Rania Abou-Samra

Nestlé S.A. · Nestlé Health Science

Because the source of protein may play a role in its satiating effect, we investigated the effect of different proteins on satiation and short-term satiety. Two randomized single-blind cross-over studies were completed. In the first study, we investigated the effect of a preload containing 20 g of casein, whey, pea protein, egg albumin or maltodext...

Dietary fat has frequently been blamed for the increase in prevalence of obesity (Bray et al., 2004). Epidemiological studies have demonstrated a positive relationship between high-fat diets and excess energy intake due to their high energy density and palatability (Prentice and Poppitt, 1996). However, this association is confounded by differences...

In cohort studies, insoluble fiber has been associated with a reduced risk of obesity and diabetes; however, compared with soluble fiber, its role in the regulation of short-term food intake (FI) and satiety has received little attention. Our aim was to compare the effects of a high-insoluble-fiber (HF) cereal with a low-fiber (LF) cereal on FI, su...

Insoluble fiber consumption is associated with reduced risk of obesity and diabetes, but its mechanisms of action are unknown. The objective was to describe the effect of insoluble fiber on appetite, short-term food intake, and blood glucose (BG) before and after a meal 75 min later in healthy men. In a crossover design, high-fiber (HF; 33 g insolu...

To determine the effect of hyperinsulinemia on food intake and plasma concentrations of glucose and food intake regulatory hormones in men after a glucose drink. Cross-sectional clinical intervention study of the effect of a glucose drink on food intake regulation. Thirty-three normoinsulinemic (NI) (body mass index (BMI)=25.3+/-0.6; age=41.4+/-2.4...

Food intake is regulated in both the short- and long-term by a complex physiological system that involves neuroendocrine pathways that are both distinct and overlapping. The underlying causes and mechanisms of the dysregulation of food intake in obesity is poorly understood; however, it is clear that dietary components interact with the physiologic...

Obesity's protective effect on bone density may be mediated through increased muscle mass, fat mass, increased estrogen, and possibly insulin and leptin levels. To determine the impact of leptin and insulin on bone metabolism, we studied 48 obese normally cycling premenopausal women (age, 31 +/- 10 yr; body mass index, 35.7 +/- 5 kg/m2): 28 insulin...