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8
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Introduction
Current institution
Sea Turtle Conservancy Panama
Publications
Publications (8)
Purpose: Temporally feathered radiation therapy (TFRT) for head-and-neck cancer (HNC) radiotherapy combines variable-dose daily subplans to increase the rest time of organs-at-risk (OARs) as sought in intensity modulated radiation therapy (IMRT). While the standard TFRT recommends uniform rest time for each OAR, improved toxicity outcomes may be ac...
Purpose:
To develop a clinical decision-making model for implementation of personalized organ-at-risk (OAR)-sparing adaptive radiation therapy (ART) that balances the costs and clinical benefits of radiation plan adaptations, without limiting the number of re-plannings per patient, and derive optimal policies for head and neck cancer (HNC) radiatio...
Background and Purpose. Prior work on adaptive organ-at-risk (OAR)-sparing radiation therapy has typically reported outcomes based on fixed-number or fixed-interval re-plannings, which represent a one-size-fits-all approach and do not account for the variable progression of individual patients’ toxicities. The purpose of this study was to determine...
Background and purpose
Prior work on adaptive organ-at-risk (OAR)-sparing radiation therapy has typically reported outcomes based on fixed-number or fixed-interval re-planning, which represent one-size-fits-all approaches and do not account for the variable progression of individual patients’ toxicities. The purpose of this study was to determine t...
We propose an extension of two-player zero-sum games, where one player may select available actions for themselves and the opponent, subject to a budget constraint. We present a mixed-integer linear programming (MILP) formulation for the problem, provide analytical results regarding its solution, and discuss applications in the security and adverti...
The intrinsic stochasticity of patients' response to treatment is a major consideration for clinical decision‐making in radiation therapy. Markov models are powerful tools to capture this stochasticity and render effective treatment decisions. This paper provides an overview of the Markov models for clinical decision analysis in radiation oncology....
Tortuguero is a small Caribbean village of Costa Rica, where sea turtles have always played a central role in the culture and economy. Historically, Tortuguero based its economy on the exploitation of natural resources, including marine turtles. However, thanks to long term conservation efforts, policy modifications and a change in the mindset of t...
