Ranjan Bhattacharyya

Murshidabad Medical College, West Bengal, India. · Berhampore

Aim: To evaluate the prevalence of substance use disorder (SUD) and its association with the course and outcome of bipolar disorder (BD). Materials and methods: A total of 773 patients with BD were recruited from 14 centers in different parts of India, and they were evaluated for the prevalence of comorbid substance dependence, course and outcom...

Aim: To evaluate the risk factors associated with lifetime suicide attempts in bipolar disorder (BD) patients. Methodology: 773 BD patients with a duration of illness of at least ten years, currently in clinical remission, were evaluated for suicidal attempts in their lifetime. Those with and without lifetime suicide attempt(s) were compared for...

Background: Behavioral and psychological symptoms (BPS) are usually the expected consequences of dementia. BPS increases morbidity and burden, affects the quality of life, and impacts care costs. However, the symptom characteristics, clinical correlations, and symptom-specific clusters aiding the diagnosis are less well studied, especially in the...

PSYCHOSIS CLINICAL FEATURES A b n o r m a l / d i s o r g a n i z e d b e h av i o r / u n u s u a l appearance Understandable talk, nonsensible speech False beliefs (such as ‘people are going to harm me or give me the poison’) False perception (e.g., hearing voices of people not around) Social withdrawal There had been significant neglect on...

Background Sexual dysfunction (SD) and its effect on our life is an important but less studied topic especially during post-COVID era. This study examines the extent of SD and other mental health predictors and their effect on quality of life. Methods A cross-sectional survey of sexually active adults was conducted in an Indian metro-city. Along w...

Aim Most of the available data on the prevalence and impact of psychotic symptoms on the course of bipolar disorder (BD) is from Western countries. We aimed to study the prevalence of at least one psychotic episode in the lifetime in patients with BD and its association with the long-term course and outcome. Methodology 773 patients were recruited...

Background: Sexual dysfunction(SD) and its effect on our life is an important but less studied topic especially during post-Covid era. This study examines the extent of SD and other mental health predictors and their effect on quality of life. Methods: A cross-sectional survey of sexually active adults was conducted in an Indian metro-city. Along...

Introduction : Mental health is considered as an essential component of health by the World Health Organization. Students may not be able to identify their problem and avoid seeking help often due to reasons of confidentiality or finances. Materials & Methods : In this study, Undergraduate Medical Students of 1st MBBS and 2nd MBBS, who fulfil the i...

Knowing your mental health is an integral part of knowing your health as WHO has categorically mentioned in the definition of Health that 'no health is without mental health'

Psychiatric adverse effects of antibiotics: What clinicians need to know

Aim: This study aimed to evaluate the prevalence of unipolar mania (UM) in a group of patients of bipolar disorder (BD). Additionally, effort was made to evaluate the demographic, clinical and treatment related factors, which distinguish subjects of UM from BD. Methodology: Seven hundred and seventy-three patients with BD, of at least 10 years dur...

Every year on 10th September, World Suicide Prevention day is being observed. The theme of 2021 is ‘Creating hope through action’ will persist till 2023. Since suicide is preventable not inevitable, the awareness building will instill hope which has become more relevant during this pandemic times. In every 40 seconds, someone in this world terminat...

Cyclin D1 as a biomarker is over expressed in indraductal carcinoma in breast not in benign breast diseases. The study has been conducted in the Department of Pathology of a tertiary medical college of eastern India (n=57, d=18 months). The primary aim was to find the correlation between Cyclin D1 with different biomarkers as well as other variable...

Following any natural disaster, tragedy, calamities, there are upsurge of mental health issues found worldwide. COVID 19 is no exception to them. Public health and infection control domains were the first hit at the peak of pandemic. The news and information were bombarded in traditional print and electronic Medias as well as in social Medias. The...

Following any natural disaster, tragedy, calamities, there are upsurge of mental health issues found worldwide. COVID 19 is no exception to them. Public health and infection control domains were the first hit at the peak of pandemic. The news and information were bombarded in traditional print and electronic Medias as well as in social Medias. The...

Aim: This study aimed to evaluate the prevalence of unipolar mania (UM) in a group of patients of bipolar disorder (BD). Additionally, effort was made to evaluate the demographic, clinical and treatment related factors, which distinguish subjects of UM from BD. Methodology: Seven hundred and seventy-three patients with BD, of at least 10 years d...

Aim To explore the prevalence of residual symptoms (both depressive and manic) and their correlates in subjects with bipolar disorder in clinical remission. Methodology This multicentric cross-sectional study included patients in clinical remission recruited across the 14 centers. The patients were evaluated on the Hamilton Depression Rating Scale...

Aim This cross-sectional study aimed to assess the predominant polarity (PP) in patients with bipolar disorder (BD) and the factors associated with PP. Methodology For this study, 773 participants with at least 10 years of illness, were recruited from 14 centres, were evaluated using the National Institute of Mental Health- Retrospective Life Char...

Background: COVID19 pandemic poses a unique medical challenge to humanity in recent times. The psychological impact of ‘lockdown’ as a social distancing strategy among children needs to be studied well. Aim: To assess the psychological impact of ‘lockdown’ on behaviour of children and adolescents. Methods: An online survey was conducted among par...

Index case presented with insidious onset psychotic symptoms of 6 months duration characterised by excitement, smiling and muttering to self, catatonic posturing, negativism, and periods of mutism, irritability, episodes of aggression and poor self-care which were gradually progressive in nature. For the last 2 months preceding his presentation to...

Bipolar Disorder Course and Outcome Study from India (BiD-CoIN study): Sample Description & Methods

Aim To evaluate the prescription pattern of patients with BD, currently in clinical remission. Additional aim of the study was tocompare the prescription pattern across different study centres. Methodology Prescription of 773 patients, currently in clinical remission, recruited from the outpatient setting of 14 General Hospital Tertiary Care Units...

Background: Metabolic syndrome (MS) refers to a clustering of metabolic risk factors and compared to the general population, the prevalence of MS and its components is higher in populations with mental illness across all major diagnostic groups. Aim was to study the prevalence and correlates of MS in a cohort of psychiatric outpatients in a tertiar...

Introduction : With recent advancement of molecular biology, the prognosis and therapeutic strategy of breast tumours can be ascertained and predicted for a better prognosis. Aims and objectives : The primary aim was to find out the correlation Her2Neu scoring and status with molecular classification of the breast. As the secondary outcome measure...

Objectives: This multicentric study from India aimed to evaluate the long term course and outcome of bipolar disorder (BD). Method: Seven hundred and seventy-three participants diagnosed with BD, attending 14 outpatient clinic centers across the country, were evaluated using the National Institute of Mental Health- Retrospective Life Charts to asse...

Objectives This multicentric study from India aimed to evaluate the long term course and outcome of bipolar disorder (BD). Method Seven hundred and seventy-three participants diagnosed with BD, attending 14 outpatient clinic centers across the country, were evaluated using the National Institute of Mental Health- Retrospective Life Charts to asses...

A lady with early onset cognitive impairment with movement disorder and elevated mood, grandiosity, distractibility, flight of ideas, pressure of speech presented in outpatient department and initially diagnosed as Bipolar disorder with early onset parkinsonism and Frontotemporal dementia. She later developed vertical gaze palsy with slow saccadic...

Porphyrias are a group of inherited or acquired disorders of certain enzymes in the heme bio-synthetic pathway (also called porphyrin pathway). They are broadly classified as acute (hepatic) porphyrias and cutaneous (erythropoietic) porphyrias, based on the site of the overproduction and accumulation of the porphyrins or their chemical precursors....

Background: Nicotine dependence, depression, diabetes mellitus, hypertension, and hypothyroidism are risk factors of sexual dysfunction. Aims and Objectives: The present study aims to find the prevalence of sexual dysfunction and the various sexual response cycle domains in individuals with nicotine dependence with and without comorbidities. Materi...

As Covid-19 hit the world, almost all the countries are tackling it with lockdown, increased testing, and other strategies. The developed countries have passed their peak, whereas developing countries are yet to flatten the 'hammer curve'. More than 40 million tests have been carried out till now and still the demand is ever increasing. As actual c...

Background: COVID-19, like every other pandemic, has imposed an unprecedented threat to doctors' physical and mental health. Literature in this area is sparse. The present study has been done to explore the knowledge, attitude, and behavior of doctors regarding this pandemic and how it influences their depression, anxiety, and stress level. Materia...

Background: Temperament in children and adolescents acts as a trait marker which can predict behavioral abnormalities. There was no systemic study in India which has compared the temperamental, behavioral and cognitive changes associated with this hemoglobinopathy among thalassemia major (TM) group. Materials and methods: The specific objectives...

The World Health Organization (WHO) has estimated that by 2021, depression will be the second largest cause of the global disease burden. But, cases of depressive disorders have increased in both adults and among children, with a prevalence of 0.3% to 1 7.8% in children below 13 years old. Major depression is an episodic, recurring disorder charact...

General anesthesia (GA) is the choice for laparoscopic cholecystectomy (LC). Spinal anesthesia (SA) is usually preferred in patients where GA is contraindicated. In this study, SA was used in 67 patients in whom LC was planned (study group). LC has been conventionally done under GA. Regional anesthesia is usually preferred in patients where GA is c...

Expert opinion on Lamotrigine in the management of Bipolar depression.

Marriage is a formal union of a man and woman by which they become husband and wife. Rape is the forcible seizure or the ravishment of a woman without her consent by force, fear or fraud. Marital Rape is the unwanted intercourse by a man on his wife obtained by force or physical violence or when she is unable to give consent. It is relatively new t...

Background Down syndrome, most common chromosomal abnormality leading to intellectual disability is being diagnosed by Karyotyping. Due to cost constraints, parents couldn’t afford to do Karyotyping which causes delay in individual and family interventions. Introduction Down syndrome has characteristic morphological features. The minor physical an...

The current trends in psychiatry show that psychiatrists focus their clinical practiceon psychopharmacological treatments as the lynchpin of care. Psychotherapy and psychosocial interventions take the back seat. Effectiveness studies like STEP BD & STAR D in depression highlight the limitations of a bio bio model and the need for a biopsychosocial...

Chapter 19,20,21

Bengali article on Mudradosh

Deutrabenazine is indicated in the management of chorea associated with Huntington’s disease and in the treatment of Tardive dyskinesia in adults by US FDA. However, it should be used with a pinch of salt, as it can raise the risk of depression and suicidal thoughts with unusual behavioural abnormalities specially in patients with Huntington’s dise...

Introduction: General anaesthesia is choice of laparoscopic cholecystectomy (GA). Spinal anaesthesia is usually preferred in patients where general anaesthesia is contraindicated. In this study, the Spinal anaesthesia was used in 67 patients in whom LC was planned (study group). Methods: Laparoscopic cholecystectomy(LC) has been conventionally done...

The communication between G. S Bose and Sigmund Freud is a well-documented fact, and philosophical blend of rich cultural experiences is unique to modification of traditional psychoanalysis in the context of development of psychiatry in West Bengal. The Calcutta lunatic asylum was established at Bhowanipore, and first general hospital psychiatric u...

Suicide is the one of the emerging causes of death among adolescents in India. The sociodemographic factor in India is different from the western counterpart. With a global mortality rate 16 per 1,00,000 population there is one attempt in every 3 seconds and one death in every 40 seconds globally (WHO2011). Beyond Durkheim’s sociological typology,...

Observation of WSPD’ 17 by IPSWB & IAPPWB

A 7.5 years girl presented with myoclonic jerks with prolonged duration coming progressively at shorter intervals for last six moinths. There was declining academic performances. The dystonic, dyskinetic movements and ataxia were there for last three months. The stages were progressing too rapidly. IgG antibody titre to measles virus was found to b...

Power point presentation on World AIDS day.

A 17 year aged adolescent female from lower socioeconomic status, presented to the OPD with complaints of excessive water intake. The diagnosis was confirmed as Psychogenic polydipsia (PPD) associated with behavioural problems like conduct disorder, with disinhibited behaviour. During the episode of polydipsia, no signs of severe water intoxication...

In a developing country like India, the time is more critical and there is no denying of fact that India is male chauvinistic society and females are not considered to be at par with the males. At the early stage of life they are serving father, then husband after that child and lastly grandchild. The child marriage is a serious social crisis world...

Background: Information regarding paternal involvement, father-child dynamic interactions and father's influence on child development is lacking. Introduction: the parental anger is linked with behavioral problems and there is a need for prevention or early interventions for fathers that builds emotion socialization and improves father-child connec...

The use of virtual and augmented reality technology in medicine to improve psychological and physical health is not new and has an emerging role in the treatment of many disorders. Pokemon Go takes a children's game outdoors in which the real and the virtual collide, and creates an instant global sensation. Even adults today are hunting for monster...

Abstract Background: Scalp dysesthesia is a common mode of presentation in rural West Bengal. The study aims at finding radiological correlation withbnimaging of cervical spine with the presenting symptoms. Introduction: Most of these cutaneous pain symptoms are not attributed to any pathophysiology. The range of complaints vary widely from tinglin...

Introduction: The parental anger is linked with behavioral problems and there is a need for prevention or early interventions for fathers that builds emotion socialization and improves father-child connection. Methodology: The systemic review had been done with only existing recent literatures keeping in mind cross-cultural variations. The impact o...

Patients who achieve full remission are more likely to return to normal psychosocial functioning Consequences of not achieving remission: Affect the course of the disease Healthcare and societal cost Patients who achieve remission but have residual symptoms are more likely to relapse than those without residual symptoms

The modern gadgets and technology has become predominant determinants of socio-economic status and not only is restricted to teenagers but is spreading fast across generations. Addiction to modern technology is causing significant loss in productivity as well as problems in interpersonal relationship.

Amusulpride has completed successful journey of 10 years in Indian Market. To retrospect the efficacy and outcome of this atypical antipsychotic has been critically analyzed in this presentation.

There are reviews about portrayal of Psychiatry in print and electronic media, Bollywood movies. Impact of cine media is extremely important in regional movies where actors and actresses are being worshipped as god. Initial stigmatization about madness is gradually changing to some strong social messages. 'Bollywood' films generally feature strong...

24 yrs old lady, married for 2 years with the intention of remaining lifelong lovers and partners following a relationship of 4 years. Intense emotional attachment, dependency and expectations from hubby. She had mood symptoms, irritability , used to get annoyed in college days. Experiencing marital discord since 1 year which was aggravated followi...

Introduction: The trend of using E-cigarettes is growing day by day especially among youths in city. Vaping in a prefilled battery operated refill activates reward circuit. Methodology: The systemic review of available literatures including pubmed, google scholar, science direct, cochrane database has been reviewed with the available search engines...

Introduction: The management of left colonic obstruction is a real clinical challenge for surgeons. The resection with on table lavage and anastomosis is the cornerstone of surgical management of large gut obstruction. Methodology: Among the left colonic obstructions, 40 samples included in this non-randomized, longitudinal study in a prospective c...

Background : Congenital muscular dystrophy (CMD) refers to a group of muscular dystrophies that become apparent in early infancy or at birth. Muscular dystrophies are mostly genetic and a degenerative disease primarily affects voluntary muscles.Introduction : Alpha dystroglycanopathies both phenotypically and genetically are heterogeneous group of...

Suchibai, the bengali terminology of Obsessive Compulsive disorder is known for its existence for times immemorial. Predominantly the women who remain in oppressive state in traditional, conservative customs following marriage in in-laws house exhibits more this disorder. The article is meant for general audience to build up awareness for this diso...

1. The modern gadgets and technology have become predominant determinants of socioeconomic status and not only is restricted to teenagers but is spreading fast across generations. 2. Addiction to technology is causing significant loss of productivity as well as problems in interpersonal relationships. 3. It has been postulated that rather than a se...

Introduction: Vilazodone is a SERT inhibitor and partial agonist of 5HT1A receptor introduced as a new antidepressant. The dual mechanism of action attributes to faster onset of antidepressant action and more rapid improvement of symptoms. Methodology: The systemic review of available literatures including pubmed, google scholar, science direct, co...

The article deals with two rare cases of Autoerythrocyte sensitization Syndrome that presented in the outpatient department of psychiatry of a rural hospital over a period of time. Autoerythrocyte sensitisation syndrome or Diamond-Gardner syndrome is a rare disorder characterized by painful and spontaneous purpura occurring in women with mental hea...

Background: Tuberous sclerosis complex is a neurocutaneous syndrome inherited as autosomal dominant manner. It presents with CNS, dermatological manifestations and other systemic involvement. Methods: A case of male adolescent of 13 years age who presented in tertiary care OPD with strong family history of intellectual disability. The history obtai...

Background: Penfluridol is oral long acting depot antipsychotic introduced in 1970s. The re-emergence of the molecule in the practicing field draws attention of clinicians. Objectives: The systematic search and review of literature done in order to find current perspectives of use of Penfluridol. Methods:Systematic search of prospective clinical re...

Stigma and discriminations are significant barriers in mental illnesses. The biulding and spread of awareness is the call for the day. Each year the 10 th october is being celebrated with a theme relevant to current scenario. The theme of the year 2015 is Dignity in Mental Health which imparts respect that a mentally ill person and his or her famil...

Background: The alleged murder of daughter by media tycoon mother with suppression of fact for three years revealed and widely circulated in media in last few weeks. Almost every leading print and electronic media highlighted and broadcasted the news in prime time. Methods: The narration of the event with media reports and introspection in the rea...

Introduction: The police officials on 11 th June, 2015 recovered a charred body of a 77-year-old man, a fully-clothed skeleton of a woman in bedrooms, two bags full of bones of dogs with only living person, a man in his mid-40s in the house in Kolkata. Methodology: The event has been described as the reports collected from media sources, police and...

Background: Metastasis to the brain parenchyma is the single most frequent neurologic complication of several common neoplasms, including lung cancer, breast cancer, and melanoma. Case summary: A 50 year old male presented with right sided weakness with severe headache and mild respiratory distress. This patient presented with mainly symptoms of ce...

Ali H, Sinha A, Mondal K, Bhattacharyya R, Roy A, Tudu B.Case Report of Rheumatoid Vacuities Leading to Recurrent Sloughing Ulcer of Skin.Int. J. Nur. Edu. and Research 2014;2: 254-25

Introduction Various masses arise from sinonasal tract and nasopharynx, which are embryologically distinct. Aims and objectives A cross-sectional study for 1 year in a tertiary care hospital was carried out. Materials and methods Either incisional biopsy or surgical excision sample with proper history and imaging was collaborated. Results The total...

Paroxetine has been introduced in1993used for the treatment of depression, panic, anxiety, obsessive compulsive disorders (OCD) and other related disorders. Paroxetine has the strongest inhibition of serotonin uptake but is less specific than other SSRIs. The FDA approval in adult population are Major depressive disorder, obsessive compulsive disor...

At the neuromuscular junction, synaptic action increases the probability that an action potential will occur in the postsynaptic muscle cell; indeed, the large amplitude of the EPP ensures that an action potential always is triggered. Whether a postsynaptic response is an EPSP or an IPSP depends on the type of channel that is coupled to the recepto...

Background: Intellectual disability is the clearest example of the mixture of medical and social system models. People with intellectual disability do not represent homogenous groups. Their unmet needs and impact on parents as caregivers also vary especially with changing social milieu, socio economic status and ethnicity. Objectives: To assess the...

Caregiving in Dementia is a challenging task globally and home hospice is being touted as alternative way to reduce end of life care burden. In the present work an attempt has been done to assess the caregivers burden, demographic comparison, end of life care management and the data obtained uring the study was compared with the data available in t...

A lady aged 50 yrs presented with multiple small and large joint pain with severe body ache. She also gave history of recurrent skin ulcers which is very deep almost extending to the bone. The ulcers heal with scarring by the standard treatment of Rheumatoid Arthritis and Steroid. One may misinterpret the diagnosis of rheumatoid vasculities present...