Rathish R Nair

• Manager at Torrent Pharmaceuticals

Vitamin D insufficiency affects almost 50% of the population worldwide. An estimated 1 billion people worldwide, across all ethnicities and age groups, have a vitamin D deficiency (VDD). This pandemic of hypovitaminosis D can mainly be attributed to lifestyle (for example, reduced outdoor activities) and environmental (for example, air pollution) f...

Aim of the present study was to screen thirteen plants for their in vitro antibacterial potentiality. The antibacterial activity of aqueous and methanolic extracts of the plants was evaluated against 5 microorganisms by agar well diffusion method. The screening experiments showed that 92% of the plants were active against gram positive bacteria whi...

Objective: The present study was undertaken to evaluate in-vitro antimicrobial activity of methanol, acetone and N, N-dimethylformamide extracts from leaf of Terminalia catappa L. (Combretaceae). Methods: In vi-tro antimicrobial activity of all the extracts was done by agar disc diffusion assay. 91 clinically important strains were used for the stu...

The methanol, acetone and 1,4-dioxan fractions of leaves of Polyalthia longifolia (Sonn.) Thw. were evalu-ated for antibacterial and antifungal activity. 91 clinically important strains were used for the study which were both clinical isolates as well as identified strains. Piperacillin and gentamicin were used as standards for antibacterial assay,...

The antibacterial activity of Eucalpytus citriodora oil was evaluated. The volatile oil was extracted by steam distillation method. The tested bacterial strains were Escherichia coli ATCC 25922, Staphylococcus aureus , Proteus mirabilis NCIM2241, Pseudomonas aeruginosa ATCC27853, Proteus vulgaris NCTC8313, Salmonella typhymurium , Enterobacter aero...

The emergence of antibiotic resistant bacterial strains is a growing problem and is an important concern for patients, physicians, healthcare managers and policymakers as it results in poorer health and economic outcomes. This has led to an urgent global call for new antimicrobial drugs, particularly from natural resources. In the present study, an...

Polyalthia longifolia (Sonn.) Thw. var. pendula is a tree belonging to the family Annonaceae, distributed in the tropical and subtropical regions. The leaves of P. longifolia and its extracts were investigated for its acute toxicity effects in mice. Five different dose levels of drug were administered orally (p.o.) to the animals. The 5 dose levels...

Anticandidal activity of Punica granatum L.. extracts in ethanol, methanol, propanol, acetone, benzyl alcohol, 1,4-dioxan, and N,N.-dimethyl formamide (DMF) is reported. The selection of solvents was on the basis of their polarity. Growth inhibition using the agar ditch diffusion assay was determined on four different strains of Candida. species is...

The objective of the present study was to screen various solvent extracts of Polyalthia longifolia var. pendula (Annonaceae) leaf for anti-inflammatory activity and to evaluate the anti-inflammatory and hepatoprotective potency of the potent solvent extract. Successive extraction was performed with six different solvents, viz. petroleum ether, hexa...

The present communication deals with some studies on the antibacterial, physico-chemical and phytochemical parameters of different extracts of Eucalyptus citriodora leaf. The antibacterial study was performed using the agar ditch method on some clinically important bacteria, namely Pseudomonas pseudoalcaligenes, Proteus vulgaris, Citrobacter freund...

Aqueous and methanol extract of the leaves of Terminalia catappa L., Manilkara zapota L. and Piper betel L. were evaluated for antibacterial activity against 10 Gram positive, 12 Gram negative bacteria and one fungal strain, Candida tropicalis. Piperacillin and gentamicin were used as standards for antibacterial assay, while fluconazole was used as...

The methanol, acetone and N, N-dimethylformamide (DMF) fractions of leaves of Psidium guajava L. were evaluated for antibacterial and antifungal activity. Piperacillin and gentamicin were used as standards for antibacterial assay, while nystatin and flucanazole were used as standards for antifungal assay. 91 clinically important strains were used f...

This study was done to investigate the antimicrobial potentiality of the marine algae collected from different coastal regions of Gujarat and screened for the same. Twenty-six marine algae belonging to Rhodophyceae, Chlorophyceae and Phaeophyceae were screened for their potential antibacterial activity against five clinically important bacterial st...

Methanol extracts of Piper longum L., Piper betle L., Piper attanuatum Buch-Ham. [type-2], Piper hymenophyllum Miq., Piper sarmentosum Roxb., Piper argyrophyllum L., Piper attanuatum Buch.-Ham. [type-1] and Piper chaba Hunter were checked for their antibacterial efficiency against 15 clinically important bacterial strains. Cefotaxime sodium (100 μg...

In the present work, selected plants were screened for their potential antibacterial activity. For evaluating antibacterial activity, both aqueous and organic solvent methanol was used. The plants screened were Ocimum sanctum, Jatropha gossypifolia, Boerhavia diffusa, Azadirachta indica, Solidago virgaurea , and Commelina benghalensis. The antibact...

Ten medicinal plants, namely Commiphora wightii, Hibiscus cannabinus, Anethum gravelons, Emblica officinalis, Ficus religiosa, Ficus racemosa, Ficus benghalensis, Ficus tisela, Mentha arvensis and Mimusops elengi, were screened for potential antibacterial activity against medically important bacterial strains, namely Pseudomonas aeruginosa, Proteus...

Two Schiff bases were synthesized from raceacetophenone: 1) ADS1: 4-ethyl-6-{(E)-1-[(3-nitrophenyl)imino]ethyl}benzene-1,3-diol and 2) ADS3: 4-ethyl-6-{(E)-1-[(2-nitrophenyl)imino]ethyl}benzene-1,3-diol. Then their metal complexes were formed. The metals selected for the preparation of complexes were copper, nickel, iron and zinc. Hence, in total 8...

This study describes the antibacterial activity of two natural and eight synthetic compounds. The two natural compounds were the leaves of Punica granatum and Maytenus emarginata. The eight synthetic compounds were Schiff bases derived from sulfonamide, 4-amino antipyrene and raceacetophenone. Both natural and synthetic compounds were screened for...

In this study, the antibacterial activity of leaf of Punica granatum was investigated. Different solvents used were, water, ethanol, methanol, acetone, propanol, 1,4-dioxan, N,N-dimethylformamide (DMF) and benzyl alcohol. The selection of solvents was on the basis of their polarity. The antibacterial activity of six clinical strains (S. paratyphi,...

Schiff bases derived from sulfonamide, 4-amino antipyrene and raceacetophenone were screened for antibacterial activity against various clinical isolates (obtained from Urine, Blood, Tracheal secretion and Pus). Extracts of these compounds were evaluated on 5 pathogenic strains [E. coli, Pseudomonas aeruginosa, Proteus vulgaris, Klebsiella pneumoni...

Ethanol extract (ETE) and cold aqueous infusion (CAI) of Vitex leucoxylon leaf were evaluated in a battery of tests to define the activity profile of the plant. CAI depressed SMA, antagonised d-amphetamine stereotypy and oxotremorine tremors, shortened the duration of mice immobility in behavioural 'despair' test and lowered serum total cholesterol...

The hypoglycemic and antihyperglycemic activity of various solvent extracts of Polyalthia longifolia var. pendula leaf extracts was evaluated in alloxan induced experimental diabetes in rats. Diabetes was induced using 180 mg/kg i.p. of alloxan consecutively two times at an interval of 24 h. The test drugs were administered for 7 days. On 8 th day...