Rana I. Mahmood

Al-Nahrain University · Department of Biomedical Engineering

Purpose-In the developing field of nano-materials synthesis, copper oxide nanoparticles (NPs) are deemed to be one of the most significant transition metal oxides because of their intriguing characteristics. Its synthesis employing green chemistry principles has become a key source for next-generation antibiotics attributed to its features such as...

This study investigated for the first time a simple bio-synthesis approach for the synthesis of copper oxide nanoparticles (CuO NPs) using Annona muricata L (A. muricata) plant extract to test their anti-cancer effects. The presence of CuONPs was confirmed by UV–visible spectroscopy, Scanning electron microscope (SEM), and Transmission electron mic...

This study assesses the antioxidant characteristics of folate-methotrexate that has been conjugated to bovine serum albumin nanoparticles (FO-MTX-BSA-NPs) as well as its cytotoxic impacts on MCF-7 (human breast adenocarcinoma), HepG2 (human liver cancer) and PC3 (human prostate cancer) cell lines in vitro. A 2,2-diphenyl-1-picrylhydrazyl (DPPH) ass...

One of the most widely used biological and medical instruments are the microscopes. Many new modalities have been developed by constant advancement in the field of microscopy, but their relative sizes and their complexity, and their costs often hinder the usefulness of these instruments in the wider general community and many field environments. In...

One of the most prevalent death causes among women worldwide is breast cancer. This study aimed to characterise and differentiate the proteomics profiles of breast cancer cell lines treated with Doxorubicin (DOX) and Doxorubicin-CaCO3 -nanoparticles (DOX-Ar-CC-NPs). This study determines the therapeutic potential of doxorubicin-loaded aragonite CaC...

Background One of the main anthracycline antibiotics is doxorubicin which has been used as an efficient antitumor drug. Doxorubicin is being used in the therapy of different cancers like, breast cancers, cervical cancers, and others. Methods In this research, we examined the reactive oxygen species and antioxidant enzymes of patients with breast c...

The second most predominant cancer in the world and the first among women is breast cancer. We aimed to study the protein abundance profiles induced by lectin purified from the Agaricus bisporus mushroom (ABL) and conjugated with CaCO3NPs in the MCF-7 breast cancer cell line. Two-dimensional electrophoresis (2-DE) and orbitrap mass spectrometry tec...

The second-largest cancer in the world and the first among women is breast cancer. The acidic microenvironment of tumour cells requires a pH-sensitive delivery mechanism for improving drug release. In this study, the feasibility of using pH-sensitive CaCO3 nanoparticles with sustained-release performance and slow degradability as carriers for lecti...

The acidic microenvironment of tumour cells requires a pH-sensitive delivery mechanism for improving drug release. In this study, we investigated the feasibility of using pH-sensitive ACC nanoparticles with sustained-release performance and slow degradability as carriers for lectins isolated from edible mushroom Agaricus bis-porus (ABL) that exhibi...

Infertility is one of the main health problem in developing countries, and among the complex issues in medicine. In recent years, medical plants has been widely used in the treatment of infertility. This study aims to investigate the role of mix extract of three plants(Eruca sativa , Apium graveolens L.,and Nigella Sativa) on follicle stimulating h...

The aim of the current study was to investigate the potential mechanism of Hypoglycemic and hypolipidemic action of the mixture extract of three plants (Artemisia sieberi, Nigella sativa and T. polium) and its impact on some biochemical parameters in alloxan induced diabetic rats. Rats have been induced diabetic by injected with single dose of allo...

The study was current to examine the antidiabetic effects of administration of aqueous extracts of Salvia officinalis leaves in alloxan(100 mg/kg) induced diabetic rats and reveal the effect of Salvia officinalis in the the liver and testicular function. The present study aimed to evaluate the effects of aqueous extracts of Sage leaves (Salvia offi...

Abstract his study was designed to investigate the effect of crud alcoholic extract of fenugreek seeds (Trigonella foenum-graecum) on the levels of Prolactin and Leutinizing hormones in male rabbits. Forty eight male rabbits were used in this study. The animals were divided into four main groups; the first group received 1ml of DW (control), while...

This study was designed to investigate the effect of crud alcoholic extract of fenugreek seeds (Trigonella foenum-graecum) on histology of liver and kidney, and levels of Prolactin and Leutinizing hormones in male rabbits. Forty eight male rabbits were used in this study. The animals were divided into four main groups, the first group received 1ml...