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Chronic glucocorticoids therapy is commonly complicated by steroid diabetes, while the underlying mechanisms are still elusive. Liraglutide a glucagon like peptide -1 was initially found to induce glycemic control and recently it was found to have many pleotropic effects. However, its role in pancreas remains unknown. So, the present study aims to...
Background: Cisplatin is an alkylating agent that inhibits DNA replication and interferes with proliferation of cancer cells. However, the major limiting factor for its use is the possible development of adverse effects, including ototoxicity. Up till now, the mechanisms of this ototoxicity remain poorly understood. However, induction of oxidative...