report post treatment and discuss multidimensional rehabilitation approaches. Published journal articles, literature reviews, research reports, book chapters. Survivors and their family caregivers encounter many changes during the first 3 months following treatment for he...
Article
Full-text available
Malnutrition has been known to be associated with adverse outcomes in cancer patients. Patients who have been and/or are being treated for head and neck cancer have a compromised nutritional status. Nutritional deficits have a significant impact on mortality, morbidity, and quality of life. The wasting in cancer cachexia involves loss of muscle and...

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Projects (2)
Project
The Checklist for Ethical and Legal Obligations (ChELO) is an innovative approach to ensure patient-centred decision-making, and supports healthcare professionals to meet ethical and legal obligations to patients at end-of-life. http://www.cheloproject.ca/