Randall DeSouza Ordovich Clarkson

• Doctor of Medicine
• Professor at Grand Canyon University

This presentation explores Loyalty Dynamics Theory (LDT), a multidisciplinary framework that examines the biopsychosocial and philosophical underpinnings of loyalty and pro-social behavior. LDT integrates insights from evolutionary biology, psychology, sociology, economics, philosophy, and theology to define well-adjusted loyalty as a virtue distin...

This presentation explores the uses and implications of generative AI in pedagogy. It highlights the potential benefits of AI tools like LLMs for summarizing materials, creating educational resources, and assisting in research, while also acknowledging challenges such as bias and the need for human oversight. Specific AI tools, including Consensus...

The purpose of our research is to seek novel prophylactic treatments for Parkinson's Disease (PD). Metformin and psilocybin have previously shown neuroprotective properties and potential therapeutic applications. Our research focus on metformin and psilocybin derivatives as protective agents against PD.

Background & aim: Treatment of Parkinson's disease (PD) has remained largely unchanged and focuses primarily on symptomatic relief through activation of dopaminergic pathways. Currently, there are no proven pro-phylactic approaches to the prevention of PD. This systematic review seeks to compare two separate compounds , metformin (MTF) and psilocyb...

Cell models and MTT assay have demonstrated significant cytoprotection in SH-SY5Y cells against both EtOH, DMSO, and EtOH+DMSO when treated with MTF as well as norpsilocin. MTT assay protocols demonstrate maximum protection with the use of 2.5μL dosages of both compounds. Cytotoxic effects of compounds become evident with increased dosage (i.e. 50μ...

This presentation explores the history and modern applications of entheogens, particularly psilocybin, in behavioral health and neuroscience. The text traces psilocybin's use from ancient spiritual practices in Mesoamerica to its modern resurgence in research for treating depression, anxiety, PTSD, and end-of-life distress. Key figures like Richard...

Poster was presented at the AZ Physiological Society conference at Midwestern University on October 28, 2023

Background: Some studies suggested that teaching anatomy with a virtual reality simulator would greatly enhance medical education. The purpose of this work is to analyze the available literature to determine the effectiveness of virtual reality as a learning tool for anatomy teaching in medical schools. Materials and Methods: This literature review...

Background: Some studies suggested that teaching anatomy with a virtual reality simulator would greatly enhance medical education. The purpose of this work is to analyze the available literature to determine the effectiveness of virtual reality as a learning tool for anatomy teaching in medical schools. Materials and Methods: This literature review...